How do I install the Endo Therapeutic Goal Random Gh 1 skill?

Run npx skillmds@latest add dromlakhani/endo-therapeutic-goal-random-gh-1 in your terminal (requires Node.js), paste this page's agent-chat prompt into Claude, Cursor, or any MCP-connected agent, or download the SKILL.md file and copy it into your agent's skills directory.

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This skill is tagged as working with Claude Code, Claude.ai, OpenAI Codex. SKILL.md is an open format, so most agents that read a skills directory can load it too.

Is Endo Therapeutic Goal Random Gh 1 free to use?

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Who published Endo Therapeutic Goal Random Gh 1?

dromlakhani (@dromlakhani) published this skill. Their other Agent Skills are listed on their SkillMD profile.

Endo Therapeutic Goal Random Gh 1 by dromlakhani

Name: Endo Therapeutic Goal Random Gh 1
Rating: 4.2 (5 reviews)
Author: dromlakhani

Endo Therapeutic Goal Random Gh 1

Suggests using a random GH level <1.0 µg/L as a therapeutic goal to assess biochemical control of acromegaly during follow‑up after surgery or medical therapy. Use when evaluating post‑treatment response, particularly when random GH is measured alongside IGF‑1 to determine if disease is controlled.

dromlakhani Updated Sep 8, 2026 10 repo stars

File contents

Use random GH <1.0 µg/L as therapeutic goal

STEP 1 — Gather Information

Collect the patient's current random GH level, age‑adjusted IGF‑1, details of recent therapy (surgery, medical treatment), and presence of acromegaly‑related symptoms.

STEP 2 — Rule In / Rule Out

Is the random GH level <1.0 µg/L? If yes, proceed to step 3; if no, proceed to step 4 as inadequate control.

STEP 3 — Classify or Stratify

If random GH <1.0 µg/L and age‑adjusted IGF‑1 is within the laboratory‑specific normal range, classify as biochemical control; otherwise classify as inadequate control despite low GH.

STEP 4 — Decide

For biochemical control, continue current therapy and schedule re‑evaluation in 6–12 months; for inadequate control, consider intensifying therapy (e.g., dose adjustment of medical therapy, repeat surgery, or radiotherapy).

Clinical Guardrails / Mimics / Pitfalls

Do not rely on random GH alone for diagnosis (per guideline 1.4); avoid using a single GH measurement during acute illness or stress; ensure the same GH assay is used over time to minimize variability; do not ignore discordant IGF‑1 elevations or persistent symptoms.

Concrete Clinical Example

A 48‑year‑old man 3 months after transsphenoidal surgery has random GH 0.7 µg/L and age‑adjusted IGF‑1 within normal range; he is classified as controlled and continues clinical surveillance every 6 months.

Source: Acromegaly: An Endocrine Society Clinical Practice Guideline, Endocrine Society, 2014, DOI:10.1210/jc.2014-2700

TODO: consider adding scripts/calc.py for the endo-therapeutic-goal-random-gh-1 calculator

---name: endo-therapeutic-goal-random-gh-1description: Suggests using a random GH level <1.0 µg/L as a therapeutic goal to assess biochemical control of acromegaly during follow‑up after surgery or medical therapy. Use when evaluating post‑treatment response, particularly when random GH is measured alongside IGF‑1 to determine if disease is controlled.---# Use random GH <1.0 µg/L as therapeutic goal## STEP 1 — Gather InformationCollect the patient's current random GH level, age‑adjusted IGF‑1, details of recent therapy (surgery, medical treatment), and presence of acromegaly‑related symptoms.## STEP 2 — Rule In / Rule OutIs the random GH level <1.0 µg/L? If yes, proceed to step 3; if no, proceed to step 4 as inadequate control.## STEP 3 — Classify or StratifyIf random GH <1.0 µg/L **and** age‑adjusted IGF‑1 is within the laboratory‑specific normal range, classify as biochemical control; otherwise classify as inadequate control despite low GH.## STEP 4 — DecideFor biochemical control, continue current therapy and schedule re‑evaluation in 6–12 months; for inadequate control, consider intensifying therapy (e.g., dose adjustment of medical therapy, repeat surgery, or radiotherapy).## Clinical Guardrails / Mimics / PitfallsDo not rely on random GH alone for diagnosis (per guideline 1.4); avoid using a single GH measurement during acute illness or stress; ensure the same GH assay is used over time to minimize variability; do not ignore discordant IGF‑1 elevations or persistent symptoms.## Concrete Clinical ExampleA 48‑year‑old man 3 months after transsphenoidal surgery has random GH 0.7 µg/L and age‑adjusted IGF‑1 within normal range; he is classified as controlled and continues clinical surveillance every 6 months.**Source:** Acromegaly: An Endocrine Society Clinical Practice Guideline, Endocrine Society, 2014, DOI:10.1210/jc.2014-2700> **TODO:** consider adding scripts/calc.py for the endo-therapeutic-goal-random-gh-1 calculator

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