# Scientific Protein Domain Family

> Protein domain and family skill. InterPro/Pfam domain annotation, protein family classification, domain architecture analysis, and functional domain prediction.

- Skill: `nahisaho/scientific-protein-domain-family` (Agent Skill, multi-file: 2 files)
- Install (CLI): `npx skillmds@latest add nahisaho/scientific-protein-domain-family`
- Raw SKILL.md: https://api.skillmd.com/api/skills/nahisaho/scientific-protein-domain-family/raw
- Safety review: pending
- Works with: Claude Code, Claude.ai, OpenAI Codex
- Category: Coding & Dev Tools
- Author: nahisaho (https://skillmd.com/u/nahisaho)
- Updated: 2026-09-17
- Page: https://skillmd.com/skills/nahisaho/scientific-protein-domain-family

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# Protein domain and family

Protein domain and family skill. InterPro/Pfam domain annotation, protein family classification, domain architecture analysis, and functional domain prediction.

## Use This Skill When

- InterPro/Pfam domain annotation.
- Protein family classification.
- Domain architecture analysis.
- Functional domain prediction.

## Required Inputs

- Research objective, decision target, or hypothesis.
- Available data, source constraints, and domain assumptions.
- Required outputs, success metrics, and deadline or reproducibility constraints.

## Workflow

1. Confirm scope, assumptions, and the exact artifact set to save.
2. Apply the narrowest domain method that answers the request with defensible evidence.
3. Save code, tables, figures, and intermediate outputs to files instead of chat-only output.
4. State limitations, uncertainty, and any validation or sensitivity checks performed.
5. Append skill selection, handoff I/O, and file writes to `logs/process-log.jsonl`.

## Deliverables

- `report.md`: concise method, results, interpretation, and file inventory in the user's language.
- `results/`: structured outputs, metrics, model artifacts, or extracted findings.
- `figures/`: English-only charts, diagrams, or panels when visual output is needed.
- `data/`: processed or derived datasets when transformation occurs.

## Quality Gates

- The selected method matches the scientific question and stated assumptions.
- Outputs are reproducible, saved to files, and traceable from inputs to conclusions.
- Missing data, uncertainty, bias, and hard limits are made explicit.
- `report.md` and `logs/process-log.jsonl` reference the generated artifacts.