Results for “pcre2”

Imported skill reference from anthropic

Determines if PAC/PRA ratio and PAC levels indicate positive or provisionally positive screening for primary aldosteronism. Triggered when a clinician has PAC and PRA results and asks “Is this screening test positive for PA?” or needs to interpret borderline results.

Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.

Run differential gene expression analysis on bulk RNA-seq count matrices with PyDESeq2, the Python port of DESeq2 — size-factor normalization, dispersion estimation, Wald tests, FDR (Benjamini-Hochberg) correction, and volcano/MA plots. Use when identifying differentially expressed genes between conditions from raw bulk RNA-seq counts. Part of the AlterLab Academic Skills suite.

Provides a command-line workflow for binary analysis with radare2, covering reconnaissance, disassembly, function analysis, string and import inspection, patching, binary diffing, and r2pipe scripting across PE, ELF, Mach-O, DEX, and WASM formats.

Perform differential gene expression analysis for bulk RNA-seq data using PyDESeq2, supporting formulaic designs, Wald tests, FDR correction, LFC shrinkage, and result visualization.

Recommends ACE inhibitors, ARBs, or calcium channel blockers as first-line hypertension therapy rather than β‑adrenergic blockers in obese patients with type 2 diabetes. Triggers include when a clinician asks, 'What antihypertensive should I start for this obese patient with T2DM to avoid weight gain?' or 'Should I avoid β‑blockers in this patient with diabetes and hypertension?'

Guides end-to-end testing of frontend applications using Playwright or Cypress, covering multi-page user flows in real browsers, API mocking, and CI integration.

Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.

Citrea: first ZK-rollup on Bitcoin (mainnet 27 Jan 2026), zkEVM, BitVM2 trustless bridge, ctUSD stablecoin, native BTC lending. USE WHEN: building zkEVM apps on Bitcoin, integrating with Citrea, evaluating ZK rollups vs sidechains.

MaxFuse parameter tuning for datasets with large protein:RNA cell ratios (>100:1)

Prepare PRINCE2 Directing a Project gate briefs for project board decisions, including initiation authorization, stage authorization, exception decisions, and closure authorization.

Run PRINCE2 Controlling a Stage: work package tracking, highlight reports, risk and issue control, tolerance checks, change handling, and corrective action planning.

Evaluates likelihood of primary aldosteronism by measuring plasma aldosterone suppression after oral captopril; normal suppression ≥30% makes PA unlikely, while lack of suppression with persistently suppressed plasma renin activity suggests PA. Use when assessing captopril challenge test (CCT) results for PA diagnosis in patients with positive aldosterone-to-renin ratio.

ORCA v2.0 — Gen-2 Striker with momentum event quality confirmation. FIRST_JUMP detection enhanced with Tier 2 momentum events and TCS trader quality tags. Stalker permanently removed. DSL exit managed by plugin runtime via runtime.yaml.

Performance Profiler

Systematically deobfuscate multi-layer PowerShell malware using AST analysis, dynamic tracing, and tools like PSDecode and PowerDecode to reveal hidden payloads and C2 infrastructure.

Harness E2E

Diagnose frame-rate bottlenecks (CPU vs GPU bound FIRST), control Unreal Insights traces, sample live frame times, and annotate performance captures. Use when FPS is low/bad, the game is slow, or you need to find what is limiting the frame rate.

Interprets the aldosterone-to-renin ratio using active renin concentration (ARC) to screen for primary aldosteronism. Triggered when a clinician has PAC and ARC results and asks 'How do I interpret this ARR using active renin concentration?'

Generate, review, fix, and migrate Playwright end-to-end tests with templates, CI integration, and optional TestRail/BrowserStack sync.

PR 代码评审，检查安全漏洞、Bug 和代码质量。

Deterministic pixel art upscaling using EPX/Scale2x, hq2x/hq4x, and xBR algorithms that add valid sub-pixels through pattern recognition. Activate on 'pixel art scaling', 'EPX', 'Scale2x', 'hq2x', 'hq4x', 'xBR', 'retro game upscaling'. NOT for AI/ML upscaling, photo enlargement, or simple nearest-neighbor.

Strata by Alpen Labs: ZK rollup on Bitcoin, BitVM-based bridge, EVM-compatible execution. Emerging Bitcoin L2 in 2025-2026. USE WHEN: evaluating Strata for deployment, comparing with Citrea.

Legal-specific Argument Ranking Engine. Hodnotí právní argumenty 17-sloupcovým scoringem (síla, bezpečnost, dopad, riziko + 10 legal-specific kritérií: Compliance s novelou 2026, Evidence backing, Time-sensitivity, per-document mapping, R-static/R-reversal split, Tom-weight bonus, C-XX/M-XX/N-XX/D-XX integrace). Output: priorizovaný seznam argumentů s kategoriemi CORE/SUPPORT/CONTEXT/EXCLUDED/SUMMARY a per-document bundles (PR/§909/40_06/195). Použití: pre-prioritizace argumentů před F11.x review, Phase 2 Verify input, DÁVKA 3, výživné L04, AT podání. VŽDY použij tento skill, když Tom (nebo legal/strat) zmíní: /lare, lare, argument ranking, ARE matrix, score arguments, prioritize arguments, argument bundle, CORE/SUPPORT/CONTEXT/EXCLUDED, ARE_F11, LARE_F11, legal argument evaluation, argument scoring, compliance scoring, Tom-weight.

Generates, reviews, fixes, and migrates Playwright end-to-end tests, with templates, agents, and integrations for TestRail and BrowserStack.