Results for “pre-pr”

Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery including SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom parameters, use rdkit directly.

Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery: SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom parameters, use rdkit directly.

Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery: SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom parameters, use rdkit directly.

Personal working rules, decision frameworks, and preferences for ejarbe. Invoke with /rules to surface these during any session. AUTO-TRIGGER when working with MCP servers, MCP transport, SSE, streamable HTTP, server migration, .well-known metadata, or MCP server discovery/registration.

Runs a structured 6-phase multi-agent board meeting protocol for strategic decisions, with isolated C-suite contributions, critic analysis, synthesis, founder review, and decision extraction.

Pressure-test any business idea with a five-angle adversarial panel (Critic, Champion, Analyst, Investigator, Customer) that returns a single GO/RESHAPE/KILL verdict with the cheapest test to de-risk it.

Detects rootkit presence on compromised systems by identifying hidden processes, hooked system calls, modified kernel structures, hidden files, and covert network connections using memory forensics, cross-view detection, and integrity checking techniques.

Builds an investor, product, or sales pitch deck as a PPTX file from a written brief, extracting fundamentals, flagging gaps as TODOs, drafting slides with speaker notes, and rendering with python-pptx.

Checks how well a Linear cycle is prepared. Reports per-person load in working days against available days, tickets with no estimate, tickets nobody is assigned to, oversized tickets that need splitting, work that did not finish last cycle, on-call rotation cost, and how groomed the backlog behind the cycle is. Invoke when the user says "cyclotic", "cyclotic prep", "cyclotic prep next", "cyclotic review", "cyclotic init", "cyclotic configure", "cyclotic for" a person's name, "cyclotic show cards", "cyclotic list tickets", "cyclotic explain" a person's name, or adds "-v" or "verbose" to any of those. Also invoke when the user asks whether a cycle or sprint is ready, who is over or under capacity, what carried over from last cycle, which tickets still need estimates, how the backlog looks going into planning, what is in the cycle and at what sizes, or how one person's load adds up. Read-only against Linear.

Guides agents through the full lifecycle of NeMo-RL experiments: understanding recipes, launching reproducible runs, analyzing results, and preserving human oversight with git and TSV logs.

Audits hidden assumptions in decisions or beliefs by classifying them into fact, convention, belief, or interest-driven, ranking by fragility and impact, then rebuilding conclusions from verified premises. Supports English and Chinese.

Create a structured customer interview script with JTBD probing questions, warm-up, core exploration, and wrap-up sections. Follows The Mom Test principles — no leading questions, no pitching, focus on past behavior. Use when preparing for user interviews, creating interview guides, or planning discovery research.

Translate a vague request or GitHub issue into a concrete, testable spec using five structured elements (problem, scope, acceptance criteria, edge cases, success criterion) before writing any code. Prevents scope creep, PR churn, and mid-implementation pivots.

Clarifies ambiguous or conflicting requests by researching first, then asking only judgment calls. Use when prompts say "grill me", ask hard questions, request relentless interrogation, pressure-test assumptions, clarify scope/requirements, define success criteria, or request system-design/optimization decisions.

Triage issues through a state machine driven by triage roles. Use when user wants to create an issue, triage issues, review incoming bugs or feature requests, prepare issues for an AFK agent, or manage issue workflow.

Builds a Power × Interest stakeholder map and generates a communication plan per quadrant. Use when managing a complex launch, aligning cross-functional teams, or preparing stakeholder engagement strategy. Triggers on: stakeholder management, stakeholder map, stakeholder alignment, communication plan, power interest grid, cross-functional alignment, executive alignment, managing up.

Migrates legacy AEM (6.x, AMS, on-prem) to AEM as a Cloud Service using BPA CSV or CAM/MCP target discovery, with one-pattern-per-session workflow for scheduler, replication, event listener, HTL lint, dialog, and custom widget migration.

Battle-tested PyTorch training recipes for all domains — LLMs, vision, diffusion, medical imaging, protein/drug discovery, spatial omics, genomics. Covers training loops, optimizer selection (AdamW, Muon), LR scheduling, mixed precision, debugging, and systematic experimentation. Use when training or fine-tuning neural networks, debugging loss spikes or OOM, choosing architectures, or optimizing GPU throughput.

Orchestrator for the pre-decision business-idea lifecycle — generate ideas, model them, evaluate them, validate them with customers, and only then hand off to product-soul / brainstorming. Routes through `idea-generation`, `business-modeling`, `idea-evaluation`, and `customer-discovery`. Load when the user asks to explore business ideas, find a startup idea, evaluate a venture, validate an idea, says "what business should I start", "should I build this", "is this a good business", "I have a startup idea", "evaluate this venture", "model this business", "validate this idea", "Mom Test this", "Lean Canvas this", "Business Model Canvas", "Value Proposition Canvas", "go/no-go on this idea". Pre-decision suite — once one idea is committed, hands off to `product-soul`. Does NOT design features (use `brainstorming`) or audit built products (use `reality-check`).

Autonomous biomedical AI agent framework for executing complex research tasks across genomics, drug discovery, molecular biology, and clinical analysis. Use this skill when conducting multi-step biomedical research including CRISPR screening design, single-cell RNA-seq analysis, ADMET prediction, GWAS interpretation, rare disease diagnosis, or lab protocol optimization. Leverages LLM reasoning with code execution and integrated biomedical databases.

Autonomous biomedical AI agent framework for executing complex research tasks across genomics, drug discovery, molecular biology, and clinical analysis. Use this skill when conducting multi-step biomedical research including CRISPR screening design, single-cell RNA-seq analysis, ADMET prediction, GWAS interpretation, rare disease diagnosis, or lab protocol optimization. Leverages LLM reasoning with code execution and integrated biomedical databases.

Opens plans and HTML artifacts in a local browser canvas where the human annotates elements, chats, and approves or requests changes without leaving the page. Use when presenting a plan for review, or when feedback like "move this, change that" is easier pointed at than typed.

Autonomous biomedical AI agent framework for executing complex research tasks across genomics, drug discovery, molecular biology, and clinical analysis. Use this skill when conducting multi-step biomedical research including CRISPR screening design, single-cell RNA-seq analysis, ADMET prediction, GWAS interpretation, rare disease diagnosis, or lab protocol optimization. Leverages LLM reasoning with code execution and integrated biomedical databases.

Access and analyze drug information from the DrugBank database — drug properties, interactions, targets, pathways, chemical structures, and pharmacology data. Use when working with pharmaceutical data, drug discovery research, drug-drug interaction analysis, target identification, chemical similarity searches, ADMET predictions, or any task needing detailed drug and drug-target records from DrugBank. Part of the AlterLab Academic Skills suite.

Upwork freelance coach and orchestrator for niche discovery, positioning, and specialist routing. Use when the user asks to talk to the Upwork coach, wants to find their freelance niche, build their Upwork presence, figure out positioning, or decide which Upwork specialist to run next. Triggers: 'help me with Upwork', 'find my niche', 'what should my Upwork profile say', 'Upwork coach', 'position myself on Upwork', 'I keep losing jobs on Upwork'.

Wraps RDKit in a high-level, pandas-friendly datamol interface with sensible defaults for everyday drug discovery — SMILES/SDF loading into DataFrames, molecule standardization, descriptors, fingerprints, Butina clustering, 3D conformer generation, scaffold analysis, and parallel batch processing, returning native rdkit.Chem.Mol objects. Use when running standard cheminformatics pipelines on molecule tables with minimal boilerplate; for low-level control, custom sanitization, or specialized algorithms prefer alterlab-rdkit. Part of the AlterLab Academic Skills suite.

Loads Therapeutics Data Commons (TDC, PyTDC) AI-ready drug-discovery datasets and benchmarks — ADME, toxicity, drug-target interaction (DTI), scaffold splits, and molecular oracles for therapeutic ML and pharmacological prediction. Use when fetching a standardized benchmark dataset, applying scaffold or cold-split evaluation, or sourcing labeled molecules for ADMET, toxicity, or DTI modeling. Sources data, splits, and oracles only — defer molecular featurization (ECFP/fingerprints), model training, and transformers to a molecular-ML skill (e.g. deepchem). Part of the AlterLab Academic Skills suite.

Talk to customers without leading them using Mom Test rules: discuss their life not your idea, ask about specifics in the past, and talk less. Use when the user mentions "customer interviews", "validate my idea", "users say they want it but dont buy", "leading questions", "The Mom Test", "customer feedback bias", or "interview script". Also trigger when preparing user research questions, interpreting ambiguous customer feedback, or designing customer discovery processes that avoid false positives. Covers commitment and advancement, avoiding compliments, and extracting signal from noise. For product-market fit, see jobs-to-be-done. For rapid prototype testing, see design-sprint.

Orchestrator + builder for distinctive, production-grade frontends that don't look AI-generated. Derives stack and design context from product-soul/PRD/specs, then runs the anti-slop chain — explore distinct directions, lock a DESIGN.md system, build from golden examples with mandatory polish + every interactive/empty/loading/error state, then review. Load when the user asks to build a UI, design a frontend, build a landing page or dashboard or web app, beautify or redesign a page, make a UI look premium/playful/editorial, says "build me a frontend", "make this not look AI-generated", "design this interface", "give this real polish", or "frontend design". Routes to design-direction, design-system, design-review.

Creates decision-focused PRDs and product specs — the kind that make explicit decisions, not document hopes. Make sure to use this skill whenever someone asks to write, review, draft, or improve any product document, including PRDs, feature specs, requirements docs, or product specifications. Trigger even when the user doesn't say "PRD" explicitly — phrases like "write a spec for X", "define requirements for Y", "what should my PRD include", "help me document this feature", or "my spec feels too vague" all apply. Do not attempt to write the PRD directly without consulting this skill. Produces 5-stage PRDs with behavior contracts (15-25 labeled examples for AI features), measurable success metrics with specific thresholds, precise rollout plans with percentages and ramp gates, and antipattern detection. Works for AI features, SaaS, mobile apps, and traditional software.

Translates stakeholder feature requests into validated outcome statements before any work is committed. Use this skill — proactively and without waiting to be asked — whenever a stakeholder, exec, or customer arrives with a pre-packaged solution: "we need a dashboard", "add a Slack notification", "build an export feature", "create a report", "let's add a filter", "can we just add X". Also triggers for: "how do I push back on this request", "what outcome does this feature solve", "outcome vs output", "outcomes not features", "what are we really trying to achieve", "we're being a feature factory", "I need to reframe this as a problem", "the stakeholder is pushing a specific solution", "discovery before delivery", "assumption testing", "translate this request into an outcome", "ship outcomes not features". Runs the 'One Framework. Four Questions.' protocol (Liatti + Cagan + Torres): Behavior Change → Assumption Test → Cheapest Test → Success Metric. Produces an Outcome Brief with embedded AI prompts ready to pas

When the user wants to generate, iterate, or scale ad creative — headlines, descriptions, primary text, or full ad variations — for any paid advertising platform. Also use when the user mentions 'ad copy variations,' 'ad creative,' 'generate headlines,' 'RSA headlines,' 'bulk ad copy,' 'ad iterations,' 'creative testing,' 'ad performance optimization,' 'write me some ads,' 'Facebook ad copy,' 'Google ad headlines,' 'LinkedIn ad text,' 'static ads,' 'static ad concepts,' 'ad templates,' 'iMessage ad,' 'chat reveal ad,' 'fake DM ad,' 'ChatGPT ad,' 'Apple Notes ad,' 'AirDrop ad,' 'creative strategy,' 'creative roadmap,' 'creative retro,' 'hook writing,' 'creative review page,' 'present ad creative for approval,' 'motion video ad,' 'faceless video ad,' 'animated explainer ad,' 'motion collage ad,' or 'I need more ad variations.' Use this whenever someone needs to produce ad copy at scale or iterate on existing ads. For campaign strategy and targeting, see ads. For landing page copy, see copywriting.

Drafts and revises academic papers through a 12-agent pipeline with hardened LaTeX output (apa7 document class, justified text, table column-width formula, centered bilingual abstracts, standardized font stack, PDF compiled from LaTeX), supporting IMRaD, literature review, theoretical, case study, policy brief, and conference paper structures, APA 7.0 (default), Chicago, MLA, IEEE, and Vancouver citation formats, bilingual zh-TW plus EN abstracts, and multi-format output (LaTeX, DOCX, PDF, Markdown). Use when the request mentions write paper, academic paper, paper outline, write abstract, revise paper, check citations, convert to LaTeX, guide my paper, parse reviews, revision roadmap, or 寫論文, 學術論文, 論文大綱, 寫摘要, 修改論文, 檢查引用, 引導我寫論文, 帶我規劃論文, 逐章規劃, 論文架構, 審查意見, 修訂路線圖. Its citation-check mode formats and inserts citations while drafting; for a standalone anti-hallucination check that cited references actually exist prefer alterlab-citation-verifier instead. Part of the AlterLab Academic Skills suite.