bg-szy
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- ▌ Job Application Optimizer · bg-szyOptimize job applications by tailoring resumes to job postings, generating customized cover letters, and preparing role-specific interview questions. Analyzes job descriptions to highlight relevant skills and experience. Use when users need to apply for jobs, customize resumes, or prepare for interviews.
- ▌ Lookalike Customer Finder · bg-szyInput your best customers and find 100+ companies that match the profile. Uses firmographic data, tech stack, growth signals, and similarity scoring to identify ideal prospects. Use when building target account lists or expanding to new markets.
- ▌ Pricing Change Strategist · bg-szyDesign and roll out a price increase or packaging change without triggering churn. Segments the base by price sensitivity, models revenue and churn scenarios, decides grandfathering and notice strategy, and produces the full comms kit (customer email, in-app notice, sales talk track, support FAQ, objection handling). Use when raising prices, repackaging tiers, or moving customers to new plans.
- ▌ React Component Generator · bg-szyGenerate React components with TypeScript, proper props, hooks, and accessibility. Use when creating new React components, UI elements, or refactoring existing components.
- ▌ Responsive Layout Builder · bg-szyBuild responsive layouts with CSS Grid, Flexbox, and container queries. Use when creating responsive designs, fixing layout issues, or building mobile-first layouts.
- ▌ Vercel Composition Patterns · bg-szyReact composition patterns that scale. Use when refactoring components with boolean prop proliferation, building flexible component libraries, or designing reusable APIs. Triggers on tasks involving compound components, render props, context providers, or component architecture. Includes React 19 API changes.
- ▌ Vercel React Best Practices · bg-szyReact and Next.js performance optimization guidelines from Vercel Engineering. This skill should be used when writing, reviewing, or refactoring React/Next.js code to ensure optimal performance patterns. Triggers on tasks involving React components, Next.js pages, data fetching, bundle optimization, or performance improvements.
- ▌ Academic Paper Strategist · bg-szySystematic strategic planning framework for philosophy and interdisciplinary academic papers targeting preprint platforms (PhilArchive, arXiv, PhilSci-Archive). Use when users want to: (1) plan a paper on a specific topic, (2) identify research gaps and assess originality, (3) develop optimized paper outlines, (4) prepare for preprint submission, or (5) understand platform requirements and writing standards. Triggered by phrases like 'plan a paper on,' 'help me design a paper about,' 'identify research gaps in,' 'is this idea original,' or when users need structured research planning. The skill guides through three phases: Platform Analysis (identifying target venue and studying sample papers), Theoretical Framework (AI-driven literature search and gap identification), and Outline Optimization (structured design with reviewer-perspective self-assessment). Each phase includes quality evaluation standards and validation checkpoints.
- ▌ Alphafold Database Access · bg-szyAccess AlphaFold DB's 200M+ predicted structures by UniProt ID. Download PDB/mmCIF, analyze pLDDT/PAE, bulk-fetch proteomes via Google Cloud. For experimental structures use PDB; for prediction use ColabFold or ESMFold.
- ▌ Armored Cart Design Agent · bg-szyAI-powered design of armored CAR-T cells with cytokine/chemokine expression for enhanced solid tumor efficacy, including IL-12, IL-15, IL-18, and IL-7 armoring strategies.
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- ▌ Bioinformatics Singlecell · bg-szyAdvanced single-cell multi-omics analysis including scRNA-seq, scCITE-seq, scATAC-seq, and TARGET-seq. Use when analyzing single-cell data, cell type identification, trajectory analysis, differential expression, UMAP/clustering, integrating protein and RNA modalities (TotalVI), or working with Scanpy, Seurat, scvi-tools. Includes workflows for MPN, hematologic malignancies, megakaryocyte biology.
- ▌ Cellular Senescence Agent · bg-szyAI-powered analysis of cellular senescence for aging research, cancer therapy response, and senolytic drug development.
- ▌ Data Visualization Expert · bg-szyGenerate insightful, publication-quality visualizations from complex datasets.
- ▌ Exosome Ev Analysis Agent · bg-szyAI-powered extracellular vesicle and exosome analysis for cancer biomarker discovery, liquid biopsy applications, and intercellular communication profiling.
- ▌ Exploratory Data Analysis · bg-szyMethodology for exploratory data analysis on scientific files. Decision frameworks by data type (tabular, sequence, image, spectral, structural, omics), quality assessment, report generation, format detection across 200+ formats. Use when given a data file for initial exploration or to pick an analysis before a pipeline.
- ▌ Inventory Demand Planning · bg-szyCodified expertise for demand forecasting, safety stock optimization, replenishment planning, and promotional lift estimation at multi-location retailers. Informed by demand planners with 15+ years experience managing hundreds of SKUs. Includes forecasting method selection, ABC/XYZ analysis, seasonal transition management, and vendor negotiation frameworks. Use when forecasting demand, setting safety stock, planning replenishment, managing promotions, or optimizing inventory levels.
- ▌ Literature Search Biorxiv · bg-szyBrowse, filter, and download life sciences, biology, and medical preprints from bioRxiv and medRxiv. Supports fetching paper metadata by DOI, and browsing by date range with category and keyword filters. Keyword filtering is local, so date ranges MUST be narrow (1-4 weeks) with a category to prevent timeouts.
- ▌ Nicheformer Spatial Agent · bg-szyFoundation model-powered spatial transcriptomics analysis leveraging 53M+ spatially resolved cells for cellular architecture modeling and tissue niche discovery.
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- ▌ Returns Reverse Logistics · bg-szyCodified expertise for returns authorization, receipt and inspection, disposition decisions, refund processing, fraud detection, and warranty claims management. Informed by returns operations managers with 15+ years experience. Includes grading frameworks, disposition economics, fraud pattern recognition, and vendor recovery processes. Use when handling product returns, reverse logistics, refund decisions, return fraud detection, or warranty claims.
- ▌ Shap Model Explainability · bg-szyModel interpretability via SHAP (Shapley values from game theory). Covers explainer choice (Tree, Deep, Linear, Kernel, Gradient, Permutation), feature attribution, and plots (waterfall, beeswarm, bar, scatter, force, heatmap). Use to explain ML predictions, rank features, debug models, audit fairness, or compare models. Works with tree, deep, linear, and black-box models.
- ▌ Spatial Epigenomics Agent · bg-szyAI-powered spatial epigenomics analysis combining chromatin accessibility, histone modifications, and DNA methylation with spatial coordinates for tissue architecture mapping.
- ▌ Tcr Pmhc Prediction Agent · bg-szyAI-powered TCR-peptide-MHC interaction prediction using AlphaFold3 and deep learning for therapeutic TCR discovery, neoantigen validation, and T cell immunogenicity assessment.
- ▌ Tpd Ternary Complex Agent · bg-szyAI-powered ternary complex prediction for targeted protein degradation, modeling POI-degrader-E3 ligase assemblies to optimize PROTAC and molecular glue efficacy.
- ▌ Tumor Heterogeneity Agent · bg-szyAI-powered intratumor heterogeneity analysis for clonal architecture reconstruction, subclonal evolution tracking, and therapy resistance prediction using multi-region and longitudinal sequencing.
- ▌ Python Error Handling · bg-szyPython error handling patterns including input validation, exception hierarchies, and partial failure handling. Use when implementing validation logic, designing exception strategies, handling batch processing failures, or building robust APIs.
- ▌ Python Infrastructure · bg-szyPython patterns for system reliability — background jobs and task queues (Celery, async), resilience and recovery (retries, backoff, timeouts, circuit breakers via tenacity), and observability (structured logging via structlog, metrics, distributed tracing, golden signals). USE WHEN building async workers, queueing tasks, handling transient network/IO failures, instrumenting Python services for production, designing retry policies, configuring logging or tracing, or any combination of these system-reliability concerns. NOT FOR language idioms or type hygiene (use `writing-python`) or project setup and dependency management (use `uv`).
- ▌ Customer Review Aggregator · bg-szyAggregate and analyze customer reviews from G2, Capterra, Trustpilot, App Store, and other platforms. Performs sentiment analysis, identifies pain points, extracts feature feedback, generates marketing claims, and compares competitor reviews. Use when users need review analysis, competitive intelligence, or customer feedback insights.
- ▌ Job Profitability Analyzer · bg-szyFind out which clients and jobs actually make money -- allocate real costs (labor hours, materials, subs, overhead) against what each job billed, and rank every client by true margin. Most service businesses discover their biggest client is their least profitable.
- ▌ Webinar Content Repurposer · bg-szyTransform webinar recordings into multiple content assets including blog post series, social media snippets, infographic ideas, email sequences, and sales one-pagers. Extracts key moments, quotes, and insights for maximum content ROI. Use when users need to repurpose webinars, video content, or live presentations into multi-channel marketing materials.
- ▌ Cookie Policy Page Generator · bg-szyWhen the user wants to create or optimize a cookie policy page. Also use when the user mentions "cookie policy," "cookies," "cookie consent," "GDPR cookies," "cookie banner," "cookie notice," "tracking cookies," or "cookie settings." For legal overview, use legal-page-generator.
- ▌ Bio Workflows Cnv Pipeline · bg-szy bundleEnd-to-end copy number variant detection workflow from BAM files. Covers CNVkit analysis for exome/targeted sequencing with visualization and annotation. Use when detecting copy number alterations from sequencing data.
- ▌ Bio Workflows Hic Pipeline · bg-szy bundleEnd-to-end Hi-C analysis workflow from contact pairs to compartments, TADs, and loops. Covers cooler matrices, cooltools analysis, and visualization. Use when processing Hi-C data to compartments and TADs.
- ▌ Bio Workflows Imc Pipeline · bg-szy bundleEnd-to-end imaging mass cytometry workflow from raw acquisitions to spatial cell analysis. Orchestrates image preprocessing, segmentation, phenotyping, and spatial statistics. Use when analyzing imaging mass cytometry data end-to-end.
- ▌ Bio Workflows Rnaseq To De · bg-szy bundleEnd-to-end RNA-seq workflow from FASTQ files to differential expression results. Covers QC, quantification (Salmon or STAR+featureCounts), and DESeq2 analysis with visualization. Use when running RNA-seq from FASTQ to DE results.
- ▌ Bio Workflows Tcr Pipeline · bg-szy bundleEnd-to-end TCR/BCR repertoire analysis from FASTQ to clonotype diversity metrics. Use when analyzing immune repertoire sequencing data from bulk or single-cell experiments.
- ▌ Bioservices Multi Database · bg-szyUnified Python interface to 40+ bioinformatics web services: UniProt proteins, KEGG pathways, ChEMBL/ChEBI/PubChem, BLAST, cross-database ID mapping, GO annotations, PPI. For deep single-DB queries use dedicated tools (gget for Ensembl, pubchempy for PubChem); bioservices excels at cross-database workflows.
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- ▌ Context Driven Development · bg-szyCreates and maintains project context artifacts (product.md, tech-stack.md, workflow.md, tracks.md) in a `conductor/` directory. Scaffolds new projects from scratch, extracts context from existing codebases, validates artifact consistency before implementation, and synchronizes documents as the project evolves. Use when setting up a project, creating or updating product docs, managing a tech stack file, defining development workflows, tracking work units, onboarding to an existing codebase, or running project scaffolding.
- ▌ Crispr Offtarget Predictor · bg-szy bundlePredicts potential off-target sites for a given sgRNA sequence using mismatch analysis.
- ▌ Foldseek Structural Search · bg-szyPerforms 3D structural searches of proteins against various databases (PDB, AlphaFold, CATH, MGnify, etc.) using the Foldseek API. Use ONLY when the user provides a physical 3D coordinate file (.cif, .mmcif, or .pdb) and wants to find structurally similar proteins. Do NOT use if the user only provides a protein sequence, gene name, or UniProt ID.
- ▌ Literature Search Openalex · bg-szyQuery the OpenAlex scholarly database for research papers, authors, institutions, topics, sources, publishers, funders, geo-locations, and keywords. Use when searching academic papers, resolving DOIs, downloading open-access PDFs, finding an author's publications, aggregating bibliometric data (citation counts, h-index, impact factor), exploring the research taxonomies, or performing DOI lookups.
- ▌ Long Read Sequencing Agent · bg-szyAI-powered analysis of long-read sequencing data (PacBio, ONT) for structural variant detection, isoform discovery, epigenetic modifications, and de novo assembly.
- ▌ Multimodal Medical Imaging · bg-szy bundleAnalyzes medical images (X-ray, MRI, CT) using multimodal LLMs to identify anomalies and generate reports.
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- ▌ Time Resolved Cryoem Agent · bg-szyAI-powered time-resolved cryo-EM analysis for capturing protein dynamics, drug-binding kinetics, and conformational transitions for dynamics-based drug discovery.
- ▌ Tme Immune Profiling Agent · bg-szyComprehensive AI-powered tumor microenvironment immune profiling integrating bulk deconvolution, single-cell analysis, and spatial transcriptomics for immunotherapy biomarker discovery.
- ▌ Ucsc Conservation And Tfbs · bg-szyFetch Evolutionary Conservation scores (phyloP, phastCons) and Transcription Factor Binding Sites (TFBS) from the UCSC Genome Browser. Use when analyzing whether genomic variants or regions are evolutionarily conserved, functionally important, or bounded by TF regulators across major projects (ENCODE, JASPAR, ReMap).
- ▌ Python Design Patterns · bg-szyPython design patterns including KISS, Separation of Concerns, Single Responsibility, and composition over inheritance. Use when making architecture decisions, refactoring code structure, or evaluating when abstractions are appropriate.
- ▌ Writing Dna Discovery · bg-szyCapture a writer's voice DNA through collaborative interview and sample analysis. Use when someone wants to document their writing voice for use with a ghost writer skill. Produces a Voice DNA Document with patterns, anti-patterns, and actionable guidance. Handles one register/mode per session, supports refinement over time.
- ▌ Cowork Medical Bill Auditor · bg-szyPoint Cowork at a folder of medical bills and insurance EOBs -- matches every bill to its explanation of benefits, catches duplicate charges, balance-billing, and bills that ignore your insurance, then drafts the dispute letters and phone scripts. Most medical bills contain errors; this finds them.
- ▌ Meeting Intelligence System · bg-szyAnalyze meeting transcripts to extract decisions, action items, blockers, sentiment, and generate follow-up emails. Use when user provides meeting notes, transcripts, or recordings and needs structured summaries or action tracking.
- ▌ Vercel React View Transitions · bg-szyGuide for implementing smooth, native-feeling animations using React's View Transition API (`<ViewTransition>` component, `addTransitionType`, and CSS view transition pseudo-elements). Use this skill whenever the user wants to add page transitions, animate route changes, create shared element animations, animate enter/exit of components, animate list reorder, implement directional (forward/back) navigation animations, or integrate view transitions in Next.js. Also use when the user mentions view transitions, `startViewTransition`, `ViewTransition`, transition types, or asks about animating between UI states in React without third-party animation libraries.
- ▌ Bio Clip Seq Clip Alignment · bg-szy bundleAlign CLIP-seq reads to the genome with crosslink site awareness. Use when mapping preprocessed CLIP reads for peak calling.
- ▌ Bio Phylo Tree Manipulation · bg-szy bundleModify phylogenetic tree structure using Biopython Bio.Phylo. Use when rooting trees with outgroups or midpoint, pruning taxa, collapsing clades, ladderizing branches, or extracting subtrees.
- ▌ Bio Reporting Figure Export · bg-szy bundleExports publication-ready figures in various formats with proper resolution, sizing, and typography. Use when preparing figures for journal submission, creating vector graphics for presentations, or ensuring consistent figure styling across analyses.
- ▌ Bio Workflows Clip Pipeline · bg-szy bundleEnd-to-end CLIP-seq analysis from FASTQ to binding sites and motif enrichment. Use when analyzing protein-RNA interactions from CLIP-based methods.
- ▌ Bio Workflows Gwas Pipeline · bg-szy bundleEnd-to-end GWAS workflow from VCF to association results. Covers PLINK QC, population structure correction, and association testing for case-control or quantitative traits. Use when running genome-wide association studies.
- ▌ Cart Design Optimizer Agent · bg-szyAI-guided CAR-T cell design for solid tumors using antigen prioritization, safety-by-design architectures, and exhaustion-resistant engineering.
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- ▌ Clinical Note Summarization · bg-szy bundleStructure raw clinical notes into SOAP-format summaries with explicit contradictions, missing data, and ICD-linked assessments using the provided prompt + usage script.
- ▌ Cryoem AI Drug Design Agent · bg-szyAI-powered integration of cryo-EM structural data with generative AI and molecular dynamics for structure-based drug design targeting flexible proteins and membrane complexes.
- ▌ Digital Twin Clinical Agent · bg-szyAI-powered patient digital twin creation for clinical trial simulation, treatment outcome prediction, and personalized medicine using real-world data and multi-omics integration.
- ▌ Epigenomics Methylgpt Agent · bg-szyAI-powered DNA methylation analysis using MethylGPT foundation models for epigenomic profiling, differential methylation detection, and cancer epigenome characterization.
- ▌ Literature Search Europepmc · bg-szySearch Europe PMC for scientific literature and download open-access full texts and PDFs. Retrieve full-text XML/plain text by PMCID, get citation lists and bibliography.
- ▌ Pan Cancer Multiomics Agent · bg-szyAI-powered pan-cancer analysis integrating genomic, transcriptomic, proteomic, and epigenomic data for cancer subtyping, driver identification, and cross-cancer pattern discovery.
- ▌ Prompt Engineering Patterns · bg-szyThis skill should be used when the user asks to "optimize a prompt", "improve prompt performance", "design a prompt template", "write better prompts", "debug prompt issues", "use chain-of-thought", "structured prompting", "few-shot prompting", or wants to apply advanced prompt engineering patterns for production LLM applications.
- ▌ Prs Net Deep Learning Agent · bg-szyGeometric deep learning-based polygenic risk score prediction using PRS-Net for modeling gene interactions, enhanced disease prediction, and cross-ancestry portability.
- ▌ Variant Interpretation Acmg · bg-szy bundleClassifies genetic variants according to ACMG (American College of Medical Genetics) guidelines.
- ▌ Linkedin Sales Navigator Alt · bg-szyBuild targeted prospect lists by analyzing LinkedIn profiles, extracting job titles, companies, locations, and recent activity. Identifies decision-makers, tracks job changes for warm outreach, and enriches contact data. Use when users need to find prospects, build lead lists, or track decision-maker movements.
- ▌ Generative Engine Optimization · bg-szyWhen the user wants to optimize for AI search visibility (ChatGPT, Claude, Perplexity, AI Overviews). Also use when the user mentions "GEO," "AEO," "generative engine optimization," "AI search visibility," "LLM optimization," "GitHub GEO," "Grokipedia," "optimize for ChatGPT," "AI Overviews," "Bing Copilot," "Yandex AI," "Perplexity optimization," "GEO strategy," or "AI search optimization." For third-party publishing strategy (which platforms to use), use parasite-seo. For GitHub repos, README, and Awesome lists, use github. For Medium.com only, use medium-posts. For Grokipedia edits, use grokipedia-recommendations. For traditional Google SERP strategy, use seo-strategy.
- ▌ Bio Phylo Tree Visualization · bg-szy bundleDraw and export phylogenetic trees using Biopython Bio.Phylo with matplotlib. Use when creating publication-quality tree figures, customizing colors and labels, or exporting to image formats.
- ▌ Bio Reporting Quarto Reports · bg-szy bundleBuild reproducible scientific documents, presentations, and websites with Quarto supporting R, Python, Julia, and Observable JS. Use when creating reproducible reports with Quarto.
- ▌ Bio Workflows Merip Pipeline · bg-szy bundleEnd-to-end MeRIP-seq analysis from FASTQ to m6A peaks and differential methylation. Use when analyzing epitranscriptomic m6A modifications from immunoprecipitation data.
- ▌ Bio Workflows Smrna Pipeline · bg-szy bundleEnd-to-end small RNA-seq analysis from FASTQ to differential miRNA expression. Use when analyzing miRNA, piRNA, or other small RNA sequencing data.
- ▌ Coagulation Thrombosis Agent · bg-szyAI-powered analysis of coagulation disorders, thrombosis risk prediction, anticoagulation management, and platelet function assessment using machine learning.
- ▌ Deep Visual Proteomics Agent · bg-szyAI-driven integration of cellular imaging, laser microdissection, and ultra-sensitive mass spectrometry for spatially-resolved single-cell proteomics.
- ▌ Human Protein Atlas Database · bg-szyUse when you want to retrieve semi-quantitative protein expression and spatial localisation data from the Human Protein Atlas (HPA).
- ▌ Organoid Drug Response Agent · bg-szyAI-powered analysis of patient-derived organoid (PDO) drug screening for personalized oncology treatment selection and biomarker discovery.
- ▌ Protein Structure Prediction · bg-szy bundlePredicts 3D protein structures from amino acid sequences using ESMFold or AlphaFold3 (mock).
- ▌ Tumor Clonal Evolution Agent · bg-szyAI-powered analysis of tumor clonal architecture, subclonal dynamics, and evolutionary trajectories from multi-region sequencing and longitudinal liquid biopsy data.
- ▌ Azure Network Calculator · bg-szy bundleAzure network planning — CIDR calculation, subnet allocation, VNet sizing, IP address planning, snet layout, network capacity, Azure networking, hub-spoke topology. USE WHEN CIDR, subnet, VNet, snet, network planning, IP address, Azure networking, calculate network, plan network, validate CIDR, network capacity, address space.
- ▌ Cold Email Sequence Generator · bg-szyGenerate personalized cold email sequences (7-14 emails) with A/B test subject lines, follow-up timing recommendations, and integrated social proof. Creates multi-touch campaigns optimized for response rates. Use when users need outbound email campaigns, sales sequences, or lead generation emails.
- ▌ Cowork Contract Renewal Radar · bg-szySweep a contracts folder and extract every renewal date, auto-renew clause, notice window, and price-escalation term into a renewal calendar -- then create calendar reminders ahead of each notice deadline via Cowork's calendar write tools. The skill that stops auto-renewals from ambushing you.
- ▌ Executive Dashboard Generator · bg-szyTransform raw data from CSVs, Google Sheets, or databases into executive-ready reports with visualizations, key metrics, trend analysis, and actionable recommendations. Creates data-driven narratives for leadership. Use when users need to turn spreadsheets into executive summaries or board reports.
- ▌ Hyperframes Explainer Builder · bg-szyTurn a website URL, product docs, or a founder's rambling description into a tight 60-90 second explainer video built in HyperFrames -- problem/solution narrative, animated product walkthrough scenes, captions, and voiceover, ready for the homepage hero, sales emails, and onboarding.
- ▌ Multi Agent Client Onboarding · bg-szyUses Agent SDK to deploy 3 parallel agents for client onboarding -- workflow auditor, tech stack mapper, and strategy drafter. Real consulting workflow that produces a complete client assessment.
- ▌ Sales Methodology Implementer · bg-szyImplement proven sales methodologies (MEDDIC, BANT, Sandler, Challenger, SPIN) across your team. Generate framework-specific questions, score deals, train reps, and enforce consistent qualification. Use when implementing or optimizing sales processes.
- ▌ Zhuangxiu Shuidian Bikeng Ready · bg-szy bundle【装修隐蔽工程必看】水电是装修第一步、最容易被坑的环节——绕路加米数、不估价坐地起价、进口水管忽悠、水电包死偷工、走顶多花钱、横平竖直当质量、验收一堆专业名词看不懂？这个Skill内置装修课堂知识库，覆盖水电规划、计费估价、施工交底、验收标准、常见坑与套路、10种不建议做法、插座开关布局、防水避坑、水路改造、电路强弱电。适合拿到水电报价、准备交底、担心被加价、想自己看懂水电的业主。
- ▌ Bio Reporting Jupyter Reports · bg-szy bundleCreates reproducible Jupyter notebooks for bioinformatics analysis with parameterization using papermill. Use when generating automated analysis reports, running notebook-based pipelines, or creating shareable computational notebooks.
- ▌ Bio Transcription Translation · bg-szy bundleTranscribe DNA to RNA and translate to protein using Biopython. Use when converting between DNA, RNA, and protein sequences, finding ORFs, or using alternative codon tables.
- ▌ Chromosomal Instability Agent · bg-szyAI-powered analysis of chromosomal instability (CIN) signatures for cancer prognosis, immunotherapy response prediction, and therapeutic vulnerability identification.
- ▌ Computational Pathology Agent · bg-szy bundleAnalyze Whole Slide Images (WSI) for digital pathology, including tissue segmentation and feature extraction.
- ▌ Cytokine Storm Analysis Agent · bg-szyAI-powered cytokine release syndrome (CRS) and cytokine storm analysis for prediction, monitoring, and management in immunotherapy and infectious disease.
- ▌ Data Visualization Biomedical · bg-szyPublication-quality visualizations for biomedical and genomics data. Use when creating volcano plots, heatmaps, UMAP plots, dot plots, survival curves, forest plots, or multi-panel figures. Includes scanpy, matplotlib, seaborn, plotly workflows with journal-ready aesthetics and proper statistical annotations.
- ▌ Liquid Biopsy Analytics Agent · bg-szyComprehensive analysis of liquid biopsy data (ctDNA, CTCs) for cancer detection, MRD monitoring, and response tracking.
- ▌ Mpn Progression Monitor Agent · bg-szyAI-powered myeloproliferative neoplasm monitoring for disease progression prediction, treatment response tracking, and transformation risk assessment in PV, ET, and myelofibrosis.
- ▌ Tcr Repertoire Analysis Agent · bg-szyAI-powered T-cell receptor repertoire analysis for cancer diagnosis, immunotherapy response prediction, and therapeutic TCR selection using deep learning and multi-layer ML approaches.
- ▌ Tooluniverse Variant Analysis · bg-szy bundleProduction-ready VCF processing, variant annotation, mutation analysis, and structural variant (SV/CNV) interpretation for bioinformatics questions. Parses VCF files (streaming, large files), classifies mutation types (missense, nonsense, synonymous, frameshift, splice, intronic, intergenic) and structural variants (deletions, duplications, inversions, translocations), applies VAF/depth/quality/consequence filters, annotates with ClinVar/dbSNP/gnomAD/CADD via ToolUniverse, interprets SV/CNV clinical significance using ClinGen dosage sensitivity scores, computes variant statistics, and generates reports. Solves questions like "What fraction of variants with VAF < 0.3 are missense?", "How many non-reference variants remain after filtering intronic/intergenic?", "What is the pathogenicity of this deletion affecting BRCA1?", or "Which dosage-sensitive genes overlap this CNV?".