Results for “clindoc”

Queries the ClinPGx REST API for pharmacogenomic gene-drug data, clinical annotations, CPIC guidelines, and FDA drug labels, generating markdown reports with CSV tables.

Query the ClinPGx API for pharmacogenomic gene-drug data, clinical annotations, CPIC guidelines, and FDA drug labels.

Loads Therapeutics Data Commons (TDC, PyTDC) AI-ready drug-discovery datasets and benchmarks — ADME, toxicity, drug-target interaction (DTI), scaffold splits, and molecular oracles for therapeutic ML and pharmacological prediction. Use when fetching a standardized benchmark dataset, applying scaffold or cold-split evaluation, or sourcing labeled molecules for ADMET, toxicity, or DTI modeling. Sources data, splits, and oracles only — defer molecular featurization (ECFP/fingerprints), model training, and transformers to a molecular-ML skill (e.g. deepchem). Part of the AlterLab Academic Skills suite.

Clawdex — dual-engine coding agent. Claude Code (reasoning + planning) + OpenAI Codex (fast execution) + Browser Use boxes (web research) + Upstash compute boxes (isolated sandboxes).

Wraps RDKit in a high-level, pandas-friendly datamol interface with sensible defaults for everyday drug discovery — SMILES/SDF loading into DataFrames, molecule standardization, descriptors, fingerprints, Butina clustering, 3D conformer generation, scaffold analysis, and parallel batch processing, returning native rdkit.Chem.Mol objects. Use when running standard cheminformatics pipelines on molecule tables with minimal boilerplate; for low-level control, custom sanitization, or specialized algorithms prefer alterlab-rdkit. Part of the AlterLab Academic Skills suite.

Simplify molecular cheminformatics with a Pythonic wrapper around RDKit for SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, and parallel processing.

Diffusion-based molecular docking. Predict protein-ligand binding poses from PDB/SMILES, confidence scores, virtual screening, for structure-based drug design. Not for affinity prediction.

Diffusion-based molecular docking. Predict protein-ligand binding poses from PDB/SMILES, confidence scores, virtual screening, for structure-based drug design. Not for affinity prediction.

Diffusion-based molecular docking. Predict protein-ligand binding poses from PDB/SMILES, confidence scores, virtual screening, for structure-based drug design. Not for affinity prediction.

Test your understanding of MkDocs, Material theme, configuration, navigation, version control, and GitHub deployment with these questions.

Therapeutics Data Commons. AI-ready drug discovery datasets (ADME, toxicity, DTI), benchmarks, scaffold splits, molecular oracles, for therapeutic ML and pharmacological prediction.

Provides a catalog of sales prompts covering pipeline management, prospecting, closing, proposals, objections, retention, and sales intelligence, with behavioral frameworks like SPIN, Challenger, and MEDDIC.

Draft an internal legal research memo for the supervising attorney with verified authority and flagged open questions.

Scaffold a new Clade skill end-to-end — interviews for use cases and trigger phrases, generates SKILL.md + prompt.md with spec-validated frontmatter (bilingual triggers, NOT-for disambiguation), wires golden-set routing tests, and runs the lint gate before committing

Therapeutics Data Commons. AI-ready drug discovery datasets (ADME, toxicity, DTI), benchmarks, scaffold splits, molecular oracles, for therapeutic ML and pharmacological prediction.

Drive Moli (`moli`), Lexmount's open-source headless browser for AI agents, built around on-demand rendering: real JavaScript, DOM, and CSS by default, with layout and pixels computed only when explicitly requested via `--layout`. Use when the user wants to fetch/extract a live JavaScript-rendered page as Markdown/HTML/JSON/semantic-tree, capture a screenshot or PDF, run a small bounded crawl, start a CDP/WebDriver automation server for Playwright/Puppeteer, replace a Chromium/ChromeDriver dependency, or diagnose readiness/network/frame issues on a rendered page. Triggers on: "moli fetch", "moli serve", "headless browser for agents", "on-demand rendering browser", "CDP server without Chrome", "structure-first web scraping", "Lexmount browser", "moli-webfetch", "moli-cdp-server".

Predict 3D binding poses of small molecule ligands to protein targets using diffusion-based molecular docking, supporting single complexes, batch processing, and virtual screening.

Generate professional clinical decision support documents for pharmaceutical and clinical research, including biomarker-stratified cohort analyses and evidence-based treatment recommendation reports with GRADE grading, statistical analysis, and publication-ready LaTeX/PDF output.

Update Pythinker Code CLI user documentation after meaningful code changes that affect product behavior or user experience.

Convert Markdown files to Word documents (.docx) with proper formatting, Chinese font support (FangSong for all text including headings), black font color, 1.5x line spacing, precise first-line indent (24pt), heading spacing after (1 line), no italic headings, and automatic superscript conversion for citation numbers. Use when converting .md files to .docx, creating Word documents from markdown, or when user mentions Word, DOCX, or document conversion. Requires pandoc.

Therapeutics Data Commons. Conjuntos de dados prontos para IA em descoberta de drogas (ADME, toxicidade, DTI), benchmarks, divisões de scaffold, oráculos moleculares, para ML terapêutico e predição farmacológica.

NIH grant research skill for clinical researchers. Grill-me intake (research idea + career stage + preliminary data + environment + submission posture + known institute targets) locks down the funding strategy before any search runs. Runs a 5-facet Consensus positioning analysis (with draft Significance/Innovation language), maps the research to the right NIH institutes and study sections via RePORTER, finds NOSIs and funded overlap, and produces an editable Word document (.docx) with budget/scope-aware mechanism recommendations, submission timelines, and a mandatory program officer recommendation. Use when the user asks about research funding or makes any grant-related request (e.g., 'grants for [topic]', 'find grants for my research idea', 'what grants match my research', 'help me find NIH funding', 'grant opportunities for my research'). NIH-only scope — non-NIH funders (PCORI, DOD CDMRP, VA, foundations) are out of scope and flagged at intake.

Generates a strategic NIH funding overview as an editable .docx file, including research positioning analysis, institute mapping, targeted grant discovery, and strategic recommendations for clinical researchers.

Extract project vision and decisions from a user through iterative Q&A, then convert them into clear repo documentation (README, ADRs, lessons). Use when user asks to document ideas in their head.

MindOS 是用户的本地知识助手，也是跨会话、跨 Agent 共享的知识库。它保存决策记录、会议纪要、SOP、 排错经验、架构选型、调研结论和偏好设置。 仅 mindRoot 知识库内任务。不用于：改代码仓库、项目源码、KB 外路径。 核心概念：空间、指令(INSTRUCTION.md)、技能(SKILL.md)；笔记可承载指令与技能。 触发场景：保存或记录任何内容、搜索历史笔记或上下文、更新或编辑文件、整理或重组文件结构、 执行SOP或工作流、捕获对话中的决策、复盘或总结经验、追加表格或CSV数据、跨Agent交接上下文、 提炼经验教训、同步关联文档、查找之前是否讨论过某事、查询历史决策、查找模板或SOP、 为会议准备上下文、快速暂存到暂存台、整理暂存台、知识健康检查、检测知识冲突或矛盾、 查找过期内容。 触发词：帮我记下来、搜一下我的笔记、更新知识库、整理文件、执行工作流、保存到知识库、 记录一下、整理笔记、复盘、提炼经验、同步文档、查一下之前的记录、有没有相关的笔记、 我之前写过什么、把这个存起来、总结一下保存、交接给其他Agent、追加到表格、 放到暂存台、整理暂存台、知识健康检查、检测知识冲突。 主动行为——不要等用户提到 MindOS： (1) 用户的问题暗示可能存在历史记录（过去的决策、之前的讨论、会议纪要）→ 先搜 MindOS， 即使没有明确提到知识库。 (2) 完成有价值的工作后（修了 bug、做了决策、总结了经验、选定了架构、开完了会）→ 主动提议保存到 MindOS，方便以后查阅。 (3) 经历了较长或多主题的对话后 → 建议把关键决策和上下文持久化。

Therapeutics Data Commons. AI-ready drug discovery datasets (ADME, toxicity, DTI), benchmarks, scaffold splits, molecular oracles, for therapeutic ML and pharmacological prediction.

Create C4 architecture diagrams at context, container, and component levels with Mermaid syntax, including templates and styling tips.

Grilling session that challenges your plan against the existing domain model, sharpens terminology, and updates documentation (CONTEXT.md, ADRs) inline as decisions crystallise. Use when user wants to stress-test a plan against their project's language and documented decisions.

We need to output a SKILL.md file with the specified format.

Access ClinPGx pharmacogenomics data (the successor to PharmGKB) to query gene-drug interactions, CPIC/DPWG dosing guidelines, drug labels, and pharmacogene records. Use when interpreting pharmacogenes (CYP2D6, CYP2C19, TPMT, DPYD, SLCO1B1), looking up genotype-guided drug dosing, checking PGx drug-safety associations (e.g. HLA-B*57:01 and abacavir), or supporting precision medicine and clinical pharmacogenomics decisions. For star-allele definitions/frequencies see PharmVar; for germline/somatic variant pathogenicity see alterlab-clinvar. Part of the AlterLab Academic Skills suite.

钉钉文档（adoc）：创建、读取、编辑、块、评论、附件、导出、版本及Markdown/JSONML写入。原生 .md→dingtalk-misc；文件→dingtalk-drive；知识库→dingtalk-wiki；axls→dingtalk-misc，able→dingtalk-aitable。

Predicts the highest-impact next action for your project by running a 5-agent meta-DAG pipeline. Gathers project signals automatically (git, recent files, port-daddy, CLAUDE.md), then runs sensemaker → decomposer → skill-selector + premortem → synthesizer. When execution is approved, convert each predicted node into a skillful node prompt using skillful-node-prompt + skillful-subagent-creator, prefer live WinDAGs visualization backed by POST /api/execute and /ws/execution/:id, and fall back to ASCII only when live visualization is unavailable. Activate on: "what should I do", "what's next", "next move", "/next-move", "where should I focus", "what's the highest impact thing right now". NOT for: creating skills, debugging one specific bug, or promising topology-specific runtime behavior the current server cannot execute.

Draft a legal document — a pleading, motion, brief section, or contract clause — with verified citations, flagged assumptions, and mandatory supervisor review before filing.

Interact with Paddock — AI agent orchestration dashboard. Use when registering agents, managing tasks, syncing skills, or querying agent/task status via Paddock APIs.

Scaffolds and operates an Obsidian-based blog content brain dual-optimized for Google rankings and AI citations, covering writing, editorial strategy, and fact-checking.