Results for “g-suite”

Provides the RDKit cheminformatics toolkit for low-level, fine-grained molecular primitives — SMILES/SDF parsing, descriptors (MW, LogP, TPSA), fingerprints, substructure/SMARTS search, 2D/3D coordinate generation, similarity, and reaction handling. Use when custom sanitization, specialized fingerprint or descriptor algorithms, reaction enumeration, or conformer generation demand direct API control; for a high-level pandas-friendly wrapper over RDKit prefer alterlab-datamol, and for turning molecules into ML feature vectors prefer alterlab-molfeat. Part of the AlterLab Academic Skills suite.

Creates, analyzes, and visualizes complex networks and graphs in Python with NetworkX. Use when working with network/graph data structures, analyzing relationships between entities, computing graph algorithms (shortest paths, centrality, clustering), detecting communities, generating synthetic networks, or visualizing topologies — applicable to social, biological, transportation, citation, and any pairwise-relationship networks. This is classical graph analytics, not deep learning — for training graph neural networks (GCN/message passing, node/edge/graph classification on Cora-style data) use alterlab-torch-geometric instead. Part of the AlterLab Academic Skills suite.

Prisma ORM for Node.js/TypeScript. Covers schema definition, migrations, and type-safe queries. Use when working with Prisma. USE WHEN: user mentions "prisma", "schema.prisma", "prisma migrate", "prisma generate", "prisma studio", "@prisma/client", asks about "how to define models in prisma", "prisma relations", "prisma transactions", "type-safe database queries" DO NOT USE FOR: raw SQL queries - use `database-query` MCP; Drizzle ORM - use `drizzle` skill; TypeORM - use `typeorm` skill; SQLAlchemy - use `sqlalchemy` skill

Access NCBI GEO (Gene Expression Omnibus) for gene expression and functional genomics data — search and download microarray and RNA-seq datasets by GSE, GSM, GPL, or GDS accession and retrieve SOFT, MINiML, and series matrix files. Use when locating public expression datasets, fetching processed expression matrices, downloading a study's supplementary files, or sourcing per-study transcriptomics data for differential-expression analysis. For raw FASTQ sequencing reads by SRA/ENA run accession use alterlab-ena; for reference tissue-expression baselines (median TPM across human tissues) use alterlab-gtex; for cancer cohort somatic mutations and copy-number use alterlab-cbioportal. Part of the AlterLab Academic Skills suite.

Structured data + RAG. NL2SQL hybrid patterns (text-to-SQL then execute vs embed rows), table embedding strategies (row-level, schema-level, hybrid), semantic layer integration (Cube, dbt metrics), LangChain SQLDatabaseChain, LlamaIndex PandasQueryEngine, safe SQL execution (read-only, sandboxed), schema-aware retrieval. Full PostgreSQL + pgvector hybrid code. USE WHEN: user mentions "tabular RAG", "NL2SQL", "text to SQL", "RAG on tables", "database RAG", "SQL RAG", "semantic layer", "structured data RAG" DO NOT USE FOR: unstructured doc RAG - use `rag-architecture`; metadata filtering only - use `self-querying-retriever`; KG retrieval - use `graph-rag`

Query cBioPortal via its keyless REST API for cancer genomics across TCGA, GENIE, MSK-IMPACT and hundreds of studies — somatic mutations, copy-number alterations (GISTIC), mRNA/protein expression, structural variants, and patient-level clinical/survival data. Use when asked how often a gene is mutated/amplified/deleted in a tumor type, to profile oncogenes or tumor suppressors across cancers (pan-cancer alteration frequency), to pull patient-level mutations joined to OS/clinical outcomes, or to validate a cancer target from cohort genomics. For germline variant pathogenicity use alterlab-clinvar; for mutational-signature (SBS) decomposition use alterlab-cosmic; for CRISPR/RNAi gene-dependency use alterlab-depmap; for aggregated target-disease evidence use alterlab-opentargets. Part of the AlterLab Academic Skills suite.