dromlakhani GCIH Supplemental Premeal Insulin Scale
What this skill does
Provides the supplemental (correction) short-acting insulin dose to give before each meal, on top of the scheduled bolus dose, in patients managed on the Lakhani GCIH protocol. Two scales are used depending on the patient group.
Based on Lakhani et al. 2017 (IJEM, DOI: 10.4103/ijem.IJEM_226_17).
Step 1 — Identify which scale to use
Standard scale (Lakhani / experimental protocol): Use for patients managed on the Lakhani GCIH correctional insulin protocol.
Insulin-resistant scale (Endocrine Society / control protocol): Use for patients managed on standard basal-bolus insulin without correctional insulin, or those with known insulin resistance.
Step 2 — Check premeal CBG
Measure capillary blood glucose 15 minutes before each meal.
Target premeal glucose: 100–140 mg/dl
If premeal CBG ≤ 140 mg/dl → no supplemental dose needed.
Step 3 — Apply the scale
Standard Scale (Lakhani Protocol)
| Premeal CBG (mg/dl) | Supplemental Insulin Lispro (units) |
|---|---|
| 141–180 | 4 units |
| 181–220 | 6 units |
| 221–260 | 8 units ⚠️ |
| 261–300 | 10 units |
| 301–350 | 12 units |
| 351–400 | 14 units |
| > 400 | Call endocrinologist immediately |
Insulin-Resistant Scale (Standard Basal-Bolus / Control Protocol)
| Premeal CBG (mg/dl) | Supplemental Insulin Lispro (units) |
|---|---|
| 141–180 | 6 units |
| 181–220 | 8 units |
| 221–260 | 10 units ⚠️ |
| 261–300 | 12 units |
| 301–350 | 14 units |
| 351–400 | 16 units |
| > 400 | Call endocrinologist immediately |
⚠️ At premeal CBG > 250 mg/dl: Check for diabetic ketoacidosis before giving insulin (urine ketones; if positive with pH <7.3 and HCO3 <18 → manage as DKA, do not continue this protocol).
Step 4 — Administer
- Give supplemental lispro 15 min before the meal, in addition to the scheduled premeal bolus dose.
- This is a supplemental correction — it does not replace the scheduled bolus.
- Repeat at each meal based on that premeal reading.
Clinical Guardrails
- Do not use this scale as a standalone sliding scale (i.e. without scheduled basal and bolus insulin in Group 1 patients).
- If a patient requires supplemental correction at every meal consistently → consider increasing the scheduled bolus dose rather than relying on supplemental alone.
- If CBG < 70 mg/dl before a meal → treat hypoglycemia, hold the scheduled bolus and supplemental dose, and discard remaining readings for the day.
- If CBG > 400 mg/dl → do not escalate beyond the scale; call endocrinology and check for DKA.
- Day 1 readings are not used for titration — only for immediate management.
Source: Lakhani OJ, Kumar S, Tripathi S, Desai M, Seth C. Comparison of two protocols in the management of glucocorticoid-induced hyperglycemia among hospitalized patients. Indian J Endocr Metab 2017;21:836–44. DOI: 10.4103/ijem.IJEM_226_17