Results for “mdr”

EU MDR 2017/745 compliance specialist for medical device classification, technical documentation, clinical evidence, and post-market surveillance. Covers Annex VIII classification rules, Annex II/III technical files, Annex XIV clinical evaluation, and EUDAMED integration.

Decide when and how to assess minimal residual disease (MRD) in multiple myeloma — bone marrow MRD by next-generation flow (NGF) or sequencing (NGS), plus imaging MRD by PET-CT — and how to act on the result. Trigger when a clinician asks "how to assess MRD in myeloma", "MRD-negative complete response", "PET-CT for MRD", "is bone marrow MRD enough", "when to test for MRD", "next-generation flow for myeloma", or "myeloma sustained MRD negativity". Based on EHA-ESMO 2021.

Machine learning development agent for end-to-end ML workflows: data preprocessing, model training, evaluation, hyperparameter tuning, and deployment

Stress-tests a plan against the project's domain model and documented decisions, sharpening terminology and updating DOMAIN.md and ADRs inline as decisions crystallize.

Transform verbose documentation into concise, example-driven tldr command references following the tldr-pages project standards.

Generates synthetic body MRI volumes using NVIDIA's NV-Generate-CTMR rflow-mr model. Wraps the upstream diffusion inference pipeline with config staging, output validation, and NIfTI volume summarization.

Provides practical guidance for training Mixture-of-Experts Vision-Language Models in Megatron Bridge, comparing FSDP and 3D-parallel approaches with lessons from recent multimodal experiments.

Update docs/index.md and write Google-style docstrings for NeMo-RL documentation changes.

Finetunes the NV-Generate-CTMR MR-brain diffusion UNet from user-supplied NIfTI training volumes using a wrapper that stages configs and delegates to upstream scripts.

Runs a relentless interview that sharpens a plan or design and creates docs (ADRs and glossary) along the way. Use when the user wants to stress-test a plan or design, or produce decision records.

Grilling session that challenges your plan against the existing domain model, sharpens terminology, and updates documentation (CONTEXT.md, ADRs) inline as decisions crystallise. Use when user wants to stress-test a plan against their project's language and documented decisions.

Access the Human Metabolome Database (HMDB, 220K+ metabolites), searching by name, HMDB ID, or structure to retrieve chemical properties, biomarker data, NMR/MS reference spectra, and associated pathways. Use when identifying a human metabolite, looking up its biomarker or disease associations, matching NMR/MS spectra, or running metabolomics annotation. Part of the AlterLab Academic Skills suite.

Creates and manages Architecture Decision Records using the Michael Nygard format, including new ADR creation, retrospective analysis, superseding, deprecating, and index generation.

Maintains a project's domain vocabulary and records architecturally-significant decisions as they're made — a CONTEXT.md glossary and gated ADRs, not passive documentation read once. Use when terminology conflicts or turns fuzzy, when making a decision that's hard to reverse/surprising/a real trade-off, or when a stated domain rule doesn't match what the code actually does.

Perform digital rectal examination (DRE) in all men before initiating testosterone therapy to exclude prostate abnormalities or support suspicion of hypogonadism when prostate volume is reduced. Triggered when a clinician considers starting testosterone and questions whether a prostate exam is needed first or whether to check the prostate before prescribing TTh.

Converts long-form markdown documents (specs, RFCs, reports, plans) into a single-file HTML page with sticky table of contents, scrollspy, search filter, code-copy buttons, and customizable design tokens.

Read every ADR markdown file in docs/adr before making or reviewing decision-sensitive changes. Use when architecture, conventions, or tradeoffs are involved.

Use this skill when selecting an MRO for drug testing program oversight. Covers MRO qualifications under Part 40, what the MRO does, and how to evaluate MRO services.

Grilling session that challenges your plan against the existing domain model, sharpens terminology, and updates documentation (CONTEXT.md, ADRs) inline as decisions crystallise. Use when user wants to stress-test a plan against their project's language and documented decisions.

Grilling session that challenges your plan against the existing domain model, sharpens terminology, and updates documentation (CONTEXT.md, ADRs) inline as decisions crystallise. Use when user wants to stress-test a plan against their project's language and documented decisions.

Comprehensive guide to mdp. Master the concepts, implementation, best practices, and real-world applications of mdp in professional environments.

Experimental methodology and statistical rigor specialist. Use when the user asks to talk to Breach, requests the methodologist, or needs experiment design review, ablation planning, and reproducibility protocols.

Decide where to save any piece of information — monday.com, local file, daily notes, or MEMORY.md. Use this skill before saving anything to ensure the right destination. Prevents local clutter and ensures the owner can access all relevant content in monday.com.

Explains MariaDB-specific behavior of DROP USER and RENAME USER, including multiple accounts per statement, IF EXISTS handling, active-connection warnings, and effects on privileges and definers. Use when writing or reviewing account-lifecycle SQL for MariaDB.

Fetches MDN Web Docs content via the Yari API and search index, including browser compatibility data, Web API references, and CSS property documentation, with offline lookups using the BCD npm package.

This skill recommends monitoring desmopressin (DDAVP) doses and adjusting them as needed in patients who have recently started antiepileptic drugs (AEDs). It is triggered when a patient initiates AED therapy and requires DDAVP management for diabetes insipidus.

Runs a structured interview that stress-tests a plan against the project's domain model, sharpens terminology, and updates CONTEXT.md and ADRs inline as decisions are made.

Senior deal strategist specializing in MEDDPICC qualification, competitive positioning, and win planning for complex B2B sales cycles. Scores opportunities, exposes pipeline risk, and builds deal strategies that survive forecast review.

Extract project vision and decisions from a user through iterative Q&A, then convert them into clear repo documentation (README, ADRs, lessons). Use when user asks to document ideas in their head.

Interdisciplinary synthesis and cross-domain transfer specialist. Use when the user asks to talk to Astra, requests the synthesizer, or needs cross-field insight connections and multi-modal research directions.

Responds to malware infections across enterprise endpoints by identifying the malware family, determining infection vectors, assessing spread, and executing eradication procedures.

Matryoshka Representation Learning

Converts a markdown deck into a single-file HTML presentation with keyboard navigation, presenter mode, and print-to-PDF support.

Documents MariaDB-specific INSERT syntax and behavior, including RETURNING, ON DUPLICATE KEY UPDATE, INSERT IGNORE, and various forms and modifiers, to help write and review INSERT statements.