Lord1Egypt
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- ▌ Beautifulsoup Scraping · lord1egyptParsing HTML web structures, searching tags, and extracting text using BeautifulSoup4.
- ▌ Crispr Screen Analysis · lord1egyptCRISPR genetic screen analysis using MAGeCK, CRISPRclean, and crispy. Use for pooled CRISPR knockout/activation screens, sgRNA count normalization, gene essentiality scoring, hit calling, pathway enrichment, and QC of CRISPR screen data. Supports both positive and negative selection screens.
- ▌ Data Tool Use Concepts · lord1egyptConceptual foundations of tool use with the Claude API including tool definitions, tool choice, and best practices
- ▌ Labarchive Integration · lord1egypt bundleElectronic lab notebook API integration. Access notebooks, manage entries/attachments, backup notebooks, integrate with Protocols.io/Jupyter/REDCap, for programmatic ELN workflows.
- ▌ Markdown Documentation · lord1egyptStructuring technical markdown docs, wikis, and building clean developer layout grids.
- ▌ Python Requests Client · lord1egyptPerforming synchronous HTTP requests, managing sessions, passing headers, and query parameters using Requests.
- ▌ Skill Computer Use MCP · lord1egyptInstructions for using computer-use MCP tools including tool selection tiers, app access tiers, link safety, and financial action restrictions
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- ▌ Get Available Resources · lord1egypt bundleThis skill should be used at the start of any computationally intensive scientific task to detect and report available system resources (CPU cores, GPUs, memory, disk space). It creates a JSON file with resource information and strategic recommendations that inform computational approach decisions such as whether to use parallel processing (joblib, multiprocessing), out-of-core computing (Dask, Zarr), GPU acceleration (PyTorch, JAX), or memory-efficient strategies. Use this skill before running analyses, training models, processing large datasets, or any task where resource constraints matter.
- ▌ Iso 13485 Certification · lord1egypt bundleComprehensive toolkit for preparing ISO 13485 certification documentation for medical device Quality Management Systems. Use when users need help with ISO 13485 QMS documentation, including (1) conducting gap analysis of existing documentation, (2) creating Quality Manuals, (3) developing required procedures and work instructions, (4) preparing Medical Device Files, (5) understanding ISO 13485 requirements, or (6) identifying missing documentation for medical device certification. Also use when users mention medical device regulations, QMS certification, FDA QMSR, EU MDR, or need help with quality system documentation.
- ▌ Market Research Reports · lord1egypt bundleGenerate comprehensive market research reports (50+ pages) in the style of top consulting firms (McKinsey, BCG, Gartner). Features professional LaTeX formatting, extensive visual generation with scientific-schematics and generate-image, deep integration with research-lookup for data gathering, and multi-framework strategic analysis including Porter Five Forces, PESTLE, SWOT, TAM/SAM/SOM, and BCG Matrix.
- ▌ Ngs Pipeline Management · lord1egyptNext-generation sequencing pipeline management with Snakemake and Nextflow. Use for building, running, and debugging reproducible NGS workflows for RNA-seq, WGS, ChIP-seq, ATAC-seq, and amplicon sequencing. Covers pipeline design patterns, HPC/cloud execution, containerization, and workflow optimization.
- ▌ Protocolsio Integration · lord1egypt bundleIntegration with protocols.io API for managing scientific protocols. This skill should be used when working with protocols.io to search, create, update, or publish protocols; manage protocol steps and materials; handle discussions and comments; organize workspaces; upload and manage files; or integrate protocols.io functionality into workflows. Applicable for protocol discovery, collaborative protocol development, experiment tracking, lab protocol management, and scientific documentation.
- ▌ Audio Intelligence · lord1egyptNative audio understanding, transcription, speech tone analysis, sound classification, and multi-speaker transcription.
- ▌ Data Anthropic CLI · lord1egyptReference documentation for the ant CLI covering installation, authentication, command structure, input and output shaping, managed agents workflows, and scripting patterns
- ▌ Git Workflow Utils · lord1egyptAdvanced git operations including branching, commits, merge conflicts, tag creation, and history manipulation.
- ▌ Image Optimization · lord1egyptResizing, compressing formats, and applying image filters using Pillow.
- ▌ Logging Monitoring · lord1egyptConfiguring Python logging library, formatting streams, and managing rotating logs.
- ▌ Playwright Browser · lord1egyptAutomated headless web browser testing, page interactions, screenshot capture, and web scraping.
- ▌ Prometheus Metrics · lord1egyptInstrumenting system diagnostics, counting requests, and exporting metrics to Prometheus monitoring systems.
- ▌ Scholar Evaluation · lord1egypt bundleSystematically evaluate scholarly work using the ScholarEval framework, providing structured assessment across research quality dimensions including problem formulation, methodology, analysis, and writing with quantitative scoring and actionable feedback.
- ▌ Scientific Writing · lord1egypt bundleCore skill for the deep research and writing tool. Write scientific manuscripts in full paragraphs (never bullet points). Use two-stage process with (1) section outlines with key points using research-lookup then (2) convert to flowing prose. IMRAD structure, citations (APA/AMA/Vancouver), figures/tables, reporting guidelines (CONSORT/STROBE/PRISMA), for research papers and journal submissions.
- ▌ Skill Verify Skill · lord1egyptSkill for opinionated verification workflow for validating code changes.
- ▌ Websockets Network · lord1egyptAsynchronous bi-directional WebSocket client and server configuration in Python.
- ▌ Citation Management · lord1egypt bundleComprehensive citation management for academic research. Search Google Scholar and PubMed for papers, extract accurate metadata, validate citations, and generate properly formatted BibTeX entries. This skill should be used when you need to find papers, verify citation information, convert DOIs to BibTeX, or ensure reference accuracy in scientific writing.
- ▌ Proteomics Analysis · lord1egyptMass spectrometry-based proteomics data analysis with pyteomics, spectrum_utils, and MaxQuant/DIA-NN output processing. Use for peptide identification, protein quantification (LFQ, TMT, SILAC), differential expression, PTM analysis, and proteomics data visualization. Covers both DDA and DIA proteomics workflows.
- ▌ Pydantic Validation · lord1egyptData validation, data parsing, configuration management, and type coercion using Pydantic.
- ▌ Regular Expressions · lord1egyptDesigning, parsing, and searching string parameters using Python regular expressions.
- ▌ Semantic Versioning · lord1egyptConfiguring release versions, package numbering schemes, and tracking dependency compatibilities.
- ▌ Stripe Payments API · lord1egyptIntegrating Stripe payments, managing subscription billing checkout sessions, and validation signatures on webhooks.
- ▌ Claude System Prompt · lord1egyptOperational rules, safety instructions, reasoning guidelines, and behavioral patterns from the Claude 3.7 Sonnet system prompt.
- ▌ Dnanexus Integration · lord1egypt bundleDNAnexus cloud genomics platform. Build apps/applets, manage data (upload/download), dxpy Python SDK, run workflows, FASTQ/BAM/VCF, for genomics pipeline development and execution.
- ▌ Docker Compose Utils · lord1egyptConfiguring, spinning up, and orchestrating multi-container local runtime environments with Docker Compose.
- ▌ Latchbio Integration · lord1egypt bundleLatch platform for bioinformatics workflows. Build pipelines with Latch SDK, @workflow/@task decorators, deploy serverless workflows, LatchFile/LatchDir, Nextflow/Snakemake integration.
- ▌ Linux Bash Scripting · lord1egyptWriting automation scripts, file directory operations, and loop controls in Linux Bash shell.
- ▌ Neuropixels Analysis · lord1egypt bundleNeuropixels neural recording analysis. Load SpikeGLX/OpenEphys data, preprocess, motion correction, Kilosort4 spike sorting, quality metrics, Allen/IBL curation, AI-assisted visual analysis, for Neuropixels 1.0/2.0 extracellular electrophysiology. Use when working with neural recordings, spike sorting, extracellular electrophysiology, or when the user mentions Neuropixels, SpikeGLX, Open Ephys, Kilosort, quality metrics, or unit curation.
- ▌ Neuroscience Imaging · lord1egyptNeuroimaging data analysis with nilearn, nibabel, and fMRIPrep outputs. Use for fMRI/MRI data loading, brain atlas parcellation, functional connectivity analysis, GLM-based task fMRI, resting-state network analysis, and publication-quality brain visualizations. Covers structural MRI, task fMRI, and rs-fMRI workflows.
- ▌ Statistical Analysis · lord1egypt bundleGuided statistical analysis with test selection and reporting. Use when you need help choosing appropriate tests for your data, assumption checking, power analysis, and APA-formatted results. Best for academic research reporting, test selection guidance. For implementing specific models programmatically use statsmodels.
- ▌ Benchling Integration · lord1egypt bundleBenchling R&D platform integration. Access registry (DNA, proteins), inventory, ELN entries, workflows via API, build Benchling Apps, query Data Warehouse, for lab data management automation.
- ▌ Climate Data Analysis · lord1egyptClimate and Earth system data analysis using xarray, cartopy, cfgrib, and CMIP6/ERA5 datasets. Use for loading NetCDF/GRIB climate data, computing climatologies, spatial aggregation, anomaly detection, bias correction, and publication-quality climate maps. Best for atmospheric, oceanic, and land surface data analysis.
- ▌ Hypothesis Generation · lord1egypt bundleStructured hypothesis formulation from observations. Use when you have experimental observations or data and need to formulate testable hypotheses with predictions, propose mechanisms, and design experiments to test them. Follows scientific method framework. For open-ended ideation use scientific-brainstorming; for automated LLM-driven hypothesis testing on datasets use hypogenic.
- ▌ Metabolomics Analysis · lord1egyptUntargeted and targeted metabolomics data analysis using pyMZML, mzTab-M processing, and metabolite identification. Use for LC-MS/GC-MS feature detection, metabolite annotation, differential metabolite analysis, pathway mapping, and metabolic flux visualization. Covers XCMS-compatible workflows in Python.
- ▌ Opentrons Integration · lord1egypt bundleOfficial Opentrons Protocol API for OT-2 and Flex robots. Use when writing protocols specifically for Opentrons hardware with full access to Protocol API v2 features. Best for production Opentrons protocols, official API compatibility. For multi-vendor automation or broader equipment control use pylabrobot.
- ▌ Pandas Data Wrangling · lord1egyptCleaning, filtering, merging, and aggregating massive tabular data structures using Pandas.
- ▌ Performance Profiling · lord1egyptMeasuring CPU performance metrics and memory bottlenecks in Python code blocks.
- ▌ Search Grounding · lord1egyptReal-time Google Search grounding, live web query integration, and web source citation extraction.
- ▌ Security Headers · lord1egyptImplementing Content Security Policy (CSP), CORS, and essential security headers in web server responses.
- ▌ Flask Restful API · lord1egyptStructuring clean, resource-based HTTP REST endpoints using Flask and Flask-RESTful routing.
- ▌ Github Actions CI · lord1egyptConfiguring GitHub Actions workflows for continuous integration, testing, and deployment automation.
- ▌ Literature Review · lord1egypt bundleConduct comprehensive, systematic literature reviews using multiple academic databases (PubMed, arXiv, bioRxiv, Semantic Scholar, etc.). This skill should be used when conducting systematic literature reviews, meta-analyses, research synthesis, or comprehensive literature searches across biomedical, scientific, and technical domains. Creates professionally formatted markdown documents and PDFs with verified citations in multiple citation styles (APA, Nature, Vancouver, etc.).
- ▌ Omero Integration · lord1egypt bundleMicroscopy data management platform. Access images via Python, retrieve datasets, analyze pixels, manage ROIs/annotations, batch processing, for high-content screening and microscopy workflows.
- ▌ Omics Integration · lord1egyptMulti-omics data integration using MOFA+, DIABLO, and MixOmics for combining genomics, transcriptomics, proteomics, metabolomics, and epigenomics datasets. Use for identifying shared variation across omics layers, building integrative biomarker models, and discovering cross-modal biological patterns. Best for paired multi-omics cohort studies.
- ▌ PDF Parsing Utils · lord1egyptExtracting structured text tables and content blocks from PDF files using PyPDF or pdfplumber.
- ▌ Pydantic Settings · lord1egyptManaging environment variables, validating system configurations, and parsing .env configurations using Pydantic Settings.
- ▌ Scientific Slides · lord1egypt bundleBuild slide decks and presentations for research talks. Use this for making PowerPoint slides, conference presentations, seminar talks, research presentations, thesis defense slides, or any scientific talk. Provides slide structure, design templates, timing guidance, and visual validation. Works with PowerPoint and LaTeX Beamer.
- ▌ Stable Baselines3 · lord1egypt bundleProduction-ready reinforcement learning algorithms (PPO, SAC, DQN, TD3, DDPG, A2C) with scikit-learn-like API. Use for standard RL experiments, quick prototyping, and well-documented algorithm implementations. Best for single-agent RL with Gymnasium environments. For high-performance parallel training, multi-agent systems, or custom vectorized environments, use pufferlib instead.
- ▌ Structured Output · lord1egyptStructured data extraction using Pydantic schemas, strict JSON output formats, and schema validation.
- ▌ Treatment Plans · lord1egypt bundleGenerate concise (3-4 page), focused medical treatment plans in LaTeX/PDF format for all clinical specialties. Supports general medical treatment, rehabilitation therapy, mental health care, chronic disease management, perioperative care, and pain management. Includes SMART goal frameworks, evidence-based interventions with minimal text citations, regulatory compliance (HIPAA), and professional formatting. Prioritizes brevity and clinical actionability.
- ▌ Venue Templates · lord1egypt bundleAccess comprehensive LaTeX templates, formatting requirements, and submission guidelines for major scientific publication venues (Nature, Science, PLOS, IEEE, ACM), academic conferences (NeurIPS, ICML, CVPR, CHI), research posters, and grant proposals (NSF, NIH, DOE, DARPA). This skill should be used when preparing manuscripts for journal submission, conference papers, research posters, or grant proposals and need venue-specific formatting requirements and templates.
- ▌ Cellxgene Census · lord1egypt bundleQuery the CELLxGENE Census (61M+ cells) programmatically. Use when you need expression data across tissues, diseases, or cell types from the largest curated single-cell atlas. Best for population-scale queries, reference atlas comparisons. For analyzing your own data use scanpy or scvi-tools.
- ▌ Clinical Reports · lord1egypt bundleWrite comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), and patient documentation (SOAP, H&P, discharge summaries). Full support with templates, regulatory compliance (HIPAA, FDA, ICH-GCP), and validation tools.
- ▌ Cryptography API · lord1egyptSymmetric/asymmetric encryption, hashing, password salting, and message verification via cryptography library.
- ▌ Function Calling · lord1egyptRegistering custom Python tools, handling parallel function calls, and executing callback routines.
- ▌ Multimodal Video · lord1egyptNative video understanding, event timestamping, frame sampling, and video narrative generation.
- ▌ Nextjs Framework · lord1egyptBuilding modern React web applications with Server-Side Rendering (SSR), API routes, and routing layouts in Next.js.
- ▌ Optimize For Gpu · lord1egypt bundleGPU-accelerate Python code using CuPy, Numba CUDA, Warp, cuDF, cuML, cuGraph, KvikIO, cuCIM, cuxfilter, cuVS, cuSpatial, and RAFT. Use whenever the user mentions GPU/CUDA/NVIDIA acceleration, or wants to speed up NumPy, pandas, scikit-learn, scikit-image, NetworkX, GeoPandas, or Faiss workloads. Covers physics simulation, differentiable rendering, mesh ray casting, particle systems (DEM/SPH/fluids), vector/similarity search, GPUDirect Storage file IO, interactive dashboards, geospatial analysis, medical imaging, and sparse eigensolvers. Also use when you see CPU-bound Python code (loops, large arrays, ML pipelines, graph analytics, image processing) that would benefit from GPU acceleration, even if not explicitly requested.
- ▌ Resend Email API · lord1egyptSending programmatic, HTML transactional emails with custom domains using Resend.
- ▌ Usfiscaldata · lord1egypt bundleQuery the U.S. Treasury Fiscal Data API for federal financial data including national debt, government spending, revenue, interest rates, exchange rates, and savings bonds. Access 54 datasets and 182 data tables with no API key required. Use when working with U.S. federal fiscal data, national debt tracking (Debt to the Penny), Daily Treasury Statements, Monthly Treasury Statements, Treasury securities auctions, interest rates on Treasury securities, foreign exchange rates, savings bonds, or any U.S. government financial statistics.
- ▌ Nginx Routing · lord1egyptConfiguring Nginx reverse proxy routing, load balancers, rate limits, and SSL termination.
- ▌ Open Notebook · lord1egypt bundleSelf-hosted, open-source alternative to Google NotebookLM for AI-powered research and document analysis. Use when organizing research materials into notebooks, ingesting diverse content sources (PDFs, videos, audio, web pages, Office documents), generating AI-powered notes and summaries, creating multi-speaker podcasts from research, chatting with documents using context-aware AI, searching across materials with full-text and vector search, or running custom content transformations. Supports 16+ AI providers including OpenAI, Anthropic, Google, Ollama, Groq, and Mistral with complete data privacy through self-hosting.
- ▌ Prisma Orm DB · lord1egyptType-safe database ORM management, migrations, and CRUD operations using Prisma in Node.js or Python.
- ▌ RAG Vector DB · lord1egyptRetrieval-Augmented Generation implementation using vector databases, embedding models, and query routines.
- ▌ Redis Caching · lord1egyptDistributed key-value caching, session storage, and rate limiting with Upstash or standard Redis.
- ▌ Skill Run App · lord1egyptSkill for launching and driving the current project's app through its real runtime surface using project-specific run skills or fallback patterns
- ▌ Vite Frontend · lord1egyptInitializing, structuring, and bundling client-side Single-Page Applications (SPA) with Vite.
- ▌ AWS S3 Storage · lord1egyptUploading, downloading, and managing static file assets in Amazon Web Services S3 Buckets using Boto3.
- ▌ Code Execution · lord1egyptEnabling Gemini's native sandboxed Python runtime, capturing code outputs, and mathematical/scientific executions.
- ▌ Email Delivery · lord1egyptRouting transactional user emails via SMTP, Resend, or SendGrid APIs in Python.
- ▌ Generate Image · lord1egypt bundleGenerate or edit images using AI models (FLUX, Nano Banana 2). Use for general-purpose image generation including photos, illustrations, artwork, visual assets, concept art, and any image that is not a technical diagram or schematic. For flowcharts, circuits, pathways, and technical diagrams, use the scientific-schematics skill instead.
- ▌ JWT Auth Utils · lord1egyptGenerating, signing, and validating JSON Web Tokens (JWT) for secure REST APIs and user sessions.
- ▌ Context Caching · lord1egyptLarge context caching, cached token management, TTL config, and cost optimization.
- ▌ Cron Scheduling · lord1egyptScheduling recurring scripts, parsing crontab syntax, and implementing scheduled background loops.
- ▌ Database Lookup · lord1egypt bundleSearch 78 public scientific, biomedical, materials science, and economic databases via REST APIs. Covers physics/astronomy (NASA, NIST, SDSS, SIMBAD), earth/environment (USGS, NOAA, EPA), chemistry/drugs (PubChem, ChEMBL, DrugBank, FDA, KEGG, ZINC, BindingDB), materials (Materials Project, COD), biology/genomics (Reactome, UniProt, STRING, Ensembl, NCBI Gene, GEO, GTEx, PDB, AlphaFold, InterPro, BioGRID, Gene Ontology, dbSNP, gnomAD, ENCODE, Human Protein Atlas, Human Cell Atlas), disease/clinical (COSMIC, Open Targets, ClinicalTrials.gov, OMIM, ClinVar, GDC/TCGA, cBioPortal, DisGeNET, GWAS Catalog), regulatory (FDA, USPTO, SEC EDGAR), economics/finance (FRED, World Bank, US Treasury), demographics (US Census, Eurostat, WHO). Use when looking up compounds, genes, proteins, pathways, variants, clinical trials, patents, economic indicators, or any public database API query.
- ▌ Express Routing · lord1egyptBuilding Express web server endpoints, routing HTTP requests, and configuring server middlewares in Node.js.
- ▌ GRAPHQL Queries · lord1egyptConstructing GraphQL query client configurations and mutation payloads in Python.
- ▌ Hugging Science · lord1egypt bundleUse when the user is doing AI/ML work in a scientific domain — biology, chemistry, physics, astronomy, climate, genomics, materials science, medicine, ecology, energy, conservation, engineering, mathematics, scientific reasoning, drug discovery, protein design, weather modeling, theorem proving, single-cell, PDE solving, or anything similar. Hugging Science (huggingscience.co) is a curated catalog of scientific datasets, models, blog posts, and interactive Spaces; the `hugging-science` org on Hugging Face hosts community datasets, models, and demo Spaces. This skill helps you discover the right resource AND actually use it — loading datasets via `datasets`, running models via `transformers` or the HF Inference API, calling Spaces like BoltzGen via `gradio_client`, and citing blog posts for methodology. Trigger this skill whenever a user mentions a scientific ML task, asks for "a dataset/model for X" where X is a scientific topic, wants to fine-tune on scientific data, asks about protein / molecule / genome /
- ▌ Python Unittest · lord1egyptWriting test cases, assertions, mocking API calls, and running test runner pipelines using unittest.
- ▌ Research Grants · lord1egypt bundleWrite competitive research proposals for NSF, NIH, DOE, DARPA, and Taiwan NSTC. Agency-specific formatting, review criteria, budget preparation, broader impacts, significance statements, innovation narratives, and compliance with submission requirements.
- ▌ Research Lookup · lord1egypt bundleLook up current research information using parallel-cli search (primary, fast web search), the Parallel Chat API (deep research), or Perplexity sonar-pro-search (academic paper searches). Automatically routes queries to the best backend. Use for finding papers, gathering research data, and verifying scientific information. Note: query text is transmitted to api.parallel.ai (PARALLEL_API_KEY) and, for academic searches, to openrouter.ai (OPENROUTER_API_KEY).
- ▌ Scikit Survival · lord1egypt bundleComprehensive toolkit for survival analysis and time-to-event modeling in Python using scikit-survival. Use this skill when working with censored survival data, performing time-to-event analysis, fitting Cox models, Random Survival Forests, Gradient Boosting models, or Survival SVMs, evaluating survival predictions with concordance index or Brier score, handling competing risks, or implementing any survival analysis workflow with the scikit-survival library.
- ▌ Skill Debugging · lord1egyptInstructions for debugging an issue that the user is encountering in the Claude Code session
- ▌ Sqlite Database · lord1egyptQuerying, migrating, and writing relational tables inside embedded SQLite databases.
- ▌ Tailwind Design · lord1egyptConfiguring and structuring styling components with utility-first CSS classes in HTML or JSX.
- ▌ Scvi Tools · lord1egypt bundleDeep generative models for single-cell omics. Use when you need probabilistic batch correction (scVI), transfer learning, differential expression with uncertainty, or multi-modal integration (TOTALVI, MultiVI). Best for advanced modeling, batch effects, multimodal data. For standard analysis pipelines use scanpy.
- ▌ Umap Learn · lord1egypt bundleUMAP dimensionality reduction. Fast nonlinear manifold learning for 2D/3D visualization, clustering preprocessing (HDBSCAN), supervised/parametric UMAP, for high-dimensional data.
- ▌ Bioservices · lord1egypt bundleUnified Python interface to 40+ bioinformatics services. Use when querying multiple databases (UniProt, KEGG, ChEMBL, Reactome) in a single workflow with consistent API. Best for cross-database analysis, ID mapping across services. For quick single-database lookups use gget; for sequence/file manipulation use biopython.
- ▌ Peer Review · lord1egypt bundleStructured manuscript/grant review with checklist-based evaluation. Use when writing formal peer reviews with specific criteria methodology assessment, statistical validity, reporting standards compliance (CONSORT/STROBE), and constructive feedback. Best for actual review writing, manuscript revision. For evaluating claims/evidence quality use scientific-critical-thinking; for quantitative scoring frameworks use scholar-evaluation.
- ▌ Statsmodels · lord1egypt bundleStatistical models library for Python. Use when you need specific model classes (OLS, GLM, mixed models, ARIMA) with detailed diagnostics, residuals, and inference. Best for econometrics, time series, rigorous inference with coefficient tables. For guided statistical test selection with APA reporting use statistical-analysis.
- ▌ Supabase DB · lord1egyptInteracting with Supabase databases, user authentication, and storage buckets using the Python client.
- ▌ Zarr Python · lord1egypt bundleChunked N-D arrays for cloud storage. Compressed arrays, parallel I/O, S3/GCS integration, NumPy/Dask/Xarray compatible, for large-scale scientific computing pipelines.