ADReCS Query Skill
Search ADReCS v3.3 records by any entity. Auto-detects type by prefix:
| Input Pattern | Detected As | Example |
|---|---|---|
BADD_D00142 |
BADD Drug ID | exact on drug_id column |
DB00945 |
DrugBank ID | resolved via Drug_information |
A02BC01 |
ATC code | resolved via Drug_information |
50-78-2 |
CAS RN | resolved via Drug_information |
CID2244 or bare digits |
PubChem CID | resolved via Drug_information |
D00109 (5-digit) |
KEGG ID | resolved via Drug_information |
08.06.02.001 |
ADReCS ID | substring on ADReCS_ID column |
10003781 (8-digit) |
MedDRA code | resolved via ADR_ontology |
D###### (6+ digit) |
MeSH ID | resolved via ADR_ontology |
| anything else | free text | substring on drug_name OR ADR_term |
API
| Function | Input | Returns |
|---|---|---|
load_drug_adr(path) |
txt path | DataFrame (Drug–ADR pairs) |
load_drug_info(path) |
xlsx path | DataFrame (drug metadata) |
load_adr_ontology(path) |
xlsx path | DataFrame (ADR hierarchy) |
search(entity) |
single entity string | DataFrame of matching Drug–ADR rows |
search_batch(entities) |
list of entity strings | dict[str, DataFrame] |
summarize(hits, entity) |
DataFrame + label | compact LLM-readable text |
to_json(hits) |
DataFrame | list[dict] |
Usage
See if __name__ == "__main__" block in 62_ADReCS.py for runnable examples covering: drug name lookup, BADD Drug ID, DrugBank ID, ADR term, ADReCS ID prefix, batch search, and JSON output.
Data
- Source: ADReCS v3.3 — https://www.bio-add.org/ADReCS/
- Primary file:
Drug_ADR_v3.3.txt(drug–ADR association pairs) - Drug metadata:
Drug_information_v3.3.xlsx(name, synonyms, DrugBank/KEGG/PubChem/ATC/CAS cross-refs) - ADR hierarchy:
ADR_ontology_v3.3.xlsx(ADReCS ID, ADR term, MedDRA code, MeSH ID, 4-level classification) - Path:
DATA_DIRvariable in62_ADReCS.py
Citation
Cai MC et al. (2015) ADReCS: an ontology database for aiding standardization and hierarchical classification of adverse drug reaction terms. Nucleic Acids Research 43(D1):D907–D913.