Results for “binding-assay”

Use with analysis-agent or task-agent for task-local transaction, isolation, and conflict decisions. Do not use without a transaction decision or as task owner.

Tests API endpoints for mass assignment vulnerabilities by injecting privileged fields (role, isAdmin, balance) into request bodies and verifying if the server binds them without filtering.

Use `analysis-agent` to map acceptance to validation, `task-agent` to add or run bounded tests, and `review-agent` to assess proof coverage. Skip work with no material change or already-fresh complete validation.

Apply least-privilege tool allowlisting, identity binding, and human-in-the-loop controls for agent tool calls.

`analysis-agent`/`task-agent`/`review-agent`: use for recurrence guards on known defects, incidents, or escaped failures; skip speculative risk without a prior failure mechanism.

Co-fold biomolecular complexes with Boltz-2, an open AlphaFold3-style model — predict protein + ligand (SMILES/CCD), protein + nucleic-acid, and multi-chain structures in one pass, with binding-affinity prediction. Use when folding a protein together with a small-molecule ligand, predicting a holo (ligand-bound) complex or its binding affinity, or co-folding protein–DNA/RNA assemblies. For protein-only or protein–protein folding without ligands prefer alterlab-alphafold; for antibody–antigen complexes prefer alterlab-chai; to dock a ligand into a FIXED receptor structure prefer alterlab-diffdock; to look up an existing structure prefer alterlab-pdb. Part of the AlterLab Academic Skills suite.

Diffusion-based molecular docking. Predict protein-ligand binding poses from PDB/SMILES, confidence scores, virtual screening, for structure-based drug design. Not for affinity prediction.

自动捕获经验并安全进化的技能。触发条件：(1)命令/操作失败时→记ERRORS.md (2)被用户纠正('不对'/'应该是')时→记LEARNINGS.md (3)用户需要不存在的能力时→记FEATURE_REQUESTS.md (4)外部API/工具出错时→记ERRORS.md (5)发现自己知识过时/错误时→记LEARNINGS.md (6)发现更好做法时→记LEARNINGS.md (7)每个任务完成时→回顾过程，有新经验则记LEARNINGS.md。去重原则：如果没有新经验或已有条目已覆盖则跳过不写。每次写入同时在.learnings/CHANGELOG.md追加JSONL日志。经验反复出现≥3次时晋升到AGENTS.md/TOOLS.md/SOUL.md。详见正文。

Predict biomolecular complexes with Chai-1, an open AlphaFold3-style model that folds multi-entity assemblies (proteins, ligands, nucleic acids) from a single typed FASTA — strong on antibody–antigen and protein–ligand complexes, with optional MSA and restraint inputs. Use when predicting an antibody–antigen complex, folding a mixed protein/ligand/nucleic-acid assembly described in one FASTA, or generating a complex with experimental restraints. For binding-affinity prediction or a ligand-focused co-fold prefer alterlab-boltz; for protein-only or protein–protein folding prefer alterlab-alphafold; to dock into a fixed receptor prefer alterlab-diffdock. Part of the AlterLab Academic Skills suite.

AI Manipulation Defense System with self-learning prompt injection detection and adaptive mitigation