Plugins
2 plugins@alirezarezvani
Engineering
37 advanced engineering skills: agent designer, agent workflow designer, RAG architect, database designer + schema designer + SQL assistant, migration architect, observability designer, dependency auditor, changelog generator (with semantic version bumper and hotfix/rollback procedures), API design reviewer, API test suite builder, CI/CD pipeline builder, MCP server builder, skill security auditor
33 skills · plugin
@trailofbits
Trailmark
Builds multi-language source code graphs for security analysis: call graphs, attack surface mapping, blast radius, taint propagation, complexity hotspots, and entry point enumeration. Generates Mermaid diagrams (call graphs, class hierarchies, dependency maps, heatmaps). Compares code graph snapshots for structural diff and evolution analysis. Runs graph-informed mutation testing triage (genotoxic
10 skills · plugin
Results for “gene-dependency”
13 skills
qhjqhj00 depmap
Query the Cancer Dependency Map (DepMap) for CRISPR gene dependency scores, drug sensitivity data, and gene effect profiles to identify cancer-specific vulnerabilities, synthetic lethal interactions, and validate oncology drug targets.
3 · bundle
k-dense-ai depmap
Query the Cancer Dependency Map (DepMap) for cancer cell line gene dependency scores, drug sensitivity data, and gene effect profiles to identify cancer-specific vulnerabilities, synthetic lethal interactions, and validate oncology drug targets.
30.2k · bundle
More results
lingxling depmap
Query the Cancer Dependency Map (DepMap) for cancer cell line gene dependency scores (CRISPR Chronos), drug sensitivity data, and gene effect profiles. Use for identifying cancer-specific vulnerabilities, synthetic lethal interactions, and validating oncology drug targets.
253 · bundle
gabrielmoreira gi-annotation
Predicts gene and transcript structure from a DNA sequence using the hosted Genomic Intelligence API, producing a report and JSON output.
17 · bundle
gabrielmoreira recombinator
Simulates meiotic recombination to produce offspring genomes from parent pairs, modeling Mendelian segregation, de novo mutation, sex determination, trait inference, and clinical evaluation against a disease registry.
17 · bundle
k-dense-ai arboreto
Infer gene regulatory networks from gene expression data using scalable algorithms (GRNBoost2, GENIE3) with support for distributed computation.
30.2k · bundle
k-dense-ai onekgpd
Query the 1000 Genomes Project dataset at the individual participant level to find variants, carriers, and relatedness information.
30.2k · bundle
gabrielmoreira gwas-pipeline
Automates genome-wide association studies from genotype files to publication-ready results, running PLINK2 QC and REGENIE regression with Manhattan and QQ plots.
17 · bundle
k-dense-ai pathway-enrichment
Run pathway and gene-set enrichment analysis on gene lists or ranked gene data, then interpret the results. Covers over-representation analysis (ORA), Gene Set Enrichment Analysis (GSEA), and single-sample scoring using gseapy, g:Profiler, and Enrichr libraries.
30.2k · bundle
lingxling onekgpd
Queries the 1000 Genomes Project dataset (3,202 whole-genome-sequenced individuals, GRCh38) at the level of individual participants, returning variants, carriers, and relatedness with allele frequencies and annotations.
253 · bundle
gabrielmoreira gi-chromatin
Predicts chromatin state across 919 tracks (histone marks, DNase, TF binding) for DNA sequences via the hosted Genomic Intelligence API, producing a report and JSON results.
17 · bundle
alterlab-ieu alterlab-cbioportal
Query cBioPortal via its keyless REST API for cancer genomics across TCGA, GENIE, MSK-IMPACT and hundreds of studies — somatic mutations, copy-number alterations (GISTIC), mRNA/protein expression, structural variants, and patient-level clinical/survival data. Use when asked how often a gene is mutated/amplified/deleted in a tumor type, to profile oncogenes or tumor suppressors across cancers (pan-cancer alteration frequency), to pull patient-level mutations joined to OS/clinical outcomes, or to validate a cancer target from cohort genomics. For germline variant pathogenicity use alterlab-clinvar; for mutational-signature (SBS) decomposition use alterlab-cosmic; for CRISPR/RNAi gene-dependency use alterlab-depmap; for aggregated target-disease evidence use alterlab-opentargets. Part of the AlterLab Academic Skills suite.
60 · bundle
k-dense-ai bulk-rnaseq
Orchestrates a complete bulk RNA-seq differential-expression study from raw FASTQ reads through QC, alignment, quantification, differential expression, pathway enrichment, and publication figures.
30.2k · bundle