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drugclaw

@drugclaw source repo

26 published skills

  1. Weather · drugclaw
    Get current weather and short forecasts quickly using `wttr.in` (no API key required). Use when users ask for weather by city/region.
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  2. Apple Notes · drugclaw
    Manage Apple Notes on macOS using the `memo` CLI. Use this when users ask to create, list, search, edit, move, or export Apple Notes.
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  3. Apple Calendar · drugclaw
    Query and manage Apple Calendar on macOS via `icalBuddy` (read) and AppleScript (`osascript`) for event creation. Use when users ask about upcoming events or adding calendar events.
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  4. Apple Reminders · drugclaw
    Manage Apple Reminders on macOS using `remindctl` (list, add, edit, complete, delete, and list management). Use when users ask for reminders or task-list operations in Apple Reminders.
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  5. Chem Tools · drugclaw bundle
    Computational chemistry workflow guide for DeepChem, PySCF, RDKit, assay-table normalization, PDBbind-style structure datasets, QSAR and structure benchmarks, DrugBank lookup, ligand-only and structure-aware affinity prediction, ADMET triage, bioactivity prediction, virtual screening, and docking follow-up.
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  6. Bio Tools · drugclaw
    Bioinformatics workflow guide for sequence analysis, QC, plotting, structure rendering, and literature search.
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  7. Grn Tools · drugclaw bundle
    Gene regulatory network workflow guide for transcriptomics and single-cell expression matrices using Arboreto, GRNBoost2, and GENIE3. Use when the user asks to infer transcription factor-target links, score regulatory edges, or build a GRN from bulk or single-cell expression data.
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  8. Omics Tools · drugclaw bundle
    Omics and single-cell workflow guide for AnnData, Scanpy-style dataset profiling, PyDESeq2-oriented count checks, pysam alignment inspection, and pyOpenMS mass-spectrometry summaries. Use when the user asks to inspect h5ad files, summarize BAM regions, profile omics count tables, or inventory mzML experiments before deeper modeling.
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  9. Find Skills · drugclaw
    Find reusable skills from the vercel-labs/skills registry (especially by task keywords), evaluate fit, and suggest how to install/adapt them for DrugClaw.
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  10. Docking Tools · drugclaw bundle
    Molecular docking workflow guide and reusable pipeline template for AutoDock Vina, Open Babel, and PyMOL.
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  11. Bio DB Tools · drugclaw bundle
    Query public biology databases and APIs including UniProt, RCSB PDB, AlphaFold DB, ClinVar, dbSNP, gnomAD, Ensembl, GEO, InterPro, KEGG, OpenTargets, Reactome, and STRING. Use when the user asks to look up protein annotations, structures, variants, population frequencies, pathway knowledge, public datasets, interaction networks, or disease-target evidence.
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  12. Pharma DB Tools · drugclaw bundle
    Query public drug-discovery and translational-research databases including PubChem, ChEMBL, BindingDB, openFDA, ClinicalTrials.gov, and OpenAlex. Use when the user asks to look up compounds, measured binding affinities, regulatory labels or adverse events, clinical trials, or drug-discovery literature from public APIs and curated exports.
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  13. Pharma Ml Tools · drugclaw bundle
    Pharmaceutical machine-learning workflow guide for library profiling, molecular featurization, benchmark dataset fetch, medicinal-chemistry filtering, and optional pose-generation handoff. Use when the user asks for datamol, molfeat, PyTDC, medchem, compound-library triage, dataset preparation, or chemistry-ML baselines beyond simple descriptor calculation.
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  14. Medical Qms Tools · drugclaw
    Medical quality-system and documentation workflow guide for ISO 13485, FDA QMSR, design controls, risk management, CAPA, document control, supplier qualification, complaint handling, and audit preparation. Use when the user asks to plan, review, or gap-assess medical-device or diagnostic quality documentation without asking for legal determinations or regulatory guarantees.
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  15. Medical Data Tools · drugclaw bundle
    Medical data workflow guide for DICOM metadata inspection and basic de-identification, physiological signal analysis with NeuroKit2, and cohort-table profiling for clinical research datasets. Use when the user asks to inspect imaging metadata, summarize ECG/PPG/EDA/RSP/EMG signals, or profile tabular medical datasets without making patient-specific diagnoses or treatment decisions.
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  16. Stat Modeling Tools · drugclaw bundle
    Statistical modeling workflow guide for hypothesis tests, effect-size reporting, statsmodels regression, diagnostics, and structured result export. Use when the user asks for statistical test selection, OLS or logistic regression, coefficient tables, inference, or reproducible statistical summaries for scientific datasets.
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  17. Knowledge Graph Tools · drugclaw bundle
    Drug-discovery knowledge-graph workflow guide for assembling drug-target-disease-pathway relationship graphs from OpenTargets GraphQL, ChEMBL REST, STRING PPI, and Reactome pathway APIs, then running hub detection, shortest-path queries, and neighborhood expansion with networkx. Use when the user asks to build, query, or visualize a biomedical knowledge graph connecting drugs, targets, diseases, and pathways from real public databases without making clinical claims.
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  18. Variant Analysis Tools · drugclaw bundle
    Variant and VCF workflow guide for local SNV, indel, and structural-variant summarization, filtering, and consequence triage. Use when the user asks to inspect a VCF, count mutation classes, filter by VAF or depth, summarize genes or consequences, or prepare a local variant report before downstream annotation.
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  19. Clinical Research Tools · drugclaw
    Clinical research workflow guide for protocol design, endpoint selection, evidence grading, reporting-guideline selection, statistical planning, and clinical-trial evidence synthesis. Use when the user asks to design or review human-subjects research, trial analyses, observational studies, study protocols, CSRs, or clinical evidence summaries without requesting patient-specific diagnosis or treatment decisions.
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  20. Literature Review Tools · drugclaw bundle
    Research-literature workflow guide for evidence-matrix assembly, citation-table normalization, structured review synthesis, and research-gap mapping. Use when the user asks for systematic or scoped literature review workflows, citation cleanup, evidence tables, or manuscript-ready review preparation for drug-discovery and biomedical topics.
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  21. Survival Analysis Tools · drugclaw bundle
    Survival and time-to-event workflow guide for Kaplan-Meier summaries, log-rank tests, and Cox proportional hazards models with reproducible outputs. Use when the user asks for time-to-event analysis, censored data summaries, hazard ratios, or survival-group comparison for research datasets.
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  22. Scientific Workflow Tools · drugclaw bundle
    Research-method workflow guide for hypothesis framing, peer-review style critique, reproducibility planning, study-design checks, and scientific-writing structure. Use when the user asks for manuscript critique, research-gap framing, hypothesis generation, reproducibility checklists, or study-planning support that should stay on the research side rather than patient-care decisions.
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  23. Target Intelligence Tools · drugclaw bundle
    Target research workflow guide for building compact drug-target dossiers across protein identity, disease evidence, known drugs, interaction partners, pathways, and variant constraint signals. Use when the user asks for a target brief, target validation snapshot, or a one-file summary of what is known about a gene or protein target.
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  24. Patent Landscape Tools · drugclaw bundle
    Drug-patent landscape workflow guide for searching US patents via the PatentsView API, classifying pharmaceutical claim types (NCE, formulation, method-of-use, polymorph, combination, biologic, process), grouping by patent family and assignee, estimating expiry timelines, and cross-referencing the FDA Orange Book for marketed-drug exclusivity windows. Use when the user asks about patent coverage, IP white-space, patent cliffs, or competitive filing activity around a drug, target, or compound class without asking for legal counsel.
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  25. Bayesian Optimization Tools · drugclaw bundle
    Bayesian optimization workflow guide for experiment suggestion, condition tuning, and closed-loop parameter search with Gaussian-process surrogates. Use when the user asks which experiment to try next, how to tune reaction or assay conditions, or how to balance exploration versus exploitation over a bounded numeric search space.
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  26. Scientific Visualization Tools · drugclaw bundle
    Scientific visualization workflow guide for publication-ready static figures with seaborn or matplotlib and interactive figures with Plotly. Use when the user asks for scientific plots, cohort or assay figures, publication graphics, dashboards, or reusable plotting scripts for research datasets.
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