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Agent Media OS — resolve any media need (BGM, SFX, image, icon) into a frozen local file + ledger record. One verb (`resolve`) handles the full cascade — project cache, global cache, HeyGen catalog search, freeze, register. Keeps search noise on disk, hands the agent a path. Use when a composition needs background music, sound effects, images, or icons.

Guides ISO 27701 Privacy Information Management System implementation extending ISO 27001/27002. Covers Clause 5 PIMS-specific requirements, Clause 6 PIMS guidance for ISO 27002, Clause 7 PII controller guidance (Annex A), Clause 8 PII processor guidance (Annex B), gap assessment, and certification path. Keywords: ISO 27701, PIMS, privacy management system, ISO 27001 extension, certification, Annex A, Annex B.

Enriches vague, low-detail prompts into structured, agent-optimized XML before execution. INVOKE IMMEDIATELY — before any tool use or file reads — when you detect any of these signals: prompt under 10 words with no file path or error message; vague action verbs with no object ("fix the bug", "make it better", "clean this up", "refactor this", "optimize performance", "improve the UI", "add authentication", "add payments", "add notifications", "build the feature"); CLARIFIER_ADVISORY in your context window; user says "clarify", "help me describe this", "enrich this prompt", "structure my request". Also triggers on: "make this work", "it's broken", "it looks bad", "add X" with no further detail, "implement Y" with no constraints. Do NOT trigger on: prompts ending with ?, prompts containing error messages or stack traces, prompts with specific file paths, prompts already containing acceptance criteria or success metrics.

Build Motion (Framer Motion) React animations — declarative motion components, variants, AnimatePresence, layout transitions, scroll effects, and inline SVG pathLength. Load when the user asks to animate with Motion, Framer Motion, motion.div, AnimatePresence, layout animation, whileInView, or React enter/exit transitions. Also triggers on "framer-motion", "motion/react", "useReducedMotion", or "React animation library". React/Next only — not README embeds or non-React.

Create and manage Claude Code skills following Anthropic best practices. Use when creating new skills, modifying skill-rules.json, understanding trigger patterns, working with hooks, debugging skill activation, or implementing progressive disclosure. Covers skill structure, YAML frontmatter, trigger types (keywords, intent patterns, file paths, content patterns), enforcement levels (block, suggest, warn), hook mechanisms (UserPromptSubmit, PreToolUse), session tracking, and the 500-line rule.

Create and manage Claude Code skills following Anthropic best practices. Use when creating new skills, modifying skill-rules.json, understanding trigger patterns, working with hooks, debugging skill activation, or implementing progressive disclosure. Covers skill structure, YAML frontmatter, trigger types (keywords, intent patterns, file paths, content patterns), enforcement levels (block, suggest, warn), hook mechanisms (UserPromptSubmit, PreToolUse), session tracking, and the 500-line rule.

Create and manage Claude Code skills following Anthropic best practices. Use when creating new skills, modifying skill-rules.json, understanding trigger patterns, working with hooks, debugging skill activation, or implementing progressive disclosure. Covers skill structure, YAML frontmatter, trigger types (keywords, intent patterns, file paths, content patterns), enforcement levels (block, suggest, warn), hook mechanisms (UserPromptSubmit, PreToolUse), session tracking, and the 500-line rule.

Audit and attack session cookies via missing Secure/HttpOnly/SameSite attributes, overly broad Domain/Path scope, non-expiring persistent cookies, absent __Host- and __Secure- prefixes, browser cache leakage (Cache-Control: no-store missing), session token predictability via Burp Sequencer analysis, server-side session not invalidated on logout, and SSO single-logout bypass. Tools: Burp Suite Repeater/Sequencer, OWASP ZAP, EditThisCookie, Tamper Data, Cookiebro.

Use to analyse touch time vs elapsed time across the resolution path — queue wait, customer wait, back-office wait, and where elapsed time hides real delay. Trigger for "flow efficiency", "touch time vs elapsed time", "where is the time going", "customers waiting on us", back-office bottlenecks, idle time in cases, or end-to-end time much longer than handle time.

Use to design or audit the executive escalation path for a major account — intake, ownership, communication cadence and follow-through — so escalations are resolved rather than merely attended. Trigger for "design our escalation process for key accounts", "an executive escalation went badly", "customer went to our CEO", red account war rooms, or escalations that get attention and then quietly stall.

Run a standard Claude Code review of local git changes in this repository. Args: --wait, --background, --base <ref>, --scope <auto|working-tree|branch>, --model <model>, --effort <low|medium|high|xhigh|max>. Defaults to opus + xhigh effort. Use as the default path for ordinary code-review requests when the user did not explicitly ask for stronger adversarial scrutiny or for Claude to own the implementation work.

Deep Confidence Harness — a thinking, planning, and execution framework that forces structured reasoning before acting. Combines Monte Carlo scenario analysis, calibrated confidence, multi-perspective debate, and optimal path planning. Use before any complex decision, build, or task. Activates on: 'deep confidence', 'think before you act', 'plan first', 'Atlas mode', 'reason through this', 'what should I do', 'think this through', 'best approach', 'reason carefully', 'plan and execute'.

Calculate the Maryland Aggregate Pathology Index (MAPI) on a deceased donor procurement kidney biopsy to predict graft survival and decide single vs dual vs discard allocation. Trigger when a clinician asks "what's the MAPI score", "interpret donor kidney biopsy", "should I use this marginal kidney", "MAPI cutoff for transplant", "procurement biopsy scoring", or has histology results from a deceased donor kidney and needs an objective grading.

Run the quarter-boundary ritual — roll the quarter-scoped project folders, archive finished projects, grade the closing quarter's GOALS/OKRs, and draft the new quarter's goals behind an approval gate. Trigger on /quarter-rollover, "quarter rollover", "roll the quarter", "close out Q2", "new quarter setup", or when tools/quarter_path.py --check reports drift. Distinct from /triage-tasks (daily gate) and /audit (repo health check).

Close out a work session safely. Verifies every change is committed, pushed, and green, confirms the work is live and verified, updates the notes for next time, and hands back a summary with links and a rollback path. Trigger on "close out the session", "wrap up", "lock it up", "are we good to close", "session QA", "end of session", or any moment before you stop or hand off.

Find and query PI assets using MATLAB's Industrial Communication Toolbox. Two paths: (1) direct PI tag lookup via piclient + tags when user provides a tag name or description (R2022a+), (2) Asset Framework navigation via afclient when user needs element/attribute hierarchy (R2026a+). Use when working with PI AF servers, PI Data Archive tags, asset hierarchies, element templates, attribute lookup, or historical data from OSIsoft PI systems.

Use before any complex or ambiguous task where the path forward is unclear. For breaking down multi-step problems, choosing between approaches, clarifying vague requirements, identifying hidden assumptions, planning before building, and preventing costly mistakes from starting in the wrong direction. Activate when user says "how should I approach this", "what's the best way to", "I'm not sure how to", or presents a problem without a clear solution.

Product strategy, market validation, commercial filtering, and MVP definition for Nick's workflow. Use when turning vague ideas into product plans, evaluating startup opportunities, identifying real market gaps, deciding if an idea should be killed before build, prioritizing features, shaping positioning, defining monetization, or judging whether a concept is strong enough to deserve design and engineering effort. Focus on painful problems, clear buyers, credible wedges, practical validation, and realistic paths to revenue.

Layer alternative channels / scrapers / data sources with explicit fall-through, where each rung covers a different failure mode. Use when interacting with the world (sending a notification, fetching from a third party, detecting a state change, authenticating) and the single canonical path could fail in known ways. Distinct from retrying — retries handle transient failures; fallback chains handle modal ones (channel down, API gone, cookie expired). Three layers tops; the terminal rung is loud.

Federal Other Transaction (OT) prototype bid strategist for 10 USC 4021 research and 10 USC 4022 prototype/4022(f) production-follow-on agreements. USE WHEN the user asks to "build an OT bid", "respond to this OT solicitation", "estimate should-cost for an OT prototype", "is this milestone price reasonable", "compare 4022(d) cost-share paths", "team with an NDC to avoid 1/3 cost share", "OT price-to-win", or "TRL milestone phasing" — any milestone-based prototype scoping, OT cost stack, or 4022(d) cost-share strategy question. Reconstructs the AO's TRL phasing from the active workspace KG, picks the 4022(d) path that minimizes our exposure, builds a per-milestone cost stack from BLS OEWS + GSA CALC+ + GSA Per Diem, and emits a JSON envelope handed to `proposal-generator`. DO NOT USE FOR FAR-based contracts (`price-to-win`/`proposal-generator`), incumbent research (`competitive-intel`), FAR clause audit (`compliance-auditor`), or prime-to-sub SOW drafting (`subcontractor-sow-builder`).

Kit de ferramentas de patologia computacional para análise de imagens de lâminas inteiras (WSI) e dados de imagem multiparamétrica. Use esta habilidade ao trabalhar com lâminas de histopatologia, imagens coradas com H&E, imunofluorescência multiplex (CODEX, Vectra), proteômica espacial, detecção/segmentação de núcleos, construção de gráficos de tecido ou treinamento de modelos ML em dados de patologia. Suporta 160+ formatos de lâmina incluindo Aperio SVS, NDPI, DICOM, OME-TIFF para fluxos de trabalho de patologia digital.

Access the COSMIC catalogue of somatic mutations in cancer to query somatic mutations, the Cancer Gene Census, mutational signatures, and gene fusions (authentication required). Use when curating known cancer driver genes, looking up recurrent somatic mutations in a gene, or interpreting mutational signatures for cancer research and precision oncology. Not for germline pathogenicity calls (use alterlab-clinvar) or interactive cohort visualization like OncoPrints and survival from study data (use alterlab-cbioportal). Part of the AlterLab Academic Skills suite.

Query BindingDB for measured protein-ligand binding affinities (Ki, Kd, IC50, EC50) via its keyless REST API or the full TSV download, searching by target (UniProt ID), compound (SMILES), or pathogen. Use when looking up experimental binding constants, profiling inhibitors of a protein target, doing lead optimization, polypharmacology analysis, or structure-activity relationship (SAR) studies; for curated bioactivity mining or drug-like compound library screening at scale prefer alterlab-chembl instead. Part of the AlterLab Academic Skills suite.

Orchestrator for the learn-from suite - auto-detects source type (academic paper, GitHub repo, blog/web article, or in-conversation learnings) and routes to the correct sub-skill for credibility check, security scan, insight extraction, and application. Load when the user says "learn from", "learn from this", "extract insights from", "apply learnings from", "what can we learn from", or provides a URL, file path, or pasted content that should be ingested as knowledge. Single entry point for all learning workflows.

Access ClinPGx pharmacogenomics data (the successor to PharmGKB) to query gene-drug interactions, CPIC/DPWG dosing guidelines, drug labels, and pharmacogene records. Use when interpreting pharmacogenes (CYP2D6, CYP2C19, TPMT, DPYD, SLCO1B1), looking up genotype-guided drug dosing, checking PGx drug-safety associations (e.g. HLA-B*57:01 and abacavir), or supporting precision medicine and clinical pharmacogenomics decisions. For star-allele definitions/frequencies see PharmVar; for germline/somatic variant pathogenicity see alterlab-clinvar. Part of the AlterLab Academic Skills suite.

Triage a raw, vague issue or bug report into a structured document that names what is known, what is missing, and what to do next. Use when an incoming issue, bug report, or problem description is too vague or incomplete for investigation or planning, and recommend the right next han skill. Does not investigate root causes or trace code paths — use investigate for debugging, diagnosis, and root cause analysis. Does not plan features or build solutions — use plan-a-feature or plan-implementation for that.

Query the STRING API for protein-protein interactions (59M proteins, 20B interactions across 5000+ species), building interaction networks, discovering functional partners, and running GO/KEGG/Pfam enrichment on protein lists. Use when constructing a protein-protein interaction network, expanding from seed proteins to functional partners, or running PPI-based enrichment for systems biology; for curated metabolic pathway maps and reactions prefer alterlab-kegg, and for protein sequences, annotations, or accession ID mapping prefer alterlab-uniprot instead. Part of the AlterLab Academic Skills suite.

Creates, analyzes, and visualizes complex networks and graphs in Python with NetworkX. Use when working with network/graph data structures, analyzing relationships between entities, computing graph algorithms (shortest paths, centrality, clustering), detecting communities, generating synthetic networks, or visualizing topologies — applicable to social, biological, transportation, citation, and any pairwise-relationship networks. This is classical graph analytics, not deep learning — for training graph neural networks (GCN/message passing, node/edge/graph classification on Cora-style data) use alterlab-torch-geometric instead. Part of the AlterLab Academic Skills suite.

Generates setup table and page objects for Business Central following singleton pattern. Creates setup tables with single-record pattern, primary key field, setup page with auto-initialization on OnOpenPage, GetRecordOnce codeunit helper for performance, and common setup field patterns (Enable/Disable toggles, Default values, Number Series references, Path fields, User IDs). Handles DrillDownPageID and LookupPageID for seamless navigation. Supports multi-tenant and cloud-ready patterns. Use when creating setup tables, implementing module configuration, adding settings tables, creating admin configuration pages, building extension setup, or implementing singleton setup patterns for Business Central.

Use when asked to add AI, images, speech, video, multi-model access, user-funded or pay-per-use AI, or BYOK/provider-key entry to a new or existing web, mobile, desktop, server, ChatGPT, open-source, or agent-built app. Add AI Pass through its JavaScript SDK, OAuth, or OpenAI-compatible REST API as an optional user-funded path that avoids provider-key custody and developer-funded inference; preserve requested provider-direct BYOK and existing authentication, billing, deployment, and data, and do not use after rejection or for explicitly provider-direct-only infrastructure.

Break a stuck or complex problem into the smallest sub-question that, if answered, unlocks the next step — then answer it and repeat until the path forward is clear. Load when a problem feels genuinely stuck, when reasoning keeps circling, or when deep-thinking diagnoses a Socratic frame. Also triggers on "I keep going in circles", "what is the real question here", "help me reason through this step by step", "unstick my thinking", "recursive questioning", "what is the root question". Based on the recursive Socratic questioning method (EMNLP 2023) which outperforms CoT and Tree-of-Thought on complex reasoning tasks.

Turn "let's stay in touch" into a dated plan to signature that you and the champion own together. Lays out every milestone from today to signed, with an owner and a date on each, plus the exit criteria that say the deal is real. Written to send, so the buyer can react to something concrete. Built for B2B sales teams, customizable to your process and your CRM. Trigger on "build a mutual action plan", "close plan", "MAP for this deal", "path to signature", "what are the next steps", or any late-stage deal you need to drive.

Assess the test suite of a codebase — where tests are missing, where they exist but are weak, and which gaps actually matter. Use this skill whenever the user asks about test coverage, test quality, "are there enough tests", "where should we add tests", testing gaps, test debt, untested code paths, flaky tests, or generally wants to know whether a codebase is well-tested. Trigger even on casual phrasings ("is this tested?", "what's the test situation?", "audit our tests"). This skill does NOT write tests — it only assesses what exists and identifies what's missing. For test generation, this is the wrong skill.

Scrapes pump.fun/board using Chrome browser automation to extract the top 100 trending Solana tokens and writes structured markdown for a trading agent to consume. Use this skill any time you need to: scan pump.fun for new tokens, refresh the pump.md token list, run the scheduled board scrape, collect Solana meme token data, or build/update a trading watchlist from pump.fun. Even if the user says something casual like "check pump" or "update the token list" or "what's trending on pump", use this skill. The output file path and format are configurable but default to /Users/8bit/solanaos/pump.md.

Capture exact React element context from a live browser UI and hand it to an AI coding agent as component name, source file path, line number, and HTML. Use when the user wants `react-grab`, element-context copy, component-source lookup from the browser, clipboard-to-agent React debugging, or MCP-backed element selection for React apps. Not for generic browser automation or login/session reuse (`browser-harness`, `playwriter`), broad UI annotation/review (`agentation`), React performance audits (`react-best-practices`), or general design-system work (`design-system`). Triggers on: react-grab, grab element context, copy component to AI, browser component picker, React component inspector, clipboard component source, get element context from browser, grab UI element.

Set up worker environment and per-worker state for parallel pools. Use when code needs paths, environment variables, database connections, loaded libraries, or expensive objects available on workers before parfor/parfeval runs. Teaches parallel.pool.Constant, parfevalOnAll, and parpool name-value pairs. Also use when refactoring existing code that uses spmd for side-effect setup (an anti-pattern). Triggers: worker setup, pool constant, per-worker state, non-serializable, loadlibrary on workers, database connection parfor, addpath workers, spmd before parfor, worker environment, reduce parfor overhead, parfor setup, resource creation in parallel loop, cannot serialize error, undefined function or variable on workers error, load data per worker, reduce data transfer, parallelize setup, improve parallel code.