Results for “sui”

Applies medicinal-chemistry filters with the medchem library — drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, and molecular complexity metrics for compound prioritization and library cleanup. Use when filtering or triaging a compound library, flagging PAINS or reactive groups, or assessing drug-likeness of candidate molecules. Part of the AlterLab Academic Skills suite.

Expo framework for React Native. Managed and bare workflows, Expo Router, EAS Build/Submit/Update, config plugins, and Expo SDK modules. USE WHEN: user mentions "Expo", "expo-router", "EAS Build", "expo-cli", "app.json", "expo-config-plugin", "Expo Go" DO NOT USE FOR: bare React Native without Expo - use `react-native`; Flutter - use `flutter`

MySQL relational database. Covers queries, indexes, and optimization. Use when working with MySQL databases. USE WHEN: user mentions "mysql", "mariadb", asks about "AUTO_INCREMENT", "ON DUPLICATE KEY UPDATE", "GROUP_CONCAT", "mysql specific syntax" DO NOT USE FOR: PostgreSQL - use `postgresql` instead, MongoDB - use `mongodb` instead, Oracle - use `oracle` instead, SQL Server - use `sqlserver` instead

WebRTC peer-to-peer communication. Signaling, ICE/STUN/TURN, media streams, data channels, screen sharing, and SFU integration (mediasoup, LiveKit). USE WHEN: user mentions "WebRTC", "video call", "peer-to-peer", "P2P", "screen sharing", "data channel", "STUN", "TURN", "mediasoup", "LiveKit" DO NOT USE FOR: server-to-client streaming - use `sse`; chat messaging - use `socket-io`

This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.

Composite skill — safely refactor a module end-to-end with sequencing, parallel implementation, post-refactor cleanup, and rationale capture. Chains refactor-plan (phased plan + rollback) → three-man-team (architect/builder/reviewer in parallel) → fix-the-suite post-refactor → adr-write → docs-sync. Use for non-trivial refactors that need both careful sequencing and durable record.

Research Twitter/X profiles, tweets, and trends, then take approved engagement and posting follow-through actions through the AIsa relay. Use when: the user needs Twitter/X research plus likes, follows, unfollows, posting, or post-action follow-through without sharing passwords. Supports relay-based reads, OAuth-approved writes, and media-capable posting flows.

Query the Cancer Dependency Map (DepMap) for cancer cell line gene dependency scores (CRISPR Chronos), drug sensitivity data, and gene effect profiles. Use when identifying cancer-specific genetic vulnerabilities, finding synthetic lethal interactions, checking whether a gene is essential in given cell lines, or validating oncology drug targets. Part of the AlterLab Academic Skills suite.

Nx build system and monorepo tools. Advanced task orchestration, generators, and plugins. Use for complex enterprise monorepos with multiple technologies. USE WHEN: user mentions "Nx", "nx.json", "Nx monorepo", "Nx generators", asks about "Nx workspace", "affected commands", "module boundaries" DO NOT USE FOR: Turborepo (use turborepo skill), simple monorepos (Turborepo is simpler), single-package projects

C# 12 language features including records, pattern matching, nullable reference types, LINQ, async/await, and modern language patterns. USE WHEN: user mentions "C#", "C# records", "pattern matching", "LINQ", "async/await", "nullable reference types", "C# generics", "C# language features" DO NOT USE FOR: TypeScript - use `typescript`, Java - use Java skills, F# or VB.NET specific features

Access the Human Metabolome Database (HMDB, 220K+ metabolites), searching by name, HMDB ID, or structure to retrieve chemical properties, biomarker data, NMR/MS reference spectra, and associated pathways. Use when identifying a human metabolite, looking up its biomarker or disease associations, matching NMR/MS spectra, or running metabolomics annotation. Part of the AlterLab Academic Skills suite.

JVM performance profiling with Java Flight Recorder (JFR), jcmd, and GC analysis. Use for identifying bottlenecks and memory issues. USE WHEN: user mentions "Java profiling", "JFR", "JVM performance", asks about "Java Flight Recorder", "jcmd", "heap dump", "GC tuning", "thread dump", "Java memory leak" DO NOT USE FOR: Node.js/Python profiling - use respective skills instead

Oracle Database specific features. Covers data types, sequences, synonyms, partitioning, and Oracle-specific SQL syntax. Use for Oracle database work. USE WHEN: user mentions "oracle", "oracle database", "sequences", "synonyms", "DUAL", "SYSDATE", "NVL", "DECODE", "Oracle partitioning", "Oracle specifics" DO NOT USE FOR: PostgreSQL - use `postgresql` instead, SQL Server - use `sqlserver` instead, PL/SQL programming - use `plsql` instead

Exploit path traversal and local/remote file inclusion (LFI/RFI) via URL parameters, cookies, and hidden fields using ../ sequences, URL encoding (%2e%2e%2f), double encoding (%252e%252e%255c), Unicode bypasses (..%c0%af), and Windows UNC paths. PHP include/require with $_GET/$_POST/$_COOKIE pattern. Target /etc/passwd, boot.ini, web.config. Tools: DotDotPwn, WFuzz, Burp Suite, ZAP.

Scans a codebase for security vulnerabilities using CodeQL's interprocedural data flow and taint tracking analysis. Triggers on "run codeql", "codeql scan", "codeql analysis", "build codeql database", or "find vulnerabilities with codeql". Supports "run all" (security-and-quality suite) and "important only" (high-precision security findings) scan modes. Also handles creating data extension models and processing CodeQL SARIF output.

Search and retrieve preprints from arXiv via the Atom API by keywords, authors, arXiv IDs, date ranges, or subject categories. Use when finding or fetching papers in physics, mathematics, computer science, quantitative biology, quantitative finance, statistics, electrical engineering, or economics, or resolving an arXiv ID to its metadata and PDF. Part of the AlterLab Academic Skills suite.

Symbolic mathematics in Python with SymPy — solve equations algebraically, perform calculus (derivatives, integrals, limits), manipulate algebraic expressions, work with symbolic matrices, and generate executable code from formulas. Use when exact symbolic results are needed rather than numerical approximations, or for physics, number-theory, and geometry computations involving variables and parameters. Part of the AlterLab Academic Skills suite.

Google Cloud Platform SDK integration. Cloud Functions, Firestore, Cloud Storage, Pub/Sub, BigQuery, and Cloud Run. Node.js and Python client libraries. USE WHEN: user mentions "GCP", "Google Cloud", "Cloud Functions", "Firestore", "Cloud Storage", "Pub/Sub", "BigQuery", "Cloud Run", "Firebase" DO NOT USE FOR: AWS services - use `aws`; Azure services - use `azure`; Firebase Auth - use auth skills

Universal code quality principles applicable to all languages. Covers Clean Code, SOLID, complexity metrics, and quality standards. USE WHEN: user mentions "clean code", "SOLID", "code smells", "refactoring", "complexity", asks about "cyclomatic complexity", "cognitive complexity", "code review", "maintainability" DO NOT USE FOR: language-specific linting - use ESLint/Biome skills, security - use OWASP skills, testing - use testing skills

pytest Python testing framework. Covers fixtures, parametrize, and mocking. Use for Python testing. USE WHEN: user mentions "pytest", "python test", "fixture", asks about "@pytest.fixture", "@pytest.mark.parametrize", "conftest.py", "pytest coverage", "python unit test" DO NOT USE FOR: JavaScript/TypeScript - use `vitest` or `jest`; Java - use `junit`; E2E web tests - use `playwright`; Load testing - use locust

Vite frontend build tool and dev server. Fast HMR and optimized builds. USE WHEN: user mentions "Vite", "vite config", "vite.config", asks about "Vite setup", "Vite dev server", "Vite build", "fast HMR" DO NOT USE FOR: Webpack projects (use webpack skill), Next.js (uses its own bundler), Create React App (uses Webpack), library builds with Rollup only

Access and analyze drug information from the DrugBank database — drug properties, interactions, targets, pathways, chemical structures, and pharmacology data. Use when working with pharmaceutical data, drug discovery research, drug-drug interaction analysis, target identification, chemical similarity searches, ADMET predictions, or any task needing detailed drug and drug-target records from DrugBank. Part of the AlterLab Academic Skills suite.

Run fast one-liner queries to 20+ bioinformatics databases from the gget CLI or Python — gene info (Ensembl), BLAST, AlphaFold structures, Enrichr enrichment, and more. Use for quick interactive lookups of genes, sequences, structures, or pathways — for batch processing or advanced BLAST use biopython, for multi-database Python workflows use bioservices. Part of the AlterLab Academic Skills suite.

Jest testing framework. Covers unit tests, mocking, and snapshots. Use for testing React and Node.js projects. USE WHEN: user mentions "jest", "jest test", "snapshot test", asks about "jest.fn", "jest.mock", "toMatchSnapshot", "React testing" DO NOT USE FOR: E2E tests - use `playwright` or `cypress`; Vite projects - use `vitest` instead; React component testing alone - combine with `testing-library`

Yup schema validation library. Popular with Formik for form validation. Use when building forms with React/Formik or needing schema-based validation. USE WHEN: user mentions "Yup", "Formik validation", asks about "yup schema", "Formik setup", "form validation library" DO NOT USE FOR: Zod projects (use zod skill), NestJS/class-validator (use class-validator skill), new projects (prefer Zod)

gRPC service development. Protocol Buffers (protobuf), service definitions, streaming (unary, server, client, bidirectional), interceptors, and code generation for Node.js, Go, Java, and Python. USE WHEN: user mentions "gRPC", "protobuf", "Protocol Buffers", ".proto", "grpc-js", "tonic", "grpc-java", "service mesh RPC" DO NOT USE FOR: REST APIs - use `rest-api`; GraphQL - use `graphql`; WebSocket - use real-time skills

Serverless computing patterns. AWS Lambda, Azure Functions, GCP Cloud Functions. Deployment frameworks: Serverless Framework, AWS SAM, SST. Cold starts, event sources, and production optimization. USE WHEN: user mentions "serverless", "Lambda", "cloud function", "Azure Functions", "SAM", "SST", "Serverless Framework", "cold start", "FaaS" DO NOT USE FOR: container orchestration - use `kubernetes` or `docker`; always-on servers - use backend framework skills

Node.js performance profiling with V8 CPU profiler, heap analysis, and perf_hooks. Use for identifying bottlenecks and memory leaks. USE WHEN: user mentions "Node.js performance", "profiling", "memory leak", asks about "V8 profiler", "heap snapshot", "CPU profile", "perf_hooks", "event loop lag", "Node.js optimization" DO NOT USE FOR: Java/Python profiling - use respective skills instead

CMake build system for C/C++ projects. Modern CMake (3.20+) with targets, properties, presets (CMakePresets.json), FetchContent, find_package, generator expressions, install rules, vcpkg/Conan integration. USE WHEN: user mentions "CMake", "CMakeLists.txt", "CMakePresets", "find_package", "FetchContent", "target_link_libraries", "vcpkg", "Conan", "C++ build" DO NOT USE FOR: Make, autotools, Bazel, Meson, Visual Studio .vcxproj direct editing

Restructure existing code without changing its behavior, through a test-gated refactoring loop: a named target, a green suite over that target before any edit, a planned sequence of small named refactorings, and the full suite re-run after every step. Use when the user wants to refactor, restructure, clean up, simplify, or improve the design of existing code, or to apply refactoring recommendations from a code-review or architectural-analysis report. This skill changes code; it does not review code (use code-review), assess architecture (use architectural-analysis), or build new behavior test-first (use tdd). Do not use it on code inside an active tdd loop; the refactor step of tdd owns that cleanup. Runs its planned sequence to completion without pausing for review; to review each named refactoring as it lands, use pairing.

Query the NHGRI-EBI GWAS Catalog REST API for SNP-trait associations, retrieving variants by rs ID, disease/trait, or gene along with p-values and summary statistics. Use when investigating genome-wide association study hits, mapping a SNP or rsID to traits, building polygenic risk scores, or doing genetic epidemiology lookups. Part of the AlterLab Academic Skills suite.

Query NCBI Gene via the E-utilities and Datasets APIs, searching by gene symbol or Gene ID and retrieving gene information (RefSeqs, GO terms, genomic locations, associated phenotypes) including batch lookups. Use when resolving gene symbols to IDs, annotating gene lists, or pulling functional and positional gene metadata for downstream analysis. Part of the AlterLab Academic Skills suite.

Read and write genomic alignment and variant files in Python with pysam (htslib bindings) — SAM/BAM/CRAM alignments, VCF/BCF variants, and FASTA/FASTQ sequences, plus region extraction and per-base coverage/pileup. Use when scripting NGS data-processing pipelines that parse, filter, index, or compute coverage over BAM/CRAM/VCF files. Part of the AlterLab Academic Skills suite.

Server-Sent Events for real-time server-to-client streaming. Express, Fastify, FastAPI, Spring WebFlux SSE implementations. Event streams, reconnection, and EventSource API. USE WHEN: user mentions "SSE", "Server-Sent Events", "EventSource", "event stream", "text/event-stream", "live feed", "streaming updates" DO NOT USE FOR: bidirectional communication - use `socket-io`; WebRTC - use `webrtc`; LLM streaming - use AI SDK skills

Electron framework for building cross-platform desktop applications with JavaScript, HTML, and CSS. Covers architecture, IPC, security, packaging, auto-updates, and backend integration patterns. USE WHEN: user mentions "Electron", "desktop app", "cross-platform application", asks about "IPC", "main process", "renderer process", "Electron packaging", "auto-updates", "code signing", "Electron security" DO NOT USE FOR: Tauri applications - use `tauri` skill instead

Test horizontal and vertical authorization bypass via session ID swapping between accounts, IDOR through parameter manipulation (invoice=, user=, menuitem=, EventID=), and special header injection (X-Original-URL, X-Rewrite-URL, X-Forwarded-For, X-Remote-IP, X-Client-IP with 127.0.0.1/localhost/RFC1918 values). Tools: Burp Suite with Autorize/AuthMatrix extensions, OWASP ZAP Access Control Testing add-on.