gabrielmoreira
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- ▌ Platform Custom Metadata Type Generate · gabrielmoreira bundleUse this skill when users need to create, generate, or validate Salesforce Custom Metadata Type metadata — the __mdt object, its fields, and its deployable records. Trigger when users mention custom metadata types, CMDT, __mdt objects, custom metadata records, .md-meta.xml files, or reference/config data that must ship between orgs. Also trigger for admin-maintained mapping, lookup, or crosswalk tables and field mappings ("map fields from A to B", code lookups) — config admins change without a code deploy belongs in a CMDT, never hardcoded in Apex or Flow — and when troubleshooting CMDT record/type deploy errors. DO NOT TRIGGER for Custom Settings — route to platform-custom-setting-generate; for regular custom objects holding business records — use platform-custom-object-generate; or for secrets and API keys — recommend a Named Credential, which this skill never generates.
- ▌ Service Itsm Slack Itservice Configure · gabrielmoreira bundleConfigure the "Set Up Self Service for Employees on Slack" / "Slack for Employee Service" checklist for Employee Service (ITSM) on Slack — the employee side, covering the Slack for Employee Service org preference, Employee Slack Notifications permission-set assignment, employee portal (Digital Experience site) enablement/selection, and connecting Slack to a Preferred Digital Experience Site. Use this for: 'set up Slack for Employee Service', 'assign Employee Slack Notifications permission set', 'manage user access for Slack employee service', 'select a preferred digital experience site for Slack', 'set up self service for employees on Slack', or any request to complete the IT Service / Employee Service half of the Slack ITSM Go page checklist. DO NOT TRIGGER for the Microsoft Teams equivalents (service-itsm-teams-itservice-configure) or for turning ITSM notification preferences on or off.
- ▌ Service Itsm Teams Itservice Configure · gabrielmoreiraConfigure the "Set Up Salesforce IT Service" checklist for Microsoft Teams Employee Service (ITSM) — the employee side, covering app enablement, marketplace install guidance, user access assignment, and Digital Experience Site selection. Use this for: 'turn on Salesforce IT Service', 'set up IT Service on Teams', 'assign Teams for Employee permission set', 'give employees access to Teams for Employee Service', 'manage user access for Teams ITSM', 'grant users the permission sets needed for Teams Employee Service', 'select a digital experience site for Teams', 'install Salesforce IT Service app on Teams', or any request to complete the IT Service half of the Teams ITSM Go page checklist (including the Manage User Access step). DO NOT TRIGGER for the base Teams Salesforce Go page toggle or Azure/Entra app setup (service-itsm-teams-configure) or for the IT Desk/fulfiller half of the checklist (service-itsm-teams-itdesk-configure).
- ▌ Service Omni Service Channel Configure · gabrielmoreira bundleUse to ensure exactly one ServiceChannel exists on a Salesforce org for a routable sObject (Case | Incident | MessagingSession | VoiceCall), reusing any standard or custom channel already bound to that sObject and only deploying a canonical template when none exists. Salesforce enforces one ServiceChannel per RelatedEntity, so the skill detects via the Tooling API first. Standard channels ship for Case (Cases), MessagingSession (sfdc_livemessage), VoiceCall (sfdc_phone); Incident has none. Triggers: configure ServiceChannel for Case/Incident/Messaging/Voice routing, add Incident or Voice routing to Omni. Do not use to tune per-sObject capacity (use PresenceUserConfig.Capacity), to reset a mis-configured channel to canonical shape, or for sObjects outside Case/Incident/MessagingSession/VoiceCall.
- ▌ Service Omni Supervisor Permset Assign · gabrielmoreira bundleUse to assign the Salesforce-shipped standard ContactCenterSupervisor PermissionSet (default) to N existing supervisor users via PermissionSetAssignment DML. Idempotent — SOQL detects existing (user, perm-set) pairs before POST, and DUPLICATE_VALUE is treated as reused. The standard set carries its own permission-set license and assigns cleanly on Service-Cloud-enabled orgs; a user whose license lacks the entitlement surfaces FIELD_INTEGRITY_EXCEPTION so the operator can fix the profile/license. Triggers: assign the supervisor permset, grant supervisor perms, complete supervisor provisioning. Do not use on production orgs or to assign agent permsets.
- ▌ Service Omni Supervisor Surface Deploy · gabrielmoreira bundleUse to populate the Omni-Channel Supervisor action + tab surface on an existing OmniSupervisorConfig by inserting the standard OmniSupervisorConfigAction and OmniSupervisorConfigTab companion rows via the Data API, idempotent (inserts only the missing types). Requires an OmniSupervisorConfig from service-omni-supervisor-config-deploy. Triggers: give the supervisor the standard action buttons and tabs, add Wallboard/Agents/Queues tabs to Omni Supervisor, configure supervisor actions like Change Queues/Skills. Do not use to create the supervisor configuration itself, create supervisor users, assign the supervisor permission set, or add custom-action / FlexiPage / AWS-dashboard / AI-agent surfaces (those need an external reference and must be set up in Setup).
- ▌ Knowledge Steward · gabrielmoreiraAI工作经验知识库管理。适用于用户明确要求'保存到Obsidian'、'记录这个'、'save this insight'、'memo this'、'capture this'等知识沉淀场景。将对话中的提示词、模式、问题修复、想法和效率优化保存到Obsidian知识库,并自动同步到GitHub。
- ▌ Metric Calculator · gabrielmoreiraCompute well-defined metrics from existing formulas, datasets, or test outputs. Use as an explicit/manual helper when the metric definition is already known, not for choosing the overall analysis owner or dashboard strategy.
- ▌ Openalex Database · gabrielmoreiraQuery and analyze scholarly literature using the OpenAlex database. This skill should be used when searching for academic papers, analyzing research trends, finding works by authors or institutions, tracking citations, discovering open access publications, or conducting bibliometric analysis across 240M+ scholarly works. Use for literature searches, research output analysis, citation analysis, and academic database queries.
- ▌ Perplexity Search · gabrielmoreiraPerform AI-powered web searches with real-time information using Perplexity models via LiteLLM and OpenRouter. This skill should be used when conducting web searches for current information, finding recent scientific literature, getting grounded answers with source citations, or accessing information beyond the model knowledge cutoff. Provides access to multiple Perplexity models including Sonar Pro, Sonar Pro Search (advanced agentic search), and Sonar Reasoning Pro through a single OpenRouter API key.
- ▌ Security Reviewer · gabrielmoreiraDedicated security-audit route for OWASP-style risks, secret leaks, auth flaws, injection, unsafe input handling, SSRF/XSS, and sensitive-data exposure. Use instead of code-reviewer when the prompt explicitly asks for security, vulnerability, threat, auth, or OWASP review.
- ▌ Smart File Writer · gabrielmoreiraIntelligent file write error handler: diagnoses permissions, disk space, path length, file locks before retrying. Use when you encounter 'Error writing file', 'Permission denied', 'Access denied', 'No space left', or related file write failures.
- ▌ Diagnose Clickhouse Errors · gabrielmoreiraDiagnose ClickHouse runtime query failures when the user wants database-level cause and fix guidance from an error or numeric error code, not source-code root cause analysis.
- ▌ A11Y Playwright Testing · gabrielmoreira bundleAccessibility testing for web applications using Playwright (@playwright/test), TypeScript, and axe-core. Use to write, run, or debug WCAG 2.2 AA checks, keyboard and focus tests, ARIA/semantic validation, accessible names, form labels, color contrast, or screen-reader test patterns. Keywords: accessibility, WCAG, axe-core, keyboard navigation, focus management, ARIA.
- ▌ Webapp Selenium Testing · gabrielmoreira bundleAuthor and maintain versioned Selenium WebDriver tests with Java and JUnit 5. Use for creating, debugging, or running Selenium specs, implementing Page Objects, handling explicit waits, capturing screenshots, or setting up Maven test projects. Supports Chrome, Firefox, and Edge. Keywords: Selenium WebDriver, Java, JUnit 5, Page Object Model, explicit waits, Maven, screenshots.
- ▌ Card Game · gabrielmoreira bundleBuild a card game: card data, deck/hand/discard zones, draw/shuffle/reshuffle, a turn structure, costs, and effect resolution. Use for a deckbuilder, TCG/CCG, or roguelike deckbuilder.
- ▌ Roguelike · gabrielmoreira bundleBuild a roguelike: turn-based grid movement, procedural dungeons, permadeath, field-of-view, and loot tables. Use for a roguelike/roguelite or turn-based grid dungeon crawler with procedural levels.
- ▌ Judgment Day · gabrielmoreiraTrigger: judgment day, dual review, adversarial review, juzgar. Run explicit blind dual review with at most two scoped fix/re-judgment rounds.
- ▌ Sdd Research · gabrielmoreiraTrigger: SDD research, external evidence, source-backed research. Produce auditable evidence for a selected research lane.
- ▌ Azure Smart City Iot Solution Builder · gabrielmoreira bundleDesign and plan end-to-end Azure IoT and Smart City solutions: requirements, architecture, security, operations, cost, and a phased delivery plan with concrete implementation artifacts.
- ▌ Etf Premium · gabrielmoreiraCalculate ETF premium/discount vs NAV via Yahoo Finance, and decompose single-day surges into NAV-driven vs structural components (gamma squeeze, dealer hedging, blocked AP arbitrage). Use whenever the user asks about an ETF's premium or discount, NAV comparison, why an ETF diverged from its holdings, or how much of a move is dealer-hedging-driven. Triggers: "ETF premium", "ETF discount", "NAV premium", "is SPY at a premium", "BITO premium", "IBIT premium", "bond ETF discount", "trading above/below NAV", "ETF premium screener", "biggest discount", "compare ETF NAV", "ETF arbitrage", "ETF gamma squeeze", "ETF premium surge", "decompose ETF move", "dealer gamma exposure", "GEX for ETF", "why did this ETF jump", "premium convergence", "AP arbitrage blocked", or any request about the gap between an ETF's price and underlying value. Especially relevant for leveraged, inverse, international, bond, commodity, and crypto ETFs.
- ▌ Browser QA · gabrielmoreiraUse when validating or debugging a workflow in the embedded browser and you need a reproducible, evidence-first loop.
- ▌ Bnbchain MCP · gabrielmoreiraBNB Chain MCP server connection and tool usage. Covers npx @bnb-chain/mcp@latest, PRIVATE_KEY and RPC, and every MCP tool — blocks, transactions, contracts, ERC20/NFT transfers, wallet, ERC-8004 agent registration, Greenfield. Use when connecting to bnbchain-mcp, querying or transacting on BNB Chain/opBNB/EVM, registering as ERC-8004 agent, or using Greenfield.
- ▌ Okx Agentic Wallet · gabrielmoreiraOKX Agentic Wallet — the single skill for the user's wallet and on-chain execution. Use it whenever the user wants to operate their wallet or execute an on-chain action, including: login & accounts, balance / holdings, wallet address / deposit / receive, send / transfer, contract calls (approve / deposit / withdraw), transaction history & status, message signing, wallet export & policy; pay gas with a stablecoin (Gas Station, Solana); swap / trade / buy / sell / convert, get a quote; cross-chain bridge & track arrival; limit orders (buy dip / take profit / stop loss / buy above) plus cancel / list / resume them; broadcast / gas / simulate / track a transaction; look up any public address's holdings; security scanning (token / honeypot 蜜罐 / 貔貅, DApp phishing, tx & signature checks, approvals); audit log. Once matched, follow this skill's Intent Routing to dispatch to the exact action.
- ▌ Okx Dapp Discovery · gabrielmoreiraPlugin router for 20 third-party DeFi protocols (Polymarket, Aave, Hyperliquid, PancakeSwap, Morpho, Raydium, Curve, Compound, Pendle, Lido, ether.fi, GMX, Kamino, Orca, Meteora, Clanker, pump.fun, Uniswap) and their protocol-native tokens (HYPE, HLP, eETH, weETH, stETH, wstETH, LDO, GHO, CAKE, CRV, COMP, RAY, ETHFI, GLP, kToken, PT-* / YT-*, $CLANKER). Resolves DApp/token → plugin → confirm-install → re-apply request. Routing only — never signs or broadcasts; every on-chain write needs explicit user approval. Fires on: (1) named DApp + action verb (swap/deposit/stake/long/borrow/buy/sell/snipe/farm/claim, EN or ZH 买/卖/换/存/质押/借/做多/做空/狙击); (2) 2+ DApp comparison ("Aave vs Compound", "Lido vs ether.fi"); (3) Polymarket UpDown (`<COIN> 5min updown`, `5 分钟涨跌`, `预测市场`); (4) protocol-native token + action verb ("deposit USDC into HLP", "PT-stETH on Pendle"); (5) pump.fun WRITE verbs (buy/sell/snipe/ape/swap or 买/卖/狙击/梭哈/帮我买). See body for full rules.
- ▌ Starknet Defi · gabrielmoreiraExecute DeFi operations on Starknet including token swaps via avnu aggregator, DCA recurring buys, STRK staking, and lending/borrowing. Supports gasless transactions.
- ▌ Assets Refresh · gabrielmoreiraRefresh the Unity AssetDatabase. Use after files were added or updated outside of the Unity API, or to force script recompilation when a '.cs' file changed. Returns a processing/success response and waits for compilation when triggered.
- ▌ Package Remove · gabrielmoreiraUninstall a UPM package from the Unity project. Modifies `manifest.json` and may trigger a domain reload — the final result is delivered after the reload via the request's `requestId`. Built-in packages and packages that are dependencies of others cannot be removed. Use 'package-list' to list installed packages first.
- ▌ Package Search · gabrielmoreiraSearch Unity's package registry plus locally installed packages (Git, local, embedded sources) by query string. Returns available versions and installation status. Online mode fetches exact matches from the live registry then supplements with cached substring matches.
- ▌ Profiler Start · gabrielmoreiraEnable Unity's runtime profiler and open the Profiler window. Idempotent: calling when already enabled returns the current enabled state without error.
- ▌ Scene Get Data · gabrielmoreiraRetrieve the list of root GameObjects in the specified opened scene (or the active scene when `openedSceneName` is empty). Supports token-saving path-scoped reads over the root-GameObjects array via `paths` or `viewQuery`. Use 'scene-list-opened' to enumerate scenes.
- ▌ Script Execute · gabrielmoreiraCompiles and executes C# code dynamically using Roslyn. Supports a full-code mode (default) and a body-only mode — see the skill body for the difference and for how to pass Unity object references as parameters.
- ▌ 144 Java Data Oriented Programming · gabrielmoreira bundleUse when you need to apply data-oriented programming best practices in Java — including separating code (behavior) from data structures using records, designing immutable data with pure transformation functions, keeping data flat and denormalized with ID-based references, starting with generic data structures converting to specific types when needed, ensuring data integrity through pure validation functions, and creating flexible generic data access layers. This should trigger for requests such as Improve the code with Data-Oriented Programming; Apply Data-Oriented Programming; Refactor the code with Data-Oriented Programming; Model Java data with records and pure functions; Separate Java behavior from immutable data structures; Validate data integrity with pure Java functions. Part of Plinth Toolkit
- ▌ 706 Technologies Containers Docker · gabrielmoreira bundleUse when you need framework-agnostic Docker and container image guidance for Java projects - Dockerfile design, multi-stage Maven builds, jlink custom runtimes, micro runtime distributions such as Alpaquita, JVM container ergonomics, non-root execution, image metadata, .dockerignore, reproducible builds, vulnerability scanning, SBOM awareness, and production-safe container defaults. This should trigger for requests such as Review Java Dockerfile; Improve Docker image security; Add jlink runtime to a Java container; Add containerization to a Java project; Optimize Java container image size; Review Docker build reproducibility. Part of Plinth Toolkit
- ▌ Sciagent Skill Creator · gabrielmoreiraScaffold a new SciAgent-Skills entry. Picks pipeline/toolkit/database/guide template, creates skills/{category}/{name}/SKILL.md with valid frontmatter, appends the registry.yaml entry, runs validation. Enforces name uniqueness, kebab-case, description keyword rules, schema rules from AGENTS.md. TRIGGER when user says (any language): "add a SciAgent skill", "add a skill for <X>", "create new skill", "create a SKILL.md for <X>", "scaffold a skill", "new skill entry", "register a skill", "신규 skill 추가", "스킬 만들어줘", "스킬 생성", "skill 만들어", or any request to add a new SKILL.md to this repo. ALWAYS invoke this skill BEFORE writing to skills/ or registry.yaml. DO NOT TRIGGER when: editing existing entry's content (just edit the file directly); migrating an existing entry (read AGENTS.md "Migrating from Existing Entries" first); only updating registry.yaml without creating a new SKILL.md.
- ▌ Wow API Currency Economy · gabrielmoreiraComplete reference for WoW Retail Currency, Auction House, Token, Store, Trading Post, Black Market, Mail, and Player Trading APIs. Covers C_CurrencyInfo (currency data, tracking, backpack), Auction House (full listing/bidding/buying/selling/search/commodity), C_WowTokenPublic (WoW Token market), AccountStore (in-game shop), CatalogShop, C_PerksProgram (Trading Post — Trader's Tender), BlackMarket (BMAH), TradeInfo (player trading), MailInfo (mailbox), and related events. Use when working with currencies, auction house UI, WoW Tokens, the in-game store, Trading Post, black market, mail, or player-to-player trading.
- ▌ Wow API Escape Sequences · gabrielmoreiraComplete reference for World of Warcraft UI escape sequences — pipe-character sequences embedded in text strings to produce colors, inline textures, atlas icons, grammar inflections, word-wrap hints, Kstrings, and other special rendering. Use when formatting chat output, tooltip text, FontString content, or any UI text that needs color codes, inline icons, named colors, item-quality colors, texture markup, atlas markup, localized grammar forms, or escape-sequence utilities like WrapTextInColorCode, CreateTextureMarkup, CreateSimpleTextureMarkup, and CreateAtlasMarkup.
- ▌ Wow API Spells Abilities · gabrielmoreiraComplete reference for WoW Retail Spell, SpellBook, ActionBar, Cooldown, Totem, and Shapeshifting APIs. Covers C_Spell info/cooldown/usability/range, C_SpellBook navigation/slot queries, C_ActionBar slot management/state/overrides, C_SpellActivationOverlay procs, C_SpellDiminish DR tracking, C_CooldownViewer, C_AssistedCombat rotation helpers, totem queries, shapeshift forms, casting/channeling functions, flyouts, spell confirmation, and global spell category functions. Use when working with spells, abilities, action bars, cooldowns, casting, totems, shapeshift forms, spell procs, or diminishing returns.
- ▌ Yt Brief · gabrielmoreiraRefine a YouTube video idea into a structured production brief with angle, key points, value proposition, CTA asset, and audience segment. Use this skill whenever the user says "create a brief", "brief this idea", "develop this idea", "write a video brief", "production brief", or has selected a video idea from ideation and wants to define the angle and structure before packaging and outlining. Use when working with yt brief. Trigger with 'yt', 'brief'.
- ▌ Concise Technical Writing · gabrielmoreira bundleWrite, edit, and tighten clear concise technical communication. Use when Codex is asked for commit messages, PR descriptions, changelogs, README sections, design notes, implementation summaries, status updates, release notes, bug reports, comments, or to make text shorter, clearer, less verbose, less AI-sounding, or more direct.
- ▌ Creator Invoice Readiness · gabrielmoreira bundlePrepare creator invoice readiness checklists for sponsor or customer handoff. Use when Codex is asked to check whether an influencer invoice can be sent, organize sponsor invoice fields, payment terms, deliverable proof, approval evidence, usage add-ons, PO/vendor details, tax/accounting review needs, missing fields, or invoice handoff notes.
- ▌ Environment Config Review · gabrielmoreira bundleReview environment configuration for apps, services, CI, deployment, and runtime settings. Use when Codex is asked to inspect env vars, config files, secrets, feature flags, environment parity, config drift, or deployment-specific settings.
- ▌ Prompt Regression Testing · gabrielmoreira bundleDesign reusable prompt regression tests for agent skills and workflows. Use when Codex is asked to prevent a skill from regressing, create prompt test cases, cover known failures, or define repeatable evaluation prompts.
- ▌ Sales Pipeline Management · gabrielmoreira bundleDesign, audit, and improve sales pipeline stages, qualification, CRM hygiene, forecasting, deal reviews, pipeline coverage, stage exit criteria, sales metrics, opportunity management, and revenue operating cadence. Use when Codex is asked about pipeline health, sales process, forecast accuracy, deal stages, CRM fields, sales dashboards, or funnel bottlenecks.
- ▌ Synthetic Character Bible · gabrielmoreira bundlePrepare review-only synthetic character bibles for AI-assisted creator personas, mascots, recurring fictional hosts, virtual influencers, or synthetic spokescharacters. Use when Codex is asked to define a synthetic character's identity, voice, visuals, backstory, boundaries, disclosure rules, likeness and voice risks, provenance notes, prohibited claims, continuity, or production guardrails.
- ▌ Email Automation Builder · gabrielmoreiraBuild multi-sequence email automation flows with branching logic. Triggers on: "build email automation", "create email funnel", "email automation flow", "welcome series with branches", "conditional email sequence", "set up automation", "email workflow builder", "segmented email flow", "advanced email sequence", "nurture funnel", "cart abandonment sequence", "win-back email flow".
- ▌ Git Helper · gabrielmoreiraProvides git workflow assistance, branch management, and commit message optimization
- ▌ AI Assist Observability Audit · gabrielmoreira bundle17-dimension observability audit with tier activation, health scoring, and cost analysis. Covers logging, metrics, tracing, alerting, SLOs, profiling, security observability, and developer experience. Use when assessing observability posture, identifying telemetry gaps, or optimizing observability costs.
- ▌ Sleep Story · gabrielmoreiraWrite stories designed to help listeners fall asleep. Use for bedtime podcasts, meditation content, calming narratives, or any content where the goal is gentle cognitive engagement that fades naturally into rest.
- ▌ Character Arc · gabrielmoreiraDesign and troubleshoot character transformation arcs. Use when characters feel static, when transformation feels unearned or abrupt, when you can't articulate what false belief needs to die, or when characters serve plot without having internal journeys. Covers positive, negative, and flat arcs.
- ▌ Memetic Depth · gabrielmoreiraCreate the perception of cultural depth through strategic juxtaposition of familiar and unfamiliar elements. Use when settings feel shallow, when you need centuries of implied history without exposition, or when worldbuilding lacks the texture of real cultural evolution.
- ▌ Underdog Unit · gabrielmoreiraGenerate stories about institutional outcasts given impossible mandates with minimal resources. Use when you want team dynamics in hostile institutions, David vs. Goliath within organizations, or narrative tension from constraint-driven creativity.
- ▌ Story Collaborator · gabrielmoreiraAct as an active writing partner who contributes content alongside the human writer. Use when the writer wants a collaborator who generates prose, dialogue, alternatives, and builds on their ideas. Applies Story Sense frameworks while actively contributing to the creative work. Contrasts with story-coach which never writes.
- ▌ Genre Conventions · gabrielmoreira bundleDiagnose genre problems and generate genre-specific elements. Use when genre promise is unclear, when elements feel misplaced, when secondary genres compete with primary, or when you need genre-specific entropy. Covers all 11 elemental genres from the Writing Excuses framework.
- ▌ Outline Coach · gabrielmoreiraAct as an assistive outline coach who guides structural development through questions. Use when helping someone develop their own outline through diagnosis and frameworks. Critical constraint - never generate outline content. Instead ask questions, identify structural issues, suggest approaches, and let the writer structure.
- ▌ Web Search Tavily · gabrielmoreira bundleSearch the web using Tavily API for high-quality, AI-optimized results with advanced filtering options. Use when you need structured search results, domain filtering, relevance scores, or AI-generated answer summaries. Requires TAVILY_API_KEY. Keywords: tavily, advanced search, filtered search, domain filtering, relevance scoring.
- ▌ Agile Workflow · gabrielmoreira bundleOrchestrate agile development workflows by invoking commands in sequence with checkpoint-based flow control. This skill should be used when the user asks to 'run the workflow', 'continue working', 'what's next', 'complete the task cycle', 'start my day', 'end the sprint', 'implement the next task', or wants guided step-by-step development assistance. Platform-agnostic git-only workflow without PR integration. Keywords: workflow, orchestrate, agile, task cycle, sprint, daily, implement, review, merge, standup, retrospective, git.
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- ▌ Bio Basecalling · gabrielmoreira bundleConvert raw Nanopore signal data (FAST5/POD5) to nucleotide sequences using Dorado basecaller. Covers model selection, GPU acceleration, modified base detection, and quality filtering. Use when processing raw Nanopore data before alignment. Note: Guppy is deprecated; use Dorado for all new analyses.
- ▌ Bio Variant Calling Deepvariant · gabrielmoreira bundleDeep learning-based variant calling with Google DeepVariant. Provides high accuracy for germline SNPs and indels from Illumina, PacBio, and ONT data. Use when calling variants with DeepVariant deep learning caller or when highest germline calling accuracy is required.
- ▌ Bio Entrez Link · gabrielmoreira bundleFind cross-database references between NCBI databases using Biopython Bio.Entrez (ELink). Use when navigating gene to protein/structure, sequence to publication, PubMed to GEO, BioProject to SRA runs, or discovering all link relationships for a record. Covers linkname semantics, cmd= variants, asymmetric link warnings, neighbor_history for >200 input IDs, and per-database link tables.
- ▌ Bio Causal Genomics Genomic Sem · gabrielmoreira bundleFits structural equation models to GWAS summary statistics using GenomicSEM (Grotzinger 2019), including common-factor models, confirmatory factor models, ESEM, common-factor GWAS with Q_SNP heterogeneity, multivariate Wald tests, and stratified GenomicSEM partitioned heritability. Reconciles results against MTAG multi-trait analysis. Handles sample overlap via the LDSC sampling-covariance matrix, identifies and resolves Heywood cases, and verifies model fit with CFI / RMSEA. Use when modeling latent genetic architecture across correlated traits, running multivariate GWAS on a shared factor, distinguishing factor-mediated from trait-specific SNP effects, or comparing GenomicSEM common-factor results against MTAG when both depend on accurate sampling covariance.
- ▌ Bio Genome Engineering Grna Design · gabrielmoreira bundleDesign guide RNAs for CRISPR-Cas9/Cas12a experiments using CRISPRscan and local scoring algorithms. Score guides for on-target activity using Rule Set 2 and Azimuth models. Use when designing sgRNAs for gene knockout, activation, or repression experiments.
- ▌ Bio Crispr Screens Hit Calling · gabrielmoreira bundleCross-method decision tree for calling hits in pooled CRISPR screens. Catalogs statistical models (MAGeCK RRA, MAGeCK MLE, BAGEL2, drugZ, JACKS, Chronos, CERES), experimental designs each is built for, failure modes outside design domain, reconciliation when methods disagree, multiple-testing and effect-size thresholds, the order of operations (count -> QC -> CN-correct -> hit-call -> validate), the second-best-sgRNA conservative rule, and consensus-hit strategy. Use when choosing among MAGeCK / BAGEL2 / drugZ / JACKS / Chronos for a given design, reconciling disagreement across two or three methods on the same screen, deciding whether to require consensus, gating downstream validation by hit-confidence tier, or interpreting unstable hit lists across reruns.
- ▌ Bio Copy Number Hrd Scoring · gabrielmoreira bundleQuantify homologous recombination deficiency (HRD) from tumor copy number using the three genomic-scar metrics — loss of heterozygosity (LOH), large-scale state transitions (LST), and telomeric allelic imbalance (TAI) — with scarHRD, and via the whole-genome HRDetect and CHORD models. Covers the genomic instability score, the PARP-inhibitor clinical context, whole-genome-doubling correction, and the scar-versus-state distinction. Use when computing an HRD score for PARP-inhibitor eligibility, deriving LOH/LST/TAI scars from allele-specific copy number, deciding between scar-based and mutational-signature HRD methods, or interpreting an HRD result in a BRCA-reverted or low-purity tumor.
- ▌ Bio Local Blast · gabrielmoreira bundleBuild local BLAST databases and run searches using NCBI BLAST+ command-line tools. Use when running >50 queries, building custom databases with -parse_seqids and -taxid, downloading prebuilt NCBI databases via update_blastdb.pl, choosing -task variants (megablast/dc-megablast/blastn/blastn-short), tuning soft/hard masking, scaling threads, or extracting hits with blastdbcmd. Encodes BLAST v5 vs v4 database format, taxonomy filtering, makeblastdb pitfalls.
- ▌ Bio Alignment Msa Parsing · gabrielmoreira bundleParse and analyze multiple sequence alignments using Biopython. Extract sequences, identify conserved regions, analyze gaps, work with annotations, and manipulate alignment data for downstream analysis. Use when parsing or manipulating multiple sequence alignments.
- ▌ Bio Experimental Design Sample Size · gabrielmoreira bundleEstimates required sample sizes for differential expression, ChIP-seq, methylation, and proteomics studies. Use when budgeting experiments, writing grant proposals, or determining minimum replicates needed to achieve statistical significance for expected effect sizes.
- ▌ Bio Splicing Qc · gabrielmoreira bundleAssesses RNA-seq data quality specifically for alternative splicing analysis. QC layers include experimental design audit (library prep, read length, depth, replicates), STAR 2-pass cohort-style alignment, junction saturation curves and discovery plateau detection, novel-vs-known junction ratio diagnostics, junction-overhang distribution, splice-site strength scoring (MaxEntScan intrinsic + SpliceAI context-aware), strandedness verification, GENCODE basic vs comprehensive choice, and rRNA contamination screening. Splicing analysis is more demanding than DGE on read length, depth, library prep, alignment strategy, and annotation choice — failures silently bias PSI estimates and inflate novel-junction false positives. Use when evaluating data suitability for splicing analysis, troubleshooting low event detection, or designing sequencing experiments where AS is a primary endpoint.
- ▌ Bio Data Visualization Upset Plots · gabrielmoreira bundleBuild UpSet plots to visualize set intersections beyond 4 sets (where Venn fails) using ComplexUpset (modern, ggplot2-grammar) or the unmaintained UpSetR, with explicit cardinality vs degree sorting, attribute panels, and query highlighting. Use when comparing overlap across many gene sets, peak sets, variant lists, or any set membership matrix where Venn diagrams become illegible.
- ▌ Borzoi · gabrielmoreiraPredict genome-wide functional tracks (RNA-seq, CAGE, DNase, ChIP) from DNA sequence with Borzoi. Use this skill when: (1) Scoring the regulatory effect of a variant on expression/accessibility, (2) Generating predicted coverage tracks for a locus, (3) Prioritising non-coding variants by predicted track delta.
- ▌ Drugrepobank Query · gabrielmoreira bundleQuery the DrugRepoBank drug repurposing evidence database. Use whenever the user asks about repurposing candidates, drug–disease–target repurposing evidence, or wants to look up any entity (drug name, DrugBank ID, ChEMBL ID, PubChem CID, TTD target ID, UniProt ID, disease name) in DrugRepoBank.
- ▌ Open Targets Platform · gabrielmoreira bundleQuery the Open Targets Platform for drug-target-disease associations. Use whenever the user asks about drug targets, gene-disease associations, drug indications, clinical trial phases, or wants to look up any entity (Ensembl gene ID, ChEMBL drug ID, or free-text gene/drug name) in Open Targets. Also trigger when the user mentions Open Targets, ENSG IDs, CHEMBL IDs, or asks about target prioritization for diseases.
- ▌ Evomath Tao · gabrielmoreiraUse this skill whenever the user submits a non-trivial mathematical claim that needs a rigorous proof or audit. Trigger on IMO/Putnam/USAMO/Olympiad-style problems, ML/AI theoretical statements, research conjectures, suspected-false claims, multi-step proofs the user already failed on, proof drafts with possible hidden assumptions, or any request containing 'prove rigorously', 'verify this', 'is this true', 'find the gap', 'audit my proof', 'find a counterexample', or 'use EvoMath' that targets a mathematical claim. Activate also when the problem requires more than three reasoning steps. Do NOT use for single-step calculations, definition lookups, textbook exercises with a known recipe, code analysis tasks, literature survey questions, pure symbolic manipulation, or non-mathematical applications of those trigger phrases (e.g., 'is it true that GPT-4 can solve math?', 'verify this LaTeX syntax'); hand those back instead.
- ▌ Abide Skill · gabrielmoreiraUse this skill whenever the user wants an end-to-end workflow for the ABIDE (Autism Brain Imaging Data Exchange) dataset, including download, BIDS organization, and processing of sMRI and rs-fMRI data. Triggers include: 'ABIDE', 'ABIDE data', 'process ABIDE', 'ABIDE fMRI', 'ABIDE sMRI', 'autism imaging', or any request to run the ABIDE pipeline. This is the NeuroClaw dataset-orchestration layer for ABIDE.
- ▌ Aomic Skill · gabrielmoreiraUse this skill whenever the user wants an end-to-end workflow for the AOMIC (Amsterdam Open MRI Collection) dataset, including data access, BIDS organization, and multimodal processing of sMRI, rs-fMRI, and task-fMRI. Triggers include: 'AOMIC', 'AOMIC data', 'process AOMIC', 'AOMIC fMRI', 'AOMIC resting state', or any request to run the AOMIC multimodal pipeline. This is the NeuroClaw dataset-orchestration layer for AOMIC.
- ▌ Cobre Skill · gabrielmoreiraUse this skill whenever the user wants an end-to-end workflow for the COBRE dataset, including download, BIDS organization, and processing of sMRI and rs-fMRI data for schizophrenia research. Triggers include: 'COBRE', 'process COBRE', 'COBRE schizophrenia', 'COBRE fMRI', or any request to run the COBRE pipeline. This is the NeuroClaw dataset-orchestration layer for COBRE.
- ▌ Hcpep Skill · gabrielmoreiraUse this skill whenever the user wants an end-to-end workflow for the HCP Early Psychosis (HCP-EP) dataset, including dataset download, BIDS organization, and multimodal processing of sMRI, fMRI, and dMRI. Triggers include: 'HCP Early Psychosis', 'HCP-EP', 'process HCP Early Psychosis data', 'HCP EP sMRI fMRI', or any request to run the HCP-EP multimodal pipeline.
- ▌ Hcpya Skill · gabrielmoreiraUse this skill whenever the user wants an end-to-end workflow for the HCP Young Adult (HCP-YA / HCP1200) dataset, including dataset download, BIDS organization, and multimodal processing of sMRI, fMRI, and dMRI. Triggers include: 'HCP Young Adult', 'HCP-YA', 'HCP1200', 'process HCP data', 'HCP sMRI fMRI DTI', or any request to run the HCP-YA multimodal pipeline.
- ▌ Oasis Skill · gabrielmoreiraUse this skill whenever the user wants an end-to-end workflow for the OASIS (Open Access Series of Imaging Studies) dataset, including BIDS validation, multimodal processing of sMRI, and phenotype extraction for aging and Alzheimer's disease research. Triggers include: 'OASIS', 'OASIS-1', 'OASIS-2', 'OASIS-3', 'process OASIS data', 'Alzheimer', or any request to run the OASIS pipeline.
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- ▌ Nobel Yamanaka · gabrielmoreira诺贝尔奖得主山中伸弥(Shinya Yamanaka)的认知框架。iPS诱导多能干细胞发现者,2012年诺贝尔生理学或医学奖。 核心镜片:临床痛点驱动的减法科学家——从24个因子削减到4个,从外科手术室走向诺贝尔奖。 触发词:「山中伸弥」「Yamanaka」「iPS细胞」「减法思维」「临床驱动研究」「化繁为简」。 调研来源:15+一手来源(Nobel官方、Cell论文、CiRA官网、多个采访),6个研究文件。 心智模型:4个 | 决策启发式:7条 | 诚实边界:5条
- ▌ Bio Assembly Qc · gabrielmoreira bundleAssemble genomes/metagenomes and produce assembly QC artifacts.
- ▌ Crossref Lookup · gabrielmoreira bundleQuery the Crossref REST API for DOI validation, title search, citation metadata, and bibliography audits. Use when you need DOI lookup, title-to-DOI matching, or reference metadata cleanup.
- ▌ Proposal Review · gabrielmoreiraStructured, decision-ready review framework for AI/ML, computational biology, and bioscience proposals. Use when evaluating grant, project, or funding proposals.
- ▌ Cell Segmentation Skills Index · gabrielmoreira bundleCell and nucleus segmentation tools for microscopy images. Covers Cellpose, SAM-based methods, StarDist, InstanSeg, and Mesmer.
- ▌ Ena Database · gabrielmoreiraENA REST API for sequences, reads, assemblies, and annotations. Portal API search, Browser API retrieval (XML/FASTA/EMBL), file reports for FASTQ/BAM URLs, taxonomy, cross-refs. For multi-DB Python use bioservices; for NCBI-only use pubmed-database or Biopython Entrez.
- ▌ Pdb Database · gabrielmoreiraQuery RCSB PDB (200K+ structures) via the public REST + GraphQL APIs with plain `requests` (no SDK). Search by text, attribute, sequence, or 3D structure similarity (Search API); retrieve metadata via GraphQL (Data API); download PDB/mmCIF from files.rcsb.org. For AlphaFold predictions use alphafold-database-access; for protein sequences only use uniprot-protein-database.
- ▌ Sar Analysis · gabrielmoreiraStructure-activity relationship (SAR) analysis guide for drug discovery including molecular descriptor analysis, scaffold analysis, and activity cliff detection.
- ▌ Data Integrity Post Batch · gabrielmoreiraValidates and scores a batch of up to 50 contact records in a single request. Each record is processed independently — one item failing does not affect others. Returns per-item email, phone, and text validation results with quality scores, normalized values, plus batch-level aggregates including total, valid_count, invalid_count, and average_quality_score.
- ▌ Email Validate Post Email · gabrielmoreiraValidates a single email address and returns a full breakdown of syntax validity, MX record status, disposable domain check, normalized form, and any typo suggestion.
- ▌ Exchange Rate Get Convert · gabrielmoreiraConverts an amount from one currency to another and returns the rate alongside the converted value.
- ▌ Global Data Get Country · gabrielmoreiraRetrieve working days, public holidays, and next upcoming holiday for any country and optional year/month. Covers 100+ countries.
- ▌ Identity Risk Post Verify · gabrielmoreiraDeep-verify an email address using domain-level signals including WHOIS age, MX records, and domain availability. Optional IP check. Use for high-value or suspicious accounts.
- ▌ Unit Conversion Get Units · gabrielmoreiraReturns all available unit conversion types grouped by measurement category
- ▌ World Time Get Timezone · gabrielmoreiraReturns the current time for the given IANA timezone identifier. The timezone is supplied as a path parameter (e.g. `America/New_York`, `Europe/London`, `UTC`).