Clinicaltrials DB

Source: https://github.com/aipoch/medical-research-skills

When to Use

• You need to find clinical trials for a specific condition (e.g., “cancer”) and filter by recruitment status (e.g., Recruiting).
• You want to locate trials involving a particular intervention (drug/biologic/device) and quickly review matching studies.
• You need to retrieve full study protocol details (including eligibility criteria) for a known NCT identifier.
• You want to export or programmatically process trial metadata for downstream analysis or reporting.
• You need to validate study status and key fields (phase, locations, sponsor) from the authoritative ClinicalTrials.gov source.

Key Features

• Search studies via ClinicalTrials.gov API v2 using common filters (condition, intervention, recruitment status, result limits).
• Retrieve detailed study information by NCT ID, including protocol and eligibility criteria.
• Simple Python interface for integrating trial search and retrieval into scripts and pipelines.
• Reference documentation for advanced query parameters and field definitions (see references/api_reference.md).

Dependencies

• Python 3.9+
• requests >= 2.28

Example Usage

from scripts.query_clinicaltrials import search_studies, get_study_details

def main():
    # 1) Search studies (example: recruiting cancer studies)
    results = search_studies(
        condition="cancer",
        status="RECRUITING",
        limit=10,
    )

    print("Search results:")
    for i, item in enumerate(results, start=1):
        # The exact keys depend on the API fields returned by the implementation.
        # Print the raw item to keep this example runnable across field selections.
        print(f"\n[{i}] {item}")

    # 2) Get study details by NCT ID
    nct_id = "NCT01234567"
    study = get_study_details(nct_id)

    print(f"\n\nStudy details for {nct_id}:")
    print(study)

if __name__ == "__main__":
    main()

Implementation Details

• API Backend: Uses ClinicalTrials.gov API v2 endpoints to query study records and fetch study details.
• Search Parameters:
  • condition: Condition/disease term used to match relevant studies.
  • status: Recruitment status filter (e.g., RECRUITING).
  • limit: Maximum number of records to return.
• Study Detail Retrieval:
  • get_study_details(nct_id) fetches the full record for a single study identified by its NCT ID and returns the protocol-level information (including eligibility criteria when available).
• Advanced Queries / Field Definitions:
  • For additional query parameters, response fields, and definitions, refer to references/api_reference.md.