Results for “chainalysis”

Process and analyze high-throughput sequencing data with deepTools for quality control, normalization, comparison, and publication-quality visualizations of ChIP-seq, RNA-seq, and ATAC-seq experiments.

Design, tune, and evaluate production RAG pipelines with deterministic tools for chunking, pipeline design, and retrieval evaluation.

Stream-JSON chaining for multi-agent pipelines, data transformation, and sequential workflows

Cross-platform Python library for quantum computing, quantum machine learning, and quantum chemistry. Enables building and training quantum circuits with automatic differentiation, seamless integration with PyTorch/JAX/TensorFlow, and device-independent execution across simulators and quantum hardware (IBM, Amazon Braket, Google, Rigetti, IonQ, etc.). Use when working with quantum circuits, variational quantum algorithms (VQE, QAOA), quantum neural networks, hybrid quantum-classical models, molecular simulations, quantum chemistry calculations, or any quantum computing tasks requiring gradient-based optimization, hardware-agnostic programming, or quantum machine learning workflows.

Cleans credit risk data and screens variables for pre-loan modeling through an 11-step pipeline covering missing rate calculation, IV/PSI filtering, null importance denoising, and correlation removal.

Detects DNS tunneling by computing Shannon entropy of DNS query names, analyzing query length distributions, inspecting TXT record payloads, and identifying high subdomain cardinality using scapy for packet capture analysis.

Simplify molecular cheminformatics with a Pythonic wrapper around RDKit for SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, and parallel processing.

Model, simulate, and optimize Serializer/Deserializer (SerDes) systems — serial and parallel links — using MATLAB SerDes Toolbox. Design NRZ and PAM-N links (PAM3 through PAM16) — explore equalization architectures (FFE, CTLE, DFE), sweep or optimize parameters with genetic algorithms, and characterize channels from loss models, S-parameter files, or crosstalk scenarios. Process captured waveforms through equalization chains, build eye diagrams, and decompose jitter. Deliver IBIS-AMI models for Tx, Rx, Redriver, or Retimer by exporting to Simulink and compiling .ami/.ibs/.dll/.so files. Covers the full arc from initial design exploration and parameter optimization to compliance testing and compiled model validation, including custom datapath blocks for nonstandard equalization.

Cleans datasets, detects anomalies, generates reports, and creates visualizations using pandas, scikit-learn, and plotting libraries to turn raw data into client-ready deliverables.

Three-phase vulnerability chain analysis — parallel agents find individual weaknesses, then a synthesis step identifies which combinations escalate to critical impact. Inspired by Strix (usestrix/strix) "Graph of Agents" pentesting model.

Reads and preprocesses 5-minute stock candlestick CSV data, then clusters the time series using tslearn's TimeSeriesKMeans, including data cleaning, percentage change calculation, model training, saving, and representative sample extraction.

Analyzes malware-generated network traffic from PCAP files to identify C2 protocols, data exfiltration, DNS tunneling, and beaconing patterns using Wireshark, Zeek, Suricata, and Python.

Evaluates account-level drawdown and losing-streak rules from local thesis files to decide whether new trade risk is allowed, without external APIs.

Analyze proteomics and metabolomics mass spectrometry data with PyOpenMS: read/write MS file formats, process spectra, detect and quantify features, identify peptides and proteins, and run end-to-end LC-MS/MS pipelines using ready-to-run scripts.

Catalysis Based Testing Skill

Catalysis Design Expert Skill

Applies medicinal-chemistry filters with the medchem library — drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, and molecular complexity metrics for compound prioritization and library cleanup. Use when filtering or triaging a compound library, flagging PAINS or reactive groups, or assessing drug-likeness of candidate molecules. Part of the AlterLab Academic Skills suite.

Automates genome-wide association studies from genotype files to publication-ready results, running PLINK2 QC and REGENIE regression with Manhattan and QQ plots.

Apply medicinal chemistry filters for compound triage: drug-likeness rules (Lipinski, Veber, CNS), structural alert catalogs (PAINS, NIBR, ChEMBL), complexity metrics, and a custom query language for library filtering.

Predict molecular properties, train graph neural networks, and run drug discovery workflows using DeepChem's featurizers, models, and MoleculeNet benchmarks.

Filters and prioritizes compound libraries in drug discovery using drug-likeness rules, structural alerts, complexity metrics, and a query language.

Use this skill for on-chain data, explorers, Dune-style queries, wallets, transfers, contract events. Trigger when the task involves crypto work related to Onchain Data Analytics, production implementation, audits, debugging, strategy, or validation.

Python performance profiling with cProfile, tracemalloc, and line_profiler. Use for identifying bottlenecks and memory issues. USE WHEN: user mentions "Python profiling", "cProfile", "memory profiling", asks about "Python performance", "tracemalloc", "line_profiler", "py-spy", "Python optimization", "Python memory leak" DO NOT USE FOR: Java/Node.js profiling - use respective skills instead

Process and analyze mass spectrometry data with the Matchms Python library, including importing spectra, filtering peaks, calculating similarity scores, and building reproducible analytical workflows.

Investigate supply chain attack artifacts including trojanized software updates, compromised build pipelines, and sideloaded dependencies to identify intrusion vectors and scope of compromise.

Spectral similarity and compound identification for metabolomics. Use for comparing mass spectra, computing similarity scores (cosine, modified cosine), and identifying unknown compounds from spectral libraries. Best for metabolite identification, spectral matching, library searching. For full LC-MS/MS proteomics pipelines use pyopenms.

Convert chemical structures (SMILES or RDKit molecules) into numerical representations for machine learning using 100+ featurizers, including ECFP, MACCS, descriptors, and pretrained models like ChemBERTa.

Detect and humanize AI-generated Chinese text. 20+ rule detection categories plus statistical features (sentence-length CV, short-sentence fraction, comma density, perplexity, GLTR, DivEye) plus scene-aware LR fusion (rule × 0.2 + LR × 0.8) trained on three scenes: general / academic / longform 长文本 (≥1500 字)。Unified CLI: ./humanize {detect,rewrite,academic,style,compare}. 8 style transforms (casual/zhihu/xiaohongshu/wechat/academic/literary/weibo/novel)。 Multi-paragraph rewriting (paragraph length CV、跨段 trigram 重复) plus best-of-N humanize (默认 N=10 取最低 LR)。165 replacement patterns + CiLin 同义词词林 38873 with collision blacklist。 Academic paper AIGC reduction for CNKI/VIP/Wanfang (知网/维普/万方 AIGC 检测降重)。 Pure Python, no dependencies, offline。v5.0.0 — HC3 fused 准确率 95%、学术 hero 100→35 (-65)、 工作汇报 96→13 (-83)、长篇博客 96→41 (-55)。 Use when user says: "去AI味", "降AIGC", "人性化文本", "humanize chinese", "AI检测", "AIGC降重", "去除AI痕迹", "文本改写", "论文降重", "知网检测", "维普检测", "AI写作检测", "让文字更自然", "detect AI text", "humanize text", "reduce AIGC sc

Build multi-step AI content creation pipelines combining image, video, audio, and text using the inference.sh CLI.

丁磊（互联网创业）认知与表达框架（压缩蒸馏）：佛系老板、游戏与音乐品味人设 触发：网易、养猪梗 等。非替网易发言

袁朗（军旅剧虚构）认知与表达框架（压缩蒸馏）：老 A 冷血人设、试探与打磨、精英残酷浪漫 触发：士兵突击 等。虚构

Python interface to OpenMS for mass spectrometry data analysis. Use for LC-MS/MS proteomics and metabolomics workflows including file handling (mzML, mzXML, mzTab, FASTA, pepXML, protXML, mzIdentML), signal processing, feature detection, peptide identification, and quantitative analysis. Apply when working with mass spectrometry data, analyzing proteomics experiments, or processing metabolomics datasets.

Clusters raw detection tickets into reusable edge concepts with thesis, invalidation signals, and strategy playbooks before strategy design.

NGS analysis toolkit. BAM to bigWig conversion, QC (correlation, PCA, fingerprints), heatmaps/profiles (TSS, peaks), for ChIP-seq, RNA-seq, ATAC-seq visualization.

Query ChEMBL via the chembl_webresource_client Python client for curated bioactive molecules and drug-like compound libraries at scale — search compounds by structure or physicochemical properties, retrieve bioactivity measurements (IC50, Ki, EC50), and find inhibitors of a target. Use when screening chemical libraries, mining curated bioactivity for a protein, running SAR studies, or sourcing medicinal-chemistry data; for measured protein-ligand binding affinities (Ki/Kd/IC50) prefer alterlab-bindingdb instead. Part of the AlterLab Academic Skills suite.