Clinical Trials

Overview

Search, filter, and download clinical trial records from ClinicalTrials.gov. Analyze trial designs, endpoints, enrollment, sponsors, and results. Automate systematic trial discovery.

Installation

uv pip install requests

Search Trials

import requests

params = {
    "query.term": "diabetes AND metformin AND phase 3",
    "pageSize": 25,
    "format": "json",
    "sort": "LastUpdateDate",
}

resp = requests.get("https://clinicaltrials.gov/api/v2/studies", params=params)
data = resp.json()

for study in data.get("studies", []):
    p = study["protocolSection"]
    nct = p["identificationModule"]["nctId"]
    title = p["identificationModule"]["briefTitle"]
    status = p["statusModule"].get("overallStatus", "Unknown")
    print(f"{nct}: {title[:60]} [{status}]")

Study Details

resp = requests.get("https://clinicaltrials.gov/api/v2/studies/NCT04251195")
study = resp.json()
design = study["protocolSection"]["designModule"]
print(f"Purpose: {design.get('primaryPurpose')}")

Workflow

1. Search trials via ClinicalTrials.gov API v2
2. Filter by condition, intervention, phase, status
3. Download structured trial data (JSON)
4. Extract PICO: Population, Intervention, Comparison, Outcome
5. Analyze trial designs, enrollment, and results