hvkshetry Medical Records
Tool Mapping (health-graph-mcp)
| Task | Tool |
|---|---|
| Create/list subject | upsert_subject, list_subjects, link_subject_identifier |
| Ingest genome raw data | ingest_genome_artifact |
| Query variant/genotype calls | query_genotype_calls |
| Load PharmCAT outputs | run_pgx_pipeline |
| Get PGx profile | get_pgx_profile, list_pgx_recommendations |
| Ingest curated assertions | ingest_clinical_assertions, query_variant_assertions |
| Ingest/query associations | ingest_trait_associations, get_polygenic_context |
| Ingest labs/admin FHIR data | ingest_fhir_bundle, query_labs, get_lab_trends |
| Coverage codification/check | ingest_coverage_artifacts, evaluate_coverage, explain_coverage_determination |
| Paperless document sync/linkage | sync_paperless_medical_metadata, get_document_linkage |
| Literature evidence graph | add_literature_evidence, query_evidence_graph |
| Policy-gated recommendation view | get_wellness_recommendations |
| Source freshness and refresh | health_graph_status, refresh_source |
Drug Reference (medical-mcp)
| Task | Tool |
|---|---|
| Search FDA drug database | medical.search_drugs |
| Drug details by NDC code | medical.get_drug_details |
| Clinical practice guidelines | medical.get_clinical_guidelines |
| PubMed literature search | medical.search_medical_literature |
| Pediatric drug info | medical.search_pediatric_drugs |
Use drug reference tools when:
- PGx profile recommends dosage adjustment — look up standard dosing via
medical.search_drugs - Clinical assertion references a guideline — pull the guideline via
medical.get_clinical_guidelines - Subject asks about a medication — search PubMed for recent evidence
Evidence Policy
- Tier 1 (
actionable_with_guardrails): guideline-backed PGx. - Tier 2 (
review_required): clinically curated assertions. - Tier 3 (
context_only): GWAS/PGS context. - Tier 4 (
research_only): exploratory evidence only.
Nutrigenomics and exercise genomics remain research_only.
Source-of-Truth Policy
health-graphis authoritative for genome/clinical context, recommendation availability, and evidence tiers.paperlessis a document-source/provenance bridge only; use linked metadata (paperless_doc_id) for traceability.- Do not treat Paperless search results (or lack of results) as a signal that genomic/clinical data is absent.
Reporting Quality Rules
- For weekly/persona communications, do not stop at tier counts.
- Explain each Tier 1-Tier 4 finding in plain language with:
- recommendation target (gene-drug or variant-trait),
- why it applies to the subject (genotype/phenotype metadata),
- when it matters (decision trigger),
- and tier-appropriate next-step framing.
- Every genome-informed explanation must answer "so what?" for the subject:
- Start with the plain-English takeaway, not the genotype label
- Say whether anything needs to happen now; if not, say that explicitly
- Say what future decision this could affect, if any
- Translate technical terms immediately; do not leave star alleles, rsids, or metabolizer labels unexplained
- For Tier 3 and Tier 4 items, state clearly that they are watchlist or research context and should not drive treatment or behavior changes on their own
- Tier framing in reports:
- Tier 1: actionable with guardrails.
- Tier 2: review required before action.
- Tier 3: context-only, non-deterministic.
- Tier 4: research-only hypothesis.
- De-duplicate overlapping recommendations by gene+drug so reports are concise and non-redundant.
Document Bridge
- Keep Paperless as OCR/document source of record.
- Persist only linked metadata and assertions in health graph.
- Use
paperless_doc_idfor provenance across records.