How do I install the Endo Statin Therapy T2d Ckd Stages 1 4 skill?

Run npx skillmds@latest add dromlakhani/endo-statin-therapy-t2d-ckd-stages-1-4 in your terminal (requires Node.js), paste this page's agent-chat prompt into Claude, Cursor, or any MCP-connected agent, or download the SKILL.md file and copy it into your agent's skills directory.

Is Endo Statin Therapy T2d Ckd Stages 1 4 safe to use?

This skill has not completed SkillMD's automated safety review yet. Independent scanners report: SkillSpector: PASS, Skill Scanner: PASS. Capability flags: docs only. SkillMD never runs a skill's scripts for you; review the SKILL.md before installing.

Which AI agents work with Endo Statin Therapy T2d Ckd Stages 1 4?

This skill is tagged as working with Claude Code, Claude.ai, OpenAI Codex. SKILL.md is an open format, so most agents that read a skills directory can load it too.

Is Endo Statin Therapy T2d Ckd Stages 1 4 free to use?

Yes. Installing skills from SkillMD is free, and the skill stays under its author's original license.

Who published Endo Statin Therapy T2d Ckd Stages 1 4?

dromlakhani (@dromlakhani) published this skill. Their other Agent Skills are listed on their SkillMD profile.

Endo Statin Therapy T2d Ckd Stages 1 4 by dromlakhani

Name: Endo Statin Therapy T2d Ckd Stages 1 4
Rating: 4.2 (5 reviews)
Author: dromlakhani

Endo Statin Therapy T2d Ckd Stages 1 4

This skill suggests statin therapy irrespective of cardiovascular risk score to reduce cardiovascular risk in adults with type 2 diabetes and CKD stages 1-4 or postrenal transplant. Consider when encountering phrases such as "Patient with T2D and CKD stages 1-4", "T2D with renal transplant", or "Assessing statin need in diabetic kidney disease".

dromlakhani Updated Sep 8, 2026 10 repo stars

File contents

Statin therapy for type 2 diabetes with chronic kidney disease stages 1-4

STEP 1 — Gather Information

Confirm type 2 diabetes diagnosis; determine CKD stage via eGFR and urine albumin-to-creatinine ratio (stages 1-4) or verify postrenal transplant status; assess for contraindications (pregnancy, active liver disease, hypersensitivity).

STEP 2 — Rule In / Rule Out

Rule in if patient has T2D with CKD stages 1-4 or postrenal transplant and no contraindications; rule out if patient has end-stage renal disease requiring dialysis (statin initiation not advised per guideline).

STEP 3 — Classify or Stratify

Select statin based on renal clearance: prefer pitavastatin, pravastatin, or rosuvastatin (partial renal clearance) for dose adjustment; avoid atorvastatin, fluvastatin, lovastatin, simvastatin if hepatic clearance is a concern, though they require no CKD dose adjustment.

STEP 4 — Decide

Initiate statin therapy at guideline-recommended dose (adjust for CKD except atorvastatin/fluvastatin); schedule lipid panel in 4-12 weeks to assess LDL-C response and adherence.

Clinical Guardrails / Mimics / Pitfalls

Do not statin in pregnancy or active liver disease; avoid gemfibrozil combination due to increased myopathy risk; watch for CYP3A4-interacting drugs (e.g., clarithromycin) when using simvastatin, lovastatin, or atorvastatin; remember atorvastatin and fluvastatin need no CKD dose adjustment.

Concrete Clinical Example

A 58-year-old man with T2D, eGFR 45 mL/min/1.73m² (CKD stage 3a), urine ACR 300 mg/g, not on statin, no contraindications. Initiate pravastatin 20 mg daily (dose-adjusted) and recheck LDL-C in 8 weeks.

Source: Lipid Management in Patients with Endocrine Disorders: An Endocrine Society Clinical Practice Guideline, Endocrine Society, 2020, doi:10.1210/clinem/dgaa674

---name: endo-statin-therapy-t2d-ckd-stages-1-4description: This skill suggests statin therapy irrespective of cardiovascular risk score to reduce cardiovascular risk in adults with type 2 diabetes and CKD stages 1-4 or postrenal transplant. Consider when encountering phrases such as "Patient with T2D and CKD stages 1-4", "T2D with renal transplant", or "Assessing statin need in diabetic kidney disease".---# Statin therapy for type 2 diabetes with chronic kidney disease stages 1-4## STEP 1 — Gather InformationConfirm type 2 diabetes diagnosis; determine CKD stage via eGFR and urine albumin-to-creatinine ratio (stages 1-4) or verify postrenal transplant status; assess for contraindications (pregnancy, active liver disease, hypersensitivity).## STEP 2 — Rule In / Rule OutRule in if patient has T2D with CKD stages 1-4 or postrenal transplant and no contraindications; rule out if patient has end-stage renal disease requiring dialysis (statin initiation not advised per guideline).## STEP 3 — Classify or StratifySelect statin based on renal clearance: prefer pitavastatin, pravastatin, or rosuvastatin (partial renal clearance) for dose adjustment; avoid atorvastatin, fluvastatin, lovastatin, simvastatin if hepatic clearance is a concern, though they require no CKD dose adjustment.## STEP 4 — DecideInitiate statin therapy at guideline-recommended dose (adjust for CKD except atorvastatin/fluvastatin); schedule lipid panel in 4-12 weeks to assess LDL-C response and adherence.## Clinical Guardrails / Mimics / PitfallsDo not statin in pregnancy or active liver disease; avoid gemfibrozil combination due to increased myopathy risk; watch for CYP3A4-interacting drugs (e.g., clarithromycin) when using simvastatin, lovastatin, or atorvastatin; remember atorvastatin and fluvastatin need no CKD dose adjustment.## Concrete Clinical ExampleA 58-year-old man with T2D, eGFR 45 mL/min/1.73m² (CKD stage 3a), urine ACR 300 mg/g, not on statin, no contraindications. Initiate pravastatin 20 mg daily (dose-adjusted) and recheck LDL-C in 8 weeks.**Source:** Lipid Management in Patients with Endocrine Disorders: An Endocrine Society Clinical Practice Guideline, Endocrine Society, 2020, doi:10.1210/clinem/dgaa674

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