Results for “pcre2”

Automates genome-wide association studies from genotype files to publication-ready results, running PLINK2 QC and REGENIE regression with Manhattan and QQ plots.

Imported skill reference from anthropic

Determines if PAC/PRA ratio and PAC levels indicate positive or provisionally positive screening for primary aldosteronism. Triggered when a clinician has PAC and PRA results and asks “Is this screening test positive for PA?” or needs to interpret borderline results.

Build a scalable outbound B2B sales machine with specialized SDR, AE, and CSM roles, using Cold Calling 2.0, referral emails, ANUM qualification, and pipeline math to generate predictable revenue.

Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.

Run differential gene expression analysis on bulk RNA-seq count matrices with PyDESeq2, the Python port of DESeq2 — size-factor normalization, dispersion estimation, Wald tests, FDR (Benjamini-Hochberg) correction, and volcano/MA plots. Use when identifying differentially expressed genes between conditions from raw bulk RNA-seq counts. Part of the AlterLab Academic Skills suite.

Deploy and operate CAPEv2 sandbox for automated malware analysis with behavioral monitoring, payload extraction, configuration parsing, and anti-evasion capabilities.

Provides a command-line workflow for binary analysis with radare2, covering reconnaissance, disassembly, function analysis, string and import inspection, patching, binary diffing, and r2pipe scripting across PE, ELF, Mach-O, DEX, and WASM formats.

Systematic audit and review by Referee 2. Two modes — "deck" reviews slide presentations for rhetoric, visual quality, and compile cleanliness; "code" performs cross-language replication and econometric audit of empirical pipelines. Use when reviewing slides, auditing code, or verifying replication.

Perform differential gene expression analysis for bulk RNA-seq data using PyDESeq2, supporting formulaic designs, Wald tests, FDR correction, LFC shrinkage, and result visualization.

Calculate polygenic risk scores from direct-to-consumer genetic data using published scoring files from the PGS Catalog and contextualize results against population reference distributions.

Cross-runtime 2-stage pipeline for Claude Code, Codex/OMX, and Gemini/Antigravity/OMA: trace causal hypotheses, inject evidence into deep-interview style requirements crystallization, then hand off to the right runtime planner/executor.

Computes evidence-aware polygenic risk scores from local VCF or WGS files using the just-prs engine and a pinned local MCP server, with honest interpretation and model comparison.

Recommends ACE inhibitors, ARBs, or calcium channel blockers as first-line hypertension therapy rather than β‑adrenergic blockers in obese patients with type 2 diabetes. Triggers include when a clinician asks, 'What antihypertensive should I start for this obese patient with T2DM to avoid weight gain?' or 'Should I avoid β‑blockers in this patient with diabetes and hypertension?'

`task-agent`/`review-agent`: use when CPU, memory, I/O, database, network, rendering, or cost needs measured bottleneck evidence; skip without a profiling need.

Guides end-to-end testing of frontend applications using Playwright or Cypress, covering multi-page user flows in real browsers, API mocking, and CI integration.

Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.

Citrea: first ZK-rollup on Bitcoin (mainnet 27 Jan 2026), zkEVM, BitVM2 trustless bridge, ctUSD stablecoin, native BTC lending. USE WHEN: building zkEVM apps on Bitcoin, integrating with Citrea, evaluating ZK rollups vs sidechains.

MaxFuse parameter tuning for datasets with large protein:RNA cell ratios (>100:1)

Production-grade Playwright testing toolkit. Use when the user mentions Playwright tests, end-to-end testing, browser automation, fixing flaky tests, test migration, CI/CD testing, or test suites. Generate tests, fix flaky failures, migrate from Cypress/Selenium, sync with TestRail, run on BrowserStack. 55 templates, 3 agents, smart reporting.

Prepare PRINCE2 Closing a Project material: product acceptance, end project report, lessons report, benefits review plan, handover, follow-on actions, and closure recommendation.

Prepare PRINCE2 Directing a Project gate briefs for project board decisions, including initiation authorization, stage authorization, exception decisions, and closure authorization.

Run PRINCE2 Controlling a Stage: work package tracking, highlight reports, risk and issue control, tolerance checks, change handling, and corrective action planning.

Evaluates likelihood of primary aldosteronism by measuring plasma aldosterone suppression after oral captopril; normal suppression ≥30% makes PA unlikely, while lack of suppression with persistently suppressed plasma renin activity suggests PA. Use when assessing captopril challenge test (CCT) results for PA diagnosis in patients with positive aldosterone-to-renin ratio.

ORCA v2.0 — Gen-2 Striker with momentum event quality confirmation. FIRST_JUMP detection enhanced with Tier 2 momentum events and TCS trader quality tags. Stalker permanently removed. DSL exit managed by plugin runtime via runtime.yaml.

Performance Profiler

Systematically deobfuscate multi-layer PowerShell malware using AST analysis, dynamic tracing, and tools like PSDecode and PowerDecode to reveal hidden payloads and C2 infrastructure.

2-stage pipeline: trace (causal investigation) -> deep-interview (requirements crystallization) with 3-point injection

Perform causal interventions on PyTorch models using pyvene's declarative framework for causal tracing, activation patching, and interchange intervention training.

Harness E2E

Analyze URLs or text to discover ranked Polymarket, Hyperliquid, and Deribit markets with Quotient edge scores, paid via on-chain x402 settlement.

Diagnose frame-rate bottlenecks (CPU vs GPU bound FIRST), control Unreal Insights traces, sample live frame times, and annotate performance captures. Use when FPS is low/bad, the game is slow, or you need to find what is limiting the frame rate.

Provides guidance for performing causal interventions on PyTorch models using pyvene's declarative intervention framework. Use when conducting causal tracing, activation patching, interchange intervention training, or testing causal hypotheses about model behavior.

Infer gene regulatory networks (GRNs) from expression matrices using arboreto's scalable GRNBoost2 and GENIE3 tree-ensemble algorithms with Dask-distributed computation. Use when analyzing bulk or single-cell RNA-seq transcriptomics to map transcription-factor-to-target-gene regulatory interactions, build adjacency networks, or run the GRN-inference step of a SCENIC pipeline on large datasets. Part of the AlterLab Academic Skills suite.

Interprets the aldosterone-to-renin ratio using active renin concentration (ARC) to screen for primary aldosteronism. Triggered when a clinician has PAC and ARC results and asks 'How do I interpret this ARR using active renin concentration?'