# Systematic Review

> Conduct comprehensive literature searches, quality assessments, evidence synthesis, and meta-analyses

- Skill: `a5c-ai/systematic-review` (Agent Skill)
- Install (CLI): `npx skillmds@latest add a5c-ai/systematic-review`
- Raw SKILL.md: https://api.skillmd.com/api/skills/a5c-ai/systematic-review/raw
- Safety review: pending (external: skill-scanner PASS, skillspector PASS)
- Works with: Claude Code, Claude.ai, OpenAI Codex
- Category: Research & Search
- Author: a5c-ai (https://skillmd.com/u/a5c-ai)
- Updated: 2026-09-09
- Page: https://skillmd.com/skills/a5c-ai/systematic-review

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# Systematic Review Skill

Conduct comprehensive literature searches, quality assessments, and evidence synthesis including meta-analysis.

## Overview

The Systematic Review skill enables conducting comprehensive literature searches, quality assessments, evidence synthesis, and meta-analyses following established protocols for rigorous evidence-based research and policy making.

## Capabilities

### Search Strategy
- Database selection
- Search term development
- Boolean operators
- Citation tracking
- Grey literature inclusion

### Study Selection
- Inclusion/exclusion criteria
- Screening procedures
- Dual review process
- Disagreement resolution
- PRISMA documentation

### Quality Assessment
- Risk of bias tools
- Quality checklists
- Evidence grading
- Study appraisal
- Bias identification

### Evidence Synthesis
- Narrative synthesis
- Vote counting
- Framework synthesis
- Thematic synthesis
- Realist synthesis

### Meta-Analysis
- Effect size calculation
- Heterogeneity assessment
- Fixed/random effects
- Publication bias
- Sensitivity analysis

## Usage Guidelines

### When to Use
- Synthesizing evidence
- Informing policy
- Identifying research gaps
- Establishing consensus
- Supporting decisions

### Best Practices
- Register protocol
- Document thoroughly
- Use multiple reviewers
- Assess bias
- Update regularly

### Integration Points
- Quantitative Methods skill
- Qualitative Analysis skill
- Policy Communication skill
- Academic Writing and Publication skill

## References

- Literature Review and Synthesis process
- Policy Impact Assessment process
- Policy Research Analyst agent
- Mixed Methods Research Coordinator agent