Interpreting Cardiac Catheterization
Structures cath lab report interpretation with hemodynamics, angiographic findings, and intervention documentation.
Why This Skill Exists
Cardiac catheterization remains the gold standard for coronary artery disease assessment and the definitive hemodynamic evaluation tool. Misinterpretation of coronary angiography — underestimating a left main lesion, failing to recognize FFR-significant stenosis, or missing anomalous coronary anatomy — can lead to inappropriate revascularization decisions or lethal delays. Similarly, hemodynamic data from right and left heart catheterization drives critical decisions in valvular disease, pulmonary hypertension, cardiomyopathy, and shock management.
The SCAI (Society for Cardiovascular Angiography and Interventions) and ACC mandate structured reporting of catheterization findings. This skill enforces systematic documentation of hemodynamics, coronary anatomy, lesion severity, intervention details, and complications.
Checkpoint A: Pre-Draft Intake (Mandatory)
- What was the indication for catheterization — ACS, stable angina, preoperative, valvular evaluation, hemodynamic assessment, or cardiomyopathy workup? (default: "Indication not specified")
- Was this a diagnostic catheterization only, or was PCI performed? (default: "Diagnostic only")
- Was right heart catheterization (RHC) performed in addition to left heart? (default: "LHC only")
- What is the patient's baseline renal function (Cr, eGFR)? (default: "Not provided — flag contrast nephropathy risk")
- Were any prior catheterizations performed? (default: "No prior cath available")
- Are prior non-invasive stress test or imaging results available? (default: "Not provided")
- What vascular access was used — radial, femoral, or other? (default: "Not specified")
Documents to Request
- Full catheterization report with angiographic images
- Hemodynamic tracings (pressure waveforms)
- Prior catheterization reports for comparison
- Non-invasive testing results (stress echo, nuclear, CCTA)
- Echocardiogram (for valve correlation)
- Current medication list (antiplatelet, anticoagulant)
- Labs: BMP, CBC, coagulation studies, troponin trend if ACS
Step 1: Hemodynamic Data Interpretation
Normal Resting Hemodynamic Values:
| Parameter |
Normal Range |
| RA mean |
0–8 mmHg |
| RV systolic/diastolic |
15–30 / 0–8 mmHg |
| PA systolic/diastolic/mean |
15–30 / 4–12 / 9–18 mmHg |
| PCWP (mean) |
4–12 mmHg |
| LV systolic/EDP |
100–140 / 4–12 mmHg |
| Aortic systolic/diastolic/mean |
100–140 / 60–90 / 70–105 mmHg |
| Cardiac output (Fick) |
4.0–8.0 L/min |
| Cardiac index |
2.5–4.0 L/min/m² |
| SVR |
800–1200 dynes·s/cm⁵ |
| PVR |
< 3 Wood units (< 240 dynes·s/cm⁵) |
Key Hemodynamic Calculations:
- Cardiac output (Fick) = VO₂ / (1.36 × Hgb × 10 × [SaO₂ − SvO₂])
- SVR = (MAP − RAP) × 80 / CO
- PVR = (mPAP − PCWP) × 80 / CO
- Valve area (Gorlin formula): AVA = CO / (44.3 × SEP × HR × √mean gradient)
Hemodynamic Pattern Recognition:
| Pattern |
RA |
PCWP |
CO/CI |
Diagnosis |
| ↑ RA, ↑ PCWP, ↓ CO |
High |
High |
Low |
Cardiogenic shock |
| ↑ RA, normal PCWP, ↓ CO |
High |
Normal |
Low |
RV failure / PE / tamponade |
| Equalization of diastolic pressures |
RA ≈ RVDP ≈ PADP ≈ PCWP |
— |
Low |
Constrictive pericarditis or tamponade |
| ↑ PCWP with V waves |
Normal-high |
V wave > 2× mean PCWP |
Variable |
Severe mitral regurgitation |
Step 2: Coronary Angiography Interpretation
Standard Coronary Anatomy Reporting:
- Left main (LM): length, caliber, disease
- Left anterior descending (LAD): proximal, mid, distal segments; diagonal branches (D1, D2)
- Left circumflex (LCx): proximal, distal; obtuse marginal branches (OM1, OM2)
- Right coronary artery (RCA): proximal, mid, distal; posterior descending (PDA), posterolateral (PLV)
- Dominance: right-dominant (85%), left-dominant (8%), co-dominant (7%)
Lesion Severity Classification:
| Severity |
% Stenosis |
Clinical Significance |
| Mild |
1–49% |
Non-obstructive |
| Moderate |
50–69% |
Borderline — consider FFR/iFR |
| Severe |
70–99% |
Obstructive — revascularization candidate |
| Total occlusion |
100% |
CTO — assess collateral supply |
| Left main |
≥ 50% |
Significant by definition |
Physiologic Assessment:
- FFR (fractional flow reserve): ≤ 0.80 = hemodynamically significant
- iFR (instantaneous wave-free ratio): ≤ 0.89 = significant
- IVUS/OCT: used for plaque characterization, stent optimization, left main assessment
Lesion Morphology (ACC/AHA Classification):
- Type A: discrete (< 10 mm), concentric, non-calcified → high PCI success
- Type B1: tubular (10–20 mm), eccentric, moderate calcification → moderate risk
- Type B2: two or more Type B features → higher risk
- Type C: diffuse (> 20 mm), total occlusion, degenerated graft → highest risk
Step 3: PCI Documentation (If Intervention Performed)
Document each intervention with:
- Target vessel and segment
- Lesion characteristics (length, calcification, bifurcation involvement)
- Pre-intervention stenosis percentage
- Guidewire and catheter used
- Pre-dilation details (balloon size, pressure, result)
- Stent deployed (DES type, dimensions, deployment pressure)
- Post-dilation (if performed)
- Final angiographic result (residual stenosis, TIMI flow grade)
- Complications (dissection, perforation, no-reflow, side branch loss)
TIMI Flow Grading:
| Grade |
Definition |
| 0 |
No perfusion — complete occlusion |
| 1 |
Penetration without perfusion — contrast passes but fails to opacify the distal bed |
| 2 |
Partial perfusion — distal bed opacifies but with delayed filling or clearance |
| 3 |
Complete perfusion — normal filling and clearance |
Step 4: Ventriculography and Additional Findings
LV Function by Ventriculography:
- Qualitative: normal, mild/moderate/severe hypokinesis, akinesis, dyskinesis
- LVEF estimation from RAO 30° projection
- Wall motion abnormalities mapped to coronary territories
Additional Assessments:
- Aortography: aortic regurgitation grading (1+ to 4+), aortic root dimensions
- Shunt assessment: step-up in O₂ saturation (Qp:Qs > 1.5 = significant L→R shunt)
- Transplant evaluation: right heart hemodynamics, PVR calculation, vasoreactivity testing
Step 5: Post-Procedure Assessment and Complications
Immediate Post-Cath Monitoring:
- Access site: hematoma, retroperitoneal bleed, pseudoaneurysm, AV fistula
- Renal: contrast-induced nephropathy risk (hydrate; check Cr at 48–72 hours)
- Vascular: limb ischemia if femoral approach, radial artery occlusion
- Cardiac: post-PCI chest pain, stent thrombosis, coronary dissection
Dual Antiplatelet Therapy (DAPT) Post-PCI:
- After DES: aspirin + P2Y12 inhibitor (clopidogrel, ticagrelor, or prasugrel)
- ACS: minimum 12 months DAPT
- Stable CAD: minimum 6 months DAPT (3 months in high bleeding risk)
- Triple therapy (DOAC + DAPT) if concurrent AF: minimize duration; de-escalate to DOAC + single antiplatelet
Checkpoint B: Post-Draft Alignment (Mandatory)
- Are all hemodynamic values documented with normal references?
- Is every coronary artery segment reported with dominance stated?
- For PCI: is the lesion, device, and result fully documented with TIMI flow?
- Are complications assessed and documented or their absence noted?
- Is the post-procedure antiplatelet plan specified with duration?
Quality Audit
Guidelines
- Report coronary dominance in every catheterization interpretation — it affects the clinical significance of RCA vs. LCx lesions.
- Intermediate stenoses (50–69%) should trigger documentation of whether physiologic assessment (FFR/iFR) was performed or planned.
- For left main disease ≥ 50%, always document referral to Heart Team discussion for CABG vs. PCI per ACC/AHA guidelines.
- Hemodynamic waveforms should be correlated with clinical context — giant V waves on PCWP tracing must be reported and correlated with MR severity on echo.
- Contrast volume should be documented and kept below 3–4× eGFR to minimize nephropathy risk.
- When CTO is identified, document the presence and grade of collateral supply (Rentrop classification).
- Post-PCI DAPT duration must account for bleeding risk, ischemic risk, and concurrent anticoagulation needs — document the rationale for chosen duration.
1---2name: interpreting-cardiac-catheterization3description: Structures cath lab report interpretation with hemodynamics, angiographic findings, and intervention documentation. Use when reviewing cath reports, documenting PCI procedures, or interpreting hemodynamic data.4---5
6# Interpreting Cardiac Catheterization
7
8Structures cath lab report interpretation with hemodynamics, angiographic findings, and intervention documentation.
9
10## Why This Skill Exists
11
12Cardiac catheterization remains the gold standard for coronary artery disease assessment and the definitive hemodynamic evaluation tool. Misinterpretation of coronary angiography — underestimating a left main lesion, failing to recognize FFR-significant stenosis, or missing anomalous coronary anatomy — can lead to inappropriate revascularization decisions or lethal delays. Similarly, hemodynamic data from right and left heart catheterization drives critical decisions in valvular disease, pulmonary hypertension, cardiomyopathy, and shock management.
13
14The SCAI (Society for Cardiovascular Angiography and Interventions) and ACC mandate structured reporting of catheterization findings. This skill enforces systematic documentation of hemodynamics, coronary anatomy, lesion severity, intervention details, and complications.
15
16---
17
18## Checkpoint A: Pre-Draft Intake (Mandatory)
19
201. What was the indication for catheterization — ACS, stable angina, preoperative, valvular evaluation, hemodynamic assessment, or cardiomyopathy workup? (default: "Indication not specified")
212. Was this a diagnostic catheterization only, or was PCI performed? (default: "Diagnostic only")
223. Was right heart catheterization (RHC) performed in addition to left heart? (default: "LHC only")
234. What is the patient's baseline renal function (Cr, eGFR)? (default: "Not provided — flag contrast nephropathy risk")
245. Were any prior catheterizations performed? (default: "No prior cath available")
256. Are prior non-invasive stress test or imaging results available? (default: "Not provided")
267. What vascular access was used — radial, femoral, or other? (default: "Not specified")
27
28### Documents to Request
29
30- Full catheterization report with angiographic images
31- Hemodynamic tracings (pressure waveforms)
32- Prior catheterization reports for comparison
33- Non-invasive testing results (stress echo, nuclear, CCTA)
34- Echocardiogram (for valve correlation)
35- Current medication list (antiplatelet, anticoagulant)
36- Labs: BMP, CBC, coagulation studies, troponin trend if ACS
37
38---
39
40## Step 1: Hemodynamic Data Interpretation
41
42**Normal Resting Hemodynamic Values:**
43
44| Parameter | Normal Range |
45|-----------|-------------|
46| RA mean | 0–8 mmHg |
47| RV systolic/diastolic | 15–30 / 0–8 mmHg |
48| PA systolic/diastolic/mean | 15–30 / 4–12 / 9–18 mmHg |
49| PCWP (mean) | 4–12 mmHg |
50| LV systolic/EDP | 100–140 / 4–12 mmHg |
51| Aortic systolic/diastolic/mean | 100–140 / 60–90 / 70–105 mmHg |
52| Cardiac output (Fick) | 4.0–8.0 L/min |
53| Cardiac index | 2.5–4.0 L/min/m² |
54| SVR | 800–1200 dynes·s/cm⁵ |
55| PVR | < 3 Wood units (< 240 dynes·s/cm⁵) |
56
57**Key Hemodynamic Calculations:**
58- Cardiac output (Fick) = VO₂ / (1.36 × Hgb × 10 × [SaO₂ − SvO₂])
59- SVR = (MAP − RAP) × 80 / CO
60- PVR = (mPAP − PCWP) × 80 / CO
61- Valve area (Gorlin formula): AVA = CO / (44.3 × SEP × HR × √mean gradient)
62
63**Hemodynamic Pattern Recognition:**
64
65| Pattern | RA | PCWP | CO/CI | Diagnosis |
66|---------|----|----- |-------|-----------|
67| ↑ RA, ↑ PCWP, ↓ CO | High | High | Low | Cardiogenic shock |
68| ↑ RA, normal PCWP, ↓ CO | High | Normal | Low | RV failure / PE / tamponade |
69| Equalization of diastolic pressures | RA ≈ RVDP ≈ PADP ≈ PCWP | — | Low | Constrictive pericarditis or tamponade |
70| ↑ PCWP with V waves | Normal-high | V wave > 2× mean PCWP | Variable | Severe mitral regurgitation |
71
72---
73
74## Step 2: Coronary Angiography Interpretation
75
76**Standard Coronary Anatomy Reporting:**
77- Left main (LM): length, caliber, disease
78- Left anterior descending (LAD): proximal, mid, distal segments; diagonal branches (D1, D2)
79- Left circumflex (LCx): proximal, distal; obtuse marginal branches (OM1, OM2)
80- Right coronary artery (RCA): proximal, mid, distal; posterior descending (PDA), posterolateral (PLV)
81- Dominance: right-dominant (85%), left-dominant (8%), co-dominant (7%)
82
83**Lesion Severity Classification:**
84
85| Severity | % Stenosis | Clinical Significance |
86|----------|-----------|----------------------|
87| Mild | 1–49% | Non-obstructive |
88| Moderate | 50–69% | Borderline — consider FFR/iFR |
89| Severe | 70–99% | Obstructive — revascularization candidate |
90| Total occlusion | 100% | CTO — assess collateral supply |
91| Left main | ≥ 50% | Significant by definition |
92
93**Physiologic Assessment:**
94- FFR (fractional flow reserve): ≤ 0.80 = hemodynamically significant
95- iFR (instantaneous wave-free ratio): ≤ 0.89 = significant
96- IVUS/OCT: used for plaque characterization, stent optimization, left main assessment
97
98**Lesion Morphology (ACC/AHA Classification):**
99- Type A: discrete (< 10 mm), concentric, non-calcified → high PCI success
100- Type B1: tubular (10–20 mm), eccentric, moderate calcification → moderate risk
101- Type B2: two or more Type B features → higher risk
102- Type C: diffuse (> 20 mm), total occlusion, degenerated graft → highest risk
103
104---
105
106## Step 3: PCI Documentation (If Intervention Performed)
107
108Document each intervention with:
1091. Target vessel and segment
1102. Lesion characteristics (length, calcification, bifurcation involvement)
1113. Pre-intervention stenosis percentage
1124. Guidewire and catheter used
1135. Pre-dilation details (balloon size, pressure, result)
1146. Stent deployed (DES type, dimensions, deployment pressure)
1157. Post-dilation (if performed)
1168. Final angiographic result (residual stenosis, TIMI flow grade)
1179. Complications (dissection, perforation, no-reflow, side branch loss)
118
119**TIMI Flow Grading:**
120| Grade | Definition |
121|-------|-----------|
122| 0 | No perfusion — complete occlusion |
123| 1 | Penetration without perfusion — contrast passes but fails to opacify the distal bed |
124| 2 | Partial perfusion — distal bed opacifies but with delayed filling or clearance |
125| 3 | Complete perfusion — normal filling and clearance |
126
127---
128
129## Step 4: Ventriculography and Additional Findings
130
131**LV Function by Ventriculography:**
132- Qualitative: normal, mild/moderate/severe hypokinesis, akinesis, dyskinesis
133- LVEF estimation from RAO 30° projection
134- Wall motion abnormalities mapped to coronary territories
135
136**Additional Assessments:**
137- Aortography: aortic regurgitation grading (1+ to 4+), aortic root dimensions
138- Shunt assessment: step-up in O₂ saturation (Qp:Qs > 1.5 = significant L→R shunt)
139- Transplant evaluation: right heart hemodynamics, PVR calculation, vasoreactivity testing
140
141---
142
143## Step 5: Post-Procedure Assessment and Complications
144
145**Immediate Post-Cath Monitoring:**
146- Access site: hematoma, retroperitoneal bleed, pseudoaneurysm, AV fistula
147- Renal: contrast-induced nephropathy risk (hydrate; check Cr at 48–72 hours)
148- Vascular: limb ischemia if femoral approach, radial artery occlusion
149- Cardiac: post-PCI chest pain, stent thrombosis, coronary dissection
150
151**Dual Antiplatelet Therapy (DAPT) Post-PCI:**
152- After DES: aspirin + P2Y12 inhibitor (clopidogrel, ticagrelor, or prasugrel)
153- ACS: minimum 12 months DAPT
154- Stable CAD: minimum 6 months DAPT (3 months in high bleeding risk)
155- Triple therapy (DOAC + DAPT) if concurrent AF: minimize duration; de-escalate to DOAC + single antiplatelet
156
157---
158
159## Checkpoint B: Post-Draft Alignment (Mandatory)
160
1611. Are all hemodynamic values documented with normal references?
1622. Is every coronary artery segment reported with dominance stated?
1633. For PCI: is the lesion, device, and result fully documented with TIMI flow?
1644. Are complications assessed and documented or their absence noted?
1655. Is the post-procedure antiplatelet plan specified with duration?
166
167---
168
169## Quality Audit
170
171- [ ] Indication for catheterization clearly stated
172- [ ] Vascular access site and technique documented
173- [ ] Complete hemodynamic data with normal reference ranges
174- [ ] Coronary dominance identified
175- [ ] All coronary arteries and major branches described
176- [ ] Lesion severity quantified (%) for each stenosis
177- [ ] FFR/iFR reported for intermediate lesions (50–70%)
178- [ ] PCI details complete: lesion, equipment, stent specs, final result
179- [ ] TIMI flow grade documented pre- and post-intervention
180- [ ] LV function assessed (by ventriculography or prior echo)
181- [ ] Complications listed or "no complications" explicitly stated
182- [ ] Contrast volume documented (nephropathy risk)
183- [ ] Post-procedure medication plan (DAPT) documented
184- [ ] Comparison with prior catheterization if available
185
186---
187
188## Guidelines
189
1901. Report coronary dominance in every catheterization interpretation — it affects the clinical significance of RCA vs. LCx lesions.
1912. Intermediate stenoses (50–69%) should trigger documentation of whether physiologic assessment (FFR/iFR) was performed or planned.
1923. For left main disease ≥ 50%, always document referral to Heart Team discussion for CABG vs. PCI per ACC/AHA guidelines.
1934. Hemodynamic waveforms should be correlated with clinical context — giant V waves on PCWP tracing must be reported and correlated with MR severity on echo.
1945. Contrast volume should be documented and kept below 3–4× eGFR to minimize nephropathy risk.
1956. When CTO is identified, document the presence and grade of collateral supply (Rentrop classification).
1967. Post-PCI DAPT duration must account for bleeding risk, ischemic risk, and concurrent anticoagulation needs — document the rationale for chosen duration.