Research & Search

gabrielmoreira Skill

Builds prioritized manuscript revision plans for major or minor revisions by separating comments that require experiments, analyses, clarification, restructuring, or wording changes.

gabrielmoreira Skill

Use when building a sample-level hierarchical clustering dendrogram from a bulk expression matrix and sample annotation table, especially for QC, batch inspection, or sample similarity assessment. Trigger keywords: hierarchical clustering, dendrogram, sample QC, batch inspection, sample similarity. NOT for: differential expression testing, gene clustering heatmaps, single-cell clustering workflows.

gabrielmoreira Skill

Reads a paper figure by figure before re-integrating the full narrative, so the user can identify the core findings quickly and check whether each visual actually supports the authors' main claims. Always separate figure content, figure-linked claim, evidentiary strength, and unsupported interpretation. Never fabricate references, PMIDs, DOIs, figure content, panel labels, result values, or study details that were not actually provided.

gabrielmoreira Skill

Quickly judges whether a biomedical paper is worth deep reading by screening for question fit, design quality, sample adequacy, methodological novelty, and reproducibility value.

gabrielmoreira Skill

Design a structured case-control study framework with explicit source population logic, control selection rules, matching decisions, exposure measurement planning, and bias-control checkpoints.

gabrielmoreira Skill

Generates complete network toxicology + molecular docking research designs from a user-provided toxicant and disease/phenotype. Always use this skill when users want to investigate how an environmental toxicant, endocrine disruptor, heavy metal, food contaminant, pharmaceutical residue, or consumer product chemical may contribute to a disease through shared molecular targets, hub genes, pathways, and docking evidence. Trigger for:"network toxicology study", "toxicology mechanism paper", "target prediction + PPI + docking", "environmental pollutant and disease mechanism", "hub genes and docking for toxicant", "Lite/Standard/Advanced toxicology plan", "CTD + SwissTargetPrediction + GeneCards + STRING", "CB-Dock2 docking study", "triclosan/BPA/cadmium/PFAS + disease". Also triggers for Chinese phrasings:"网络毒理学研究设计"、"毒物机制论文"、"靶点预测+PPI+对接"、"环境污染物与疾病机制". Trigger even for casual phrasings like "I want to study how chemical X affects disease Y" or "help me design a toxicology paper". Always output four workload confi

gabrielmoreira Skill

Identify federal, provincial, territorial, modal, product, workplace, and activity jurisdiction for Canadian logistics research.

gabrielmoreira Skill

Formulate statistical research problems with formal notation, target parameters, assumptions, hypotheses, evaluation criteria, and theory targets.

gabrielmoreira Skill

Writes Specific Aims pages for grant applications. Use when drafting or revising the Specific Aims page (NIH R01/R21/R03), NSF Project Summary, or equivalent for any major funding agency. Also triggers on "write my specific aims", "help me draft specific aims for NIH", "what should a specific aims page include", "NSF project summary", "write my grant aims", or "how do I structure an R01".

gabrielmoreira Skill

Organizes biomedical figures, analyses, and result blocks into a clear Results section structure with disciplined narrative ordering and evidence-aware presentation.

gabrielmoreira Skill

Use when selecting predictive genes or other molecular features from bulk expression matrices for binary case-vs-control classification with elastic net logistic regression, including coefficient path and cross-validation plots. Trigger keywords: elastic net, glmnet, feature selection, binary classification, lambda.min, lambda.1se. NOT for: survival/Cox modeling, multiclass outcomes, single-cell data, or non-expression tables.

gabrielmoreira Skill

Assesses whether study results are trustworthy by auditing design integrity, sample structure, statistical handling, bias control, validation chain, and claim discipline. It identifies where results are robust, fragile, overfit, under-validated, or overclaimed. Always separate reported findings from reliability judgment. Never fabricate references, PMIDs, DOIs, trial identifiers, study features, or validation claims.

gabrielmoreira Skill

Designs primary aims, secondary aims, and testable hypotheses from broad biomedical research ideas. Use this skill when a user needs to convert a loose study idea into a tighter protocol-framing structure with clear aim hierarchy, hypothesis discipline, and separation between hypothesis-driven and exploratory components. Always keep aims answerable, non-overlapping, and aligned to the intended evidence type and study scope.

gabrielmoreira Skill

Identify federal, state, territorial, modal, product, workplace, and activity jurisdiction for United States logistics research.

gabrielmoreira Skill

Writes the full Introduction section of a biomedical manuscript based on an approved or sufficiently clear study logic, while preserving evidence boundaries and introduction discipline.

gabrielmoreira Skill

Checks whether manuscript references are accurately matched to claims, appropriately scoped, and not overextended, misquoted, or second-hand cited.

gabrielmoreira Skill

Use this skill to compute ESTIMATE immune-related microenvironment scores from a bulk expression matrix, generate an ESTIMATE score heatmap, and optionally generate group-wise ESTIMATE score boxplots plus significance tables when a sample group file is supplied. Trigger keywords: ESTIMATE, immune score, stromal score, tumor microenvironment score. NOT for: immune cell deconvolution, single-cell analysis, differential expression, clinical diagnosis.

gabrielmoreira Skill

Scans the biomarker landscape of a disease area by biomarker type, clinical/research use case, evidence layer, validation status, and maturity level. Use this skill when a user wants a field-level biomarker evidence map rather than a generic literature summary. Always separate exploratory biomarkers from externally validated or clinically embedded biomarkers, and never imply clinical maturity without explicit evidence support.

gabrielmoreira Skill

Clarifies a vague clinical or biomedical research idea into a structured, bounded, searchable, researchable, and testable question. Always use this skill whenever a user has an early-stage clinical or research thought, an over-broad topic, an ill-defined evidence question, or an unclear problem statement that must be translated into a question framing suitable for literature retrieval, evidence synthesis, gap analysis, study design, or downstream protocol planning. Never jump straight to answering the substantive medical question unless the user explicitly asks for that. Focus first on question framing, boundary setting, and downstream-ready formulation.

gabrielmoreira Skill

Identifies real, evidence-audited, topic-specific research gaps in medical research by first retrieving and verifying literature from trusted sources, then mapping the current evidence landscape, rejecting pseudo-gaps, and converting only medium/high-confidence gaps into study-ready research opportunities. Always require real literature retrieval before formal gap claims. Never fabricate references, metadata, or findings.

gabrielmoreira Skill

Designs primary, secondary, and exploratory endpoints for biomedical and clinical research protocols. Always use this skill when a user needs to translate study aims into operational endpoint definitions with event rules, assessment timing, composite logic, interpretability, and protocol-stage auditability. Focus on endpoint precision, feasibility, clinical meaning, ambiguity reduction, and implementation readiness rather than generic study design advice.

gabrielmoreira Skill

Designs internal, external, temporal, and functional validation strategies at the protocol stage for medical research studies.

gabrielmoreira Skill

Prepare Canadian powered industrial equipment safety research briefs for forklifts, lift trucks, conveyors, AGVs, AMRs, and ASRS interfaces.

gabrielmoreira Skill

Converts a biomedical study storyline into a graphical abstract and, when direct image capability is available, generates the graphical abstract directly; otherwise it falls back to prompts, Mermaid flowcharts, or designer-facing briefs.

gabrielmoreira Skill

Optimizes manuscript titles and abstracts for information density, factual accuracy, and submission fit in biomedical research writing.

gabrielmoreira Skill

Use this skill to run GSVA or ssGSEA pathway-level differential analysis from a bulk expression matrix and a sample group file, then generate a heatmap from the saved GSVA result object. Trigger keywords: GSVA, ssGSEA, pathway enrichment, KEGG pathway analysis, MSigDB. NOT for: gene-level differential expression, single-cell analysis, methylation analysis, clinical diagnosis.

gabrielmoreira Skill

Tracks the latest preprints and emerging research topics related to your topic across bioRxiv, medRxiv, and arXiv. Use when a user wants to discover what is being published right now before it reaches journals, monitor competitor directions, spot new methodology trends, or get an early-warning scan of a research area. Triggers on phrases like "what's new in X", "latest preprints on Y", "emerging topics in Z", "monitor bioRxiv for", or "what are people working on in this field".

gabrielmoreira Skill

Designs a translational blueprint for moving a biomedical finding toward diagnosis, prognosis, treatment response prediction, patient stratification, or therapeutic development, with explicit translational milestones, validation thresholds, and feasibility-sensitive route framing.

gabrielmoreira Skill

Clinical Research Bias Assessment - Case-Control Study (NOS) v2.3.0. Use when you need to assess the bias of a case-control study using the Newcastle-Ottawa Scale (NOS) criteria, or when evaluating the quality of a medical paper.

gabrielmoreira Skill

Prepare Canadian commercial-vehicle safety research briefs for motor carrier, driver, vehicle, maintenance, and hours-of-service context.

gabrielmoreira Skill

Prepare United States powered industrial truck and powered equipment safety research briefs for logistics operations.

gabrielmoreira Skill

Use when analyzing bulk RNA-seq or microarray expression data to identify differentially expressed genes between two biological groups (case vs control), with volcano plots and heatmap visualization. NOT for:single-cell RNA-seq, methylation analysis, non-expression data.

gabrielmoreira Skill

Extracts concrete unmet clinical needs from guidelines, reviews, real-world studies, and clinical-practice evidence. Use this skill when a user wants to turn broad medical research value into specific clinical pain points such as weak early detection, poor risk stratification, treatment-response heterogeneity, monitoring gaps, diagnostic delay, undertreatment, overtreatment, or implementation failure. Always ground unmet-need claims in retrieved evidence and distinguish true care gaps from generic statements of importance.

gabrielmoreira Skill

CSAR Loop and structured conversation patterns for effective AI dialog -- Clarify, Summarize, Act, Reflect

gabrielmoreira Skill

Prepare United States commercial-vehicle safety research briefs for motor carrier, driver, vehicle, maintenance, and hours-of-service context.

gabrielmoreira Skill

Prepare PHMSA and DOT hazardous-materials research briefs for United States logistics without classifying or certifying hazmat.