← all publishers

synthetic-sciences

@synthetic-sciences source repo

363 published skills · page 4 of 4

  1. Optimizing Attention Flash · synthetic-sciences bundle
    Optimizes transformer attention with Flash Attention for 2-4x speedup and 10-20x memory reduction. Use when training/running transformers with long sequences (>512 tokens), encountering GPU memory issues with attention, or need faster inference. Supports PyTorch native SDPA, flash-attn library, H100 FP8, and sliding window attention.
    0
    installs
  2. Model Economics · synthetic-sciences
    Cost modeling and ROI analysis for specialized LLM development. Use when deciding whether to train a custom model, estimating total cost, or calculating break-even vs frontier APIs. Covers training costs, inference costs, and time-to-ROI projections.
    0
    installs
  3. Astronomy Inference · synthetic-sciences
    Carries astronomical data from file to posterior with the conventions the field expects, covering astropy units, coordinates, FITS, WCS and Time with barycentric corrections, photometric systems and magnitude arithmetic, period finding with the astropy Lomb-Scargle periodogram and its false-alarm levels, Bayesian parameter estimation with emcee and nested sampling with dynesty, convergence diagnostics such as autocorrelation time and R-hat, uncertainty propagation through samples, and explicit reporting of priors. Use for light curves, photometry, spectroscopy, orbit or transit fits and any astronomical parameter estimation; use astropy for plain library usage and bayesian-inference for non-astronomical models.
    0
    installs
  4. Symbolic Regression · synthetic-sciences
    Discover governing equations from data using PySR (evolutionary symbolic regression). Physics-constrained search with dimensional analysis, custom operators, and complexity-accuracy tradeoffs. Use when you need an interpretable equation, not a black-box model.
    0
    installs
  5. Research Workflows · synthetic-sciences bundle
    Execute the planning, code-review, comparison and export workflows behind the /plan, /review, /compare and /export commands as state machines over OpenScience session state, artifacts and compute. Internal support skill; reproduction, source audits and peer review are the reproduce, sources and peer-review core skills.
    0
    installs
  6. Curated Bio Datasets · synthetic-sciences bundle
    Guide to accessing curated biological datasets for computational biology. COSMIC cancer data, GTEx expression, GWAS catalog, GeneBass exome variants, BioGRID interactions, MSigDB gene sets, DisGeNET disease-gene associations, and GO ontology. For specific database APIs use individual database skills (cosmic-database, gwas-database, etc.).
    0
    installs
  7. Genomic Intelligence · synthetic-sciences bundle
    Predict regulatory features, gene structure, and expression directly from DNA sequence using Genomic Intelligence's hosted transformer DNA language models — no local GPU or model weights. Six tasks over a REST API and a hosted MCP server (keyless public demo): promoter regions, splice donor/acceptor sites, enhancer activity, chromatin state, sequence-to-expression (log TPM), and de-novo gene annotation, plus a composite find-genes-then-predict-expression workflow. Use when the user has a gene symbol, a genomic region, or a DNA/FASTA sequence and wants any of these predictions, mentions Genomic Intelligence, genomicintelligence.ai, api.genomicintelligence.ai, or mcp.genomicintelligence.ai.
    0
    installs
  8. Neuropixels Analysis · synthetic-sciences bundle
    Neuropixels neural recording analysis. Load SpikeGLX/OpenEphys data, preprocess, motion correction, Kilosort4 spike sorting, quality metrics, Allen/IBL curation, AI-assisted visual analysis, for Neuropixels 1.0/2.0 extracellular electrophysiology. Use when working with neural recordings, spike sorting, extracellular electrophysiology, or when the user mentions Neuropixels, SpikeGLX, Open Ephys, Kilosort, quality metrics, or unit curation.
    0
    installs
  9. Molecular Dynamics · synthetic-sciences bundle
    Run and analyze molecular dynamics simulations with OpenMM and MDAnalysis. Set up protein/small molecule systems, define force fields, run energy minimization and production MD, analyze trajectories (RMSD, RMSF, contact maps, free energy surfaces). For structural biology, drug binding, and biophysics.
    0
    installs
  10. Alphafold Database · synthetic-sciences bundle
    Access AlphaFold 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.
    0
    installs
  11. Datacommons Client · synthetic-sciences bundle
    Work with Data Commons, a platform providing programmatic access to public statistical data from global sources. Use this skill when working with demographic data, economic indicators, health statistics, environmental data, or any public datasets available through Data Commons. Applicable for querying population statistics, GDP figures, unemployment rates, disease prevalence, geographic entity resolution, and exploring relationships between statistical entities.
    0
    installs
  12. Fred Economic Data · synthetic-sciences bundle
    Query FRED (Federal Reserve Economic Data) API for 800,000+ economic time series from 100+ sources. Access GDP, unemployment, inflation, interest rates, exchange rates, housing, and regional data. Use for macroeconomic analysis, financial research, policy studies, economic forecasting, and academic research requiring U.S. and international economic indicators.
    0
    installs
  13. Colab Finetuning · synthetic-sciences bundle
    Fine-tune LLMs on Google Colab GPUs directly from openscience. Connects to Colab runtimes via WebSocket bridge for remote training with Unsloth. Supports SFT, GRPO, DPO, vision, and TTS workflows on free T4 to Pro A100 GPUs.
    0
    installs
  14. Dimensional Analysis · synthetic-sciences
    Automated dimensional analysis — Buckingham Pi theorem, non-dimensionalization, unit validation with pint, and characteristic scale estimation. Use before any physics computation to verify consistency and reduce parameter space.
    0
    installs
  15. Sindy Identification · synthetic-sciences
    Sparse Identification of Nonlinear Dynamics (SINDy) — discover governing equations from time-series data. Builds sparse dynamical system models dx/dt = f(x) from measurements using PySINDy. Use when you have trajectory data and want to find the underlying ODE.
    0
    installs
  16. Experimental Design · synthetic-sciences bundle
    Design experiments and studies BEFORE data is collected — choosing a design, randomizing, blocking, and laying out treatment combinations so results are interpretable. Use whenever someone is planning a study, asks how to assign subjects/samples to groups, mentions randomization, blocking, stratification, controls, factorial or fractional-factorial designs, design of experiments (DOE), screening many factors, response-surface optimization, crossover or repeated-measures or split-plot designs, cluster/group randomization, Latin squares, plate layouts, batch/run-order effects, replication vs. pseudoreplication, or sequential/adaptive/group-sequential designs. Trigger even for informal phrasings like "how should I set up this experiment", "how do I avoid confounding", "what's the best way to test these 6 factors", or "assign these mice to conditions". For computing the sample size or power once the design is chosen, use statistical-power; for analyzing data already collected, use statistical-analysis.
    0
    installs
  17. Protein Binder Design · synthetic-sciences
    Design and validate de novo protein binders with the current NVIDIA BioNeMo Agent Toolkit workflow, while adapting honestly when NVIDIA-hosted credentials are unavailable.
    0
    installs
  18. Atomistic Workflows · synthetic-sciences
    Sets up and reports atomistic calculations so they are reproducible and converged, covering ASE Atoms, calculators, optimizers and MD drivers, pymatgen structures, symmetry analysis and the Materials Project API, LAMMPS and GROMACS input basics for molecular dynamics, convergence tests for k-points, plane-wave cutoffs and timesteps, the unit system each code uses, energy-minimization stopping criteria, and archiving of exact input files. Use for DFT, classical or machine-learned potential simulations of molecules, crystals, surfaces and liquids; use molecular-dynamics for biomolecular trajectory analysis and pymatgen for detailed library usage.
    0
    installs
  19. Iso Standards Readiness · synthetic-sciences bundle
    Prepares and structurally reviews readiness evidence for ISO management-system and laboratory-competence standards - ISO 13485 medical device QMS, ISO 14971 device risk management, ISO/IEC 17025 testing and calibration laboratories, and ISO 15189 medical laboratories. Use when organizing declared scope, controlled documents, risk-management files, scope of accreditation, traceability, CAPA, external-provider controls, or bounded local evidence manifests, and when separating ISO certification from laboratory accreditation, FDA QMSR inspection, CLIA certification, MDSAP, and EU MDR/IVDR evidence boundaries. Not for legal applicability, compliance, certification, or accreditation decisions; contains no clause text.
    0
    installs
  20. Hamiltonian Mechanics · synthetic-sciences
    Hamiltonian mechanics — symplectic integrators (leapfrog, Yoshida), Hamilton's equations, Poisson brackets, canonical transformations, action-angle variables, and KAM theory analysis. Use for energy-conserving long-time integration of conservative systems.
    0
    installs
  21. Physics Visualization · synthetic-sciences
    Publication-quality physics plots — vector fields, streamlines, contour maps, 3D surfaces, phase space, spectrograms, and animations. Optimized for journal submission with LaTeX labels, proper colormaps, and multi-panel layouts.
    0
    installs
  22. Statistical Mechanics · synthetic-sciences
    Monte Carlo simulation for statistical mechanics — Ising model, Metropolis-Hastings, Wolff cluster algorithm, observables (magnetization, susceptibility, specific heat), finite-size scaling, and critical phenomena analysis.
    0
    installs
  23. Uncertainty And Units · synthetic-sciences bundle
    Track physical units and propagate measurement uncertainty in scientific calculations using pint and uncertainties. Use for unit conversion and dimensional checking, GUM uncertainty budgets, Type A and Type B evaluation, coverage factors and expanded uncertainty, Monte Carlo propagation, significant-figure and plus-minus reporting, error propagation through curve fits, CODATA constants, auditing Python code for stripped units or broken uncertainty propagation, and order-of-magnitude plausibility checks using dimensionless groups (Reynolds, Peclet, Damkohler, Knudsen, Biot, Womersley), characteristic scales such as diffusion time or Debye length, and observed magnitude ranges. Trigger on "is this number physically reasonable", "sanity check these units", "what regime is this flow in", or a result that looks off by orders of magnitude.
    0
    installs
  24. Protein Diagram · synthetic-sciences bundle
    Publication-quality protein analysis diagrams. Domain architecture maps, secondary structure annotation, Ramachandran plots, contact maps, multiple sequence alignment visualization, and protein feature tracks.
    0
    installs
  25. Structure Prediction · synthetic-sciences bundle
    Protein structure prediction from sequence. ESMFold-based, single GPU, no MSA needed. Predicts 3D structures with pLDDT confidence scores for drug discovery targets.
    0
    installs
  26. Imaging Data Commons · synthetic-sciences bundle
    Query and download public cancer imaging data from NCI Imaging Data Commons using idc-index. Use for accessing large-scale radiology (CT, MR, PET) and pathology datasets for AI training or research. No authentication required. Query by metadata, visualize in browser, check licenses.
    0
    installs
  27. Opentargets Database · synthetic-sciences bundle
    Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs, for therapeutic target identification.
    0
    installs
  28. Weights And Biases · synthetic-sciences bundle
    Track ML experiments with automatic logging, visualize training in real-time, optimize hyperparameters with sweeps, and manage model registry with W&B - collaborative MLOps platform
    0
    installs
  29. Flow Cytometry Analysis · synthetic-sciences bundle
    Complete flow cytometry analysis pipeline. FCS file handling, compensation, manual/automated gating, immunophenotyping, CFSE proliferation analysis, cell cycle analysis (Dean-Jett-Fox), and apoptosis assays. Extends flowio with analytical workflows. For raw FCS parsing only use flowio.
    0
    installs
  30. Sentence Transformers · synthetic-sciences bundle
    Framework for state-of-the-art sentence, text, and image embeddings. Provides 5000+ pre-trained models for semantic similarity, clustering, and retrieval. Supports multilingual, domain-specific, and multimodal models. Use for generating embeddings for RAG, semantic search, or similarity tasks. Best for production embedding generation.
    0
    installs
  31. Prime Intellect · synthetic-sciences
    Safely inspect Prime Intellect identity and plan compute or training workflows using the installed prime CLI and current official documentation.
    0
    installs
  32. Dna Visualization · synthetic-sciences bundle
    Publication-quality DNA/RNA visualizations. Plasmid maps (circular/linear), sequence logos, restriction enzyme maps, GC content plots, and gene feature annotation tracks from GenBank/FASTA.
    0
    installs
  33. Cancer Genomics Analysis · synthetic-sciences bundle
    Computational cancer genomics workflows. Somatic mutation detection and annotation, structural variation characterization, copy number analysis, tumor purity/ploidy estimation, NMF metagene extraction, and DNA damage response network analysis. For cancer mutation databases use cosmic-database; for variant clinical significance use clinvar-database.
    0
    installs
  34. Molecular Optimization · synthetic-sciences bundle
    Iterative lead optimization with analyze-reason-generate-verify-evaluate loop. Paper-backed (MT-Mol, DrugR, MultiMol).
    0
    installs
  35. Molecule Visualization · synthetic-sciences bundle
    Publication-quality molecular visualization. 2D structure drawings (PNG/SVG), molecule grids with property annotations, scaffold highlighting, protein-ligand interaction diagrams, and interactive 3D views.
    0
    installs
  36. Exploratory Data Analysis · synthetic-sciences bundle
    Analyze scientific data files across 200+ formats at the depth the user requests. Detect file type, assess structure, quality, and statistics, and create reports or visualizations only when they are requested or materially needed. Covers chemistry, bioinformatics, microscopy, spectroscopy, proteomics, metabolomics, and general scientific data formats.
    0
    installs
  37. Market Research Reports · synthetic-sciences bundle
    Generate comprehensive market research reports (50+ pages) in the style of top consulting firms (McKinsey, BCG, Gartner). Features professional LaTeX formatting, extensive visual generation with scientific-schematics and generate-image, deep integration with research-lookup for data gathering, and multi-framework strategic analysis including Porter's Five Forces, PESTLE, SWOT, TAM/SAM/SOM, and BCG Matrix.
    0
    installs
  38. Statistical Conventions · synthetic-sciences
    Chooses and reports statistical tests the way a careful referee expects, deciding paired versus unpaired and parametric versus rank-based from the design, using ordered-trend tests such as Jonckheere-Terpstra and Cochran-Armitage for dose or grade levels, correcting for multiple comparisons with Bonferroni, Holm or Benjamini-Hochberg and showing raw and adjusted p-values side by side, giving effect sizes such as Cohen's d, Cliff's delta and odds ratios with confidence intervals, bootstrapping intervals when no formula applies, and stating checked assumptions, exact p-values and degrees of freedom. Use whenever an analysis will report a p-value, a group difference, a trend across ordered categories or a correlation; use statistical-power for sample-size planning and experimental-design for laying out the study.
    0
    installs
  39. Markdown Mermaid Writing · synthetic-sciences bundle
    Comprehensive markdown and Mermaid diagram writing skill. Use when creating any scientific document, report, analysis, or visualization. Establishes text-based diagrams as the default documentation standard with full style guides (markdown + mermaid), 24 diagram type references, and 9 document templates.
    0
    installs
  40. Clinical Decision Support · synthetic-sciences bundle
    Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports (evidence-based guidelines with decision algorithms). Supports GRADE evidence grading, statistical analysis (hazard ratios, survival curves, waterfall plots), biomarker integration, and regulatory compliance. Outputs publication-ready LaTeX/PDF format optimized for drug development, clinical research, and evidence synthesis.
    0
    installs
  41. Folklore Variant Evidence · synthetic-sciences bundle
    Retrieve ClinGen gene-disease validity assertions for a public gene or disease, and review source-linked public evidence and literature for one supported GRCh38 germline nuclear SNV or simple indel through Folklore Clinical Variant Interpretation MCP. Use when a scientific agent must branch deterministically on resolved, ambiguous, not-found, invalid, unsupported, or unavailable variant outcomes; chain a resolved public variant into related literature or publication details; or preserve evidence provenance without accepting patient, phenotype, family, segregation, or private case data.
    0
    installs
  42. Relsa Severity Assessment · synthetic-sciences bundle
    Multivariate severity assessment and humane endpoint prediction for laboratory animal studies using the RELSA (RELative Severity Assessment) score and ARIMA-based foRcast forecasting. Use when combining welfare readouts — body weight or weight loss, body temperature, clinical or nesting scores, biomarkers, activity, heart rate, burrowing, wheel running — into one severity score per animal per day, when asking which animals are at risk of reaching a humane endpoint or when one will be reached, when defining attention/danger zones or thresholds on a severity scale by kernel density estimation, or when reporting severity for a 3Rs, refinement, animal-welfare, or EU Directive 2010/63/EU severity-assessment context. Covers directionality ("turned" variables), baseline normalization, reference sets, RELSA weights, ARIMA prediction intervals, and RMSE/PICP/MPIW evaluation.
    0
    installs
  43. Clinicaltrials Database · synthetic-sciences bundle
    Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research and patient matching.
    0
    installs
  44. LLM As Judge Evaluation · synthetic-sciences bundle
    Evaluate LLM outputs using frontier models as judges. Use for pairwise model comparison, quality scoring with custom rubrics, and automated evaluation pipelines. Covers position bias mitigation, statistical significance, and generating preference data for DPO/RLHF.
    0
    installs
  45. Speculative Decoding · synthetic-sciences bundle
    Accelerate LLM inference using speculative decoding, Medusa multiple heads, and lookahead decoding techniques. Use when optimizing inference speed (1.5-3.6× speedup), reducing latency for real-time applications, or deploying models with limited compute. Covers draft models, tree-based attention, Jacobi iteration, parallel token generation, and production deployment strategies.
    0
    installs
  46. Tinker Training Cost · synthetic-sciences bundle
    Calculates training costs for Tinker fine-tuning jobs. Use when estimating costs for Tinker LLM training, counting tokens in datasets, or comparing Tinker model training prices. Tokenizes datasets using the correct model tokenizer and provides accurate cost estimates.
    0
    installs
  47. Ontology Term Resolution · synthetic-sciences bundle
    Resolve free-text scientific labels to ontology term IDs and validate existing CURIEs against the EBI Ontology Lookup Service (OLS4). Also look up prefixes in Bioregistry, resolve compact identifiers via Identifiers.org, map lab shorthand with ZOOMA, and build Ontobee term pages. Use whenever an ontology identifier must be produced or checked - annotating tissue, cell type, disease, phenotype, assay, chemical, organism, sex, or developmental stage fields; preparing metadata for GEO, ENA, BioSamples, CELLxGENE, HCA, or ISA-Tab submission; auditing a metadata table of term IDs; checking whether a term is obsolete and what replaced it; or deciding HPO vs HP. Triggers include "ontology term", "ontology ID", "CURIE", "controlled vocabulary", "UBERON", "CL:", "MONDO", "HPO", "EFO", "ChEBI", "NCBITaxon", "GO term", "PATO", "Zooma", "Bioregistry", "Identifiers.org", "Ontobee", "annotate this tissue/cell type/disease", and any request to emit or verify an identifier shaped like PREFIX:0001234.
    0
    installs
  48. Training Data Pipeline · synthetic-sciences bundle
    Build training datasets for LLM specialization from production data, frontier model distillation, and synthetic bootstrapping. Use when formatting production logs into SFT data, distilling from frontier APIs, or preparing data for fine-tuning. Covers JSONL formatting, data quality validation, deduplication, and train/eval splitting.
    0
    installs
  49. Conservation Law Discovery · synthetic-sciences
    Discover conserved quantities and symmetries from trajectory data. Identifies energy, momentum, angular momentum, and custom invariants using neural networks and symbolic methods. Inspired by Noether's theorem.
    0
    installs
  50. Multi Objective Optimization · synthetic-sciences bundle
    Pareto-aware molecular design balancing multiple ADMET properties simultaneously. Based on MultiMol (Yu 2025) and MOLLM (Ran 2025).
    0
    installs
  51. Hugging Face Tool Builder · synthetic-sciences bundle
    Use this skill when the user wants to build tool/scripts or achieve a task where using data from the Hugging Face API would help. This is especially useful when chaining or combining API calls or the task will be repeated/automated. This Skill creates a reusable script to fetch, enrich or process data.
    0
    installs
  52. Hugging Face Evaluation · synthetic-sciences bundle
    Add and manage evaluation results in Hugging Face model cards. Supports extracting eval tables from README content, importing scores from Artificial Analysis API, and running custom model evaluations with vLLM/lighteval. Works with the model-index metadata format.
    0
    installs
  53. Ml Benchmark Evaluation · synthetic-sciences
    Rigorous methodology for evaluating ML models on established benchmarks. Covers proper train/val/test splits, baseline verification from original papers, exact metric formula discrepancies, data-leak detection checklist, multi-seed robustness, and honest reporting templates. Use when claiming to beat published baselines, writing methods papers, or auditing existing results.
    0
    installs
  54. Hugging Face Paper Publisher · synthetic-sciences bundle
    Publish and manage research papers on Hugging Face Hub. Supports creating paper pages, linking papers to models/datasets, claiming authorship, and generating professional markdown-based research articles.
    0
    installs
  55. Pathogen Variant Surveillance · synthetic-sciences bundle
    Query live pathogen genomic surveillance data through the GenSpectrum LAPIS API to find which viral lineages are circulating now, how fast they are growing, and what mutations they carry. Use whenever a question depends on the current state of a pathogen population rather than on remembered facts - which SARS-CoV-2 variant is dominant, whether a Pango lineage is still designated or has been withdrawn, what clade or genotype of H5N1 is in a host or region, whether a PCR primer or assay target still matches circulating sequence, or how a lineage's prevalence has moved week to week. Triggers include "variant surveillance", "genomic surveillance", "what variant is circulating", "dominant variant", "Pango lineage", "lineage prevalence", "growth advantage", "SARS-CoV-2 variant", "XFG", "clade 2.3.4.4b", "H5N1 genotype", "influenza clade", "RSV/mpox/measles/dengue lineage", "CoV-Spectrum", "LAPIS", "Nextclade", "pango-designation", and any request to report what a pathogen population looks like today.
    0
    installs
  56. Cheminformatics Definitions · synthetic-sciences
    Pins down the RDKit definitions that differ between conventions before computing molecular descriptors, including Lipinski donor and acceptor counts (Lipinski.NumHDonors and NumHAcceptors versus rdMolDescriptors.CalcNumLipinskiHBD and HBA), TPSA with or without sulfur and phosphorus, QED weighting, standard versus non-standard InChI and InChIKey, standardization order (cleanup, salt stripping, uncharging, tautomer canonicalization), canonical versus isomeric SMILES and aromaticity models, and states which definition produced each number. Use whenever a task computes, filters or compares small-molecule properties or identifiers; use the rdkit skill for general API usage and medchem or admet skills for interpretation.
    0
    installs
  57. Analytical Method Validation · synthetic-sciences bundle
    Plan, execute, and document validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP <1220>/<1225>/<1226>, ICH M10 bioanalytical, CLSI EP, or ISO/IEC 17025. Use for HPLC, LC-MS/MS, GC, CE, ICP-MS, dissolution, qNMR, qPCR, NIR, and ligand binding or cell-based assays whenever the question is whether a procedure is fit for its intended purpose. Triggers include "method validation", "analytical method validation", "AMV", "validation protocol", "acceptance criteria", "linearity", "reportable range", "accuracy and precision", "repeatability", "intermediate precision", "recovery", "LOD", "LOQ", "detection limit", "quantitation limit", "specificity", "robustness", "method transfer", "method comparison", "Deming", "Passing-Bablok", "Bland-Altman", "equivalence testing", "OOS investigation", "ICH Q2", "Q2(R2)", "Q14", "USP 1225", "ICH M10", "incurred sample reanalysis", "ISR", "CLSI EP", and any request to show that an assay works.
    0
    installs
  58. Hdf5 Pde Data Loading · synthetic-sciences
    Patterns for loading PDE simulation datasets (PDEBench, PhiFlow, JAX-CFD) from HDF5 files. Handles layout detection (single tensor vs separate variables), spatial/temporal downsampling, multi-variable systems, HuggingFace and DaRUS data sources, and efficient PyTorch DataLoader creation. Use when preparing PDE data for neural operator training.
    0
    installs
  59. Hugging Face Datasets · synthetic-sciences bundle
    Create and manage datasets on Hugging Face Hub. Supports initializing repos, defining configs/system prompts, streaming row updates, and SQL-based dataset querying/transformation. Designed to work alongside HF MCP server for comprehensive dataset workflows.
    0
    installs
  60. Hugging Face Model Trainer · synthetic-sciences bundle
    This skill should be used when users want to train or fine-tune language models using TRL (Transformer Reinforcement Learning) on Hugging Face Jobs infrastructure. Covers SFT, DPO, GRPO and reward modeling training methods, plus GGUF conversion for local deployment. Includes guidance on the TRL Jobs package, UV scripts with PEP 723 format, dataset preparation and validation, hardware selection, cost estimation, Trackio monitoring, Hub authentication, and model persistence. Should be invoked for tasks involving cloud GPU training, GGUF conversion, or when users mention training on Hugging Face Jobs without local GPU setup.
    0
    installs
  61. Autoregressive Neural Pde Solver · synthetic-sciences
    Training patterns for autoregressive neural PDE solvers (FNO, DeepONet, CNO). Covers rollout training, noise injection for stability, multi-component loss functions (H1, frequency-sensitive, boundary-aware), per-channel normalization for coupled multi-variable systems, and the PDEBench nRMSE metric. Use when training any neural operator that predicts time-dependent PDE solutions.
    0
    installs
  62. Shock Capturing Neural Operators · synthetic-sciences
    Architectures and techniques for neural operators on discontinuous PDE solutions (shocks, contact discontinuities, steep gradients). Covers local-global spectral design (ShockFNO), reflection padding for non-periodic BCs, resolution scaling for shock width, and frequency-band error diagnostics. Use for low-viscosity Burgers, compressible Euler, Riemann problems, or any PDE where standard FNO produces Gibbs oscillations.
    0
    installs
  63. Metabolomics Workbench Database · synthetic-sciences bundle
    Access NIH Metabolomics Workbench via REST API (4,200+ studies). Query metabolites, RefMet nomenclature, MS/NMR data, m/z searches, study metadata, for metabolomics and biomarker discovery.
    0
    installs