Results for “cell-signaling”

Explains cellular structures, membrane transport, energetics, signaling, and division, connecting molecular events to organismal function.

Use when studying cell biology.

Notebook Cell References

Use this skill when conditioning, loading, preparing, or labeling signal data for analysis or ML training. Covers: cleaning a single signal (fill gaps, remove drift, deoutlier, denoise, resample/align a time base) BEFORE analysis; building a `signalDatastore` pipeline; creating a `labeledSignalSet` for Signal Labeler; deriving labels (filename, folder, in-file, ROI, time-frequency ROI); stratified train/val/test splits; framing long signals; parallel processing; and shaping datastore output for `trainnet`. Triggers include "clean up this signal", "remove drift / detrend", "fill gaps", "remove spikes / outliers", "denoise", "resample to a uniform rate", "align channels", "labels from filenames", "stratified split", "prepare for Signal Labeler", and function names like `fillgaps`, `fillmissing`, `detrend`, `filloutliers`, `smoothdata`, `resample`, `synchronize`, `signalDatastore`, `labeledSignalSet`, `filenames2labels`, `folders2labels`, `splitlabels`, `framesig`, `framelbl`, `createDatastores`.

Annotates single-cell RNA-seq data by scoring marker genes, transferring labels with CellTypist, or reasoning over cluster markers with an LLM.

Use when triaging a study before any writing — stress-tests whether it clears Cell's bar (a complete, mechanistic, hypothesis-driven story with multiple converging lines of evidence) or belongs at a sibling. Use this first to decide Cell vs Molecular Cell vs Cell Reports vs Cell Reports Medicine before investing in framing or figures.

Annotates single-cell RNA-seq data by scoring marker genes, transferring labels with CellTypist, or reasoning over marker lists with an LLM.

Query the CZ CELLxGENE Census programmatically for versioned public single-cell and spatial transcriptomics data, enabling efficient access to cell metadata, gene expression slices, summary counts, and embeddings without downloading whole datasets.

Predicts tissue or cell-type gene expression (log TPM and TPM) from a TSS-centered DNA sequence using the hosted Genomic Intelligence G0 Expression model, conditioned on a free-text cell-type description.

Spatial region-aware cell matching for CODEX/scRNAseq integration

Batch Signal Isolation with Recipe-Driven Processing

Processes and analyzes multiple physiological signals (ECG, respiration, EDA, EMG, PPG, EOG) together using NeuroKit2, including cross-signal features like RSA and event-related analysis.

Use when deciding which cell-* sub-skill to invoke next, or when sequencing a manuscript from significance test through reviewer rebuttal for Cell (Cell Press). Routes — it does not replace — the specialized skills.

Use to finalize Cell Press display items — column-width sizing, minimum fonts, RGB, show-the-data with defined error bars/n/replicate type, scale bars, colorblind-safe palettes, multi-panel discipline, stand-alone legends, and image integrity.

Score a clinical ASR manifest against a chosen NIM, produce a five-section KER leaderboard, and route the user via a post-eval decision tree.

Use to find upgrade, seat-growth and new-use-case signals that customers give support and nobody routes anywhere. Trigger for "find upsell opportunities in support", "customers hitting plan limits", "which accounts are asking about enterprise features", expansion signals from tickets, or support-sourced pipeline.

Publish and consume blockchain-verified trading signals on Base. Register as a signal provider, publish trades with transaction hash proof, and subscribe to top performers via REST API.

Full pipeline from signal detection to scored lead in CRM. Chains signal-scanner, lead-scorer, and crm-writer into one flow.

Use after Cell reviews arrive to triage the decision, prioritize the (often substantial) new experiments by impact × feasibility, and draft a point-by-point response that is respectful, evidence-led, and closes the "completeness" gaps reviewers demand. Do not run before the experiments and revision are actually done.

`task-agent`/`review-agent`: use when CPU, memory, I/O, database, network, rendering, or cost needs measured bottleneck evidence; skip without a profiling need.

Transaction-verified trading signals on Base. Register agent as signal provider, publish trades with TX hash proof, consume signals from top performers via REST API. All track records verified against blockchain data. No fake performance claims. Triggers on: "publish signal", "post trade signal", "register provider", "subscribe to signals", "copy trade", "bankr signals", "signal feed", "trading leaderboard", "read signals", "get top traders".

Via modeling: pads, antipads, ground return vias, GRV placement, and signal integrity for high-speed layer transitions. TRIGGER: user asks to model a via, design a via transition, place ground return vias, analyze via performance, or check signal integrity through layer transitions. Invoke BEFORE writing code — only viaSingleEnded exists (no viaDifferential), and the location format is non-obvious. SKIP: general signal integrity without vias (use matlab-analyze-em), transmission line design (use matlab-design-pcb-transmission-line), PDN analysis (use matlab-analyze-pcb-pdn), material/stackup setup only (use matlab-manage-pcb-material).

Use to surface fraud, scam and financial-crime signals that customers describe to support before detection systems see them, and to check whether agents recognised and routed them. Trigger for "are customers reporting scams", "new scam pattern targeting our customers", "did we spot the fraud signals", authorised push payment scams, "customer was coached by someone on the phone", or fraud reports arriving through support.

Applies physical principles to model biological systems, including protein folding, membrane transport, molecular forces, and neural signaling.

Angular forms: Signal Forms (experimental) and Reactive Forms. Trigger: When working with forms, validation, or form state in Angular.

Detect poisoned training data and backdoored models across the ML pipeline using statistical analysis, activation clustering, and spectral signatures.

Build lean, opinionated products using the 37signals philosophy from Getting Real, Rework, and Shape Up. Use when the user mentions "Getting Real", "Rework", "Shape Up", "37signals", "Basecamp method", "six-week cycles", "fixed time variable scope", "appetite vs estimates", "betting table", "breadboarding", "fat marker sketch", "build less", "underdo the competition", or "opinionated software". Also trigger when cutting scope to ship faster, running small teams, avoiding long-term roadmaps, or eliminating meetings. Covers shaping, betting, building, and the art of saying no. For MVP validation, see lean-startup. For design sprints, see design-sprint.

Use to measure customer effort from behavioural signals instead of CES surveys, and to audit whether a composite effort score is honest. Trigger for "customer effort score", "behavioural CES", effort without survey, repeat contacts and channel switches, transfers and reopens, or "our CES doesn't match operational data".

Use to design or audit the support contribution to a customer health score, so the score predicts something instead of averaging weakly-related signals into a colour. Trigger for "build a customer health score", "add support signal to health scoring", "our health scores don't predict churn", red/amber/green account scoring, or a health score nobody trusts.

当在个人发展的某个领域（心智、身体、精神、职业）达到“失调阶段”（即对现状感到厌倦、停滞或不满，但尚未麻木）时，用于主动进入一个能加速学习和成长的“心流”或“痴迷”状态（即“渠道”）

Turn a pile of accounts into a stack-ranked priority list with a reason on every row. A layered score (gates first, then an evidence-weighted base rank over the signals you actually have, then bounded boosts for product usage and buyer intent) that stays fair across channels and never scores a blank field as a zero. Built for B2B GTM teams, customizable to your signals and your ICP. Trigger on "score these accounts", "rank by fit", "composite ICP score", "stack-rank my list", "who should I work first", "prioritize these leads", or any multi-signal account qualification.

Outreach triggered by hiring signals that indicate need for agency services

AI 原生的潜在客户情报和外联流水线。用 agent 驱动的信号评分、共同关系人排名、暖场路径发现、来源语音建模和多渠道外联（邮件、LinkedIn、X），替代 Apollo、Clay 和 ZoomInfo。在用户想找到、评估并联系高价值联系人时使用。

Multi-project signal isolation with cascading recipe resolution

当意识到自己处于长期迷茫、缺乏动力阶段，需要系统性方法走出困境时