# Reproducibility Checklist

> Reproducibility Checklist — Open Science Best Practices

- Skill: `biotender-max/reproducibility-checklist` (Agent Skill)
- Install (CLI): `npx skillmds@latest add biotender-max/reproducibility-checklist`
- Raw SKILL.md: https://api.skillmd.com/api/skills/biotender-max/reproducibility-checklist/raw
- Safety review: pending
- Works with: Claude Code, Claude.ai, OpenAI Codex
- Category: Coding & Dev Tools
- Author: BioTender-max (https://skillmd.com/u/biotender-max)
- Updated: 2026-09-17
- Page: https://skillmd.com/skills/biotender-max/reproducibility-checklist

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# Reproducibility Checklist — Open Science Best Practices

## Overview
Ensure research is reproducible, transparent, and meets open science standards.

## Pre-Registration
- [ ] Study registered on ClinicalTrials.gov, OSF, or AsPredicted before data collection
- [ ] Primary outcome and analysis plan pre-specified
- [ ] Deviations from pre-registration documented and justified

## Data Availability
- [ ] Raw data deposited in domain repository (GEO, PDB, PRIDE, Zenodo, Dryad, Figshare)
- [ ] Data dictionary/codebook provided
- [ ] Sensitive data: de-identification method documented, access controls described
- [ ] DOI assigned to dataset

## Code Availability
- [ ] Analysis code in public repository (GitHub, GitLab, Zenodo)
- [ ] Environment specification (requirements.txt, conda env, Docker, renv.lock)
- [ ] Random seeds fixed and documented
- [ ] README with reproduction instructions

## Materials
- [ ] Reagent catalog numbers, lot numbers, manufacturer
- [ ] Custom materials: synthesis protocol or request process
- [ ] Cell lines: STR authentication, mycoplasma testing
- [ ] Antibodies: RRID or Antibody Registry ID

## Statistical Reporting
- [ ] All statistical tests, parameters, and software versions reported
- [ ] Effect sizes and confidence intervals (not just p-values)
- [ ] Multiple comparison correction method stated
- [ ] Sample size justification (power analysis)

## Reporting Standards
- [ ] Applicable guideline followed (STROBE/CONSORT/PRISMA/ARRIVE/MIQE)
- [ ] Checklist completed and submitted with manuscript