# Risk Of Bias Assessment

> Assess methodological bias using RoB2, PROBAST, or QUADAS-2 validated tools

- Skill: `yogsoth-ai/risk-of-bias-assessment` (Agent Skill, multi-file: 2 files)
- Install (CLI): `npx skillmds@latest add yogsoth-ai/risk-of-bias-assessment`
- Raw SKILL.md: https://api.skillmd.com/api/skills/yogsoth-ai/risk-of-bias-assessment/raw
- Safety review: pending
- Works with: Claude Code, Claude.ai, OpenAI Codex
- Category: Coding & Dev Tools
- Author: yogsoth-ai (https://skillmd.com/u/yogsoth-ai)
- Updated: 2026-09-17
- Page: https://skillmd.com/skills/yogsoth-ai/risk-of-bias-assessment

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# Risk of Bias Assessment SOP

Conduct structured risk-of-bias assessment for individual studies using the appropriate validated tool (RoB 2.0, ROBINS-I, QUADAS-2, PROBAST, or Newcastle-Ottawa Scale).

## When to Use

- During quality assessment of each included study
- When deciding sensitivity analysis groupings
- When assessing GRADE certainty (risk of bias domain)

## Input

- `study_metadata`: Study characteristics, methods description, and results
- `study_design`: The study design (RCT, non-randomized, diagnostic, prediction model, observational)

## Output

Domain-level risk-of-bias judgments with supporting rationale for each signaling question.

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## Available SOPs

Optional, no fixed order; the final leaf is always a sop.

| SOP | When to use |
| --- | --- |
| spawn-agent | Spawn a customized CC subagent with full MCP tool access. Used by SOPs that declare execution: subagent. |

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