# Candidate Ranking

> Rank peptide variants using stability heuristics and hotspot protection; emit top candidates.

- Skill: `lamm-mit/candidate-ranking` (Agent Skill, multi-file: 3 files)
- Install (CLI): `npx skillmds@latest add lamm-mit/candidate-ranking`
- Raw SKILL.md: https://api.skillmd.com/api/skills/lamm-mit/candidate-ranking/raw
- Safety review: pending
- Works with: Claude Code, Claude.ai, OpenAI Codex
- Category: Coding & Dev Tools
- Author: lamm-mit (https://skillmd.com/u/lamm-mit)
- Updated: 2026-09-17
- Page: https://skillmd.com/skills/lamm-mit/candidate-ranking

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# Candidate Ranking

Ranks candidates based on a simple weighted score:
- stability_score (heuristic)
- penalty for hotspot mutations if hotspot positions provided
- penalty for edit distance vs reference sequence if provided

## CLI
```bash
python3 scripts/run.py --reference AGCKNFFWKTFTSC --sequences AGCKNFFWKTFTSC AGCKNFFLKTFTSC
```