1---2name: leads-literature-mining3description: <!--4---5<!--6# COPYRIGHT NOTICE7# This file is part of the "Universal Biomedical Skills" project.8# Copyright (c) 2026 MD BABU MIA, PhD <md.babu.mia@mssm.edu>9# All Rights Reserved.10#11# This code is proprietary and confidential.12# Unauthorized copying of this file, via any medium is strictly prohibited.13#14# Provenance: Authenticated by MD BABU MIA1516-->1718---19name: leads-literature-mining20description: Review Automator21keywords:22 - literature-mining23 - systematic-review24 - meta-analysis25 - pubmed26 - evidence-synthesis27measurable_outcome: Complete a systematic review screen of 100+ papers with >90% inclusion/exclusion accuracy compared to human baseline.28license: CC-BY-4.029metadata:30 author: Nature Communications 202531 version: "1.0.0"32compatibility:33 - system: Python 3.9+34allowed-tools:35 - run_shell_command36 - web_fetch37---3839# LEADS (Literature Mining Agent)4041A specialized LLM agent for automating systematic reviews and meta-analyses, capable of high-accuracy study selection and data extraction.4243## When to Use4445* **Systematic Reviews**: Screening thousands of abstracts for inclusion criteria.46* **Data Extraction**: Pulling specific metrics (e.g., hazard ratios, sample sizes) from full-text PDFs.47* **Evidence Synthesis**: Aggregating findings across multiple studies.4849## Core Capabilities50511. **Study Selection**: Automated screening based on PICO criteria.522. **Data Extraction**: Structured extraction of study characteristics and results.533. **Quality Assessment**: Risk of bias evaluation.5455## Workflow56571. **Search**: Query PubMed/Embase.582. **Screen**: Apply inclusion/exclusion criteria to abstracts.593. **Extract**: Parse full text for data points.604. **Report**: Generate PRISMA flow diagram and evidence table.6162## Example Usage6364**User**: "Perform a systematic review on the efficacy of CAR-T in solid tumors."6566**Agent Action**:67```bash68python -m leads.review --topic "CAR-T solid tumors" --criteria ./criteria.json69```707172<!-- AUTHOR_SIGNATURE: 9a7f3c2e-MD-BABU-MIA-2026-MSSM-SECURE -->
Run npx skillmds@latest add biotender-max/leads-literature-mining in your terminal (requires Node.js), paste this page's agent-chat prompt into Claude, Cursor, or any MCP-connected agent, or download the SKILL.md file and copy it into your agent's skills directory.
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BioTender-max (@biotender-max) published this skill. Their other Agent Skills are listed on their SkillMD profile.