Results for “h5ad”

Single-cell RNA-seq analysis. Load .h5ad/10X data, QC, normalization, PCA/UMAP/t-SNE, Leiden clustering, marker genes, cell type annotation, trajectory, for scRNA-seq analysis.

Análise de RNA-seq de célula única. Carregue dados .h5ad/10X, QC, normalização, PCA/UMAP/t-SNE, clustering Leiden, genes marcadores, anotação de tipo celular, trajetória, para análise de scRNA-seq.

Detect process injection techniques (T1055) including CreateRemoteThread, process hollowing, and DLL injection via Sysmon Event IDs 8 and 10 and EDR process telemetry.

A complete tour of the intelli-verse-x 5-layer stack — Leantime/GitHub at the top, Beads/Bernstein/Claude-Squad in the middle, Gas Town as the multi-project fabric, and LiteLLM/Infisical/Langfuse/n8n/GH-Actions underneath. Use whenever the user asks "what does X service do", "where does Y data live", "how do I get to Z", or you need to understand which tool to reach for. This is the architecture map.

Implements a simplified version of the Signal Protocol's Double Ratchet algorithm using X25519, HKDF, and AES-256-GCM for end-to-end encrypted messaging.

Create, read, manipulate, and store annotated data matrices using the AnnData Python package, designed for single-cell genomics and general-purpose annotated data workflows.

Access the Human Metabolome Database (HMDB, 220K+ metabolites), searching by name, HMDB ID, or structure to retrieve chemical properties, biomarker data, NMR/MS reference spectra, and associated pathways. Use when identifying a human metabolite, looking up its biomarker or disease associations, matching NMR/MS spectra, or running metabolomics annotation. Part of the AlterLab Academic Skills suite.

Restructure any response for an ADHD brain — TL;DR first, ELI16 clarity, short punchy steps, one clear next action, zero walls of text. Use this skill whenever the user says "elihadhd", "adhd mode", "tldr", "eli16", "eli5", "too long", "overwhelmed", "shorter", "just tell me what to do", "break this down", "snap it", "gauntlet", or shows signs of overwhelm (e.g. "wait what", "I'm lost", "too much"). Also use it when the user asks for the simple version, the quick version, or the punchy version of anything — explanations, plans, debugging help, docs, decisions. When in doubt about whether a response is too heavy, use this skill.

heath-no-fluff

Suggests testing HPA axis functionality before and after starting GH replacement in patients not receiving glucocorticoid replacement with apparently normal pituitary-adrenal function. Triggers include initiating GH replacement in a GHD patient who is not on glucocorticoids and has normal adrenal function.

Select oral and injectable glucose-lowering agents for a newly diagnosed patient with type 2 diabetes using a compelling-indication hierarchy (heart failure → ASCVD → DKD → obesity) followed by glucose-pattern matching. Incorporates modern GLP-1 receptor agonists — Ozempic (semaglutide SC, T2D), Mounjaro (tirzepatide), and Wegovy/Noveltreat (semaglutide 2.4 mg, obesity). Use when a clinician asks "what drug to start for newly diagnosed T2D", "which OAD to use", "first-line diabetes medication", "SGLT2i vs GLP-1 in new T2D", or presents a newly diagnosed T2D patient needing a personalised medication plan.

Use when hashing FASTA records and comparing ordered versus order-insensitive sequence digests instead of taking a single whole-file MD5.

Data structure for annotated matrices in single-cell analysis. Use when working with .h5ad files or integrating with the scverse ecosystem. This is the data format skill—for analysis workflows use scanpy; for probabilistic models use scvi-tools; for population-scale queries use cellxgene-census.

Esta habilidade deve ser usada ao trabalhar com matrizes de dados anotados em Python, particularmente para análise de genômica de célula única, gerenciamento de medições experimentais com metadados ou manipulação de datasets biológicos em larga escala. Use quando as tarefas envolvam objetos AnnData, arquivos h5ad, dados de RNA-seq de célula única ou integração com ferramentas scanpy/scverse.