AI & ML Agent Skills
AI & ML agent skills cover the machine-learning workflow itself: writing and evaluating prompts, building RAG pipelines, running evals, and wiring up model APIs. Each one is a SKILL.md file your agent loads on demand, so the know-how travels across Claude Code, Cursor, and 60+ agents.
AI & ML
5,020 skills
alterlab-ieu Alterlab Chai
Predict biomolecular complexes with Chai-1, an open AlphaFold3-style model that folds multi-entity assemblies (proteins, ligands, nucleic acids) from a single typed FASTA — strong on antibody–antigen and protein–ligand complexes, with optional MSA and restraint inputs. Use when predicting an antibody–antigen complex, folding a mixed protein/ligand/nucleic-acid assembly described in one FASTA, or generating a complex with experimental restraints. For binding-affinity prediction or a ligand-focused co-fold prefer alterlab-boltz; for protein-only or protein–protein folding prefer alterlab-alphafold; to dock into a fixed receptor prefer alterlab-diffdock. Part of the AlterLab Academic Skills suite.
60 · bundle
alterlab-ieu Alterlab Borzoi
Predict genome-wide functional genomics tracks from DNA sequence with Borzoi (Linder 2025) — a sequence-to-function model outputting RNA-seq, CAGE, ATAC, and ChIP coverage across long context, used to score non-coding and regulatory variant effects. Use when predicting functional tracks from a DNA sequence, scoring a non-coding/regulatory variant's effect on expression or chromatin, or doing in-silico mutagenesis of a locus. To LOOK UP a variant's population frequency prefer alterlab-gnomad; for its clinical significance prefer alterlab-clinvar; for protein-structure effects prefer alterlab-alphafold; for single-cell foundation models prefer alterlab-scgpt. Part of the AlterLab Academic Skills suite.
60 · bundle
alterlab-ieu Alterlab Histolab
Extract and preprocess tiles from whole-slide images (WSI) with histolab — OpenSlide-backed slide loading, tissue detection and masks, Random/Grid/Score tile extraction, and image/morphological filters for H&E preprocessing. Use when the user needs lightweight WSI slide preprocessing — building tile datasets for ML training, tissue segmentation, or quick tile-based inspection of histopathology slides. For end-to-end computational-pathology, deep-learning model training, nucleus segmentation, or multiplexed/spatial-proteomics (CODEX, Vectra) pipelines prefer alterlab-pathml instead. Part of the AlterLab Academic Skills suite.
60 · bundle
alterlab-ieu Alterlab Molfeat
Featurizes molecules for machine learning with molfeat (100+ featurizers) — ECFP/MACCS/MAP4 fingerprints, RDKit and Mordred physicochemical descriptors, and pretrained embeddings (ChemBERTa, ChemGPT, GIN) exposed as scikit-learn transformers that convert SMILES into feature vectors. Use when turning molecules into ML-ready feature matrices for QSAR/QSPR or virtual screening, or benchmarking fingerprint against descriptor and embedding representations; for training models and MoleculeNet benchmarks on those features prefer alterlab-deepchem, and for low-level fingerprint or descriptor primitives prefer alterlab-rdkit. Part of the AlterLab Academic Skills suite.
60 · bundle
zhixuli0406 Duduclaw
Use DuDuClaw — a self-hosted AI-employee platform — for cross-session memory, team-shared wiki knowledge, task boards, and messaging humans over LINE/Telegram/Discord/Slack. Applies when the user mentions DuDuClaw, asks their agent to remember things durably, or wants to reach people on messaging channels from an agent.
45
zhixuli0406 PDF
Read and create PDF documents — extract text (and per-page text) from a PDF to JSON/markdown, and render markdown/plain text into a new PDF.
45 · bundle
zhixuli0406 DOCX
Read, create, and convert Microsoft Word (.docx) documents — extract text and tables, build reports from markdown/JSON, and export to PDF.
45 · bundle
zhixuli0406 Duduclaw Platform
Use the DuDuClaw MCP tools (persistent memory, shared wiki, task board, channel messaging) when the user asks to remember something across sessions, share knowledge with their team's AI employees, manage tasks, or message someone on LINE/Telegram/Discord/Slack. Requires a running DuDuClaw gateway (`npx duduclaw onboard` to set up).
45
zhouziyue233 Panel Data
Econometrics skill for panel data models. Activates when the user asks about: "panel data", "fixed effects", "random effects", "Hausman test", "within estimator", "between estimator", "two-way fixed effects", "clustered standard errors panel", "FE model", "RE model", "pooled OLS", "unobserved heterogeneity", "panel regression", "first difference estimator", "entity fixed effects", "time fixed effects", "面板数据", "固定效应", "随机效应", "豪斯曼检验", "双向固定效应", "面板回归", "个体效应", "时间效应", "一阶差分"
7 · bundle
pablolion Bmad Agent QA
QA engineer for test automation and coverage. Use when the user asks to talk to Quinn or requests the QA engineer.
12
pablolion Bmad Agent Sm
Scrum master for sprint planning and story preparation. Use when the user asks to talk to Bob or requests the scrum master.
12
pablolion Bmad Agent Tech Writer
Technical documentation specialist and knowledge curator. Use when the user asks to talk to Paige or requests the tech writer.
12 · bundle
pablolion Bmad Agent UX Designer
UX designer and UI specialist. Use when the user asks to talk to Sally or requests the UX designer.
12
pablolion Bmad Advanced Elicitation
Push the LLM to reconsider, refine, and improve its recent output. Use when user asks for deeper critique or mentions a known deeper critique method, e.g. socratic, first principles, pre-mortem, red team.
12 · bundle
pablolion Bmad Agent Quick Flow Solo Dev
Elite full-stack developer for rapid spec and implementation. Use when the user asks to talk to Barry or requests the quick flow solo dev.
12
pablolion Bmad Cis Agent Brainstorming Coach
Elite brainstorming specialist for facilitated ideation sessions. Use when the user asks to talk to Carson or requests the Brainstorming Specialist.
12
pablolion Bmad Cis Agent Presentation Master
Visual communication and presentation expert for slide decks, pitch decks, and visual storytelling. Use when the user asks to talk to Caravaggio or requests the Presentation Expert.
12
pablolion Bmad Cis Agent Design Thinking Coach
Design thinking maestro for human-centered design processes. Use when the user asks to talk to Maya or requests the Design Thinking Maestro.
12
chrismccoy Threat Model
STRIDE Threat Model
2 · bundle
chrismccoy Prompt Summary
Prompt Summary - rigorous, review-ready analysis of any AI prompt
2
bouclem LLM
Large Language Model development, training, fine-tuning, and deployment best practices.
7
bouclem Mlops
MLflow, model versioning, experiment tracking, model registry, and production ML systems
7 · bundle
bouclem Tokenwise
Measurement-driven model router for Claude Code. Routes Haiku/Sonnet/Opus per task class, logs every routed task with real $ numbers, and A/B tests cheaper tiers before you trust the savings.
7
bouclem Statsmodels
Statsmodels is Python's premier library for statistical modeling, providing tools for estimation, inference, and diagnostics across a wide range of statistical methods.
7
bouclem Skill Audit
Pre-install security scanner for AI agent skills. 7.5% of 14,706 skills are malicious. Audit before you trust.
7
bouclem AI Engineer
Build production-ready LLM applications, advanced RAG systems, and intelligent agents. Implements vector search, multimodal AI, agent orchestration, and enterprise AI integrations.
7
bouclem Skill Writer
Create and improve agent skills following the Agent Skills specification. Use when asked to create, write, or update skills.
7 · bundle
bouclem Scikit Learn
Machine learning in Python with scikit-learn. Use for classification, regression, clustering, model evaluation, and ML pipelines.
7
bouclem Skill Scanner
Scan agent skills for security issues before adoption. Detects prompt injection, malicious code, excessive permissions, secret exposure, and supply chain risks.
7
bouclem RAG Engineer
Expert in building Retrieval-Augmented Generation systems. Masters embedding models, vector databases, chunking strategies, and retrieval optimization for LLM applications.
7
bouclem Skill Improver
Iteratively improve a Claude Code skill using the skill-reviewer agent until it meets quality standards. Use when improving a skill with multiple quality issues, iterating on a new skill until it meets standards, or automated fix-review cycles instead of manual editing.
7
winbda Dcf Model
Build discounted cash flow models for company valuation. TRIGGERS - Use when user needs help with dcf-model related tasks.
3
winbda Logic Model
Build logic models linking activities to impact. TRIGGERS - Use when user needs help with logic-model related tasks.
3
vimalinx Biomni
Use when working from the local Biomni repository to run agent-style biomedical tasks or inspect Biomni's biomedical tool modules and examples.
0
nous-hermeshub Board
Read, write, and browse the AgentHub message board for agent coordination. Use when the user runs /hub:board or asks to post, read, or inspect coordination messages between competing AgentHub agents.
1
nous-hermeshub Seaborn
Seaborn is a Python visualization library for creating publication-quality statistical graphics. Use this skill for dataset-oriented plotting, multivariate analysis, automatic statistical estimation, and complex multi-panel figures with minimal code.
1
Frequently asked questions
What are AI & ML agent skills?
AI & ML agent skills cover the machine-learning workflow itself: writing and evaluating prompts, building RAG pipelines, running evals, and wiring up model APIs. Each one is a SKILL.md file your agent loads on demand, so the know-how travels across Claude Code, Cursor, and 60+ agents.
Which AI & ML skills are most installed?
Popular AI & ML skills on SkillMD right now include alterlab-borzoi, threat-model, prompt-summary. Rankings shift as installs change; sort this page by "Most downloaded" for the live list.
Do AI & ML skills work with Claude Code and Cursor?
Yes. Every skill here ships as a SKILL.md file, an open format that works in Claude Code, Claude.ai, Cursor, Codex, Windsurf, and 60+ other agents. Install one with npx skillmds add <owner>/<name>, or copy the file into your agent's skills directory.