Results for “side-effects”

Initiates a 6‑month trial of DHEA replacement in women with primary adrenal insufficiency (PAI) who have persistent low libido, depressive symptoms, or low energy despite otherwise optimized glucocorticoid and mineralocorticoid therapy. If the patient does not report a sustained beneficial effect after 6 months, discontinue DHEA.

Cost-benefit analysis. Produces economic NPV and financial NPV side by side, with BCR, optimism bias (with mitigation), Marginal Excess Tax Burden, real-terms rebasing, WELLBY / QALY / VPF wellbeing valuation, sensitivity, switching values, EANC for unequal-life options, validation gate, and a one-line headline verdict (socially worthwhile vs financially self-sustaining). Backed by the greenbook R package (HM Treasury Green Book primitives) when available, with graceful fallback. Supports HMT Green Book, EU Better Regulation, World Bank, ADB, and Victorian HVHR. Reads a longlist markdown file directly via --from.