← all publishers

TimLai666

@timlai666 source repo

Report this profile Claim this profile

• 258 skills
• 0 followers
• 1 repo stars
• 3 weeks ago last updated

1. ▌
   Requesting Code Review · timlai666 bundle

   Use when completing tasks, implementing major features, or before merging to verify work meets requirements
   1 repo stars
2. ▌
   Flowio · timlai666 bundle

   Parse FCS (Flow Cytometry Standard) files v2.0-3.1. Extract events as NumPy arrays, read metadata/channels, convert to CSV/DataFrame, for flow cytometry data preprocessing.
   1 repo stars
3. ▌
   Geniml · timlai666 bundle

   This skill should be used when working with genomic interval data (BED files) for machine learning tasks. Use for training region embeddings (Region2Vec, BEDspace), single-cell ATAC-seq analysis (scEmbed), building consensus peaks (universes), or any ML-based analysis of genomic regions. Applies to BED file collections, scATAC-seq data, chromatin accessibility datasets, and region-based genomic feature learning.
   1 repo stars
4. ▌
   Pathml · timlai666 bundle

   Full-featured computational pathology toolkit. Use for advanced WSI analysis including multiplexed immunofluorescence (CODEX, Vectra), nucleus segmentation, tissue graph construction, and ML model training on pathology data. Supports 160+ slide formats. For simple tile extraction from H&E slides, histolab may be simpler.
   1 repo stars
5. ▌
   Plotly · timlai666 bundle

   Interactive visualization library. Use when you need hover info, zoom, pan, or web-embeddable charts. Best for dashboards, exploratory analysis, and presentations. For static publication figures use matplotlib or scientific-visualization.
   1 repo stars
6. ▌
   Polars · timlai666 bundle

   Fast in-memory DataFrame library for datasets that fit in RAM. Use when pandas is too slow but data still fits in memory. Lazy evaluation, parallel execution, Apache Arrow backend. Best for 1-100GB datasets, ETL pipelines, faster pandas replacement. For larger-than-RAM data use dask or vaex.
   1 repo stars
7. ▌
   Adaptyv · timlai666 bundle

   Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.
   1 repo stars
8. ▌
   Anndata · timlai666 bundle

   Data structure for annotated matrices in single-cell analysis. Use when working with .h5ad files or integrating with the scverse ecosystem. This is the data format skill—for analysis workflows use scanpy; for probabilistic models use scvi-tools; for population-scale queries use cellxgene-census.
   1 repo stars
9. ▌
   Astropy · timlai666 bundle

   Comprehensive Python library for astronomy and astrophysics. This skill should be used when working with astronomical data including celestial coordinates, physical units, FITS files, cosmological calculations, time systems, tables, world coordinate systems (WCS), and astronomical data analysis. Use when tasks involve coordinate transformations, unit conversions, FITS file manipulation, cosmological distance calculations, time scale conversions, or astronomical data processing.
   1 repo stars
10. ▌
    Cobrapy · timlai666 bundle

    Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.
    1 repo stars
11. ▌
    Datamol · timlai666 bundle

    Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery including SMILES parsing, standardization, descriptors, fingerprints, clustering, 3D conformers, parallel processing. Returns native rdkit.Chem.Mol objects. For advanced control or custom parameters, use rdkit directly.
    1 repo stars
12. ▌
    Denario · timlai666 bundle

    Multiagent AI system for scientific research assistance that automates research workflows from data analysis to publication. This skill should be used when generating research ideas from datasets, developing research methodologies, executing computational experiments, performing literature searches, or generating publication-ready papers in LaTeX format. Supports end-to-end research pipelines with customizable agent orchestration.
    1 repo stars
13. ▌
    Lamindb · timlai666 bundle

    This skill should be used when working with LaminDB, an open-source data framework for biology that makes data queryable, traceable, reproducible, and FAIR. Use when managing biological datasets (scRNA-seq, spatial, flow cytometry, etc.), tracking computational workflows, curating and validating data with biological ontologies, building data lakehouses, or ensuring data lineage and reproducibility in biological research. Covers data management, annotation, ontologies (genes, cell types, diseases, tissues), schema validation, integrations with workflow managers (Nextflow, Snakemake) and MLOps platforms (W&B, MLflow), and deployment strategies.
    1 repo stars
14. ▌
    Matchms · timlai666 bundle

    Spectral similarity and compound identification for metabolomics. Use for comparing mass spectra, computing similarity scores (cosine, modified cosine), and identifying unknown compounds from spectral libraries. Best for metabolite identification, spectral matching, library searching. For full LC-MS/MS proteomics pipelines use pyopenms.
    1 repo stars
15. ▌
    Medchem · timlai666 bundle

    Medicinal chemistry filters. Apply drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, complexity metrics, for compound prioritization and library filtering.
    1 repo stars
16. ▌
    Molfeat · timlai666 bundle

    Molecular featurization for ML (100+ featurizers). ECFP, MACCS, descriptors, pretrained models (ChemBERTa), convert SMILES to features, for QSAR and molecular ML.
    1 repo stars
17. ▌
    Pydicom · timlai666 bundle

    Python library for working with DICOM (Digital Imaging and Communications in Medicine) files. Use this skill when reading, writing, or modifying medical imaging data in DICOM format, extracting pixel data from medical images (CT, MRI, X-ray, ultrasound), anonymizing DICOM files, working with DICOM metadata and tags, converting DICOM images to other formats, handling compressed DICOM data, or processing medical imaging datasets. Applies to tasks involving medical image analysis, PACS systems, radiology workflows, and healthcare imaging applications.
    1 repo stars
18. ▌
    Arboreto · timlai666 bundle

    Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.
    1 repo stars
19. ▌
    Deepchem · timlai666 bundle

    Molecular ML with diverse featurizers and pre-built datasets. Use for property prediction (ADMET, toxicity) with traditional ML or GNNs when you want extensive featurization options and MoleculeNet benchmarks. Best for quick experiments with pre-trained models, diverse molecular representations. For graph-first PyTorch workflows use torchdrug; for benchmark datasets use pytdc.
    1 repo stars
20. ▌
    Diffdock · timlai666 bundle

    Diffusion-based molecular docking. Predict protein-ligand binding poses from PDB/SMILES, confidence scores, virtual screening, for structure-based drug design. Not for affinity prediction.
    1 repo stars
21. ▌
    Fluidsim · timlai666 bundle

    Framework for computational fluid dynamics simulations using Python. Use when running fluid dynamics simulations including Navier-Stokes equations (2D/3D), shallow water equations, stratified flows, or when analyzing turbulence, vortex dynamics, or geophysical flows. Provides pseudospectral methods with FFT, HPC support, and comprehensive output analysis.
    1 repo stars
22. ▌
    Histolab · timlai666 bundle

    Lightweight WSI tile extraction and preprocessing. Use for basic slide processing tissue detection, tile extraction, stain normalization for H&E images. Best for simple pipelines, dataset preparation, quick tile-based analysis. For advanced spatial proteomics, multiplexed imaging, or deep learning pipelines use pathml.
    1 repo stars
23. ▌
    Networkx · timlai666 bundle

    Comprehensive toolkit for creating, analyzing, and visualizing complex networks and graphs in Python. Use when working with network/graph data structures, analyzing relationships between entities, computing graph algorithms (shortest paths, centrality, clustering), detecting communities, generating synthetic networks, or visualizing network topologies. Applicable to social networks, biological networks, transportation systems, citation networks, and any domain involving pairwise relationships.
    1 repo stars
24. ▌
    Pydeseq2 · timlai666 bundle

    Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.
    1 repo stars
25. ▌
    Pyhealth · timlai666 bundle

    Comprehensive healthcare AI toolkit for developing, testing, and deploying machine learning models with clinical data. This skill should be used when working with electronic health records (EHR), clinical prediction tasks (mortality, readmission, drug recommendation), medical coding systems (ICD, NDC, ATC), physiological signals (EEG, ECG), healthcare datasets (MIMIC-III/IV, eICU, OMOP), or implementing deep learning models for healthcare applications (RETAIN, SafeDrug, Transformer, GNN).
    1 repo stars
26. ▌
    Pymatgen · timlai666 bundle

    Materials science toolkit. Crystal structures (CIF, POSCAR), phase diagrams, band structure, DOS, Materials Project integration, format conversion, for computational materials science.
    1 repo stars
27. ▌
    Pyopenms · timlai666 bundle

    Complete mass spectrometry analysis platform. Use for proteomics workflows feature detection, peptide identification, protein quantification, and complex LC-MS/MS pipelines. Supports extensive file formats and algorithms. Best for proteomics, comprehensive MS data processing. For simple spectral comparison and metabolite ID use matchms.
    1 repo stars
28. ▌
    Biopython · timlai666 bundle

    Comprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Best for batch processing, custom bioinformatics pipelines, BLAST automation. For quick lookups use gget; for multi-service integration use bioservices.
    1 repo stars
29. ▌
    Deeptools · timlai666 bundle

    NGS analysis toolkit. BAM to bigWig conversion, QC (correlation, PCA, fingerprints), heatmaps/profiles (TSS, peaks), for ChIP-seq, RNA-seq, ATAC-seq visualization.
    1 repo stars
30. ▌
    Geopandas · timlai666 bundle

    Python library for working with geospatial vector data including shapefiles, GeoJSON, and GeoPackage files. Use when working with geographic data for spatial analysis, geometric operations, coordinate transformations, spatial joins, overlay operations, choropleth mapping, or any task involving reading/writing/analyzing vector geographic data. Supports PostGIS databases, interactive maps, and integration with matplotlib/folium/cartopy. Use for tasks like buffer analysis, spatial joins between datasets, dissolving boundaries, clipping data, calculating areas/distances, reprojecting coordinate systems, creating maps, or converting between spatial file formats.
    1 repo stars
31. ▌
    Hypogenic · timlai666 bundle

    Automated LLM-driven hypothesis generation and testing on tabular datasets. Use when you want to systematically explore hypotheses about patterns in empirical data (e.g., deception detection, content analysis). Combines literature insights with data-driven hypothesis testing. For manual hypothesis formulation use hypothesis-generation; for creative ideation use scientific-brainstorming.
    1 repo stars
32. ▌
    Neurokit2 · timlai666 bundle

    Comprehensive biosignal processing toolkit for analyzing physiological data including ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use this skill when processing cardiovascular signals, brain activity, electrodermal responses, respiratory patterns, muscle activity, or eye movements. Applicable for heart rate variability analysis, event-related potentials, complexity measures, autonomic nervous system assessment, psychophysiology research, and multi-modal physiological signal integration.
    1 repo stars
33. ▌
    Pennylane · timlai666 bundle

    Hardware-agnostic quantum ML framework with automatic differentiation. Use when training quantum circuits via gradients, building hybrid quantum-classical models, or needing device portability across IBM/Google/Rigetti/IonQ. Best for variational algorithms (VQE, QAOA), quantum neural networks, and integration with PyTorch/JAX/TensorFlow. For hardware-specific optimizations use qiskit (IBM) or cirq (Google); for open quantum systems use qutip.
    1 repo stars
34. ▌
    Pufferlib · timlai666 bundle

    High-performance reinforcement learning framework optimized for speed and scale. Use when you need fast parallel training, vectorized environments, multi-agent systems, or integration with game environments (Atari, Procgen, NetHack). Achieves 2-10x speedups over standard implementations. For quick prototyping or standard algorithm implementations with extensive documentation, use stable-baselines3 instead.
    1 repo stars
35. ▌
    Etetoolkit · timlai666 bundle

    Phylogenetic tree toolkit (ETE). Tree manipulation (Newick/NHX), evolutionary event detection, orthology/paralogy, NCBI taxonomy, visualization (PDF/SVG), for phylogenomics.
    1 repo stars
36. ▌
    Markitdown · timlai666 bundle

    Convert files and office documents to Markdown. Supports PDF, DOCX, PPTX, XLSX, images (with OCR), audio (with transcription), HTML, CSV, JSON, XML, ZIP, YouTube URLs, EPubs and more.
    1 repo stars
37. ▌
    Matplotlib · timlai666 bundle

    Low-level plotting library for full customization. Use when you need fine-grained control over every plot element, creating novel plot types, or integrating with specific scientific workflows. Export to PNG/PDF/SVG for publication. For quick statistical plots use seaborn; for interactive plots use plotly; for publication-ready multi-panel figures with journal styling, use scientific-visualization.
    1 repo stars
38. ▌
    Pylabrobot · timlai666 bundle

    Vendor-agnostic lab automation framework. Use when controlling multiple equipment types (Hamilton, Tecan, Opentrons, plate readers, pumps) or needing unified programming across different vendors. Best for complex workflows, multi-vendor setups, simulation. For Opentrons-only protocols with official API, opentrons-integration may be simpler.
    1 repo stars
39. ▌
    Bioservices · timlai666 bundle

    Unified Python interface to 40+ bioinformatics services. Use when querying multiple databases (UniProt, KEGG, ChEMBL, Reactome) in a single workflow with consistent API. Best for cross-database analysis, ID mapping across services. For quick single-database lookups use gget; for sequence/file manipulation use biopython.
    1 repo stars
40. ▌
    Paper 2 Web · timlai666 bundle

    This skill should be used when converting academic papers into promotional and presentation formats including interactive websites (Paper2Web), presentation videos (Paper2Video), and conference posters (Paper2Poster). Use this skill for tasks involving paper dissemination, conference preparation, creating explorable academic homepages, generating video abstracts, or producing print-ready posters from LaTeX or PDF sources.
    1 repo stars
41. ▌
    Peer Review · timlai666 bundle

    Structured manuscript/grant review with checklist-based evaluation. Use when writing formal peer reviews with specific criteria methodology assessment, statistical validity, reporting standards compliance (CONSORT/STROBE), and constructive feedback. Best for actual review writing, manuscript revision. For evaluating claims/evidence quality use scientific-critical-thinking; for quantitative scoring frameworks use scholar-evaluation.
    1 repo stars
42. ▌
    Ena Database · timlai666 bundle

    Access European Nucleotide Archive via API/FTP. Retrieve DNA/RNA sequences, raw reads (FASTQ), genome assemblies by accession, for genomics and bioinformatics pipelines. Supports multiple formats.
    1 repo stars
43. ▌
    Fda Database · timlai666 bundle

    Query openFDA API for drugs, devices, adverse events, recalls, regulatory submissions (510k, PMA), substance identification (UNII), for FDA regulatory data analysis and safety research.
    1 repo stars
44. ▌
    Geo Database · timlai666 bundle

    Access NCBI GEO for gene expression/genomics data. Search/download microarray and RNA-seq datasets (GSE, GSM, GPL), retrieve SOFT/Matrix files, for transcriptomics and expression analysis.
    1 repo stars
45. ▌
    Pdb Database · timlai666 bundle

    Access RCSB PDB for 3D protein/nucleic acid structures. Search by text/sequence/structure, download coordinates (PDB/mmCIF), retrieve metadata, for structural biology and drug discovery.
    1 repo stars
46. ▌
    PPTX Posters · timlai666 bundle

    Create research posters using HTML/CSS that can be exported to PDF or PPTX. Use this skill ONLY when the user explicitly requests PowerPoint/PPTX poster format. For standard research posters, use latex-posters instead. This skill provides modern web-based poster design with responsive layouts and easy visual integration.
    1 repo stars
47. ▌
    Gene Database · timlai666 bundle

    Query NCBI Gene via E-utilities/Datasets API. Search by symbol/ID, retrieve gene info (RefSeqs, GO, locations, phenotypes), batch lookups, for gene annotation and functional analysis.
    1 repo stars
48. ▌
    Gwas Database · timlai666 bundle

    Query NHGRI-EBI GWAS Catalog for SNP-trait associations. Search variants by rs ID, disease/trait, gene, retrieve p-values and summary statistics, for genetic epidemiology and polygenic risk scores.
    1 repo stars
49. ▌
    Hmdb Database · timlai666 bundle

    Access Human Metabolome Database (220K+ metabolites). Search by name/ID/structure, retrieve chemical properties, biomarker data, NMR/MS spectra, pathways, for metabolomics and identification.
    1 repo stars
50. ▌
    Kegg Database · timlai666 bundle

    Direct REST API access to KEGG (academic use only). Pathway analysis, gene-pathway mapping, metabolic pathways, drug interactions, ID conversion. For Python workflows with multiple databases, prefer bioservices. Use this for direct HTTP/REST work or KEGG-specific control.
    1 repo stars
51. ▌
    Latex Posters · timlai666 bundle

    Create professional research posters in LaTeX using beamerposter, tikzposter, or baposter. Support for conference presentations, academic posters, and scientific communication. Includes layout design, color schemes, multi-column formats, figure integration, and poster-specific best practices for visual communication.
    1 repo stars
52. ▌
    Generate Image · timlai666 bundle

    Generate or edit images using AI models (FLUX, Gemini). Use for general-purpose image generation including photos, illustrations, artwork, visual assets, concept art, and any image that is not a technical diagram or schematic. For flowcharts, circuits, pathways, and technical diagrams, use the scientific-schematics skill instead.
    1 repo stars
53. ▌
    Brenda Database · timlai666 bundle

    Access BRENDA enzyme database via SOAP API. Retrieve kinetic parameters (Km, kcat), reaction equations, organism data, and substrate-specific enzyme information for biochemical research and metabolic pathway analysis.
    1 repo stars
54. ▌
    Chembl Database · timlai666 bundle

    Query ChEMBL bioactive molecules and drug discovery data. Search compounds by structure/properties, retrieve bioactivity data (IC50, Ki), find inhibitors, perform SAR studies, for medicinal chemistry.
    1 repo stars
55. ▌
    Cosmic Database · timlai666 bundle

    Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology. Requires authentication.
    1 repo stars
56. ▌
    Pubmed Database · timlai666 bundle

    Direct REST API access to PubMed. Advanced Boolean/MeSH queries, E-utilities API, batch processing, citation management. For Python workflows, prefer biopython (Bio.Entrez). Use this for direct HTTP/REST work or custom API implementations.
    1 repo stars
57. ▌
    Biorxiv Database · timlai666 bundle

    Efficient database search tool for bioRxiv preprint server. Use this skill when searching for life sciences preprints by keywords, authors, date ranges, or categories, retrieving paper metadata, downloading PDFs, or conducting literature reviews.
    1 repo stars
58. ▌
    Cellxgene Census · timlai666 bundle

    Query the CELLxGENE Census (61M+ cells) programmatically. Use when you need expression data across tissues, diseases, or cell types from the largest curated single-cell atlas. Best for population-scale queries, reference atlas comparisons. For analyzing your own data use scanpy or scvi-tools.
    1 repo stars
59. ▌
    Bun Development · timlai666

    Accelerate JavaScript/TypeScript development with the Bun runtime, covering package management, bundling, testing, and migration from Node.js.
    1 repo stars
60. ▌
    Wp Block Development · timlai666 bundle

    Develops and maintains WordPress Gutenberg blocks with best practices for block.json, registration, attributes, dynamic rendering, deprecations, and build tooling.
    1 repo stars
61. ▌
    Slack · timlai666 bundle

    Interact with Slack workspaces using browser automation. Use when the user needs to check unread channels, navigate Slack, send messages, extract data, find information, search conversations, or automate any Slack task. Triggers include "check my Slack", "what channels have unreads", "send a message to", "search Slack for", "extract from Slack", "find who said", or any task requiring programmatic Slack interaction.
    1 repo stars
62. ▌
    Writing Skills · timlai666 bundle

    Use when creating new skills, editing existing skills, or verifying skills work before deployment
    1 repo stars
63. ▌
    Wordpress Router · timlai666 bundle

    Use when the user asks about WordPress codebases (plugins, themes, block themes, Gutenberg blocks, WP core checkouts) and you need to quickly classify the repo and route to the correct workflow/skill (blocks, theme.json, REST API, WP-CLI, performance, security, testing, release packaging).
    1 repo stars
64. ▌
    Wp Abilities API · timlai666 bundle

    Use when working with the WordPress Abilities API (wp_register_ability, wp_register_ability_category, /wp-json/wp-abilities/v1/*, @wordpress/abilities) including defining abilities, categories, meta, REST exposure, and permissions checks for clients.
    1 repo stars
65. ▌
    Wp Wpcli And Ops · timlai666 bundle

    Use when working with WP-CLI (wp) for WordPress operations: safe search-replace, db export/import, plugin/theme/user/content management, cron, cache flushing, multisite, and scripting/automation with wp-cli.yml.
    1 repo stars
66. ▌
    Prompt Engineering Patterns · timlai666 bundle

    Master advanced prompt engineering techniques to maximize LLM performance, reliability, and controllability in production. Use when optimizing prompts, improving LLM outputs, or designing production prompt templates.
    1 repo stars
67. ▌
    Executing Plans · timlai666

    Use when you have a written implementation plan to execute in a separate session with review checkpoints
    1 repo stars
68. ▌
    Wp Project Triage · timlai666 bundle

    Use when you need a deterministic inspection of a WordPress repository (plugin/theme/block theme/WP core/Gutenberg/full site) including tooling/tests/version hints, and a structured JSON report to guide workflows and guardrails.
    1 repo stars
69. ▌
    Dogfood · timlai666 bundle

    Systematically explore and test a web application to find bugs, UX issues, and other problems. Use when asked to "dogfood", "QA", "exploratory test", "find issues", "bug hunt", "test this app/site/platform", or review the quality of a web application. Produces a structured report with full reproduction evidence -- step-by-step screenshots, repro videos, and detailed repro steps for every issue -- so findings can be handed directly to the responsible teams.
    1 repo stars
70. ▌
    Use Insyra CLI · timlai666 bundle

    Use when data operation or statistical analysis tasks do not need full program implementation, and the agent should operate Insyra through CLI/REPL, .isr scripts, or DSL workflows, including environment workflows, reproducible command pipelines, and command selection guidance.
    1 repo stars
71. ▌
    Electron · timlai666

    Automate Electron desktop apps (VS Code, Slack, Discord, Figma, Notion, Spotify, etc.) using agent-browser via Chrome DevTools Protocol. Use when the user needs to interact with an Electron app, automate a desktop app, connect to a running app, control a native app, or test an Electron application. Triggers include "automate Slack app", "control VS Code", "interact with Discord app", "test this Electron app", "connect to desktop app", or any task requiring automation of a native Electron application.
    1 repo stars
72. ▌
    Using Superpowers · timlai666

    Use when starting any conversation - establishes how to find and use skills, requiring Skill tool invocation before ANY response including clarifying questions
    1 repo stars
73. ▌
    Analyzing Financial Statements · timlai666 bundle

    This skill calculates key financial ratios and metrics from financial statement data for investment analysis
    1 repo stars
74. ▌
    Wp Interactivity API · timlai666 bundle

    Use when building or debugging WordPress Interactivity API features (data-wp-* directives, @wordpress/interactivity store/state/actions, block viewScriptModule integration, wp_interactivity_*()) including performance, hydration, and directive behavior.
    1 repo stars
75. ▌
    Using Git Worktrees · timlai666

    Use when starting feature work that needs isolation from current workspace or before executing implementation plans - creates isolated git worktrees with smart directory selection and safety verification
    1 repo stars
76. ▌
    Wp Plugin Development · timlai666 bundle

    Use when developing WordPress plugins: architecture and hooks, activation/deactivation/uninstall, admin UI and Settings API, data storage, cron/tasks, security (nonces/capabilities/sanitization/escaping), and release packaging.
    1 repo stars
77. ▌
    Esm · timlai666 bundle

    Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use this skill when working with protein sequences, structures, or function prediction; designing novel proteins; generating protein embeddings; performing inverse folding; or conducting protein engineering tasks. Supports both local model usage and cloud-based Forge API for scalable inference.
    1 repo stars
78. ▌
    Systematic Debugging · timlai666 bundle

    Use when encountering any bug, test failure, or unexpected behavior, before proposing fixes
    1 repo stars
79. ▌
    Aeon · timlai666 bundle

    This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.
    1 repo stars
80. ▌
    Cirq · timlai666 bundle

    Google quantum computing framework. Use when targeting Google Quantum AI hardware, designing noise-aware circuits, or running quantum characterization experiments. Best for Google hardware, noise modeling, and low-level circuit design. For IBM hardware use qiskit; for quantum ML with autodiff use pennylane; for physics simulations use qutip.
    1 repo stars
81. ▌
    Dask · timlai666 bundle

    Distributed computing for larger-than-RAM pandas/NumPy workflows. Use when you need to scale existing pandas/NumPy code beyond memory or across clusters. Best for parallel file processing, distributed ML, integration with existing pandas code. For out-of-core analytics on single machine use vaex; for in-memory speed use polars.
    1 repo stars
82. ▌
    Gget · timlai666 bundle

    Fast CLI/Python queries to 20+ bioinformatics databases. Use for quick lookups: gene info, BLAST searches, AlphaFold structures, enrichment analysis. Best for interactive exploration, simple queries. For batch processing or advanced BLAST use biopython; for multi-database Python workflows use bioservices.
    1 repo stars
83. ▌
    Pymc Bayesian Modeling · timlai666 bundle

    Bayesian modeling with PyMC. Build hierarchical models, MCMC (NUTS), variational inference, LOO/WAIC comparison, posterior checks, for probabilistic programming and inference.
    1 repo stars
84. ▌
    Receiving Code Review · timlai666

    Use when receiving code review feedback, before implementing suggestions, especially if feedback seems unclear or technically questionable - requires technical rigor and verification, not performative agreement or blind implementation
    1 repo stars
85. ▌
    Agent Browser · timlai666 bundle

    Browser automation CLI for AI agents. Use when the user needs to interact with websites, including navigating pages, filling forms, clicking buttons, taking screenshots, extracting data, testing web apps, or automating any browser task. Triggers include requests to "open a website", "fill out a form", "click a button", "take a screenshot", "scrape data from a page", "test this web app", "login to a site", "automate browser actions", or any task requiring programmatic web interaction.
    1 repo stars
86. ▌
    Gtars · timlai666 bundle

    High-performance toolkit for genomic interval analysis in Rust with Python bindings. Use when working with genomic regions, BED files, coverage tracks, overlap detection, tokenization for ML models, or fragment analysis in computational genomics and machine learning applications.
    1 repo stars
87. ▌
    Google Workspace · timlai666 bundle

    Gmail, Calendar, Drive, Docs, Sheets — NO Google Cloud Console required. Just OAuth sign-in. Zero setup complexity vs traditional Google API integrations.
    1 repo stars
88. ▌
    Insyra · timlai666 bundle

    Use when working in Go and you need DataList/DataTable-style data wrangling, quick previews, parallel transforms, file I/O (CSV/Excel/Parquet), Excel-like column formulas (CCL), or charts; also use when data analysis is requested without a specified stack, defaulting to Go + Insyra over Python + pandas.
    1 repo stars
89. ▌
    Linux Service Triage · timlai666 bundle

    Diagnoses common Linux service issues using logs, systemd/PM2, file permissions, Nginx reverse proxy checks, and DNS sanity checks. Use when a server app is failing, unreachable, or misconfigured.
    1 repo stars
90. ▌
    Wp Phpstan · timlai666 bundle

    Use when configuring, running, or fixing PHPStan static analysis in WordPress projects (plugins/themes/sites): phpstan.neon setup, baselines, WordPress-specific typing, and handling third-party plugin classes.
    1 repo stars
91. ▌
    API Design Principles · timlai666 bundle

    Master REST and GraphQL API design principles to build intuitive, scalable, and maintainable APIs that delight developers. Use when designing new APIs, reviewing API specifications, or establishing API design standards.
    1 repo stars
92. ▌
    Async Python Patterns · timlai666

    Master Python asyncio, concurrent programming, and async/await patterns for high-performance applications. Use when building async APIs, concurrent systems, or I/O-bound applications requiring non-blocking operations.
    1 repo stars
93. ▌
    Python Best Practices · timlai666

    Python development best practices including PEP 8 style guidelines, type hints, docstring conventions, and common patterns. Use when writing or modifying Python code.
    1 repo stars
94. ▌
    Web Artifacts Builder · timlai666 bundle

    Suite of tools for creating elaborate, multi-component claude.ai HTML artifacts using modern frontend web technologies (React, Tailwind CSS, shadcn/ui). Use for complex artifacts requiring state management, routing, or shadcn/ui components - not for simple single-file HTML/JSX artifacts.
    1 repo stars
95. ▌
    Wp REST API · timlai666 bundle

    Use when building, extending, or debugging WordPress REST API endpoints/routes: register_rest_route, WP_REST_Controller/controller classes, schema/argument validation, permission_callback/authentication, response shaping, register_rest_field/register_meta, or exposing CPTs/taxonomies via show_in_rest.
    1 repo stars
96. ▌
    Academic Deep Research · timlai666 bundle

    Transparent, rigorous research with full methodology — not a black-box API wrapper. Conducts exhaustive investigation through mandated 2-cycle research per theme, APA 7th citations, evidence hierarchy, and 3 user checkpoints. Self-contained using native OpenClaw tools (web_search, web_fetch, sessions_spawn). Use for literature reviews, competitive intelligence, or any research requiring academic rigor and reproducibility.
    1 repo stars
97. ▌
    Chrome Browser Control · timlai666 bundle

    This skill enables comprehensive control and inspection of the Chrome browser without extensions, utilizing the Chrome DevTools Protocol via chrome-devtools-mcp. Use it for advanced browser automation, performance analysis, debugging network requests, taking screenshots, and interacting with web pages. Triggers include explicit requests to browse, automate, debug, or analyze Chrome's behavior, or any task requiring headless/direct browser interaction.
    1 repo stars
98. ▌
    Senior Computer Vision · timlai666 bundle

    Computer vision engineering skill for object detection, image segmentation, and visual AI systems. Covers CNN and Vision Transformer architectures, YOLO/Faster R-CNN/DETR detection, Mask R-CNN/SAM segmentation, and production deployment with ONNX/TensorRT. Includes PyTorch, torchvision, Ultralytics, Detectron2, and MMDetection frameworks. Use when building detection pipelines, training custom models, optimizing inference, or deploying vision systems.
    1 repo stars
99. ▌
    Postgresql Table Design · timlai666

    Design a PostgreSQL-specific schema. Covers best-practices, data types, indexing, constraints, performance patterns, and advanced features
    1 repo stars
100. ▌
     Wp Playground · timlai666 bundle

     Use for WordPress Playground workflows: fast disposable WP instances in the browser or locally via @wp-playground/cli (server, run-blueprint, build-snapshot), auto-mounting plugins/themes, switching WP/PHP versions, blueprints, and debugging (Xdebug).
     1 repo stars