# Fusion Gene Detector

> Gene fusion detection skill for oncology applications with multiple caller integration

- Skill: `a5c-ai/fusion-gene-detector` (Agent Skill)
- Install (CLI): `npx skillmds@latest add a5c-ai/fusion-gene-detector`
- Raw SKILL.md: https://api.skillmd.com/api/skills/a5c-ai/fusion-gene-detector/raw
- Safety review: pending (external: skill-scanner PASS, skillspector PASS)
- Works with: Claude Code, Claude.ai, OpenAI Codex
- Category: Integrations & APIs
- Author: a5c-ai (https://skillmd.com/u/a5c-ai)
- Updated: 2026-09-09
- Page: https://skillmd.com/skills/a5c-ai/fusion-gene-detector

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# Fusion Gene Detector Skill

## Purpose
Enable gene fusion detection for oncology applications with multiple caller integration.

## Capabilities
- RNA-based fusion calling
- DNA-based fusion detection
- Multi-caller consensus
- Visualization of fusion events
- Known fusion annotation
- Clinical actionability assessment

## Usage Guidelines
- Use multiple callers for sensitivity
- Build consensus from different algorithms
- Annotate with known fusion databases
- Visualize fusion breakpoints
- Assess clinical actionability
- Document caller combinations

## Dependencies
- STAR-Fusion
- Arriba
- FusionCatcher

## Process Integration
- Tumor Molecular Profiling (tumor-molecular-profiling)
- RNA-seq Differential Expression Analysis (rnaseq-differential-expression)