ClawBio@ClawBio
by @gabrielmoreira · plugin · 39 skills
ClawBio@ClawBio from gabrielmoreira/agent-skills-mirror.
Install the whole plugin (CLI)
npx skillmds add gabrielmoreira/dnasp
npx skillmds add gabrielmoreira/clinpgx
npx skillmds add gabrielmoreira/labstep
npx skillmds add gabrielmoreira/nutrigx
npx skillmds add gabrielmoreira/wgs-prs
npx skillmds add gabrielmoreira/bgpt-mcp
npx skillmds add gabrielmoreira/fastreer
npx skillmds add gabrielmoreira/flow-bio
npx skillmds add gabrielmoreira/gwas-prs
npx skillmds add gabrielmoreira/soul2dna
npx skillmds add gabrielmoreira/bioqc-mcp
npx skillmds add gabrielmoreira/gi-splice
npx skillmds add gabrielmoreira/rnaseq-de
npx skillmds add gabrielmoreira/de-summary
npx skillmds add gabrielmoreira/drug-photo
npx skillmds add gabrielmoreira/hla-typing
npx skillmds add gabrielmoreira/polars-bio
npx skillmds add gabrielmoreira/gi-enhancer
npx skillmds add gabrielmoreira/gi-promoter
npx skillmds add gabrielmoreira/gwas-lookup
npx skillmds add gabrielmoreira/fine-mapping
npx skillmds add gabrielmoreira/genome-match
npx skillmds add gabrielmoreira/gi-chromatin
npx skillmds add gabrielmoreira/just-prs-mcp
npx skillmds add gabrielmoreira/protocols-io
npx skillmds add gabrielmoreira/recombinator
npx skillmds add gabrielmoreira/seq-wrangler
npx skillmds add gabrielmoreira/analyze-fasta
npx skillmds add gabrielmoreira/equity-scorer
npx skillmds add gabrielmoreira/galaxy-bridge
npx skillmds add gabrielmoreira/gi-annotation
npx skillmds add gabrielmoreira/gi-expression
npx skillmds add gabrielmoreira/gwas-pipeline
npx skillmds add gabrielmoreira/ncbi-datasets
npx skillmds add gabrielmoreira/proteomics-de
npx skillmds add gabrielmoreira/skill-builder
npx skillmds add gabrielmoreira/ukb-navigator
npx skillmds add gabrielmoreira/vcf-annotator
npx skillmds add gabrielmoreira/busco-assessorSkills in this plugin
- ▌ dnasp · gabrielmoreira bundleReimplements DnaSP 6 for population genetics analysis of aligned DNA sequences, including nucleotide diversity, haplotype statistics, neutrality tests, linkage disequilibrium, recombination, mismatch distribution, InDel polymorphism, between-population divergence, outgroup-based tests, HKA test, McDonald-Kreitman.
- ▌ clinpgx · gabrielmoreira bundleQuery the ClinPGx API for pharmacogenomic gene-drug data, clinical annotations, CPIC guidelines, and FDA drug labels.
- ▌ labstep · gabrielmoreira bundleQueries and displays Labstep electronic lab notebook data — experiments, protocols, resources, and inventory — via labstepPy, with an offline demo mode using synthetic biology data.
- ▌ nutrigx · gabrielmoreira bundleGenerates a personalised nutrition report from consumer genetic data (23andMe, AncestryDNA, VCF) by interrogating nutritionally-relevant SNPs and producing actionable dietary guidance, all computed locally.
- ▌ wgs-prs · gabrielmoreira bundleTakes raw whole-genome sequencing FASTQ files or a pre-existing VCF through variant calling, quality control, and polygenic risk score computation using the PGS Catalog.
- ▌ bgpt-mcp · gabrielmoreira bundleSearch scientific papers via the BGPT MCP server and retrieve structured experimental data — methods, results, conclusions, quality scores, and 25+ metadata fields per paper.
- ▌ fastreer · gabrielmoreira bundleComputes phylogenetic distance matrices and trees from genomic VCF or FASTA data using the fastreeR hybrid Java/Python toolkit.
- ▌ flow-bio · gabrielmoreira bundleAuthenticate, browse pipelines, samples, and projects, upload data, launch pipeline executions, and check run status on any Flow.bio instance via CLI.
- ▌ gwas-prs · gabrielmoreira bundleCalculate polygenic risk scores from direct-to-consumer genetic data using published scoring files from the PGS Catalog and contextualize results against population reference distributions.
- ▌ soul2dna · gabrielmoreira bundleCompile SOUL.md character profiles into synthetic diploid genomes (.genome.json) via trait-to-allele mapping.
- ▌ bioqc-mcp · gabrielmoreira bundleAutomates sequencing quality control by running FastQC and MultiQC, extracting quality metrics, and generating publication-ready visualizations via a CLI or MCP stdio server.
- ▌ gi-splice · gabrielmoreira bundleDetect splice donor and acceptor sites in DNA sequences using the Genomic Intelligence G0 BigBird transformer, via the hosted /v1/tasks/splice/predict API. Returns per-position site probabilities and called sites.
- ▌ rnaseq-de · gabrielmoreira bundlePerforms differential expression analysis on bulk RNA-seq or pseudo-bulk count matrices with QC, PCA, and contrast testing.
- ▌ de-summary · gabrielmoreiraTakes pre-computed differential expression results from DESeq2, edgeR, limma, or PyDESeq2 and produces a structured, publication-ready summary with ranked gene lists, biological themes, and key observations.
- ▌ drug-photo · gabrielmoreira bundleIdentifies a medication from a photo and generates a genotype-informed dosage card using CPIC guidelines and real 23andMe data.
- ▌ hla-typing · gabrielmoreira bundlePerforms HLA allele genotyping from WGS/WES VCF data, producing a structured markdown report and machine-readable JSON results.
- ▌ polars-bio · gabrielmoreira bundlePerform fast genomic interval operations (overlap, nearest, merge, coverage, cluster, complement, subtract, count-overlaps), multi-format bioinformatics I/O, DataFusion SQL, and pileup on Polars DataFrames via the polars-bio library, serving as a scalable alternative to bioframe and bedtools.
- ▌ gi-enhancer · gabrielmoreira bundlePredicts enhancer activity in DNA sequences using the hosted Genomic Intelligence G0 DeepSTARR model, returning per-window activity scores.
- ▌ gi-promoter · gabrielmoreira bundleDetect promoter regions in DNA sequences by calling the Genomic Intelligence G0 transformer (GENA-LM BERT Large) hosted API. Returns per-window promoter probabilities and called regions as a report and JSON, from a single FASTA input.
- ▌ gwas-lookup · gabrielmoreira bundleQueries 9 genomic databases in parallel for a given rsID, returning unified GWAS, PheWAS, eQTL, and fine-mapping reports.
- ▌ fine-mapping · gabrielmoreira bundleStatistical fine-mapping of GWAS loci using SuSiE, SuSiE-inf, and Approximate Bayes Factors to identify credible sets and posterior inclusion probabilities (PIPs) for causal variant discovery. SuSiE-inf adds an infinitesimal polygenic component for improved calibration at well-powered loci.
- ▌ genome-match · gabrielmoreira bundleScores genetic compatibility between all male-female pairings in a Genomebook generation, ranking optimal mating pairs based on heterozygosity, trait complementarity, and disease risk.
- ▌ gi-chromatin · gabrielmoreira bundlePredicts chromatin state across 919 tracks (histone marks, DNase, TF binding) for DNA sequences via the hosted Genomic Intelligence API, producing a report and JSON results.
- ▌ just-prs-mcp · gabrielmoreira bundleComputes evidence-aware polygenic risk scores from local VCF or WGS files using the just-prs engine and a pinned local MCP server, with honest interpretation and model comparison.
- ▌ protocols-io · gabrielmoreira bundleSearch, browse, and retrieve scientific protocols from protocols.io via REST API, including private protocols with client token authentication.
- ▌ recombinator · gabrielmoreira bundleSimulates meiotic recombination to produce offspring genomes from parent pairs, modeling Mendelian segregation, de novo mutation, sex determination, trait inference, and clinical evaluation against a disease registry.
- ▌ seq-wrangler · gabrielmoreira bundleRuns NGS read QC, alignment, and BAM processing, wrapping FastQC, BWA/Bowtie2/Minimap2, SAMtools, and MultiQC for automated read-to-BAM workflows.
- ▌ analyze-fasta · gabrielmoreira bundleAnalyze a single FASTA file (nucleotide or protein), compute sequence-level metrics (GC, ORFs, MW, pI, GRAVY, secondary-structure fractions) with Biopython, and write a Markdown report plus structured JSON for downstream chaining.
- ▌ equity-scorer · gabrielmoreira bundleComputes HEIM diversity and equity metrics from VCF or ancestry data, generating heterozygosity, FST, PCA plots, and a composite HEIM Equity Score with markdown reports.
- ▌ galaxy-bridge · gabrielmoreira bundleDiscovers and executes bioinformatics tools from the Galaxy ecosystem via natural language, with multi-signal scoring, workflow templates, and reproducibility bundles.
- ▌ gi-annotation · gabrielmoreira bundlePredicts gene and transcript structure from a DNA sequence using the hosted Genomic Intelligence API, producing a report and JSON output.
- ▌ gi-expression · gabrielmoreira bundlePredicts tissue or cell-type gene expression (log TPM and TPM) from a TSS-centered DNA sequence using the hosted Genomic Intelligence G0 Expression model, conditioned on a free-text cell-type description.
- ▌ gwas-pipeline · gabrielmoreira bundleAutomates genome-wide association studies from genotype files to publication-ready results, running PLINK2 QC and REGENIE regression with Manhattan and QQ plots.
- ▌ ncbi-datasets · gabrielmoreira bundleDownloads genomes, genes, virus sequences, and taxonomy data from NCBI using the datasets and dataformat CLI tools.
- ▌ proteomics-de · gabrielmoreira bundlePerforms differential expression analysis on label-free quantitative (LFQ) proteomics data from MaxQuant and DIA-NN outputs, including preprocessing, imputation, statistical testing, and visualization.
- ▌ skill-builder · gabrielmoreira bundleScaffolds a new ClawBio skill from a JSON/YAML spec or interactively, generating SKILL.md, Python skeleton, tests, and updating the catalog.
- ▌ ukb-navigator · gabrielmoreira bundleSearches UK Biobank's 12,000+ data fields and publications by natural language query, returning ranked field IDs and descriptions for research questions.
- ▌ vcf-annotator · gabrielmoreira bundleAnnotates VCF variants using Ensembl VEP, ClinVar, and gnomAD, ranks them by predicted impact, and generates a reproducible report.
- ▌ busco-assessor · gabrielmoreira bundleAssesses genome, transcriptome, and protein completeness with BUSCO v6, automatically resolving the correct lineage from an organism description and generating reproducible reports.