How do I install the Ppgl Hypertensive Crisis Management skill?

Run npx skillmds@latest add dromlakhani/ppgl-hypertensive-crisis-management in your terminal (requires Node.js), paste this page's agent-chat prompt into Claude, Cursor, or any MCP-connected agent, or download the SKILL.md file and copy it into your agent's skills directory.

Is Ppgl Hypertensive Crisis Management safe to use?

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Which AI agents work with Ppgl Hypertensive Crisis Management?

This skill is tagged as working with Claude Code, Claude.ai, OpenAI Codex. SKILL.md is an open format, so most agents that read a skills directory can load it too.

Is Ppgl Hypertensive Crisis Management free to use?

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Who published Ppgl Hypertensive Crisis Management?

dromlakhani (@dromlakhani) published this skill. Their other Agent Skills are listed on their SkillMD profile.

Ppgl Hypertensive Crisis Management by dromlakhani

Name: Ppgl Hypertensive Crisis Management
Rating: 4.2 (5 reviews)
Author: dromlakhani

Ppgl Hypertensive Crisis Management

Executes the hypertensive crisis management algorithm for PPGL by administering intravenous phentolamine infusion followed by oral doxazosin, with addition of oral beta‑blocker for tachycardia after alpha‑blockade is established. It is triggered by clinical phrases such as 'Patient presents with hypertensive crisis suspected PPGL etiology,' 'Sudden severe hypertension with headache/palpitations,' or 'Intraoperative hypertensive surge during PPGL manipulation.'

dromlakhani Updated Sep 8, 2026 10 repo stars

File contents

Hypertensive Crisis Management Algorithm for PPGL

STEP 1 — Gather Information

Collect vital signs (BP, HR), symptoms (headache, palpitations, sweating), medication history, recent triggers (e.g., procedure, stress, tyramine‑rich foods), and confirm IV access. Action: if suspicion of PPGL hypertensive crisis is present, proceed to Step 2.

STEP 2 — Rule In / Rule Out

Rule in PPGL hypertensive crisis if any of the following are present: 'Patient presents with hypertensive crisis suspected PPGL etiology,' 'Sudden severe hypertension with headache/palpitations,' or 'Intraoperative hypertensive surge during PPGL manipulation.' If ruled in, proceed to Step 3; otherwise, manage as non‑PPGL hypertensive crisis per local protocol and end algorithm.

STEP 3 — Classify or Stratify

Classify patient into two dimensions: (1) tachycardia (HR ≥ 100 bpm) after starting IV phentolamine, and (2) acute phase resolution (SBP < 160 mmHg and DBP < 100 mmHg with symptom improvement). Action: based on classification, go to Step 4.

STEP 4 — Decide

If tachycardia is present, administer oral beta‑blocker (e.g., propranolol 10‑20 mg) after ensuring adequate alpha‑blockade; if acute phase has resolved, discontinue IV phentolamine and start oral doxazosin 2‑4 mg daily, titrating to target BP <130/80 mmHg. Continue monitoring and adjust as needed.

Clinical Guardrails / Mimics / Pitfalls

Do not administer beta‑blocker before alpha‑blockade (risk of hypertensive attack); avoid high‑dose dexamethasone; monitor for severe hypotension from phentolamine; do not use unavailable non‑selective alpha‑blockers (e.g., phenoxybenzamine); avoid abrupt cessation of phentolamine without transition to oral alpha‑blocker.

Concrete Clinical Example

A 45‑year‑old man undergoing adrenalectomy for suspected PPGL develops sudden BP 210/120 mmHg, headache, and palpitations during tumor manipulation. IV phentolamine is started at 5 mg/hr; BP falls to 150/90 mmHg within 30 min, HR rises to 110 bpm. Oral propranolol 10 mg is given, HR improves to 85 bpm. After 2 hours, BP stabilizes at 130/80 mmHg and symptoms resolve; IV phentolamine is discontinued and oral doxazosin 4 mg nightly is initiated.

Source: Japan Endocrine Society Clinical Practice Guideline for the Diagnosis and Management of Pheochromocytoma and Paraganglioma 2025, Japan Endocrine Society, 2025, DOI:10.1507/endocrj.EJ25-0165

---name: ppgl-hypertensive-crisis-managementdescription: Executes the hypertensive crisis management algorithm for PPGL by administering intravenous phentolamine infusion followed by oral doxazosin, with addition of oral beta‑blocker for tachycardia after alpha‑blockade is established. It is triggered by clinical phrases such as 'Patient presents with hypertensive crisis suspected PPGL etiology,' 'Sudden severe hypertension with headache/palpitations,' or 'Intraoperative hypertensive surge during PPGL manipulation.'---# Hypertensive Crisis Management Algorithm for PPGL## STEP 1 — Gather InformationCollect vital signs (BP, HR), symptoms (headache, palpitations, sweating), medication history, recent triggers (e.g., procedure, stress, tyramine‑rich foods), and confirm IV access. Action: if suspicion of PPGL hypertensive crisis is present, proceed to Step 2.## STEP 2 — Rule In / Rule OutRule in PPGL hypertensive crisis if any of the following are present: 'Patient presents with hypertensive crisis suspected PPGL etiology,' 'Sudden severe hypertension with headache/palpitations,' or 'Intraoperative hypertensive surge during PPGL manipulation.' If ruled in, proceed to Step 3; otherwise, manage as non‑PPGL hypertensive crisis per local protocol and end algorithm.## STEP 3 — Classify or StratifyClassify patient into two dimensions: (1) tachycardia (HR ≥ 100 bpm) after starting IV phentolamine, and (2) acute phase resolution (SBP < 160 mmHg and DBP < 100 mmHg with symptom improvement). Action: based on classification, go to Step 4.## STEP 4 — DecideIf tachycardia is present, administer oral beta‑blocker (e.g., propranolol 10‑20 mg) after ensuring adequate alpha‑blockade; if acute phase has resolved, discontinue IV phentolamine and start oral doxazosin 2‑4 mg daily, titrating to target BP <130/80 mmHg. Continue monitoring and adjust as needed.## Clinical Guardrails / Mimics / PitfallsDo not administer beta‑blocker before alpha‑blockade (risk of hypertensive attack); avoid high‑dose dexamethasone; monitor for severe hypotension from phentolamine; do not use unavailable non‑selective alpha‑blockers (e.g., phenoxybenzamine); avoid abrupt cessation of phentolamine without transition to oral alpha‑blocker.## Concrete Clinical ExampleA 45‑year‑old man undergoing adrenalectomy for suspected PPGL develops sudden BP 210/120 mmHg, headache, and palpitations during tumor manipulation. IV phentolamine is started at 5 mg/hr; BP falls to 150/90 mmHg within 30 min, HR rises to 110 bpm. Oral propranolol 10 mg is given, HR improves to 85 bpm. After 2 hours, BP stabilizes at 130/80 mmHg and symptoms resolve; IV phentolamine is discontinued and oral doxazosin 4 mg nightly is initiated.**Source:** Japan Endocrine Society Clinical Practice Guideline for the Diagnosis and Management of Pheochromocytoma and Paraganglioma 2025, Japan Endocrine Society, 2025, DOI:10.1507/endocrj.EJ25-0165

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