Colorectal Pathology Specialist
Complete colorectal cancer pathology workflow toolkit combining compliance checking, staging, MSI/MMR reporting, and coding.
When to Use This Skill
Use this skill for:
- Colorectal cancer pathology report validation
- Colon and rectal carcinoma specimens (colectomy, polypectomy, TEM)
- CAP/ICCR compliance checking with severity scoring
- TNM staging calculation (AJCC 8th edition)
- MSI/MMR testing interpretation
- Mesorectal excision quality grading (rectal specimens)
- Tumor board summary generation
- SNOMED CT coding assistance
Supported Specimen Types
- Right hemicolectomy (cecum, ascending colon)
- Left hemicolectomy (descending colon)
- Sigmoid colectomy
- Low anterior resection (rectal)
- Abdominoperineal resection (rectal)
- Total mesorectal excision (TME)
- Polypectomy specimens
- Transanal excision (TEM/TAMIS)
Key Features
- Compliance Checking: Validates against CAP ColoRectal and ICCR Colorectal Cancer protocols
- TNM Staging: AJCC 8th edition colorectal staging with pT/pN/M calculation
- MSI/MMR Reporting: Microsatellite instability and mismatch repair interpretation
- Mesorectal Quality: TME quality grading (complete/nearly complete/incomplete)
- Template Generation: Colon and rectal specimen synoptic templates
- Tumor Board Summaries: Concise 3-5 line MDT presentation format
- SNOMED Coding: Colorectal-specific code suggestions
Reference Files
When processing reports, reference these files on-demand (DO NOT load at startup):
- Diagnosis guidelines:
references/diagnosis/colorectal_resection.md
- Macroscopy guidelines:
references/macroscopy/colorectal_macroscopy.md
- TNM staging:
../../shared-references/staging/tnm_stage_calculator.md
- Synoptic templates:
../../shared-references/templates/synoptic_templates.md
- SNOMED codes:
../../shared-references/coding/snomed_ct_codes.md
Usage Examples
# Validate report compliance
claude "Check this colorectal report using colorectal-pathology-specialist" < report.txt
# Generate staging
claude "What stage is pT3 N1b M0 for colorectal using colorectal-pathology-specialist"
# Create template
claude "Generate rectal TME template using colorectal-pathology-specialist"
# MSI interpretation
claude "Interpret MLH1 loss, PMS2 loss, MSH2 intact, MSH6 intact using colorectal-pathology-specialist"
Processing Instructions
When analyzing colorectal pathology reports:
- Identify request type (compliance check, staging, template, MSI interpretation, summary, coding)
- Read relevant reference file on-demand based on request
- Process the report using appropriate guidelines
- Generate output in requested format
- DO NOT load all reference files upfront
Compliance Scoring
Use severity-based weighting:
- Critical elements (tumor size, grade, margins, CRM, nodes, MSI): -15 points each
- Major elements (LVI, PNI, tumor deposits, perforation): -5 points each
- Minor elements (tumor location, distance from margins): -2 points each
Scoring: 90-100 (Compliant) | 70-89 (Minor issues) | 50-69 (Major issues) | <50 (Critical)
Cross-Validation Checks
Always validate:
- pT category vs tumor invasion depth
- pN category vs positive node count
- Stage group vs pT/pN/M combination
- CRM status (rectal) vs margin measurements
- MSI status vs MMR immunohistochemistry pattern
Language Support
Supports English and Turkish - detect from user prompt and use appropriate template file.
Note: This is a minimal skill definition. Large reference files are loaded on-demand only when processing requests, not at skill startup.
1---2name: colorectal-pathology-specialist3description: Comprehensive colorectal cancer pathology workflow combining CAP/ICCR compliance validation, synoptic template generation, TNM staging (AJCC 8th edition), MSI/MMR testing interpretation, mesorectal excision quality (MERCURY) grading, tumor board summaries, and SNOMED coding. Use when the user uploads or pastes a colorectal pathology report (colectomy, low anterior resection, abdominoperineal resection, polypectomy) and asks to "check colorectal report", "validate CAP ColoRectal protocol", "stage this colorectal cancer", "interpret MSI/MMR", "assess TME quality", or any colorectal-cancer-specific pathology task. Supports .pdf, .docx, .txt input in English and Turkish.4license: MIT5---67# Colorectal Pathology Specialist89Complete colorectal cancer pathology workflow toolkit combining compliance checking, staging, MSI/MMR reporting, and coding.1011## When to Use This Skill1213Use this skill for:14- Colorectal cancer pathology report validation15- Colon and rectal carcinoma specimens (colectomy, polypectomy, TEM)16- CAP/ICCR compliance checking with severity scoring17- TNM staging calculation (AJCC 8th edition)18- MSI/MMR testing interpretation19- Mesorectal excision quality grading (rectal specimens)20- Tumor board summary generation21- SNOMED CT coding assistance2223## Supported Specimen Types2425- Right hemicolectomy (cecum, ascending colon)26- Left hemicolectomy (descending colon)27- Sigmoid colectomy28- Low anterior resection (rectal)29- Abdominoperineal resection (rectal)30- Total mesorectal excision (TME)31- Polypectomy specimens32- Transanal excision (TEM/TAMIS)3334## Key Features35361. **Compliance Checking**: Validates against CAP ColoRectal and ICCR Colorectal Cancer protocols372. **TNM Staging**: AJCC 8th edition colorectal staging with pT/pN/M calculation383. **MSI/MMR Reporting**: Microsatellite instability and mismatch repair interpretation394. **Mesorectal Quality**: TME quality grading (complete/nearly complete/incomplete)405. **Template Generation**: Colon and rectal specimen synoptic templates416. **Tumor Board Summaries**: Concise 3-5 line MDT presentation format427. **SNOMED Coding**: Colorectal-specific code suggestions4344## Reference Files4546When processing reports, reference these files on-demand (DO NOT load at startup):4748- **Diagnosis guidelines**: `references/diagnosis/colorectal_resection.md`49- **Macroscopy guidelines**: `references/macroscopy/colorectal_macroscopy.md`50- **TNM staging**: `../../shared-references/staging/tnm_stage_calculator.md`51- **Synoptic templates**: `../../shared-references/templates/synoptic_templates.md`52- **SNOMED codes**: `../../shared-references/coding/snomed_ct_codes.md`5354## Usage Examples5556```bash57# Validate report compliance58claude "Check this colorectal report using colorectal-pathology-specialist" < report.txt5960# Generate staging61claude "What stage is pT3 N1b M0 for colorectal using colorectal-pathology-specialist"6263# Create template64claude "Generate rectal TME template using colorectal-pathology-specialist"6566# MSI interpretation67claude "Interpret MLH1 loss, PMS2 loss, MSH2 intact, MSH6 intact using colorectal-pathology-specialist"68```6970## Processing Instructions7172When analyzing colorectal pathology reports:73741. **Identify request type** (compliance check, staging, template, MSI interpretation, summary, coding)752. **Read relevant reference file** on-demand based on request763. **Process the report** using appropriate guidelines774. **Generate output** in requested format785. **DO NOT load all reference files** upfront7980## Compliance Scoring8182Use severity-based weighting:83- Critical elements (tumor size, grade, margins, CRM, nodes, MSI): -15 points each84- Major elements (LVI, PNI, tumor deposits, perforation): -5 points each85- Minor elements (tumor location, distance from margins): -2 points each8687Scoring: 90-100 (Compliant) | 70-89 (Minor issues) | 50-69 (Major issues) | <50 (Critical)8889## Cross-Validation Checks9091Always validate:92- pT category vs tumor invasion depth93- pN category vs positive node count94- Stage group vs pT/pN/M combination95- CRM status (rectal) vs margin measurements96- MSI status vs MMR immunohistochemistry pattern9798## Language Support99100Supports English and Turkish - detect from user prompt and use appropriate template file.101102---103104**Note**: This is a minimal skill definition. Large reference files are loaded on-demand only when processing requests, not at skill startup.
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