Top Agent Skills

Manage notes, bookmarks, and notebooks using the nb CLI. Create, list, search, and organize notes across multiple notebooks with Git-backed versioning.

Analyzes raw genomic data (FASTQ/VCF) to generate non-medical wellness, longevity, and pharmacogenomic optimization protocols while keeping DNA processing local and private.

Discover, inspect, and call paid API endpoints using the x402 payment protocol, with automatic USDC payments on Base.

Retrieve fundraising data from Pilt, including investor matches, campaign statistics, outreach events, and deck analysis, using a personal API key.

Publishes text, markdown, or files to nosi.pub and returns a shareable URL.

Continues deep iteration on an existing planning document: detects explicit file-loading intent, provides status summaries, and supports on-demand in-depth exploration.

Creates, reads, edits, and converts PowerPoint presentations, including extracting text, generating slide images, and applying design guidance.

Runs time series machine learning tasks—classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search—using the scikit-learn compatible aeon toolkit.

Scales pandas and NumPy workflows to datasets larger than memory using parallel and distributed computing, with support for dataframes, arrays, bags, and custom task graphs.

Queries 20+ bioinformatics databases from the command line or Python for gene info, sequences, BLAST/BLAT, protein structures, viral data, and expression metrics.

Build, fit, validate, and compare Bayesian models using PyMC, including hierarchical models, MCMC sampling, variational inference, posterior predictive checks, and model comparison.

Runs a six-phase security audit covering attack-surface mapping, STRIDE/PASTA threat modeling, technical checklists, red/blue team exercises, and a final verdict, plus incident-response and monitoring guidance.

Analyzes marketing pages and forms to identify conversion barriers and provides prioritized, actionable recommendations for improving conversion rates.

Provides jurisdiction-specific legal context and contract scaffolding for the US, EU, and Canada, grounding agents in verified government references to reduce legal hallucinations.

Guides test-first development with vertical slices, writing one behavior test at a time and refactoring only when green.

Runs an autonomous optimization loop that iteratively improves an artifact against an objective and evaluator using Hypothesis Tree Refinement, with subagent executors in isolated git worktrees.

Solves single- and multi-objective optimization problems with NSGA-II/III, MOEA/D, and other evolutionary algorithms, including constraint handling, Pareto front analysis, and benchmark problems.

Read, write, and analyze genomic datasets including SAM/BAM/CRAM alignments, VCF/BCF variants, and FASTA/FASTQ sequences using a Pythonic interface to htslib.

Access AI-ready drug discovery datasets, benchmarks, and molecular oracles from Therapeutics Data Commons for therapeutic machine learning and pharmacological prediction.

Run cloud-native molecular modeling and drug-design workflows via a Python API, covering pKa prediction, docking, conformer and tautomer ensembles, molecular dynamics, and related small-molecule or protein tasks without local HPC infrastructure.

Build discrete-event simulations of systems with processes, queues, resources, and time-based events using the SimPy framework in Python.

Provides guidance for using SymPy for exact symbolic mathematics in Python, covering algebra, calculus, equation solving, linear algebra, physics, and code generation.

Applies curated color palettes and font pairings to style artifacts such as slide decks, docs, and landing pages, with 10 preset themes and the ability to generate custom themes on demand.

Trains machine learning models on genomic interval data from BED files, including region embeddings, single-cell ATAC-seq analysis, and consensus peak building.

Numerical computing with MATLAB and GNU Octave for matrix operations, data analysis, visualization, and scientific computing, including script execution and syntax guidance.

Loads and processes whole-slide pathology images, builds spatial graphs, trains deep learning models, and analyzes multiplexed immunofluorescence data across 160+ slide formats.

Build, optimize, and execute quantum circuits on IBM Quantum hardware or local simulators using Qiskit, including transpilation, primitives, and algorithm libraries.

Analyze RNA velocity in single-cell RNA-seq data with scVelo, estimating cell state transitions from unspliced/spliced mRNA dynamics, inferring trajectory directions, computing latent time, and identifying driver genes.

Manages annotated data matrices for single-cell genomics, covering creation, I/O, concatenation, and manipulation of AnnData objects in h5ad and zarr formats.

Provides guidance on using the Astropy library for astronomy and astrophysics workflows, including units, coordinates, FITS I/O, tables, time, WCS, and cosmology.

Manages biological datasets and models with LaminDB, covering setup, artifact registration, querying, lineage tracking, validation, ontology annotation, collections, branches, storage, and workflow integrations.

Process and analyze mass spectrometry data with the Matchms Python library, including importing spectra, filtering peaks, calculating similarity scores, and building reproducible analytical workflows.

Filters and prioritizes compound libraries in drug discovery using drug-likeness rules, structural alerts, complexity metrics, and a query language.

Query the Precision Medicine Knowledge Graph (PrimeKG) for multiscale biological data including genes, drugs, diseases, phenotypes, and more.

Read, write, and modify DICOM medical imaging files, including pixel data extraction, anonymization, format conversion, and compression handling.

Create publication-quality statistical graphics in Python with seaborn, covering relational, distribution, and categorical plots with pandas integration.

Guides users through a structured three-stage workflow for co-authoring documents, from context gathering to reader testing.

Guides distinctive, intentional visual design for new or existing UI, covering aesthetic direction, typography, and avoiding templated defaults.

Optimize content for AI search and LLM citations across AI Overviews, ChatGPT, Perplexity, Claude, Gemini, and similar systems. Use when improving AI visibility, answer engine optimization, or citation readiness.

Defines, validates, runs, resumes, and audits repo-local multi-step automations using the `asc workflow` CLI and `.asc/workflow.json`, including step outputs and safe release/TestFlight workflows.

Submits or updates a Wall of Apps entry in the App-Store-Connect-CLI repository using the `asc apps wall submit` command, with dry-run preview and confirmation.

Build, archive, export, upload, and manage Xcode version/build numbers with the current asc xcode helpers before App Store Connect upload or submission. Use when creating an IPA or PKG for upload.

Syncs App Store metadata with App Store Connect using the canonical asc metadata workflow, including pull, validate, preview, and apply steps for app-info and version localization fields.

Creates and renews iOS/macOS signing assets—bundle IDs, capabilities, certificates, and provisioning profiles—via the App Store Connect CLI, including encrypted git-backed team sync.

Automates translating and syncing App Store metadata (description, keywords, what's new, subtitle) to multiple locales using LLM translation and the asc CLI.

Resize and validate App Store screenshots using current asc size data and macOS sips, preparing them for App Store Connect submission.

Validates App Store submission readiness, submits prepared versions, and monitors review status using current asc commands.

Designs an edit blueprint and uncertainty register for video projects, following a narrative loop and schema constraints.

Exports a timeline.json as a Premiere Pro editor packet, including FCP7 XML, captions, and media, with verification steps.

Compiles a video editing timeline from blueprint and candidate files, generating timeline and preview manifests, with optional review patch application.

Orchestrates a full software development pipeline by sequentially loading and executing seven role-specific skills (BA, TechLead, PM, BE Dev, FE Dev, Tester, QA/QC), with configurable project levels and gate checks.

Runs a structured bug-fix pipeline that scouts, diagnoses, fixes, reviews, and finalizes code changes with optional quality re-verification.

Guides a structured planning pipeline for coding tasks, including scope detection, research, plan creation, and review.

Runs and writes tests, verifies behavior, and orchestrates two-pass TDD across scoped modes, blocking on quality gates and never editing production code.

Generates 12 detailed plan files from a project spec, one per SRS section, with FR/NFR numbering and a summary table.

Analyzes requirements and produces four artifact files: requirements, user stories, acceptance criteria, and business rules, with optional SRS workflow integration.

Generates frontend source code and a PR description from BA, TechLead, PM, and BE artifacts, following a level-based implementation plan.

Scans the projects/ directory and reports the pipeline phase completion status for each Virtual Team project.

Derives a comprehensive test plan and writes unit, integration, and end-to-end test cases from user stories and acceptance criteria, flagging issues in prior artifacts and declaring UAT readiness.

Audits code quality against a shared contract, returning structured findings without modifying code. Supports gate, audit, diff, changed, and verify modes.