Ata Gh Dosing Age

Calculate initial GH replacement dose based on age

STEP 1 — Gather Information

Collect patient age, confirm diagnosis of proven GHD, and assess for contraindications to GH therapy (e.g., active malignancy, uncontrolled diabetes).

STEP 2 — Rule In / Rule Out

If proven GHD is confirmed and no contraindications exist, proceed to dose stratification; otherwise, do not initiate GH replacement.

STEP 3 — Classify or Stratify

Stratify by age: <60 years versus ≥60 years.

STEP 4 — Decide

Prescribe a starting dose of 0.2–0.4 mg/d for patients <60 years or 0.1–0.2 mg/d for patients ≥60 years.

Clinical Guardrails / Mimics / Pitfalls

Do not use GH for athletic performance, avoid initiation in active malignancy, monitor IGF-1 to prevent over-replacement, and avoid dosing adjustments without biochemical assessment.

Concrete Clinical Example

A 58-year-old man with confirmed GHD and no contraindications starts GH at 0.3 mg/d; a 62-year-old woman with confirmed GHD starts at 0.15 mg/d.

Source: Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practice Guideline, Endocrine Society, 2016, https://doi.org/10.1210/jc.2016-2118

TODO: consider adding scripts/calc.py for the ata-gh-dosing-age calculator