Product & Planning

fridrichmethod Bundle

Local Scanpy pipeline for single-cell RNA-seq QC, clustering, marker discovery, and optional two-group differential expression from raw-count .h5ad.

fridrichmethod Bundle

Stratifies patients into multi-omics subtypes by building one patient-by-patient similarity network per omic, fusing them with SNF's cross-network diffusion, and spectral-clustering the fused graph - then defending the clusters with stability, survival separation, and replication. Covers why spectral clustering always returns the requested cluster count so a subtype is a claim not a discovery, why the eigengap is a graph property not a biological truth, why fusion is not automatically better than the best single omic, why SNF needs complete data while NEMO handles mosaic cohorts, and the SNFtool API gotchas (dist2 returns squared distance, affinityMatrix width is sigma, spectralClustering K is the cluster count). Use when discovering patient subtypes from multiple omics, choosing a cluster number, validating subtypes, or handling partial multi-omic data. For feature-space factors see mofa-integration; for supervised signatures see mixomics-analysis; for survival see clinical-biostatistics/survival-analysis.

fridrichmethod Bundle

Infer or annotate TCR antigen specificity by unsupervised clustering (TCRdist/tcrdist3, GLIPH2, clusTCR, GIANA) and database lookup (VDJdb, IEDB, McPAS-TCR), and rank candidates with supervised predictors (ERGO-II, NetTCR-2.x, pMTnet) under explicit caveats. Encodes the central truth that general TCR-epitope prediction for UNSEEN epitopes essentially does not work (collapses to near-random; IMMREP22, Grazioli 2022) because labeled data is dominated by a few immunodominant epitopes and there is no true negative set — so clustering for discovery is the honest task and de-novo binding needs wet-lab validation. Use when annotating TCR specificity or grouping a repertoire. Epitope/MHC context lives in mhc-binding-prediction.

fridrichmethod Bundle

End-to-end bulk time-course analysis from an expression matrix to temporal gene modules and per-cluster pathway enrichment. Orchestrates temporal DE (limma splines or DESeq2 LRT), Mfuzz/tslearn soft clustering of expression-profile shapes, GAM trajectory fitting, per-cluster GO enrichment against a temporal-gene background, and an OPTIONAL circadian rhythm-detection branch (MetaCycle/CosinorPy) that runs only when the design covers >=2 full cycles with >=6-8 evenly spaced samples per cycle. Use when analyzing a bulk time-series expression experiment from any omics platform and deciding limma-splines vs DESeq2-LRT for temporal DE, soft vs hard clustering, whether the sampling design even licenses rhythm detection, and which background to use for enrichment. Not for single-cell pseudotime (see temporal-genomics/trajectory-modeling for the bulk-vs-pseudotime boundary) or unknown-period discovery (see temporal-genomics/periodicity-detection).

fridrichmethod Bundle

Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero. Use when linking distal enhancers to target genes, choosing between contact-aware (ABC, ENCODE-rE2G), accessibility-only (Cicero), and orthogonal (HiChIP H3K27ac, EpiMap) approaches, validating predictions against CRISPRi-FlowFISH gold-standard, or building cell-type-specific regulatory maps for fine-mapping or therapeutic target discovery.

intense-visions Bundle

Microservices: Service Discovery

nvidia-nemo-rl Bundle

Autonomous NeMo-RL research agent workflow for directed hypothesis testing and open-ended discovery. Guides agents through the full experiment lifecycle: understanding recipes and environments, wiring RL or NeMo-gym runs, launching reproducible baselines and iterations, analyzing results, preserving human oversight, and using git plus TSV logs as the research ledger. Do NOT use for: bug fixes, code review, documentation, refactoring, dependency updates, or single-file changes.

ericgrill Skill

Automate Eventbrite event management, attendee tracking, organization discovery, and category browsing through natural language commands

ericgrill Skill

Automate SurveyMonkey survey creation, response collection, collector management, and survey discovery through natural language commands

ngxtm-devkit Bundle

Service discovery, configuration, circuit breakers, load balancing, and API gateway.

composio-community Skill

One CLI for all of Google Workspace — Drive, Gmail, Calendar, Sheets, Docs, Chat, Admin, and more. Dynamically built from Google's Discovery Service. Use when an agent needs broad Google Workspace access with 100+ built-in agent skills.

square-lupus579 Bundle

SEO strategy planning: competitor analysis, keyword strategy, content calendar, and implementation roadmap. Use when user says "SEO plan", "SEO strategy", "content calendar", or "SEO roadmap".

hernamesbarbara Skill

Strip assistant meta-noise and decision-log chatter from project management assets stored either as local documents or GitHub issues. Produces clean, confident, implementation-ready writing that reads as if written by a domain expert. Invocable via slash command or implicit discovery by an AI coding agent automatically. Use this to scrub AI-drafted specs, issues, notes, plans, or memos after interactive chat sessions with AI coding assistants.

boisenoise Bundle

When the user wants to generate, iterate, or scale ad creative — headlines, descriptions, primary text, or full ad variations — for any paid advertising platform. Also use when the user mentions 'ad copy variations,' 'ad creative,' 'generate headlines,' 'RSA headlines,' 'bulk ad copy,' 'ad iterations,' 'creative testing,' 'write me some ads,' 'Facebook ad copy,' 'Google ad headlines,' 'LinkedIn ad text,' 'static ads,' 'ad templates,' 'iMessage ad,' 'chat reveal ad,' 'ChatGPT ad,' 'Apple Notes ad,' 'AirDrop ad,' 'creative strategy,' 'creative roadmap,' 'creative retro,' 'hook writing,' 'creative review page,' 'present ad creative for approval,' 'motion video ad,' 'faceless video ad,' 'UGC ad,' 'greenscreen ad,' 'TikTok/Reels ad format,' 'which ad format to make,' 'Meta ad format tier list,' or 'creative format taxonomy.' Use this whenever someone needs to produce ad copy at scale or iterate on existing ads. For campaign strategy and targeting, see ads. For landing page copy, see copywriting.

boisenoise Bundle

This skill should be used when agent work needs file-backed context: durable scratchpads, tool-output offloading, just-in-time discovery, cross-agent handoff files, filesystem memory, or cleanup policies for context stored outside the prompt.

awarexone Skill

AI-powered tools for Web3 bug bounty automation. Use when you want to automate recon, run autonomous audits, or use AI agents for vulnerability discovery.

awarexone Skill

External research synthesis from Trail of Bits, SlowMist, ConsenSys, Immunefi, and Cyfrin. Use this for advanced audit methodology, Echidna/Medusa fuzzing setup, Slither custom detector writing, attack pattern deep dives, or the 4-phase learning roadmap.

sones3 Skill

Turn the current conversation context into a PRD and submit it as a GitHub issue. Use when user wants to create a PRD from the current context.

vikynofebriputra-creator Bundle

Use to design and implement product UI from PRD, product goals, user flows, or existing app context. Use when the user asks to build or improve a UI, frontend screen, landing page, dashboard, component set, design-system-based interface, Figma-style brief plus implementation, brand-inspired UI, responsive layout, accessibility pass, or visual polish.

vikynofebriputra-creator Bundle

Use to write or refine a PRD after product demand is reasonably understood and before acceptance criteria, design handoff, engineering breakdown, or implementation planning. Use when the user asks for a PRD, product requirements document, scope definition, engineering-ready requirements, requirements handoff, goals and success metrics, functional requirements, non-functional needs, dependencies, risks, milestones, or open questions.

vikynofebriputra-creator Bundle

Use to turn a PRD section, user story, feature slice, or behavior description into product test scenarios and pass/fail conditions. Use when the user asks for product testing, acceptance criteria, Given/When/Then scenarios, QA-ready scenarios, pass/fail checks, edge cases, error states, non-functional acceptance checks, or story-level verification.

wendylabsinc Skill

Linear issue tracking and project management through the CLI or GraphQL API. Use when developers mention: (1) Linear issues or tickets, (2) issue tracking or task management, (3) WDY team issues, (4) closing, updating, or triaging tickets, (5) linking PRs to issues, (6) issue states (triage, backlog, started, completed).

26zl Bundle

Discover and inventory shadow API endpoints that operate outside documented specifications using traffic analysis, code scanning, and API discovery platforms.

26zl Bundle

Manages the end-to-end cyber threat intelligence lifecycle from planning and direction through collection, processing, analysis, dissemination, and feedback to ensure intelligence products meet stakeholder requirements and continuously improve. Use when establishing or maturing a CTI program, defining intelligence requirements with business stakeholders, or building feedback loops between intelligence consumers and producers. Activates for requests involving CTI program maturity, intelligence requirements, PIRs, or intelligence lifecycle management.

26zl Bundle

Audit service accounts across enterprise infrastructure to identify orphaned, over-privileged, and non-compliant accounts. This skill covers discovery of service accounts in Active Directory, cloud pl

26zl Bundle

Conducts comprehensive network penetration tests against authorized target environments by performing host discovery, port scanning, service enumeration, vulnerability identification, and controlled exploitation to assess the security posture of network infrastructure. The tester follows PTES methodology from reconnaissance through post-exploitation and reporting. Activates for requests involving network pentest, infrastructure security assessment, internal network testing, or external perimeter testing.

26zl Bundle

Perform coverage-guided fuzzing of compiled binaries using AFL++ (American Fuzzy Lop Plus Plus) to discover memory corruption, crashes, and security vulnerabilities. The tester instruments target binaries with afl-cc/afl-clang-fast, manages input corpora with afl-cmin and afl-tmin, runs parallel fuzzing campaigns with afl-fuzz, and triages crashes using CASR or GDB scripts. Activates for requests involving binary fuzzing, crash discovery, coverage-guided testing, or AFL++ fuzzing campaigns.

26zl Bundle

Implements external attack surface management (EASM) using Shodan, Censys, and ProjectDiscovery tools (subfinder, httpx, nuclei) for asset discovery, subdomain enumeration, service fingerprinting, and exposure scoring. Includes a weighted risk scoring algorithm based on OWASP attack surface analysis methodology and the Relative Attack Surface Quotient (RSQ). Use when building continuous ASM programs or performing external reconnaissance for security assessments.

dojogenesis Skill

Interactive workspace discovery - learn what tools, workflows, agents, and hooks are available

dojogenesis Skill

Senior Project Manager for enterprise software, SaaS, and digital transformation projects. Specializes in portfolio management, quantitative risk analysis, resource optimization, stakeholder alignment, and executive reporting. Uses advanced methodologies including EMV analysis, Monte Carlo simulation, WSJF prioritization, and multi-dimensional health scoring. Use when a user needs help with project plans, project status reports, risk assessments, resource allocation, project roadmaps, milestone tracking, team capacity planning, portfolio health reviews, program management, or executive-level project reporting — especially for enterprise-scale initiatives with multiple workstreams, complex dependencies, or multi-million dollar budgets.

dojogenesis Skill

Use when validating product opportunities, mapping assumptions, planning discovery sprints, or testing problem-solution fit before committing delivery resources.

dojogenesis Skill

Strategic product leadership toolkit for Head of Product covering OKR cascade generation, quarterly planning, competitive landscape analysis, product vision documents, and team scaling proposals. Use when creating quarterly OKR documents, defining product goals or KPIs, building product roadmaps, running competitive analysis, drafting team structure or hiring plans, aligning product strategy across engineering and design, or generating cascaded goal hierarchies from company to team level.

dojogenesis Skill

Analyzes competitor products and companies by synthesizing data from pricing pages, app store reviews, job postings, SEO signals, and social media into structured competitive intelligence. Produces feature comparison matrices scored across 12 dimensions, SWOT analyses, positioning maps, UX audits, pricing model breakdowns, action item roadmaps, and stakeholder presentation templates. Use when conducting competitor analysis, comparing products against competitors, researching the competitive landscape, building battle cards for sales, preparing for a product strategy or roadmap session, responding to a competitor's new feature or pricing change, or performing a quarterly competitive review.

dojogenesis Skill

Use when preparing roadmap narratives, release notes, changelogs, or stakeholder updates tailored for executives, engineering teams, and customers.

hk-hub Skill

Turn a PRD into a multi-phase implementation plan using tracer-bullet vertical slices, saved as a local Markdown file in ./plans/. Use when user wants to break down a PRD, create an implementation plan, plan phases from a PRD, or mentions "tracer bullets".

hk-hub Skill

Create a PRD through user interview, codebase exploration, and module design, then submit as a GitHub issue. Use when user wants to write a PRD, create a product requirements document, or plan a new feature.