Binder Design Campaign · spyfighting bundle Gated protein design campaign: each expert judgement is a checkpoint a human signs off before compute is spent. Branches: de novo binder design (epitope choice, generation, co-folding ensemble ranking, ranked order sheet); structure and complex prediction with calibrated confidence; protein engineering (stability, enzyme, interface). Fires on designing binders or miniproteins, picking an epitope or hotspots, running RFdiffusion, BindCraft, BoltzGen, ProteinMPNN, ESMFold2 or Protenix, computing ipSAE or DockQ, ranking designs to order, auditing such a campaign, or 蛋白结合子设计, 表位选择, 结构预测.
