Results for “size-factor”

Run differential gene expression analysis on bulk RNA-seq count matrices with PyDESeq2, the Python port of DESeq2 — size-factor normalization, dispersion estimation, Wald tests, FDR (Benjamini-Hochberg) correction, and volcano/MA plots. Use when identifying differentially expressed genes between conditions from raw bulk RNA-seq counts. Part of the AlterLab Academic Skills suite.

Create size guides with measurements and fit advice. TRIGGERS - Use when user needs help with size-guide related tasks.

Decompose an unknown quantity into 3-5 estimable factors and produce a defensible order-of-magnitude answer without needing precise data. Load when the user needs to size something without data — market size, resource requirements, effort estimates, user numbers, costs — or when a decision is blocked by "we don't know the numbers". Also triggers on "ballpark this", "rough estimate", "how big is this market", "how long would this take", "how many users", or when deep-thinking diagnoses a sizing/estimation frame. The goal is not precision — it is a defensible answer that enables a decision to be made. Based on Enrico Fermi's estimation method.

Mede o tamanho estrutural da feature ativa lendo requirements, duvidas, plan e tasks do ciclo forward, e gera size.json mais size.md com T-shirt sizing deterministico baseado em tasks e ajuste de risco. Use quando o usuario digitar "/reversa-pricing-size", "reversa-pricing-size", "dimensionar feature" ou "calcular tamanho da feature". Roda depois de `/reversa-to-do` e antes de `/reversa-pricing-estimate`.

Creates size charts with measurement conversions, fit recommendations, and international sizing standards

Create size guides with measurements and fit advice. TRIGGERS - Use when user needs help with size-guide related tasks.

Safe refactor planning for Nick's codebases. Use when planning large refactors, reducing blast radius, sequencing cleanup work, or deciding how to improve messy code without breaking product velocity.

Improve code structure and readability without changing external behavior through surgical refactoring techniques.

Risk managers should SIZE trades, not BLOCK them. Trigger when: (1) capital manager blocks trades, (2) risk manager rejects orders, (3) trades fail due to 'exceeds limit', (4) components don't work in harmony.

Improves structure without behavior changes, using tests and focused slices; not for features unless behavior change is explicit.

Calculate sample sizes, minimum detectable effects, and power curves for study planning using closed-form formulas or Monte Carlo simulation.

Surgical code refactoring to improve maintainability without changing behavior. Covers extracting functions, renaming variables, breaking down god functions, improving type safety, eliminating code smells, and applying design patterns. Less drastic than repo-rebuilder; use for gradual improvements.

Plan and execute large refactor or rewrite efforts efficiently with parallel multi-agent analysis and implementation.

Apply Fitts's Law to size and position interactive targets for fast, accurate interaction.

Refactors Swift code toward declarative functional programming with immutability, value types, pure functions, transformations, and closure-based APIs.

Calculate risk-based position sizes for long stock trades using fixed fractional, ATR-based, or Kelly Criterion methods with portfolio constraints.

Apply named refactoring transformations to improve code structure without changing behavior, guided by code smells and safe transformation sequences.

Refactor SwiftUI views toward small, explicit, stable view types with MV data flow, dedicated subviews, and correct Observation usage.

MaxFuse parameter tuning when protein panel size changes (26 → 59+ markers)

Splits, merges, moves, or deletes code while preserving behavior, tests, contracts, and boundaries, with characterization evidence and reversible steps.

Surgical code refactoring to improve maintainability without changing behavior. Covers extracting functions, renaming variables, breaking down god functions, improving type safety, eliminating code smells, and applying design patterns. Less drastic than repo-rebuilder; use for gradual improvements.

Designs A/B tests with sample size calculation, statistical significance testing, and result interpretation

Provides a production-proven oversized macOS-style cursor technique for launch videos, covering size, entry, tip-targeting, click animation, and exit laws to carry the viewer's eye.

Use when restructuring code for maintainability while preserving external behavior.

Resize a product photo to Shopify's recommended 2048×2048px square format, sharpen, and convert to WebP for fast storefront load times.

CEO/founder-mode plan review. Rethink the problem, find the 10-star product, challenge premises, expand scope when it creates a better product. Four modes: SCOPE EXPANSION (dream big), SELECTIVE EXPANSION (hold scope + cherry-pick expansions), HOLD SCOPE (maximum rigor), SCOPE REDUCTION (strip to essentials). Use when asked to "think bigger", "expand scope", "strategy review", "rethink this", or "is this ambitious enough". Proactively suggest when the user is questioning scope or ambition of a plan, or when the plan feels like it could be thinking bigger. (gstack)

Creates a dramatic 'giant product' visual by compositing a product image into a scene where it appears building-sized next to a person, with an optional animation step.

Creates long-form magazine-style articles with hero sections, serif headings, styled quotes, code blocks, and call-to-action cards, suitable for Substack, Medium, or blogs.

Use when code is hard to read, has duplication, is too complex, has grown beyond 300 lines, or needs restructuring without changing behavior. For extracting functions, simplifying nested logic, removing dead code, improving naming, splitting large files, and applying clean code principles. Activate when user says "clean this up", "this is messy", "simplify", "extract", or "improve readability".

Modernizes legacy scripts (bash, Node, Python) by replacing deprecated APIs, adding error handling, converting callbacks to async/await, and improving maintainability. Turns brittle one-off scripts into reliable, documented tools.

Build lean, opinionated products using the 37signals philosophy from Getting Real, Rework, and Shape Up. Use when the user mentions "Getting Real", "Rework", "Shape Up", "37signals", "Basecamp method", "six-week cycles", "fixed time variable scope", "appetite vs estimates", "betting table", "breadboarding", "fat marker sketch", "build less", "underdo the competition", or "opinionated software". Also trigger when cutting scope to ship faster, running small teams, avoiding long-term roadmaps, or eliminating meetings. Covers shaping, betting, building, and the art of saying no. For MVP validation, see lean-startup. For design sprints, see design-sprint.

Provides a general step-by-step procedure for handling requests related to end, size, and fs, with placeholders for specifics.

Refactors a class toward the Single Responsibility Principle by identifying responsibilities, grouping cohesive behavior, and extracting focused classes.

Type Scale

Rice