# Target Assessment

> Assess a biological target's druggability and risk into a go / no-go recommendation.

- Skill: `tinyhumansai/target-assessment` (Agent Skill)
- Install (CLI): `npx skillmds@latest add tinyhumansai/target-assessment`
- Raw SKILL.md: https://api.skillmd.com/api/skills/tinyhumansai/target-assessment/raw
- Safety review: pending (external: skill-scanner PASS, skillspector PASS)
- Works with: Claude Code, Claude.ai, OpenAI Codex
- Category: Coding & Dev Tools
- Author: tinyhumansai (https://skillmd.com/u/tinyhumansai)
- Updated: 2026-09-22
- Page: https://skillmd.com/skills/tinyhumansai/target-assessment

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# Target Assessment

Judge whether a target is worth a program — how druggable it is, and what could
kill it — before resources go in.

## When to use

- A target is proposed and needs a rigorous read before committing.
- Two targets compete for the same program slot.

## Steps

1. **Establish** the biological rationale linking target to disease.
2. **Assess** druggability — structure, binding sites, and modality fit.
3. **Scan** the competitive and IP landscape around the target.
4. **Surface** the risks: safety liabilities and validation gaps.
5. **Weigh** it into a go / no-go with the reasoning.

## Output

A target assessment: rationale, druggability, landscape, risks, and a go /
no-go, following the [[Research standards]]. The operator decides to commit.