dromlakhani
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- ▌ Icsm Target Mid Normal Testosterone · dromlakhaniAims to correct serum total testosterone to the mid-normal reference range for young men during testosterone therapy. Triggers when a clinician monitors treatment and wonders what testosterone level should I aim for or is the patient's T in the target zone.
- ▌ Ata Ppgl Gi Symptom Management · dromlakhaniManages gastrointestinal symptoms from catecholamine excess in pheochromocytoma and paraganglioma, addressing constipation, paralytic ileus, megacolon, or intestinal pseudo-obstruction/perforation. Triggered by clinician queries about treating GI symptoms in PPGL patients with constipation, abdominal distension, or nausea/vomiting.
- ▌ Ppgl Pregnancy Surgical Timing · dromlakhaniDetermines optimal timing for surgical tumor removal in pregnant PPGL patients to balance maternal and fetal risks. Triggered by PPGL diagnosed in pregnant patient, assessing surgical feasibility during pregnancy, or planning intervention for PPGL in gestation.
- ▌ Ata Postop Pituitary Axis Surveillance · dromlakhaniRecommends retesting all pituitary axes starting at 6 weeks after pituitary surgery and periodically to monitor development or resolution of pituitary deficiencies. Use when managing postoperative pituitary surgery patient; triggers include postoperative pituitary surgery patient needing longitudinal hormone monitoring.
- ▌ Endo Serial Mri Pegvisomant Tumor Size · dromlakhaniThis skill suggests serial MRI imaging to assess tumor size in patients receiving pegvisomant therapy for acromegaly. Use when initiating pegvisomant or during follow‑up to monitor for tumor growth.
- ▌ Endo Against 25ohd Test Under 50 · dromlakhaniThe skill advises against routine 25(OH)D testing in asymptomatic adults younger than 50 years who lack established indications for vitamin D assessment. It is triggered when a clinician considers ordering a 25(OH)D test for preventive screening in this age group.
- ▌ Endo Against Vit D Supp Under 50 · dromlakhaniRecommends against empiric vitamin D supplementation beyond the Dietary Reference Intake (DRI) in adults younger than 50 years. Use when a clinician considers vitamin D supplementation for non‑pregnant adults under 50 without established indications for treatment.
- ▌ Endo Vitd Supplementation Over75 · dromlakhaniSuggests empiric vitamin D supplementation to lower mortality risk in adults aged 75 years and older. Triggered by clinician questions such as “Should I prescribe vitamin D to this elderly patient?” or “Is vitamin D supplementation indicated for patients over 75?”
- ▌ Constipation Defecatory Disorder · dromlakhaniStep-wise management of constipation caused by defecatory disorder (pelvic floor dysfunction, dyssynergia, outlet obstruction) using the WGO cascade framework. Trigger when a patient strains excessively even with soft stools, uses manual manoeuvres to defecate, has difficult defecation with a feeling of blockage, is suspected of having pelvic floor dyssynergia, anorectal dyssynergia, obstructed defecation, or rectocele causing constipation.
- ▌ Genryzon Igf1 Titration · dromlakhaniTitrate Genryzon (somatrogon, weekly long-acting growth hormone) dose in a paediatric GHD patient using serum IGF-1 SDS. Encodes the mandatory 4-days-post-dose sampling rule, the target SDS window, the 15% dose-reduction trigger, and the oral estrogen adjustment. Use when a clinician asks how to titrate somatrogon, when to sample IGF-1 on Genryzon, target IGF-1 SDS on weekly GH, what to do if IGF-1 is too high on somatrogon, IGF-1 rising on Genryzon, how to adjust GH dose in a girl started on oral OCP, or presents a paediatric GHD case on somatrogon with an IGF-1 value to interpret. Grounded in the Pfizer India Product Monograph (Genryzon LPD, 2022 — PfLEET 2022-0081166).
- ▌ Enda Add Antihypertensive Uncontrolled Bp · dromlakhaniThis skill suggests initiating antihypertensive treatment while continuing fludrocortisone when blood pressure remains uncontrolled after fludrocortisone dose reduction. Trigger phrases include "BP remains uncontrolled," "persistent hypertension," or "elevated BP despite fludrocortisone adjustment."
- ▌ Enda Adjust Glucocorticoid Stress Illness · dromlakhaniSuggests adjusting glucocorticoid dose according to severity of illness or magnitude of the stressor in patients with primary adrenal insufficiency. Use when patient with PAI has intercurrent illness, fever, or stress.
- ▌ Enda Alternative Glucocorticoid Emergency · dromlakhaniThis skill suggests using prednisolone as an alternative glucocorticoid when hydrocortisone is unavailable for emergency treatment of adrenal crisis. Dexamethasone is the least-preferred option and should only be administered if no other glucocorticoid is available.
- ▌ Enda Annual Screening Autoimmune Diseases · dromlakhaniSuggests periodic screening for autoimmune diseases known to be more prevalent in PAI patients in whom autoimmune origin of PAI has not been excluded; optimal frequency unknown but can be done annually. Use when determining screening schedule for PAI patient with uncertain autoimmune origin.
- ▌ Malignancy Hypercalcemia Workup · dromlakhaniWork up Malignancy-Associated Hypercalcemia (MAH) — distinguish humoral hypercalcemia of malignancy (HHM, PTHrP-driven), local osteolytic hypercalcemia, 1,25(OH)2D-mediated lymphoma hypercalcemia, ectopic PTH secretion, and multiple myeloma — and pick the right confirmatory tests and therapy direction. Trigger when a clinician asks "is this hypercalcemia from cancer", "PTHrP positive what now", "hypercalcemia in lung cancer / breast cancer / lymphoma / myeloma", "humoral hypercalcemia of malignancy", "MAH workup", or any hypercalcemia case with suppressed PTH and a known or suspected malignancy.
- ▌ Es Cushing Against Treatment No Diagnosis · dromlakhaniThis skill recommends against initiating cortisol-lowering treatment when there is no established diagnosis of Cushing's syndrome. It is triggered when a clinician considers treating suspected CS based only on borderline biochemical abnormalities or nonspecific signs without confirmatory testing; examples include "suspected CS", "borderline UFC", "no confirmed diagnosis", "consider empiric ketoconazole".
- ▌ Pdm Glucose Monitoring T2dm · dromlakhaniSuggests either continuous glucose monitor (CGM) or self-monitoring of blood glucose (SMBG) for pregnant individuals with type 2 diabetes. Triggers include decisions about glucose monitoring methods for pregnant patients with T2DM needing a monitoring strategy.
- ▌ Pdm Metformin Insulin Avoid · dromlakhaniRecommends against routine addition of metformin to insulin for pregnant individuals with type 2 diabetes already on insulin. Triggered when considering adding metformin to an insulin regimen in pregnancy for patients with type 2 diabetes.
- ▌ Es Cgm Contraindication Check · dromlakhaniThis skill checks for contraindications or sources of inaccuracy that may affect continuous glucose monitoring (CGM) reliability in hospitalized adults. It is triggered when clinicians ask, “Are there factors that could make CGM unreliable?” or when assessing for skin infection, hypoperfusion, hypovolemia, vasoactive/pressor therapy, or medications such as acetaminophen >4 g/day, dopamine, vitamin C, or hydroxyurea.
- ▌ Es Pump Basal Rate Adaptation · dromlakhaniConsiders adapting the basal insulin rate at hospital admission for patients using insulin pump therapy. Triggered by clinician questions such as "Should we adjust the basal rate upon admission for pump therapy?" or when evaluating pump continuation versus transition to scheduled subcutaneous insulin.
- ▌ Es Pump Supplies Availability · dromlakhaniVerify that insulin pump supplies (provided by patient or family) will be available throughout the hospitalization to support continued pump use. Triggered by questions such as "Do we have sufficient pump supplies for the hospital stay?"
- ▌ Glp1 Gi Ae Symptom Advisor · dromlakhaniProvide symptom-specific dietary and lifestyle advice for a patient on a GLP-1 receptor agonist who has developed nausea, vomiting, diarrhoea, or constipation. Use when a clinician asks "what to advise for nausea/vomiting/diarrhoea/constipation on semaglutide/liraglutide/tirzepatide", or any GLP-1 patient with a specific GI symptom needs targeted non-pharmacological advice. Outputs a focused do/avoid list per symptom, grounded in the Gorgojo-Martínez 2023 consensus (Figure 2).
- ▌ Mounjaro Prescribing Guide · dromlakhaniBedside prescribing reference for Mounjaro (tirzepatide) — indications, dose escalation, missed-dose rule, KwikPen vs prefilled pen differences, contraindications, warnings, storage, and monitoring. Use when a clinician asks how to start tirzepatide, how to titrate Mounjaro, how to handle a missed weekly dose, Mounjaro storage, Mounjaro contraindications, Mounjaro pregnancy/MTC warnings, or needs a quick Mounjaro monograph lookup. Grounded in the Canadian Product Monograph (Eli Lilly Canada, April 2026).
- ▌ Endo T Baseline Followup Measurement · dromlakhaniRecommends measuring testosterone levels at baseline and after 3–6 weeks of initial treatment to assess for patient overuse or excessive dosing. Triggered when initiating testosterone therapy in women with hypoactive sexual desire disorder (HSDD) to verify levels remain within physiological range and avoid supratherapeutic dosing.
- ▌ Endo T Measurement Diagnosis Against · dromlakhaniThe guideline recommends against routinely measuring testosterone in women for diagnostic purposes due to the lack of a reliable correlation between symptoms and testosterone levels. This recommendation is triggered when a clinician orders a testosterone test to assess fatigue, low libido, or mood symptoms without evidence of underlying endocrine pathology.
- ▌ Es Ghc Hypoglycemia Safeguards · dromlakhaniThis skill guides clinicians to apply safeguards—including frequent point-of-care glucose monitoring and insulin dose adjustments—to prevent hypoglycemia when tapering or discontinuing glucocorticoids in hospitalized patients. Use when encountering triggers such as "Glucocorticoid being tapered, how to avoid hypoglycemia?" or "Stopping steroids, need to avoid low blood sugar."
- ▌ Es Scheduled Insulin Preferred · dromlakhaniIn most adult patients with hyperglycemia (with or without known type 2 diabetes) hospitalized for noncritical illness, scheduled insulin therapy is preferred over noninsulin agents for glycemic management. Clinicians should consider this when they ask, "Patient has hyperglycemia, should we start insulin or try a noninsulin drug?"
- ▌ Endo Statin Contraindication Pregnancy · dromlakhaniRecommends against using statins in women who are pregnant or trying to become pregnant. Trigger phrases include "Female patient of childbearing potential needing lipid therapy", "Assessing medication safety in pregnancy", "Considering statin for lipid disorder in pregnancy".
- ▌ Endo Statin Therapy T1d Ckd Stages 1 4 · dromlakhaniThis skill suggests statin therapy irrespective of cardiovascular risk score to reduce cardiovascular risk in adults with type 1 diabetes and chronic kidney disease stages 1-4. Clinical triggers include "Patient with T1D and CKD stages 1-4", "Assessing statin need in type 1 diabetic kidney disease", and "T1D with renal impairment".
- ▌ Endo Statin Therapy T2d Ckd Stages 1 4 · dromlakhaniThis skill suggests statin therapy irrespective of cardiovascular risk score to reduce cardiovascular risk in adults with type 2 diabetes and CKD stages 1-4 or postrenal transplant. Consider when encountering phrases such as "Patient with T2D and CKD stages 1-4", "T2D with renal transplant", or "Assessing statin need in diabetic kidney disease".
- ▌ Endo Paget Hearing Loss Prevention · dromlakhaniSuggests treatment with a potent bisphosphonate to prevent worsening of a hearing deficit in patients with Paget's disease involving the temporal bone. Triggers include detected or suspected hearing loss thought to be related to Paget's disease.
- ▌ Endo Paget Zoledronate Choice Dose · dromlakhaniSuggests a single 5‑mg intravenous dose of zoledronate as the treatment of choice in patients with active Paget’s disease who have no contraindication to IV zoledronate. Triggered when initiating pharmacologic therapy for Paget’s disease and confirming absence of renal impairment or other contraindications.
- ▌ Ata Ppgl Thyroid Block For Mibg · dromlakhaniThe skill recommends administering potassium iodide (50–150 mg/day) or Lugol's solution (5–10 drops/day) for three days prior to and continuing through the day of 123I-MIBG scintigraphy to reduce thyroid radiation exposure and prevent medullary thyroid cancer in patients undergoing evaluation for pheochromocytoma or paraganglioma. It is triggered when a clinician questions whether to give a thyroid blocking agent for a 123I-MIBG scan, such as when ordering 123I-MIBG scintigraphy for PPGL evaluation.
- ▌ Endo Avoid Gh Igf1 Monitoring Pregnancy · dromlakhaniThis skill advises against measuring GH or IGF-1 in pregnant patients with acromegaly because placental GH variant interferes with assay interpretation. Use when evaluating hormone testing in a pregnant acromegaly patient.
- ▌ Endo Discontinue Pegvisomant If Lftgt3x · dromlakhaniConsider discontinuing pegvisomant when alanine aminotransferase (ALT) or aspartate aminotransferase (AST) exceeds three times the upper limit of normal (ULN) during routine monthly liver function testing. This trigger applies to patients receiving pegvisomant for acromegaly who demonstrate transaminase elevations >3× ULN on LFT monitoring.
- ▌ Endo Trial Cabergoline Modest Igf1 Mild · dromlakhaniSuggests a trial of a dopamine agonist, usually cabergoline, as initial adjuvant therapy in patients with only modest IGF-1 elevations and mild GH excess symptoms after surgery. Use when postoperative IGF-1 is mildly elevated and symptoms of GH excess are mild.
- ▌ Endo Against 25ohd Test Pregnancy · dromlakhaniRecommends against routine 25(OH)D testing during pregnancy. Use when a clinician considers ordering 25(OH)D tests for pregnant patients lacking established indications such as hypocalcemia or malabsorption.
- ▌ T1d Islet Autoantibody Screening Confirmation · dromlakhaniOrder and confirm islet autoantibody screening for early-stage type 1 diabetes — which antibodies to test (GAD65, IAA, IA2, ZnT8), sample types (capillary dried blood spot, venous), the mandatory two-sample two-method confirmation protocol, and how to interpret a positive, negative, or single-antibody result. Use when a clinician asks how to screen for early T1D, which islet autoantibodies to order, how to confirm a positive T1D antibody screen, is one autoantibody enough for T1D diagnosis, GAD antibody positive what next, or is running a general population or family-history T1D screening program. Grounded in Hussain et al 2026 (Diabetes, Obesity and Metabolism, IDF Europe consensus, DOI 10.1111/dom.70569).
- ▌ T1d Progression Risk And Monitoring Frequency · dromlakhaniFor a person with confirmed islet autoantibodies (early-stage type 1 diabetes), state the numerical progression risk to Stage 3 T1D by stage and age, set the age-stratified monitoring frequency (metabolic and HbA1c), apply the ≥10% longitudinal HbA1c rise → OGTT rule, and give the standard risk-modifier and communication framing. Use when a clinician asks how often should I monitor this Stage 1 child, what's the risk of this teenager progressing to insulin, adult with GAD positive what's the 5-year risk, my patient's HbA1c has risen 12% is that important, single autoantibody how often to retest, or how to counsel a family about progression risk. Grounded in Phillip et al. Diabetologia 2024 international staging and monitoring consensus, cross-referenced with Hussain et al 2026 IDF Europe roadmap.
- ▌ Dbd Diabetes Hypertension Donor Eligibility · dromlakhaniDecide whether a kidney from a brain-dead deceased donor (DBD) with diabetes mellitus and/or hypertension is suitable for transplantation, using the ISOT 2025 Delphi consensus and Table 4 eligibility checklist. Trigger when a clinician asks "can I use a kidney from a diabetic deceased donor", "is this DBD with HTN/DM acceptable", "ECD donor with diabetes — accept or decline", "DBD eligibility for hypertensive donor", or shares a deceased donor with diabetes or hypertension and needs an accept/borderline/decline decision.
- ▌ Enda Glucocorticoid Injection Kit Training · dromlakhaniRecommends equipping every patient with primary adrenal insufficiency (PAI) with a glucocorticoid injection kit for emergency self‑administration and providing training on its use. Trigger when preparing a PAI patient for stress dosing, adrenal crisis prevention, or when prescribing glucocorticoid replacement and needing to ensure emergency preparedness.
- ▌ Enda Increase Hc Pregnancy Third Trimester · dromlakhaniRecommends increasing hydrocortisone dose in pregnant patients with primary adrenal insufficiency based on individual clinical course, especially during the third trimester. Trigger phrases include "fatigue, postural hypotension, weight loss, or hyperglycemia in pregnant PAI patient" and "need for glucocorticoid dose adjustment in third trimester."
- ▌ Enda Monitor Mineralocorticoid Replacement · dromlakhaniThis skill outlines monitoring of mineralocorticoid replacement in primary adrenal insufficiency, focusing on clinical assessment of salt craving, postural hypotension, or edema alongside serum electrolyte measurements. It is initiated when evaluating patients on fludrocortisone therapy to ensure adequate dosing and avoid over- or under-replacement.
- ▌ Es Cushing Multidisciplinary Team Approach · dromlakhaniThis skill recommends that a multidisciplinary team, including an experienced endocrinologist, incorporates patient values and preferences while providing education about treatment options for Cushing’s syndrome. Use when planning treatment for a CS patient requiring coordinated care; triggers include persistent hypercortisolism after transsphenoidal surgery, consideration of bilateral adrenalectomy, radiotherapy, or medical therapy, and need for shared decision‑making.
- ▌ Endo Assess Cgm Data Diff Smbg · dromlakhaniAssesses patient’s understanding of how CGM data (trends, rates of change) differ from discrete SMBG fingerstick values. Triggered when clinicians hear requests to explain lag and trend arrows on CGM or teach the difference between CGM glucose and fingerstick glucose.
- ▌ Endo Assess Emergency Supplies · dromlakhaniAssesses whether the patient has emergency supplies such as glucagon, ketone strips, and backup insulin readily available. Triggered when clinicians verify the patient carries a glucagon kit or ensure backup insulin and supplies are accessible.
- ▌ Es Rtcgm Adip Vs Mdis Smbg T1d · dromlakhaniThis skill suggests using real-time continuous glucose monitoring (CGM) and algorithm-driven insulin pumps (ADIPs) rather than multiple daily injections (MDIs) with self-monitoring of blood glucose (SMBG) three or more times daily for adults and children with type 1 diabetes (T1D). Trigger phrases include "Should I use RT-CGM+ADIP or MDI+SMBG for this T1D patient?" or "Is intensive pump therapy indicated for this patient?"
- ▌ Noveltreat Storage Handling · dromlakhaniStorage, handling, and disposal of the Noveltreat pre-filled semaglutide injection pen (0.25 / 0.5 / 1 / 2.4 mg, Sun Pharma) — fridge rules, 28-day out-of-fridge limit, single-use, pen-lock mechanism, light and freeze precautions, biomedical-waste disposal. Use when a clinician, pharmacist, or patient asks how to store Noveltreat, whether the pen can be kept outside the fridge, how long Noveltreat is stable at room temperature, how to dispose of a used Noveltreat pen, or what to do with an accidentally frozen / dropped / exposed pen. Grounded in Sun Pharmaceutical Industries Ltd. Product Monograph — Diabetes and Obesity (2026).
- ▌ Endo Hirsutism Screen Nccah High Risk · dromlakhaniThis skill screens high‑risk patients for nonclassic congenital adrenal hyperplasia (NCCAH) by measuring 17‑OHP even when total and free testosterone are normal. Use when a clinician says, "She has a family history of CAH; should we still screen despite normal androgens?" or notes positive family history or high‑risk ethnic group.
- ▌ Icsm Avoid Testosterone Acute Illness · dromlakhaniAdvises against obtaining testosterone levels during acute illness as results may be unreliable. Triggers when a patient is febrile, infected, or otherwise acutely unwell and the clinician questions whether to draw testosterone now or delay testing until recovery.
- ▌ Icsm Avoid Tt For Diabetes Prevention · dromlakhaniThe guideline recommends against using testosterone therapy alone to prevent or treat diabetes in men with hypogonadism. Clinicians should consider this recommendation when contemplating testosterone to improve HbA1c or insulin resistance and questioning whether testosterone can replace glucose-lowering therapy or be used for diabetes management.
- ▌ Icsm Choose Testosterone Assay Method · dromlakhaniRecommends mass spectrometry for research purposes and good-quality immunoassays for routine clinical diagnosis when standardized against an international reference range. Triggers when a clinician orders a testosterone test and asks "which assay should I use?" or questions "is this immunoassay reliable enough?"
- ▌ Icsm Defer Tt Elevated Psa Or Nodules · dromlakhaniRecommends postponing testosterone initiation and pursuing MRI or biopsy when PSA is elevated or a prostate nodule is detected on digital rectal examination; if evaluation shows no cancer, testosterone therapy may be considered. Triggered by clinician findings of elevated PSA (>4 ng/mL) or a palpable prostate nodule during DRE, prompting the question of whether to hold testosterone until prostate cancer is ruled out.
- ▌ Icsm Morning Testosterone Measurement · dromlakhaniRecommends measuring total testosterone in the morning fasting state (07:00–11:00) using a reliable assay for patients suspected of hypogonadism. Triggered when a clinician orders a testosterone test and questions whether the sample should be drawn fasting and in the morning.
- ▌ Icsm Physical Exam Hypogonadism Signs · dromlakhaniAdvises checking for smaller testes, decreased body hair, and gynecomastia as physical clues to hypogonadism. Triggered when evaluating a man with suspected testosterone deficiency who asks what physical exam findings support the diagnosis or whether any exam signs suggest hypogonadism.
- ▌ Icsm Testosterone Monitoring Schedule · dromlakhaniThis skill outlines the monitoring schedule for testosterone therapy, detailing baseline, 3‑month, 6‑month, and yearly assessments of symptoms, adverse events, total testosterone, hematocrit, PSA, and DRE. Use it when a patient is receiving testosterone and the clinician asks what labs and checks are needed today or when the next monitoring visit should occur.
- ▌ Es Basal Insulin Dose Reduction · dromlakhaniConsider reducing basal insulin dose by 10% to 20% at hospitalization for patients on basal heavy insulin regimens (≥0.6–1.0 units/kg/day) to prevent over‑coverage of meal‑related glucose excursions. Trigger phrases include “Patient on high basal insulin dose, should we reduce it during hospital stay?” and “Basal insulin dose ≥0.6 U/kg/day, consider reduction on admission.”
- ▌ Endo Statin Therapy T2d Cv Risk Factors · dromlakhaniRecommends statin therapy in addition to lifestyle modification to reduce cardiovascular risk in adults with type 2 diabetes and additional cardiovascular risk factors such as hypertension, dyslipidemia, smoking, or family history of premature ASCVD. Use when managing a patient with type 2 diabetes who has concomitant hypertension, LDL‑C >70 mg/dL, or other risk‑enhancing factors.
- ▌ Ata Gc Overreplacement Osteoporosis · dromlakhaniIndividually assesses glucocorticoid replacement to avoid over-replacement and reduce osteoporosis risk by suggesting low-dose hydrocortisone to increase bone formation and promote positive bone-remodeling balance. Triggered when managing patients on long-term glucocorticoid therapy requiring osteoporosis risk assessment.
- ▌ Endo Comorbidities Longitudinal Monitoring · dromlakhaniThis skill recommends longitudinal monitoring and rigorous management of identified comorbidities—such as hypertension, diabetes mellitus, cardiovascular disease, osteoarthritis, and sleep apnea—in patients with acromegaly. Apply throughout follow‑up when comorbidities are present to mitigate morbidity and mortality risk.
- ▌ Ata Ppgl Chemotherapy Indication · dromlakhaniRecommends CVD chemotherapy as first-line systemic treatment for unresectable pheochromocytoma/paraganglioma with rapid progression or when radionuclide therapy is not applicable. Considers disease progression rate and feasibility to choose between CVD chemotherapy and radionuclide therapy in patients with positive nuclear imaging when progression is slow and radionuclide therapy feasible.
- ▌ Pheo Preoperative Alpha Blockade · dromlakhaniPre-operative preparation protocol for Pheochromocytoma, focusing on alpha-blockade titration and volume expansion. Trigger when a clinician asks "prep for pheo surgery", "alpha blockade vs beta blockade", or "doxazosin titration".
- ▌ Ppgl Confirmation Test Selection · dromlakhaniSelects the appropriate functional confirmation test after a positive PPGL screening test to establish biochemical diagnosis. Triggered by statements such as 'Screening test positive for PPGL,' 'Need to confirm PPGL diagnosis before imaging,' or 'Biochemical test results exceed screening thresholds.'
- ▌ Ppgl Lifelong Follow Up Duration · dromlakhaniDetermines appropriate postoperative follow-up duration for PPGL based on hereditary status, catecholamine phenotype, tumor size, and location to guide surveillance intensity. Recommends lifelong follow-up for hereditary PPGL and at least 10 years for sporadic PPGL with noradrenaline dominance, tumor ≥5 cm, or extra‑adrenal/PGL location; triggers include 'Post-op PPGL patient requiring follow-up plan,' 'Assessing need for extended surveillance in PPGL survivor,' 'Determining follow-up duration for cured PPGL patient.'
- ▌ Ppgl Pediatric Surgical Approach · dromlakhaniDetermines surgical approach for PPGL in children considering tumor size, suspected pathogenic gene variants, and hereditary tumor syndromes. Chooses between laparotomy and endoscopic surgery based on child's size and genetic risk; incorporates family history and genetic testing results in decision-making, with triggers such as 'Child diagnosed with PPGL requiring surgery,' 'Need to select surgical approach for pediatric PPGL,' and 'Evaluating surgical options in child with genetic syndrome.'
- ▌ Ppgl Pregnancy Imaging Selection · dromlakhaniSelects safe imaging modalities for PPGL evaluation in pregnancy to minimize fetal radiation exposure, preferring ultrasound or MRI and reserving CT or 123I-MIBG scintigraphy for cases where diagnostic benefits outweigh radiation risks after informed consent. Triggered by phrases such as 'Pregnant patient with suspected PPGL symptoms,' 'Need imaging for PPGL in pregnant patient,' or 'Evaluating PPGL while minimizing fetal radiation risk.'
- ▌ Ppgl Surgical Approach Selection · dromlakhaniThis skill selects the surgical approach (laparoscopic/robot-assisted vs open adrenalectomy) for pheochromocytoma and paraganglioma (PPGL) based on tumor size and suspected organ invasion. It is triggered when imaging shows PPGL tumor size approaching 6 cm, suspected tumor invasion into adjacent structures on imaging, or when determining the surgical approach for a confirmed PPGL.
- ▌ Ata Postmenopausal Gonadotrope Diagnosis · dromlakhaniDiagnoses gonadotrope dysfunction in postmenopausal women by confirming absent high serum FSH and LH when not on hormone replacement therapy. Use when evaluating a postmenopausal woman for hypogonadism; triggers include postmenopausal woman with suspected hypogonadism.
- ▌ Ata Postop Pituitary Apoplexy Monitoring · dromlakhaniRecommends that clinicians monitor pituitary axes in pituitary apoplexy patients treated with surgical decompression or conservative management because hypopituitarism may develop over time. Use when managing pituitary apoplexy patient; triggers include pituitary apoplexy patient needing longitudinal monitoring.
- ▌ Endo Repeat Surgery Residual Intrasellar · dromlakhaniSuggests considering repeat surgery in patients with residual intrasellar disease after initial surgical resection. Consider when postoperative imaging demonstrates persistent intrasellar tumor.
- ▌ Es Short Stature High Risk Screen · dromlakhaniThis skill identifies childhood cancer survivors at high risk for short adult height based on cranial/spinal/total body irradiation at a young age or a history of inadequate weight gain or prolonged steroid requirement. It is triggered by questions such as "Does this survivor need growth monitoring?" or "Is this patient high-risk for growth impairment?"
- ▌ Enda Fludrocortisone Aldosterone Deficiency · dromlakhaniRecommends initiating fludrocortisone 50–100 µg daily for mineralocorticoid replacement in adults with confirmed aldosterone deficiency (e.g., low aldosterone, elevated renin) and no salt restriction. Use when aldosterone deficiency is confirmed in a patient with primary adrenal insufficiency (PAI) presenting with salt craving or postural hypotension.
- ▌ Enda Pediatric Fludrocortisone Infants Nacl · dromlakhaniRecommends fludrocortisone 100 µg daily for children with primary adrenal insufficiency and confirmed aldosterone deficiency; for infants under 12 months, adds sodium chloride supplementation. Triggered by PAI with aldosterone deficiency, evidenced by salt craving, hyponatremia, hyperkalemia, or elevated renin with low aldosterone.
- ▌ Es Hcm Ugps1 Iv Fluids First Line · dromlakhaniRecommends initiating intravenous isotonic saline hydration as initial management for hypercalcemia of malignancy (HCM) while awaiting antiresorptive therapy, with fluid rate adjusted according to cardiac function. Triggered when a clinician encounters a patient with HCM (e.g., serum calcium >12 mg/dL, symptoms of hypercalcemia) and seeks immediate measures before specific drugs are available.
- ▌ Hypercalcemia Severity Classifier · dromlakhaniClassify the severity of hypercalcemia at the bedside — mild, moderate, or severe — by combining the corrected/ionized calcium level with the acuity and symptom pattern, and decide whether the patient needs urgent therapy. Trigger when a clinician asks "is this hypercalcemia severe", "how bad is this calcium level", "when to admit for hypercalcemia", "is this hypercalcemic crisis", "how to grade hypercalcemia", or shares a calcium level and asks how worried to be.
- ▌ Es Cushing Against Treatment Borderline Hpa · dromlakhaniThis skill recommends against initiating treatments aimed at normalizing cortisol or its action when only borderline biochemical abnormalities of the hypothalamic-pituitary-adrenal (HPA) axis are present without specific signs of Cushing's syndrome. Use when encountering borderline urinary free cortisol, late-night salivary cortisol, or dexamethasone suppression test results without classic Cushingoid features; triggers include borderline UFC (1-2× ULN), equivocal late-night salivary cortisol, or nondiagnostic low-dose DST.
- ▌ Es Cushing Initial Resection Recommendation · dromlakhaniRecommends initial surgical resection of the primary lesion(s) causing Cushing's syndrome when surgery is feasible and likely to significantly reduce glucocorticoid excess. Trigger phrases include overt Cushing's syndrome, ACTH-dependent CS, ectopic ACTH secretion, adrenal adenoma, bilateral macronodular adrenal hyperplasia, and persistent hypercortisolism.
- ▌ Es Cushing Serum Sodium Monitoring Post Tss · dromlakhaniThis skill recommends measuring serum sodium several times during the first 5–14 days after transsphenoidal surgery to detect and manage electrolyte disturbances such as postoperative hyponatremia and diabetes insipidus. Use when managing a post-TSS Cushing’s syndrome patient in the early recovery phase; triggers include postoperative day 5–10 hyponatremia, polyuria, fluid intake‑output imbalance, or suspected diabetes insipidus.
- ▌ Pdm Postpartum Endocrine Care · dromlakhaniRecommends postpartum endocrine care (diabetes management) in addition to usual obstetric care for individuals with preexisting diabetes (including those with pregnancy loss or termination). Triggered by postpartum care planning for patients with diabetes after delivery.
- ▌ Endo Assess Cgm Alarms Settings · dromlakhaniAssesses that CGM low- and high-glucose alarm thresholds are individualized to optimize patient benefit and minimize alarm fatigue. Triggered by clinician prompts to 'Review low-glucose alarm thresholds' or 'Ensure alarms are individualized and not excessive'.
- ▌ Glp1 Candidacy Myths Checker · dromlakhaniDecide whether commonly-excluded patients (eating disorders, elderly ≥75, upper GI disease) can actually receive a GLP-1 receptor agonist. Use when a clinician asks "can I give semaglutide to a patient with binge eating disorder / anorexia / bulimia", "is liraglutide safe in an 80-year-old", "GLP-1 with GERD or chronic gastritis", "GLP-1 in sarcopenic elderly", or anytime a patient is being ruled out for GLP-1 therapy based on a perceived contraindication. Grounded in Gorgojo-Martínez 2023 §6 (Myths or Reality).
- ▌ Glp1 Gi Ae Patient Education · dromlakhaniCounsel a patient before starting a GLP-1 receptor agonist (semaglutide, liraglutide, dulaglutide, exenatide, lixisenatide, oral semaglutide) on how to prevent GI adverse events — nausea, vomiting, diarrhoea, constipation. Use when a clinician asks for patient-education material, a GLP-1 starter handout, pre-initiation counselling, or "what should I tell my patient before starting Ozempic/Wegovy/Rybelsus/Victoza/Saxenda/Trulicity." Produces a structured patient-facing brief grounded in the Gorgojo-Martínez 2023 multidisciplinary consensus.
- ▌ Noveltreat Prescribing Guide · dromlakhaniBedside prescribing reference for Noveltreat (Sun Pharma semaglutide 0.25/0.5/1/1.7/2.4 mg pre-filled pen) for chronic weight management — adult indication criteria, 5-step dose escalation, missed-dose rule, contraindications, warnings, drug interactions, and red-flag stop signals. Use when a clinician asks how to start Noveltreat, how to titrate semaglutide 2.4 mg, Noveltreat missed dose, Noveltreat contraindications, Noveltreat drug interactions, or when a patient on Noveltreat needs a monograph-level clinical decision. Grounded in Sun Pharmaceutical Industries Ltd. Product Monograph — Diabetes and Obesity (2026).
- ▌ Wegovy Pediatric Eligibility · dromlakhaniCheck whether an adolescent aged 12 to under 18 years qualifies for Wegovy (semaglutide 2.4 mg) using BMI age-sex 95th-percentile cutoff, weight above 60 kg threshold, and secondary-obesity exclusion. Use when a clinician asks "is my teenager eligible for Wegovy", "Wegovy in adolescents", "pediatric semaglutide 2.4 mg indication", or needs to screen a 12 to 17 year-old with obesity before initiation. Grounded in the Wegovy Canadian Product Monograph (Novo Nordisk, March 2024).
- ▌ Endo Fha Inpatient Evaluation Criteria · dromlakhaniThis skill guides clinicians to assess patients with functional hypothalamic amenorrhea (FHA) for hospital admission when they exhibit severe bradycardia, hypotension, orthostasis, or significant electrolyte abnormalities. Use when a clinician says, “Her heart rate is 40 and she’s dizzy—should we admit her?” or notes phrases like “Admit for hypotension and bradycardia” or “Check for orthostatic vitals and electrolytes.”
- ▌ Endo Fha Rpth Delayed Fracture Low Bmd · dromlakhaniThis skill suggests that short-term recombinant parathyroid hormone 1-34 (rPTH) may be considered in rare adult functional hypothalamic amenorrhea (FHA) cases with delayed fracture healing and markedly reduced bone mineral density. Use when a clinician notes, 'Her fracture isn’t healing and her Z-score is -3—could rPTH help?' or considers rPTH for poor fracture healing or teriparatide in severe osteoporosis with FHA.
- ▌ Endo Hirsutism Screen Nccah Amenorrhea · dromlakhaniOrders early morning 17‑hydroxyprogesterone to screen for nonclassic congenital adrenal hyperplasia due to 21‑hydroxylase deficiency in hyperandrogenemic women with amenorrhea or infrequent menses. Triggered by menstrual irregularity with hirsutism and a clinical request to rule out adrenal hyperplasia.
- ▌ Icsm Avoid Tt For Depressive Disorders · dromlakhaniTestosterone monotherapy is not an effective treatment for clinical depressive disorders in hypogonadal men and should not be used for that purpose. Consider this when a patient presents with depressive mood and low testosterone, questioning whether testosterone will improve depression or if depression should be treated separately.
- ▌ Es Discharge Planning Components · dromlakhaniThis skill outlines the core components to include in comprehensive diabetes discharge planning for hospitalized adults. It is triggered by questions such as "What should be included in diabetes discharge planning?" and ensures education on survival skills, referral for outpatient DSMES, follow-up scheduling, and medication/supply access.
- ▌ Endo Pharmacologic Treatment Tg Over 500 · dromlakhaniRecommends pharmacologic treatment as adjunct to diet and exercise to prevent pancreatitis in adults with fasting triglyceride levels >500 mg/dL. Triggered when evaluating a patient with an endocrine disorder who presents with fasting TG >500 mg/dL (severe hypertriglyceridemia) and no contraindication to pharmacologic therapy.
- ▌ Endo Statin Considerations Over 75 Years · dromlakhaniAdvises that continuation or initiation of statin treatment in patients over 75 years depends on atherosclerotic cardiovascular disease risk, prognosis, potential interacting medications, polypharmacy, mental health, and patient wishes. Common clinical triggers for using this skill are 'Elderly patient needing statin assessment', 'Statins in octogenarian with lipid disorder', and 'Balancing risks/benefits of statin in advanced age'.
- ▌ Endo Paget Early Response Assessment · dromlakhaniThis skill outlines using short-term changes in bone resorption markers (e.g., serum CTx or urine NTx) before and shortly after bisphosphonate therapy to predict an adequate therapeutic response. It is triggered when there is urgency to control severe symptoms or when Paget’s disease is highly active, prompting rapid efficacy assessment.
- ▌ Endo Paget Remission Target Turnover · dromlakhaniSuggests reducing bone turnover below the midpoint of the reference range for the chosen monitoring bone turnover marker to maximize the duration of remission. Triggered when aiming to sustain long-term remission after treatment and the marker exceeds the midpoint.
- ▌ Eso Pediatric Obesity Screen Time · dromlakhaniRecommends limiting non-academic screen time to 1-2 hours per day and decreasing other sedentary behaviors. Trigger phrases include "excessive screen time," "digital activities," and "sedentary behaviors."
- ▌ Ata Ppgl Screening Test Selection · dromlakhaniChooses the initial screening test for suspected pheochromocytoma and paraganglioma when evaluating hypertension with paroxysmal symptoms, adrenal incidentaloma, or family history of PPGL. Selects among random urinary fractionated metanephrines (creatinine corrected), blood fractionated catecholamines, or plasma-free fractionated metanephrines.
- ▌ Ppgl 68ga Dotatate Pet Indication · dromlakhaniDetermines when to use 68Ga-DOTATATE PET for diagnosing primary head and neck paragangliomas irrespective of genetic variants. Triggers include suspected head/neck PGL requiring sensitive detection, evaluating for SSTR-positive neuroendocrine tumor, and pre-assessment for 177Lu-DOTATATE therapy in HNPGL.
- ▌ Ata Pituitary Apoplexy Gc Until Diagnosis · dromlakhaniAdministers glucocorticoid coverage in patients with pituitary apoplexy to prevent adrenal crisis while awaiting definitive laboratory diagnosis. Triggers include managing a pituitary apoplexy patient needing glucocorticoid coverage until laboratory confirmation of pituitary function.
- ▌ Endo Vitd No Supplementation 50to74 · dromlakhaniRecommends against routine vitamin D supplementation beyond the Dietary Reference Intake in adults aged 50-74 years without established indications for vitamin D treatment. Triggers include clinician questions such as "Should I prescribe vitamin D to this middle-aged adult?" or "Is vitamin D supplementation needed for patients aged 50-74?"
- ▌ Endo Vitd Supplementation Pregnancy · dromlakhaniSuggests empiric vitamin D supplementation during pregnancy to lower the risk of preeclampsia, intra-uterine mortality, preterm birth, small-for-gestational-age birth, and neonatal mortality. Triggered by clinician questions such as "Should I prescribe vitamin D to this pregnant patient?" or "Is vitamin D supplementation indicated for pregnant patients?"
- ▌ Genryzon Drug Interactions · dromlakhaniDrug-interaction and co-medication adjustment reference for a child on Genryzon (somatrogon, weekly long-acting growth hormone). Covers glucocorticoids, insulin and oral hypoglycaemics, thyroxine, oral estrogen, and CYP3A4-metabolised drugs (sex steroids, corticosteroids, anticonvulsants, ciclosporin). Use when a clinician asks about drug interactions with Genryzon or somatrogon, prescribing another drug in a child on GH, girl on Genryzon starting OCP, diabetic child starting GH, adjusting hydrocortisone on GH, or CYP3A4 concerns with somatrogon. Grounded in the Pfizer India Product Monograph (Genryzon LPD, 2022 — PfLEET 2022-0081166).