Chembl Skill

Operating rules

• Use scripts/rest_request.py for all ChEMBL API calls.
• Use base_url=https://www.ebi.ac.uk/chembl/api/data.
• The script accepts max_items; for activity, mechanism, and text-search collections, start with API limit=10 and max_items=10.
• Single molecule or target lookups usually do not need max_items.
• Re-run requests in long conversations instead of relying on older tool output.
• Treat displayed ... in tool previews as UI truncation, not literal request content.

Execution behavior

• Return concise markdown summaries from the script JSON by default.
• Return the script JSON verbatim only if the user explicitly asks for machine-readable output.
• Prefer these paths: activity.json, molecule/<id>.json, target/<id>.json, mechanism.json, and molecule/search.json.
• Use record_path to target list fields like activities, mechanisms, or molecules.

Input

• Read one JSON object from stdin.
• Required fields: base_url, path
• Optional fields: method, params, headers, json_body, form_body, record_path, response_format, max_items, max_depth, timeout_sec, save_raw, raw_output_path
• Common ChEMBL patterns:
  • {"base_url":"https://www.ebi.ac.uk/chembl/api/data","path":"activity.json","params":{"molecule_chembl_id":"CHEMBL25","limit":10},"record_path":"activities","max_items":10}
  • {"base_url":"https://www.ebi.ac.uk/chembl/api/data","path":"molecule/CHEMBL25.json"}
  • {"base_url":"https://www.ebi.ac.uk/chembl/api/data","path":"molecule/search.json","params":{"q":"imatinib","limit":10},"record_path":"molecules","max_items":10}

Output

• Success returns ok, source, path, method, status_code, warnings, and either compact records or a compact summary.
• Use raw_output_path when save_raw=true.
• Failure returns ok=false with error.code and error.message.

Execution

echo '{"base_url":"https://www.ebi.ac.uk/chembl/api/data","path":"activity.json","params":{"molecule_chembl_id":"CHEMBL25","limit":10},"record_path":"activities","max_items":10}' | python scripts/rest_request.py

References

• No additional runtime references are required; keep the import package limited to this file and scripts/rest_request.py.