How do I install the Endo Vit D Supp High Risk Prediabetes skill?

Run npx skillmds@latest add dromlakhani/endo-vit-d-supp-high-risk-prediabetes in your terminal (requires Node.js), paste this page's agent-chat prompt into Claude, Cursor, or any MCP-connected agent, or download the SKILL.md file and copy it into your agent's skills directory.

Is Endo Vit D Supp High Risk Prediabetes safe to use?

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Which AI agents work with Endo Vit D Supp High Risk Prediabetes?

This skill is tagged as working with Claude Code, Claude.ai, OpenAI Codex. SKILL.md is an open format, so most agents that read a skills directory can load it too.

Is Endo Vit D Supp High Risk Prediabetes free to use?

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Who published Endo Vit D Supp High Risk Prediabetes?

dromlakhani (@dromlakhani) published this skill. Their other Agent Skills are listed on their SkillMD profile.

Endo Vit D Supp High Risk Prediabetes by dromlakhani

Name: Endo Vit D Supp High Risk Prediabetes
Rating: 4.2 (5 reviews)
Author: dromlakhani

Endo Vit D Supp High Risk Prediabetes

Suggests empiric vitamin D supplementation plus lifestyle modification to reduce diabetes progression risk in adults with high-risk prediabetes. Use when a clinician considers vitamin D for patients with prediabetes meeting 2 or more ADA glycemic criteria (fasting glucose, HbA1c, 2‑hour OGTT) to prevent diabetes.

dromlakhani Updated Sep 8, 2026 10 repo stars

File contents

Vitamin D supplementation for high-risk prediabetes

STEP 1 — Gather Information

Assess glycemic status using ADA criteria: fasting plasma glucose 100‑125 mg/dL, HbA1c 5.7‑6.4%, 2‑hour plasma glucose 140‑199 mg/dL after 75‑g OGTT. Count how many of these three criteria are met. Also verify that lifestyle modification (diet, physical activity, weight loss) is being implemented or planned.

STEP 2 — Rule In / Rule Out

Rule in high‑risk prediabetes if the patient meets ≥2 of the ADA glycemic criteria (or has documented impaired glucose tolerance).
Rule out if 0‑1 criteria are met (low‑risk prediabetes) or glucose values are normal; empiric vitamin D supplementation is not recommended for diabetes prevention in this group.

STEP 3 — Classify or Stratify

If high‑risk prediabetes is confirmed, no further stratification by 25(OH)D level is required per guideline; the recommendation applies regardless of baseline vitamin D status. Proceed to decide on supplementation.

STEP 4 — Decide

Initiate empiric vitamin D supplementation (dose not specified; trials used 842‑7543 IU daily, weighted average ≈3500 IU/day) in addition to continuing lifestyle modification. Re‑evaluate glycemic status periodically per usual prediabetes care.

Clinical Guardrails / Mimics / Pitfalls

Do not rely on serum 25(OH)D testing to guide or withhold supplementation in this population.
Avoid high‑dose intermittent bolus regimens without monitoring for hypercalcemia or nephrolithiasis.
Do not use in patients with established indications for vitamin D treatment (e.g., hypocalcemia, renal osteodystrophy) unless those indications are also present.
Do not substitute vitamin D for lifestyle modification; it is adjunctive only.
Do not extrapolate to pregnant individuals, children, or adults ≥75 years without separate indication.

Concrete Clinical Example

A 58‑year‑old man with BMI 31 kg/m² has fasting glucose 112 mg/dL and HbA1c 6.0% (2 ADA criteria met); 2‑hour OGTT is 130 mg/dL. He has been advised on diet and exercise. Decision: Start empiric vitamin D supplementation (e.g., 2000‑3000 IU daily) and reinforce lifestyle modification.

Source: Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline, Endocrine Society, 2024, DOI: 10.1210/clinem/dgae290

---name: endo-vit-d-supp-high-risk-prediabetesdescription: Suggests empiric vitamin D supplementation plus lifestyle modification to reduce diabetes progression risk in adults with high-risk prediabetes. Use when a clinician considers vitamin D for patients with prediabetes meeting 2 or more ADA glycemic criteria (fasting glucose, HbA1c, 2‑hour OGTT) to prevent diabetes.---# Vitamin D supplementation for high-risk prediabetes## STEP 1 — Gather InformationAssess glycemic status using ADA criteria: fasting plasma glucose 100‑125 mg/dL, HbA1c 5.7‑6.4%, 2‑hour plasma glucose 140‑199 mg/dL after 75‑g OGTT. Count how many of these three criteria are met. Also verify that lifestyle modification (diet, physical activity, weight loss) is being implemented or planned.## STEP 2 — Rule In / Rule Out**Rule in** high‑risk prediabetes if the patient meets **≥2** of the ADA glycemic criteria (or has documented impaired glucose tolerance). **Rule out** if 0‑1 criteria are met (low‑risk prediabetes) or glucose values are normal; empiric vitamin D supplementation is not recommended for diabetes prevention in this group.## STEP 3 — Classify or StratifyIf high‑risk prediabetes is confirmed, no further stratification by 25(OH)D level is required per guideline; the recommendation applies regardless of baseline vitamin D status. Proceed to decide on supplementation.## STEP 4 — DecideInitiate empiric vitamin D supplementation (dose not specified; trials used 842‑7543 IU daily, weighted average ≈3500 IU/day) **in addition to** continuing lifestyle modification. Re‑evaluate glycemic status periodically per usual prediabetes care.## Clinical Guardrails / Mimics / Pitfalls- Do **not** rely on serum 25(OH)D testing to guide or withhold supplementation in this population. - Avoid high‑dose intermittent bolus regimens without monitoring for hypercalcemia or nephrolithiasis. - Do **not** use in patients with established indications for vitamin D treatment (e.g., hypocalcemia, renal osteodystrophy) unless those indications are also present. - Do **not** substitute vitamin D for lifestyle modification; it is adjunctive only. - Do **not** extrapolate to pregnant individuals, children, or adults ≥75 years without separate indication.## Concrete Clinical ExampleA 58‑year‑old man with BMI 31 kg/m² has fasting glucose 112 mg/dL and HbA1c 6.0% (2 ADA criteria met); 2‑hour OGTT is 130 mg/dL. He has been advised on diet and exercise. **Decision:** Start empiric vitamin D supplementation (e.g., 2000‑3000 IU daily) and reinforce lifestyle modification.**Source:** Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline, Endocrine Society, 2024, DOI: 10.1210/clinem/dgae290

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