Results for “clinpgx”

Queries the ClinPGx REST API for pharmacogenomic gene-drug data, clinical annotations, CPIC guidelines, and FDA drug labels, generating markdown reports with CSV tables.

Access ClinPGx pharmacogenomics data (the successor to PharmGKB) to query gene-drug interactions, CPIC/DPWG dosing guidelines, drug labels, and pharmacogene records. Use when interpreting pharmacogenes (CYP2D6, CYP2C19, TPMT, DPYD, SLCO1B1), looking up genotype-guided drug dosing, checking PGx drug-safety associations (e.g. HLA-B*57:01 and abacavir), or supporting precision medicine and clinical pharmacogenomics decisions. For star-allele definitions/frequencies see PharmVar; for germline/somatic variant pathogenicity see alterlab-clinvar. Part of the AlterLab Academic Skills suite.

Make the base agentic-skills available in a project by installing them project-local with npx skillpacks init, report and fix skill-install drift, clean up legacy user-home installs, and run guided setup for project-local domain packs. Use when Codex needs to enable base skills for a project, repair stale installs, confirm initialization status, remove old global installs, or set up and route domain packs.

Use for writing, reviewing, debugging, testing, or optimizing Python CVXPY optimization models. Trigger on Variable, Parameter, Expression, Constraint, Objective, Problem, DCP, DPP, DGP, DQCP, solver selection/status, dual values, mixed-integer, cone, or repeated parametric solves. Do not use for scipy.optimize-only, PyMC inference, symbolic algebra without optimization, or hand-written solver implementations.

Generate polished code snippet images with syntax highlighting, supporting PNG, SVG, and WebP exports via the snipgrapher CLI.

Use for writing, reviewing, debugging, testing, or optimizing Python SymPy symbolic mathematics. Trigger on Symbol, assumptions, Expr, Eq, solve/solveset, simplify, factor, expand, calculus, matrices, exact arithmetic, lambdify, code generation, or symbolic-to-numeric conversion. Do not use for NumPy-only arrays, mpmath-only arbitrary-precision numerics, CVXPY optimization models, or parsing untrusted mathematical text.

Identifies a medication from a photo and generates a genotype-informed dosage card using CPIC guidelines and real 23andMe data.

Submit TAO jobs to Lepton managed GPU compute on DGX Cloud, with run/status/cancel interface and multi-node distributed training support.

Model and solve LP, MILP, and QP problems using NVIDIA cuOpt's GPU-accelerated solver via Python, C/C++, or CLI interfaces.

Generates creative launch blueprints for memecoins on pump.fun, including names, symbols, narratives, visual themes, and buyback strategies, with safety guardrails and mandatory disclaimers.

GPG (GNU Privacy Guard) encryption and signing reference. Covers key generation (Ed25519/RSA), export/import, keyservers, file encryption (symmetric + asymmetric), git commit signing, detached signatures, gpg-agent caching, SSH via GPG, and pass password manager.

MCP registry steward for Claude and Codex. Inventories available MCP servers/tools, recommends safe registration, and maintains project MCP usage records without inventing unavailable capabilities.

Comprehensive toolkit for creating, analyzing, and visualizing complex networks and graphs in Python. Use when working with network/graph data structures, analyzing relationships between entities, computing graph algorithms (shortest paths, centrality, clustering), detecting communities, generating synthetic networks, or visualizing network topologies. Applicable to social networks, biological networks, transportation systems, citation networks, and any domain involving pairwise relationships.

Manage Kafka consumer groups on Redpanda with rpk group: list, describe, seek, delete groups, and delete offsets.

Open Neural Network Exchange format for model interoperability across frameworks. Export models from PyTorch, TensorFlow, and other frameworks to ONNX, optimize with ONNX Runtime, and deploy for cross-platform inference on CPU, GPU, and edge devices.

Configures, troubleshoots, and extends NPSP Customizable Rollups, including rollup definitions, filter groups, batch job modes, and migration from legacy rollups.

GPG (GNU Privacy Guard) encryption and signing reference. Covers key generation (Ed25519/RSA), export/import, keyservers, file encryption (symmetric + asymmetric), git commit signing, detached signatures, gpg-agent caching, SSH via GPG, and pass password manager.

Route plain-language requests for Claude Code, Cursor, Copilot, MarketingClaw ACP, OpenCode, Gemini CLI, Qwen, Kiro, Kimi, iFlow, Factory Droid, Kilocode, or explicit ACP harness work into either MarketingClaw ACP runtime sessions or direct acpx-driven sessions ("telephone game" flow). For coding-agent thread requests, read this skill first, then use only `sessions_spawn` for thread creation. Codex chat binding defaults to the native Codex app-server plugin unless ACP is explicit or background spawn needs ACP.

Produces NetworkX code with explicit graph kind, node identity, edge multiplicity, direction, attribute schema, weight semantics, and algorithm preconditions, including testing.

Use when processing raw FASTQ files for quality control, adapter trimming, length or complexity filtering, polyG tail trimming, or generating QC reports before downstream analysis.

Simulates BGP hijacking attacks in isolated lab environments to test RPKI deployment, route origin validation, and BGP monitoring defenses against prefix hijacking and route leak attacks.

Use when users ask to discover, install, list, check, update, remove, back up, restore, sync, or initialize Agent Skills, mention `bunx skills`, `npx skills`, `skills.sh`, or `skills-lock.json`, ask "find a skill for X", or want help extending agent capabilities with installable skills.

Canonical kip knowledge-store patterns for any process or agent: recall prior facts before work, assert decisions/gate outcomes/rejections as structured facts after work, resolve entities with explicit --model sonnet, and invoke the CLI Windows-safely via node packages/kip-sdk/dist/cli/kip.js when kip is not on PATH.

Navigate, manage, and optimize monorepos with tools like Turborepo, Nx, pnpm workspaces, and Lerna. Enables cross-package impact analysis, selective builds and tests, remote caching, dependency graph visualization, and structured multi-repo to monorepo migrations.

Scan container images for known vulnerabilities using Anchore Grype with SBOM-based matching and configurable severity thresholds.

Use acpx as a headless ACP CLI for agent-to-agent communication, always inside an isolated SubAgent. Use when running coding agents through acpx, managing persistent ACP sessions, queueing prompts, consuming structured agent output from scripts, comparing the same prompt across multiple agents, or composing multi-agent workflows with defineFlow/decision/decisionEdge. Never invoke the claude adapter (nested-instance blacklist).

编写、修改、审查 .cnb.yml 流水线配置，诊断构建失败原因并优化性能。

Globus CLI workflow for staging HuBMAP CODEX datasets from remote endpoints to HiPerGator

Codex Pet generator on RunComfy. Build a Codex-compatible Codex Pet spritesheet.webp + pet.json from a single reference image, drop it into `${CODEX_HOME:-$HOME/.codex}/pets/<name>/` and Codex picks it up as a custom Codex Pet next to the 8 built-ins. This skill produces the exact Codex Pet atlas Codex expects (1536x1872 PNG/WebP, 8 cols x 9 rows, 192x208 cells, 9 animation states — idle, running-right, running-left, waving, jumping, failed, waiting, running, review). Calls OpenAI GPT Image 2 edit ONCE via the local RunComfy CLI as `runcomfy run openai/gpt-image-2/edit` to produce a canonical Codex Pet pose, then assembles all 9 animation rows programmatically with ImageMagick micro-transforms — no Codex Pro, no `$imagegen`, no OPENAI_API_KEY required, only RUNCOMFY_TOKEN. Triggers on "codex pet", "create codex pet", "make codex pet", "hatch codex pet", "/hatch image", "desktop pet codex", "codex pets", "spritesheet.webp", or any explicit ask to build a custom pet for OpenAI Codex.

Gerencia chamados, ativos, projetos e base de conhecimento no GLPI via MCP, com triagem, followups, solução e validações.

Use when user needs capabilities Claude lacks (image generation, real-time X/Twitter data) or explicitly requests external models ("blockrun", "use grok", "use gpt", "dall-e", "deepseek")

NIH grant research skill for clinical researchers. Grill-me intake (research idea + career stage + preliminary data + environment + submission posture + known institute targets) locks down the funding strategy before any search runs. Runs a 5-facet Consensus positioning analysis (with draft Significance/Innovation language), maps the research to the right NIH institutes and study sections via RePORTER, finds NOSIs and funded overlap, and produces an editable Word document (.docx) with budget/scope-aware mechanism recommendations, submission timelines, and a mandatory program officer recommendation. Use when the user asks about research funding or makes any grant-related request (e.g., 'grants for [topic]', 'find grants for my research idea', 'what grants match my research', 'help me find NIH funding', 'grant opportunities for my research'). NIH-only scope — non-NIH funders (PCORI, DOD CDMRP, VA, foundations) are out of scope and flagged at intake.

Use for writing, reviewing, debugging, testing, or analyzing Python SimPy discrete-event simulations. Trigger on Environment, Event, Process, timeout, Resource, PriorityResource, PreemptiveResource, Container, Store, queues, interrupts, simulation clocks, replications, or SimPy monitoring. Do not use for asyncio services, wall-clock schedulers, continuous ODE solvers, or Monte Carlo code without an event-process model.

GPU-accelerated correlation matrix computation with persistent SQLite caching to eliminate bottleneck at correlation calculation during symbol selection

Garbage collection for your Claude Code configuration. Periodically scans ~/.claude (skills, memory, hooks, permissions, MCP servers, caches) for redundant, stale, orphaned, or low-value items, then walks the user through a confirm-each-deletion cleanup. Use when the user says "clean up my config", "config GC", "too many skills", "audit my setup", "my .claude is bloated", or asks for a periodic config review.